AZSITA TRIO 500MG TABLET 10'S

How AZSITA TRIO 500MG TABLET 10'S Works

• AZSITA TRIO 500MG TABLET 10'S is a combination medication designed to manage type 2 diabetes effectively. It combines three active ingredients: Metformin, Sitagliptin, and Pioglitazone, each working through distinct mechanisms to control blood sugar levels.
• Metformin is a biguanide that primarily reduces glucose production in the liver. It achieves this by suppressing hepatic gluconeogenesis, the process where the liver generates glucose from non-carbohydrate sources. Additionally, Metformin enhances insulin sensitivity in peripheral tissues, such as muscles, allowing cells to utilize glucose more efficiently. It also slows down the absorption of glucose from the intestines, further contributing to lower blood sugar levels after meals.
• Sitagliptin belongs to a class of drugs called DPP-4 inhibitors. DPP-4 (dipeptidyl peptidase-4) is an enzyme that breaks down incretin hormones in the body. Incretins, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), play a crucial role in regulating blood sugar by stimulating insulin release from the pancreas and suppressing glucagon secretion. By inhibiting DPP-4, Sitagliptin increases the levels of active incretins, thereby enhancing insulin secretion in response to elevated blood glucose and reducing glucagon levels, particularly after meals. This helps to improve postprandial glucose control.
• Pioglitazone is a thiazolidinedione (TZD) that works by increasing the sensitivity of body tissues to insulin. It primarily targets fat and muscle cells, making them more responsive to insulin's effects. Pioglitazone activates PPARγ (peroxisome proliferator-activated receptor gamma), a nuclear receptor that regulates the expression of genes involved in glucose and lipid metabolism. By improving insulin sensitivity, Pioglitazone allows cells to take up and utilize glucose more efficiently, reducing insulin resistance and lowering blood sugar levels. It also helps to improve lipid profiles in some patients.
• In summary, AZSITA TRIO 500MG TABLET 10'S leverages the complementary actions of Metformin, Sitagliptin, and Pioglitazone to provide comprehensive glycemic control. Metformin reduces glucose production in the liver and enhances insulin sensitivity, Sitagliptin enhances incretin activity to stimulate insulin release and suppress glucagon, and Pioglitazone improves insulin sensitivity in peripheral tissues. This triple-pronged approach helps to maintain stable blood sugar levels throughout the day, particularly after meals, making it an effective treatment option for individuals with type 2 diabetes.
• Always use this medicine as prescribed by your doctor. Do not self-medicate.

The following side effects may occur while taking AZSITA TRIO 500MG TABLET 10'S. It is important to consult with your doctor if you experience any of these or any other unusual symptoms: **Common Side Effects:** * Nausea * Vomiting * Diarrhea * Abdominal pain * Loss of appetite * Metallic taste * Headache * Dizziness * Weakness * Hypoglycemia (low blood sugar) - especially when taken with other diabetes medications **Uncommon Side Effects:** * Skin rash or itching * Upset stomach * Flatulence * Constipation * Heartburn * Muscle pain * Joint pain * Edema (swelling) in the legs or ankles * Changes in liver function tests * Vitamin B12 deficiency * Lactic acidosis (rare but serious) - symptoms include feeling very weak or tired, unusual muscle pain, trouble breathing, stomach pain with nausea and vomiting, feeling cold, dizziness or lightheadedness, and a slow or irregular heartbeat. Seek immediate medical attention if you experience these. * Allergic reactions (rare) - symptoms may include hives, difficulty breathing, and swelling of the face, lips, tongue, or throat. This is not an exhaustive list, and other side effects may occur. Contact your doctor or pharmacist for medical advice about side effects. You can also report side effects to your local regulatory authority.

• If you miss a dose of AZSITA TRIO 500MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose to catch up.

• Keep AZSITA TRIO 500MG TAB 1X10 away from the reach of children and pets.
• Store AZSITA TRIO 500MG TAB 1X10 at room temperature.

• Take AZSITA TRIO 500MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider, as this could lead to uncontrolled blood sugar levels. Consistency is key to effectively managing your diabetes.
• AZSITA TRIO 500MG TABLET 10'S is most effective when taken with meals. This helps to improve the absorption of the medication and reduces the risk of stomach upset. Follow your doctor's instructions regarding the timing of your doses in relation to food intake for optimal results. Usually it is advised to take it with your first main meal.
• While taking AZSITA TRIO 500MG TABLET 10'S, it's crucial to monitor your blood sugar levels regularly. This helps you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Keep a record of your blood sugar readings and share them with your healthcare provider during check-ups.
• AZSITA TRIO 500MG TABLET 10'S works best when combined with a healthy lifestyle. This includes following a balanced diet, engaging in regular physical activity, and maintaining a healthy weight. These lifestyle changes can significantly improve your blood sugar control and overall health. Try to aim for at least 30 minutes of moderate-intensity exercise most days of the week.
• Be aware of the potential side effects of AZSITA TRIO 500MG TABLET 10'S, such as nausea, diarrhea, or stomach pain. If you experience any bothersome or persistent side effects, inform your doctor promptly. They can provide guidance on how to manage these side effects or adjust your medication if necessary. Also, stay hydrated and avoid excessive alcohol consumption while taking this medication.

• AZSITA TRIO 500MG TABLET 10'S is generally taken with or without food but it's best to take it at a fixed time to maintain consistent blood sugar levels.
• Avoid excessive alcohol consumption while taking this medicine, as it can increase the risk of low blood sugar (hypoglycemia) and other side effects.
• Dietary adjustments, as recommended by your doctor or a registered dietitian, are important while taking this medication to manage blood sugar levels effectively.