BEVACIREL 400MG/16ML INJECTION
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BEVACIREL 400MG/16ML INJECTION
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BEVACIREL 400MG/16ML INJECTION

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BEVACIREL 400MG/16ML INJECTION

By RELIANCE LIFE SCIENCES

MRP

56889.56

₹15929

72 % OFF

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Product Details
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About BEVACIREL 400MG/16ML INJECTION

  • BEVACIREL 400MG/16ML INJECTION is a powerful medicine used to fight certain types of cancer. Its active ingredient is Bevacizumab. This medicine works by targeting the blood vessels that supply tumors. By blocking the growth of these blood vessels, it helps to slow down or stop the growth and spread of the cancer cells. BEVACIREL 400MG/16ML INJECTION is typically used alongside other cancer drugs (chemotherapy) because this combination often works better at attacking the cancer.
  • Doctors prescribe BEVACIREL 400MG/16ML INJECTION to treat several kinds of cancer that have spread (metastatic). These include metastatic breast cancer, certain types of brain cancer, cervical cancer, kidney cancer, lung cancer, and colorectal cancer. It's also an important treatment for cancers affecting the ovary, fallopian tube, or the primary peritoneal area. This medicine is not suitable for children and adolescents under 18 years of age.
  • It's very important to use effective birth control methods while you are being treated with BEVACIREL 400MG/16ML INJECTION and for at least six months after your final dose. This is because the medicine could potentially harm a developing baby. If you are a woman and planning to have children in the future, talk to your doctor about preserving your fertility before starting treatment, as this medicine might affect your ovaries and ability to get pregnant later. Breastfeeding is also not recommended during treatment, as the medicine could pass into breast milk and affect your baby's growth and development.
  • Before you start using BEVACIREL 400MG/16ML INJECTION, it's crucial to inform your doctor about your complete medical history. Tell them if you have or have had conditions like high blood pressure, diabetes (high blood sugar), any stomach or bowel problems (like ulcers or holes in the intestine), or heart issues. This information helps your doctor decide if this treatment is right for you and how to manage potential risks.
  • BEVACIREL 400MG/16ML INJECTION can affect how wounds heal and increase the risk of bleeding. Therefore, it should generally not be given for 28 days before or after any surgery, including dental surgery. Always tell your doctor or dentist that you are receiving this medicine if you need any kind of procedure.
  • Like all medicines, BEVACIREL 400MG/16ML INJECTION can cause side effects. Common ones include constipation, loss of appetite, runny nose, fever, skin issues, and weight loss. More serious side effects are less common but require immediate medical attention. Report symptoms like severe headache, changes in vision, confusion, severe stomach pain, unexplained bleeding or bruising, chest pain, shortness of breath, or signs of a blood clot (like pain, swelling, or redness in an arm or leg). Regular monitoring, including checking your blood pressure and having blood tests, will be part of your treatment plan to help manage side effects and check how you are responding.

Uses of BEVACIREL 400MG/16ML INJECTION

  • Glioblastoma multiforme (a type of brain cancer)
  • Persistent, recurrent, or metastatic breast cancer
  • Metastatic cervical cancer
  • Advanced stage kidney cancer
  • Metastatic colorectal cancer
  • Advanced non-small-cell lung cancer
  • Primary liver cancer - Hepatocellular carcinoma
  • Cancers of the ovary, cervix, fallopian tube, or affecting the primary peritoneal lining

Safety Advice for BEVACIREL 400MG/16ML INJECTION
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Pregnancy

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Inform your physician before starting your treatment with BEVACIREL 400MG/16ML INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Dosage of BEVACIREL 400MG/16ML INJECTION
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  • Your healthcare provider, either a physician or a nurse, will be responsible for administering BEVACIREL 400MG/16ML INJECTION. This medication is given as an intravenous infusion, which means it is slowly delivered directly into a vein. This process ensures the medication is absorbed effectively into your bloodstream. Before the infusion begins, the injection needs to be diluted appropriately. It is crucial that once the BEVACIREL 400MG/16ML INJECTION is diluted, the infusion is started without delay. Administering the diluted solution promptly is important to maintain its stability and effectiveness. Your medical team will prepare the dose according to your specific treatment plan and monitor you during the infusion to ensure everything goes smoothly. They will explain the process and answer any questions you may have about how BEVACIREL 400MG/16ML INJECTION is given. The duration of the infusion may vary depending on the dose and your individual needs, as determined by your doctor.

How to store BEVACIREL 400MG/16ML INJECTION?
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  • Keep BEVACIREL 400MG INJ away from the reach of children and pets.
  • Store BEVACIREL 400MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of BEVACIREL 400MG/16ML INJECTION
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  • BEVACIREL 400MG/16ML INJECTION is a specialized medicine designed to treat several types of advanced cancers. It works differently from traditional chemotherapy by targeting specific substances that help cancer grow.
  • This injection acts like a smart therapy by specifically attaching to a protein called VEGF-A. Tumors often produce a lot of VEGF-A, which acts as a signal to build new blood vessels. These new vessels are like supply lines that feed the tumor with oxygen and nutrients it needs to grow and spread.
  • By binding to VEGF-A, BEVACIREL 400MG/16ML INJECTION stops this protein from signaling the body to create more blood vessels for the tumor. Effectively, it cuts off the tumor's blood supply. This lack of oxygen and nutrients starves the cancer cells, significantly slowing down the tumor's growth and progression. It can also help shrink the tumor size or prevent it from spreading to other parts of the body.

How to use BEVACIREL 400MG/16ML INJECTION
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  • Your physician or nurse will carefully administer BEVACIREL 400MG/16ML INJECTION to you as an intravenous infusion. This means the medication will be slowly dripped into a vein, typically in your arm, over a specific period. It is crucial that the infusion is prepared and given immediately after dilution by your healthcare provider. This ensures the medication's stability and effectiveness. The administration will take place in a clinical setting, such as a hospital or clinic, where you can be properly monitored throughout the infusion process. The duration of the infusion will depend on your specific treatment plan and dosage, but it is generally given over 30 to 90 minutes. Your healthcare team will closely watch for any reactions during and after the infusion. Never attempt to administer this medication yourself; it requires professional medical expertise and careful preparation.

FAQs

Is BEVACIREL 400MG/16ML INJECTION used as standalone treatment in cancers?

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BEVACIREL 400MG/16ML INJECTION is a recombinant monoclonal antibody that belongs to the immunotherapy class of cancer treatment. It can either be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.

Is it safe for women to use BEVACIREL 400MG/16ML INJECTION?

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While for women with reproductive potential subjected to BEVACIREL 400MG/16ML INJECTION, it is advised to discuss with your doctor regarding the effective birth control methods during the treatment. Also to be continued for a minimum of 6 months after the treatment course completion as this medicine may impair fertility.

Is it safe to undergo a surgery during the treatment with BEVACIREL 400MG/16ML INJECTION?

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BEVACIREL 400MG/16ML INJECTION is associated with increased risk of bleeding complications and poor wound healing. Hence it is suggested to avoid planning for surgery and maintain an interval of 28days before or after surgery.

Do the side effects of BEVACIREL 400MG/16ML INJECTION last for a chronic period?

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All the side effects that are relatively caused by BEVACIREL 400MG/16ML INJECTION occur until the drug concentration stays in the body. It is found that this medicine will be contained in our body for almost 4 months after the final dose.

How is BEVACIREL 400MG/16ML INJECTION administered?

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BEVACIREL 400MG/16ML INJECTION is given intravenously through infusion and the amount of drug will be measured based on the patient’s body weight, height and age. The first dose will be administered for 90 minutes and if well tolerated the infusion time can be reduced to 30 minutes.

Can I take BEVACIREL 400MG/16ML INJECTION if I am pregnant?

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Inform your physician before starting your treatment with BEVACIREL 400MG/16ML INJECTION in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.

Does BEVACIREL 400MG/16ML INJECTION interact with other medicines?

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It is important to inform your doctor about all the medicines you are currently taking, including prescription, over-the-counter, and herbal supplements, before starting treatment with BEVACIREL 400MG/16ML INJECTION. Your doctor will determine if there are any potential interactions.

What precautions should I take before using BEVACIREL 400MG/16ML INJECTION?

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It is vital to inform your physician before taking BEVACIREL 400MG/16ML INJECTION if you have the following conditions: Have conditions involving inflammation in the stomach (ulcer, colitis). Experience allergic reactions to BEVACIREL 400MG/16ML INJECTION or its ingredients. Have recently undergone surgery as it is associated with the risk of bleeding. Have diabetes, hypertension, or heart problems.

What is the active ingredient in BEVACIREL 400MG/16ML INJECTION?

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BEVACIREL 400MG/16ML INJECTION contains BEVACIZUMAB as the active molecule.

What is BEVACIREL 400MG/16ML INJECTION used for?

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BEVACIREL 400MG/16ML INJECTION is used to treat various types of cancer.

References

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Roche Products Limited, Electronic Medicines Compendium (EMC)

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Roche Group, U.S FDA

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Roche Group, Bevacizumab Injection, Indication

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Ratings & Review

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Generic medicines available at low cost

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(5/5)

Had a good experience when I went for purchasing medicine. Appreciate the service

Chitrang Shah

Reviewed on 07-11-2022

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(5/5)


Marketer / Manufacturer Details

RELIANCE LIFE SCIENCES

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India

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BEVACIREL 400MG/16ML INJECTION

MRP

56889.56

₹15929

72 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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