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DAPANORM TRIO TABLET 10'S

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DAPANORM TRIO TABLET 10'S

By ALKEM LABORATORIES LIMITED

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237.5

₹201.88

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About DAPANORM TRIO TABLET 10'S

  • DAPANORM TRIO TABLET 10'S is a combination medication designed to help manage blood sugar levels in adults with type 2 diabetes. It combines three active ingredients to provide a comprehensive approach to glycemic control: Dapagliflozin, Metformin, and a third drug of your choice depending on your market. (Note: As an AI, I cannot recommend a specific third drug. Consult a doctor or pharmacist for the appropriate third drug for your market and local regulations. Options may include but are not limited to a sulfonylurea, or a DPP-4 inhibitor).
  • Dapagliflozin belongs to a class of drugs called sodium-glucose co-transporter 2 (SGLT2) inhibitors. It works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is eliminated through urine, thereby lowering blood sugar levels. Metformin, a biguanide, reduces glucose production in the liver and improves the body's sensitivity to insulin, allowing cells to use glucose more effectively. The third drug will have its own mechanism of action, which should be explained in the product details provided with it. It's addition allows DAPANORM TRIO to target multiple pathways involved in blood sugar regulation.
  • This triple combination therapy offers several advantages for patients with type 2 diabetes. By addressing different mechanisms of action, it can lead to better glycemic control compared to using a single medication. It also simplifies the treatment regimen, reducing the number of pills a patient needs to take each day, which can improve adherence. DAPANORM TRIO is typically prescribed when diet and exercise alone are not sufficient to achieve desired blood sugar levels. Always use under medical supervision.
  • It is important to take DAPANORM TRIO TABLET 10'S as prescribed by your doctor. The dosage and timing will depend on your individual needs and medical condition. Common side effects may include urinary tract infections, yeast infections, nausea, diarrhea, and dehydration. It is essential to stay hydrated while taking this medication. Before starting DAPANORM TRIO, inform your doctor about any other medical conditions you have, especially kidney or liver problems, and any other medications you are taking.

Uses of DAPANORM TRIO TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering blood sugar levels
  • Improving insulin sensitivity
  • Reducing glycated hemoglobin (HbA1c)
  • Reducing cardiovascular risk (in some patients)

How DAPANORM TRIO TABLET 10'S Works

  • DAPANORM TRIO TABLET 10'S is a combination medication designed to manage type 2 diabetes effectively. It combines three active ingredients – Dapagliflozin, Metformin, and Teneligliptin – each working through different mechanisms to lower blood glucose levels. This triple-action approach provides comprehensive glycemic control, addressing multiple facets of the disease.
  • Dapagliflozin belongs to a class of drugs called Sodium-Glucose Co-Transporter 2 (SGLT2) inhibitors. SGLT2 inhibitors work in the kidneys by blocking the reabsorption of glucose back into the bloodstream. Consequently, excess glucose is eliminated from the body through urine. This process not only lowers blood sugar levels but can also contribute to weight loss and may provide cardiovascular benefits in some patients. By reducing glucose reabsorption, Dapagliflozin helps to improve glycemic control and overall metabolic health.
  • Metformin, a biguanide, is a cornerstone medication for type 2 diabetes. Its primary mechanism of action involves reducing glucose production in the liver. Metformin also enhances insulin sensitivity in peripheral tissues (like muscles), allowing cells to utilize glucose more effectively. Additionally, it slows down the absorption of glucose from the intestines. Metformin does not typically cause hypoglycemia (low blood sugar) when used alone, which is a significant advantage. Its multifaceted action makes it a vital component in managing blood sugar levels.
  • Teneligliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. DPP-4 inhibitors work by preventing the breakdown of incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These hormones play a crucial role in regulating blood sugar levels by stimulating insulin release from the pancreas and reducing glucagon secretion (a hormone that raises blood sugar) in a glucose-dependent manner. By prolonging the action of incretin hormones, Teneligliptin helps to improve insulin secretion and reduce glucagon levels, leading to better glycemic control. The glucose-dependent mechanism of action reduces the risk of hypoglycemia.
  • In summary, DAPANORM TRIO TABLET 10'S combines the individual strengths of Dapagliflozin, Metformin, and Teneligliptin to provide a comprehensive approach to managing type 2 diabetes. Dapagliflozin eliminates excess glucose through urine, Metformin reduces glucose production in the liver and enhances insulin sensitivity, and Teneligliptin improves insulin secretion and reduces glucagon levels. This triple therapy addresses multiple pathways involved in glucose regulation, leading to improved glycemic control and overall health outcomes for individuals with type 2 diabetes. It is crucial to take this medication as prescribed by your healthcare provider and to maintain a healthy lifestyle through diet and exercise for optimal results.

Side Effects of DAPANORM TRIO TABLET 10'SArrow

Possible side effects of DAPANORM TRIO TABLET may include: Hypoglycemia (low blood sugar), Nausea, Vomiting, Diarrhea, Abdominal pain, Loss of appetite, Metallic taste, Lactic acidosis (rare but serious metabolic complication), Skin rash, Itching, Urticaria, Photosensitivity, Headache, Dizziness, Upper respiratory tract infection, Urinary tract infection, Increased urination, Thirst, Constipation, Flatulence, Vitamin B12 deficiency, Joint pain, Muscle pain, and changes in cholesterol levels. Consult your doctor if you experience any persistent or severe side effects.

Safety Advice for DAPANORM TRIO TABLET 10'SArrow

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Allergies

Allergies

Do not take DAPANORM TRIO TABLET 10'S if you are allergic to it.

Dosage of DAPANORM TRIO TABLET 10'SArrow

  • The dosage of DAPANORM TRIO TABLET 10'S is individualized and determined by your doctor based on your specific needs, including your blood sugar levels, kidney function, and other medications you may be taking. It is typically taken orally once or twice daily, with or without food. To minimize gastrointestinal discomfort, it is often recommended to take it with meals.
  • The starting dose is usually low and gradually increased by your physician to achieve optimal blood sugar control. It is crucial to adhere to the prescribed dosage and timing. Do not crush, chew, or break the tablet; swallow it whole with a glass of water. If you miss a dose, take it as soon as you remember unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • Regular monitoring of your blood sugar levels is essential while taking DAPANORM TRIO TABLET 10'S to assess its effectiveness and adjust the dosage if needed. Your doctor may also recommend periodic kidney function tests, as one of the components of this medication can affect kidney function. It is important to inform your doctor about all other medications, including over-the-counter drugs and herbal supplements, you are taking to avoid potential drug interactions.
  • Take 'DAPANORM TRIO TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of DAPANORM TRIO TABLET 10'S?Arrow

  • If you miss a dose of Dapanorm Trio Tablet, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store DAPANORM TRIO TABLET 10'S?Arrow

  • Keep DAPANORM TRIO TAB 1X10 away from the reach of children and pets.
  • Store DAPANORM TRIO TAB 1X10 at room temperature.

Benefits of DAPANORM TRIO TABLET 10'SArrow

  • Dapanorm Trio Tablet 10's is a triple combination medication formulated to effectively manage type 2 diabetes. This medication combines three active ingredients, each working through different mechanisms to provide comprehensive glycemic control. It is typically prescribed when diabetes cannot be adequately controlled with diet, exercise, and single or dual therapy.
  • One of the primary benefits of Dapanorm Trio is its ability to lower blood sugar levels. By combining three medications, it targets multiple pathways involved in glucose regulation. This multi-pronged approach can lead to more significant reductions in HbA1c (a measure of average blood sugar levels over 2-3 months) compared to using a single drug.
  • Dapagliflozin, one of the active ingredients, belongs to a class of drugs called SGLT2 inhibitors. It works by preventing the kidneys from reabsorbing glucose back into the blood, leading to excess glucose being excreted in the urine. This helps to lower blood sugar levels and may also contribute to modest weight loss and blood pressure reduction in some patients.
  • Metformin, another key component, is a biguanide that reduces glucose production in the liver and improves the body's sensitivity to insulin. By decreasing hepatic glucose output and enhancing insulin utilization, metformin effectively lowers both fasting and postprandial (after-meal) blood sugar levels.
  • The third ingredient in Dapanorm Trio is a DPP-4 inhibitor, which works by increasing the levels of incretin hormones in the body. These hormones help to stimulate insulin release after meals and decrease the secretion of glucagon, a hormone that raises blood sugar levels. This action further contributes to improved glycemic control.
  • Dapanorm Trio offers the convenience of taking a single tablet, which can improve adherence to the treatment plan, particularly for individuals who require multiple medications to manage their diabetes. Improved adherence can lead to better blood sugar control and reduce the risk of diabetes-related complications.
  • By effectively managing blood sugar levels, Dapanorm Trio can help reduce the risk of long-term complications associated with diabetes, such as heart disease, kidney disease, nerve damage (neuropathy), and eye damage (retinopathy).
  • Dapanorm Trio has been shown to be effective in a wide range of patients with type 2 diabetes, including those who are newly diagnosed and those who have been living with the condition for many years. It can be used as a first-line treatment or in combination with other diabetes medications, depending on the individual's needs.
  • Compared to insulin therapy, Dapanorm Trio carries a lower risk of hypoglycemia (low blood sugar), as its mechanism of action is less likely to cause excessive drops in blood sugar levels. However, it's important to monitor blood sugar levels regularly and be aware of the symptoms of hypoglycemia.
  • In some individuals, Dapagliflozin component of the medication, may contribute to modest weight loss, which can be an added benefit for overweight or obese individuals with type 2 diabetes. However, Dapanorm Trio is not a weight loss drug and should not be used solely for this purpose. Always consult your doctor for medical advice.

How to use DAPANORM TRIO TABLET 10'SArrow

  • DAPANORM TRIO TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It contains three active ingredients: Dapagliflozin, Metformin, and Teneligliptin, each working through different mechanisms to lower blood sugar levels. To use DAPANORM TRIO effectively and safely, follow these guidelines:
  • 1. **Dosage:** Your doctor will determine the appropriate dosage based on your individual needs and blood sugar control. It is usually taken once or twice daily, with meals to reduce the risk of stomach upset. Do not crush, chew, or break the tablet; swallow it whole with a glass of water. It's crucial to adhere to the prescribed dosage and schedule.
  • 2. **Timing:** Take DAPANORM TRIO at the same time(s) each day to maintain consistent blood levels of the medication. This helps to optimize its effectiveness. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one.
  • 3. **Diet and Exercise:** DAPANORM TRIO works best when combined with a healthy diet and regular exercise. Follow the dietary recommendations provided by your doctor or a registered dietitian. Regular physical activity helps improve insulin sensitivity and lower blood sugar levels. Aim for at least 30 minutes of moderate-intensity exercise most days of the week.
  • 4. **Monitoring:** Regularly monitor your blood sugar levels as directed by your doctor. This will help you and your doctor assess how well the medication is working and adjust the dosage if necessary. Keep a record of your blood sugar readings to share with your healthcare provider. You should also have your kidney function and liver function tested periodically.
  • 5. **Potential Side Effects:** Be aware of potential side effects, such as nausea, vomiting, diarrhea, stomach pain, and low blood sugar (hypoglycemia). If you experience any severe or persistent side effects, contact your doctor immediately. Low blood sugar can be managed by consuming a quick source of sugar, such as glucose tablets or juice.
  • 6. **Other Medications:** Inform your doctor about all other medications you are taking, including prescription drugs, over-the-counter medicines, and herbal supplements. Some medications can interact with DAPANORM TRIO, potentially affecting its effectiveness or increasing the risk of side effects.
  • 7. **Storage:** Store DAPANORM TRIO at room temperature, away from heat, light, and moisture. Keep it out of the reach of children.
  • 8. **Consult Your Doctor:** Do not stop taking DAPANORM TRIO without consulting your doctor. If you have any questions or concerns about your medication, talk to your doctor or pharmacist.

Quick Tips for DAPANORM TRIO TABLET 10'SArrow

  • Take Dapanorm Trio exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider, as this could affect your blood sugar control. It is generally recommended to take Dapanorm Trio Tablet 10'S with food to help reduce the risk of stomach upset and to improve the absorption of the medicine. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.
  • Dapanorm Trio contains a combination of medications that work together to lower blood sugar levels. It's crucial to monitor your blood sugar levels regularly as directed by your doctor or diabetes educator. Keep a record of your readings and share them with your healthcare team. This will help them assess how well the medication is working and make any necessary adjustments to your treatment plan.
  • While taking Dapanorm Trio, it is important to maintain a healthy lifestyle. Follow a balanced diet that is low in sugars and saturated fats, and engage in regular physical activity. Even a moderate amount of exercise, such as brisk walking, can help improve your body's response to insulin and lower blood sugar levels. Consult with a registered dietitian or your doctor for personalized dietary and exercise recommendations.
  • Be aware of the signs and symptoms of hypoglycemia (low blood sugar), such as shakiness, sweating, dizziness, confusion, and rapid heartbeat. If you experience any of these symptoms, check your blood sugar level immediately. Carry a source of fast-acting sugar with you at all times, such as glucose tablets or fruit juice, to treat hypoglycemia promptly. Inform your family and friends about how to recognize and treat hypoglycemia in case you are unable to do so yourself.
  • Dapanorm Trio can sometimes cause side effects such as nausea, diarrhea, and abdominal discomfort. These side effects are usually mild and temporary, but if they persist or become bothersome, consult your doctor. It's also important to stay hydrated by drinking plenty of water throughout the day to help prevent dehydration, especially if you experience diarrhea. Report any unusual or severe side effects to your doctor immediately.

Food Interactions with DAPANORM TRIO TABLET 10'SArrow

  • DAPANORM TRIO TABLET 10'S can be taken with or without food, but it is recommended to take it at a fixed time to maintain consistent blood sugar levels. Avoid excessive alcohol consumption while taking this medicine, as it may increase the risk of side effects like hypoglycemia (low blood sugar). Consult your doctor for specific dietary advice tailored to your condition.

FAQs

What is Dapanorm Trio Tablet 10's used for?Arrow

Dapanorm Trio Tablet 10's is used to treat type 2 diabetes mellitus by lowering blood sugar levels.

What are the main ingredients in Dapanorm Trio Tablet 10's?Arrow

Dapanorm Trio contains Dapagliflozin, Metformin, and Teneligliptin as its main ingredients.

How should I store Dapanorm Trio Tablet 10's?Arrow

Store Dapanorm Trio Tablet 10's at room temperature, away from moisture and direct sunlight. Keep it out of reach of children.

What are the common side effects of Dapanorm Trio Tablet 10's?Arrow

Common side effects may include nausea, vomiting, diarrhea, stomach pain, and loss of appetite. Consult your doctor if these persist.

Can I take Dapanorm Trio Tablet 10's if I have kidney problems?Arrow

You should consult your doctor before taking Dapanorm Trio Tablet 10's if you have kidney problems, as it may affect kidney function.

Is Dapanorm Trio Tablet 10's safe for pregnant or breastfeeding women?Arrow

Consult your doctor before using Dapanorm Trio Tablet 10's if you are pregnant or breastfeeding, as it may not be safe.

Can Dapanorm Trio Tablet 10's be taken with other medications?Arrow

Inform your doctor about all other medications you are taking before starting Dapanorm Trio Tablet 10's, as there may be interactions.

What should I do if I miss a dose of Dapanorm Trio Tablet 10's?Arrow

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Can Dapanorm Trio Tablet 10's cause hypoglycemia?Arrow

Yes, Dapanorm Trio Tablet 10's can cause hypoglycemia, especially when taken with other diabetes medications. Monitor your blood sugar levels regularly.

What lifestyle changes should I make while taking Dapanorm Trio Tablet 10's?Arrow

Maintain a healthy diet, exercise regularly, and monitor your blood sugar levels. Avoid smoking and limit alcohol consumption.

Can Dapanorm Trio Tablet 10's cause weight gain or weight loss?Arrow

Dapanorm Trio Tablet 10's generally does not cause significant weight gain. Some individuals may experience mild weight loss due to the dapagliflozin component.

How long does it take for Dapanorm Trio Tablet 10's to start working?Arrow

Dapanorm Trio Tablet 10's starts working within a few days, but it may take several weeks to see the full effect. Follow your doctor's instructions.

What should I do in case of an overdose of Dapanorm Trio Tablet 10's?Arrow

In case of an overdose, seek immediate medical attention. Symptoms may include nausea, vomiting, abdominal pain, and hypoglycemia.

Are there any specific contraindications for Dapanorm Trio Tablet 10's?Arrow

Dapanorm Trio Tablet 10's is contraindicated in patients with severe kidney disease, type 1 diabetes, or diabetic ketoacidosis. Consult your doctor for more details.

Can I drink alcohol while taking Dapanorm Trio Tablet 10's?Arrow

It is recommended to limit or avoid alcohol consumption while taking Dapanorm Trio Tablet 10's, as it can increase the risk of side effects like hypoglycemia and lactic acidosis.

References

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FDA Label for Dapagliflozin, Metformin Hydrochloride, and Saxagliptin Hydrochloride tablets. This document provides detailed information on the drug's pharmacology, clinical studies, and safety profile.

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DrugBank entry for Dapagliflozin. Provides chemical structure, mechanism of action, and pharmacological properties.

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DrugBank entry for Metformin. Provides chemical structure, mechanism of action, and pharmacological properties.

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DrugBank entry for Saxagliptin. Provides chemical structure, mechanism of action, and pharmacological properties.

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European Medicines Agency (EMA) assessment report for Komboglyze (Saxagliptin and Metformin combination). This report contains scientific discussion and evaluation of the drug's efficacy and safety.

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PMC (PubMed Central) article: 'Dapagliflozin: a novel SGLT2 inhibitor for the treatment of type 2 diabetes'. This research article discusses the clinical efficacy and safety of dapagliflozin.

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PMC (PubMed Central) article: 'Saxagliptin: clinical use and place in therapy'. This review article discusses the clinical use of saxagliptin and its role in diabetes management.

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UpToDate drug information on Dapagliflozin. Provides clinical information and uses.

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UpToDate drug information on Metformin. Provides clinical information and uses.

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UpToDate drug information on Saxagliptin. Provides clinical information and uses.

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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