AFOGLIP M 1000MG TABLET 10'S
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AFOGLIP M 1000MG TABLET 10'S

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AFOGLIP M 1000MG TABLET 10'S

By TORRENT PHARMACEUTICALS LIMITED

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301.87

₹256.59

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Content Reviewed By:

Dr. Manoj Shah

, (MBBS)

Written By:

Ms. Priyanka Shah

, (B.Pharm)

About AFOGLIP M 1000MG TABLET 10'S

  • AFOGLIP M 1000MG TABLET 10'S is a highly effective combination medication specifically designed for the comprehensive management of Type 2 Diabetes Mellitus. This powerful oral anti-diabetic medicine plays a crucial role in helping individuals achieve optimal control over their blood sugar levels, thereby reducing the risk of serious long-term complications associated with uncontrolled diabetes. It offers a convenient and robust approach to diabetes care, making it easier for patients to adhere to their treatment plans and lead healthier lives. By combining two potent active ingredients, AFOGLIP M addresses multiple aspects of glucose regulation, providing a superior therapeutic benefit.
  • The efficacy of AFOGLIP M 1000MG TABLET stems from its dual-action formulation, which includes Metformin Hydrochloride (1000mg) and a potent gliptin component. Metformin, a cornerstone in diabetes treatment, primarily works by decreasing glucose production in the liver and improving the body's sensitivity to insulin, allowing cells to absorb more sugar from the bloodstream. It also helps to slow down sugar absorption from the intestines. The gliptin, on the other hand, belongs to the Dipeptidyl Peptidase-4 (DPP-4) inhibitor class. It enhances the body's natural ability to lower high blood sugar levels by increasing the release of insulin from the pancreas (especially after meals) and reducing the secretion of glucagon, a hormone that raises blood sugar. This synergistic action ensures more stable and effective glucose control throughout the day.
  • Choosing AFOGLIP M 1000MG TABLET means opting for enhanced glycemic control, which is vital for preventing the progression of diabetes-related health issues such as heart disease, kidney damage, nerve problems (neuropathy), and vision impairment. Its combined mechanism not only lowers blood sugar but also helps maintain it within a healthy range, improving overall metabolic health. This medication is a key component of a holistic diabetes management strategy, which should also include a balanced diet, regular physical activity, and consistent monitoring of blood glucose. Always remember to take AFOGLIP M exactly as prescribed by your healthcare provider to achieve the best possible outcomes and to ensure your safety.

Uses of AFOGLIP M 1000MG TABLET 10'S

  • Management of Type 2 Diabetes Mellitus
  • Controlling high blood sugar levels
  • Improving long-term blood sugar control (HbA1c)
  • Reducing the risk of serious diabetes complications (e.g., kidney damage, nerve problems, blindness, heart issues)
  • Used along with diet and exercise for effective blood sugar management

How AFOGLIP M 1000MG TABLET 10'S Works

  • AFOGLIP M 1000MG TABLET is a highly effective combination medication specifically designed for individuals managing Type 2 Diabetes Mellitus. This powerful tablet brings together the therapeutic benefits of two distinct classes of anti-diabetic agents: a Dipeptidyl Peptidase-4 (DPP-4) inhibitor, commonly referred to as a gliptin, and Metformin Hydrochloride. Together, these active ingredients work synergistically to provide comprehensive control over elevated blood sugar levels. The dual mechanism of action targets different pathways involved in glucose metabolism, offering a robust approach to improve glycemic control and help patients maintain a healthier life. This makes AFOGLIP M a cornerstone in many diabetes management regimens, helping to prevent the long-term complications associated with uncontrolled blood sugar.
  • The gliptin component in AFOGLIP M, a DPP-4 inhibitor, plays a crucial role in enhancing the body's natural ability to lower blood sugar. It works by targeting an enzyme called Dipeptidyl Peptidase-4 (DPP-4), which is responsible for breaking down incretin hormones, primarily Glucagon-Like Peptide-1 (GLP-1) and Glucose-Dependent Insulinotropic Polypeptide (GIP). These incretin hormones are naturally released by the gut in response to food intake and play a vital role in regulating blood glucose. By inhibiting the DPP-4 enzyme, the gliptin effectively increases the levels of active GLP-1 and GIP in the bloodstream. Higher levels of these incretins lead to a glucose-dependent increase in insulin secretion from the pancreatic beta cells, meaning insulin is released primarily when blood sugar levels are high. Simultaneously, they reduce glucagon secretion from pancreatic alpha cells, which helps decrease the liver's production of glucose. This combined action ensures better post-meal blood sugar control without significantly increasing the risk of hypoglycemia when used as monotherapy or with metformin.
  • Complementing the action of the gliptin, Metformin Hydrochloride, the second active ingredient in AFOGLIP M 1000MG TABLET, is a well-established and widely used anti-diabetic medication. Metformin primarily works by reducing the amount of glucose produced by the liver, a process known as hepatic gluconeogenesis. The liver continuously produces glucose, and in individuals with Type 2 Diabetes, this production can be excessive. Metformin effectively dampens this overproduction. Additionally, Metformin helps improve the body's sensitivity to insulin. It enhances the uptake and utilization of glucose by peripheral tissues, such as muscles and fat cells, making them more responsive to the insulin that the body produces. This means that more glucose is removed from the bloodstream and used for energy or stored, rather than circulating and causing high blood sugar. Furthermore, Metformin also modestly decreases the absorption of glucose from the gastrointestinal tract.
  • The combination of a DPP-4 inhibitor and Metformin in AFOGLIP M 1000MG TABLET offers a comprehensive and effective strategy for Type 2 Diabetes management. While the gliptin enhances glucose-dependent insulin release and suppresses glucagon, Metformin tackles excessive glucose production by the liver and improves insulin sensitivity throughout the body. This dual approach leads to better and more consistent blood sugar control throughout the day, including after meals and during fasting periods. Patients often experience improved HbA1c levels, a key indicator of long-term blood sugar control. This synergistic action not only helps in managing current blood glucose levels but also contributes significantly to reducing the risk of diabetes-related complications over time. It's important to remember that AFOGLIP M is most effective when used as part of a holistic diabetes management plan that includes a balanced diet and regular physical activity, all under the guidance of your healthcare provider.

Side Effects of AFOGLIP M 1000MG TABLET 10'SArrow

AFOGLIP M 1000mg Tablet is a medication primarily used to manage blood sugar levels in adults with type 2 diabetes. While generally well-tolerated, it's important to be aware of potential side effects, both common and rare. Common side effects may include: Nausea, vomiting, diarrhea, stomach pain, loss of appetite, and a metallic taste in the mouth. Some individuals might experience headaches, cold-like symptoms (nasopharyngitis), or constipation. Less common but more serious side effects can include: Low blood sugar (hypoglycemia), especially if used with other diabetes medications like sulfonylureas or insulin. Rarely, it may cause skin rashes or other allergic reactions. Very rare but serious side effects to watch out for are: Lactic acidosis (a severe build-up of lactic acid in the blood, symptoms include extreme tiredness, muscle pain, difficulty breathing, and stomach discomfort – seek immediate medical attention), inflammation of the pancreas (pancreatitis), and vitamin B12 deficiency with long-term use. Always consult your doctor if any side effect persists or worsens, or if you experience any severe or unusual reactions.

Safety Advice for AFOGLIP M 1000MG TABLET 10'SArrow

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Allergies

Consult a Doctor

If you have a known allergy to any ingredient in AFOGLIP M 1000MG TABLET 10'S, consult your doctor before use.

Dosage of AFOGLIP M 1000MG TABLET 10'SArrow

  • AFOGLIP M 1000MG TABLET 10'S is a crucial medication primarily prescribed for the management of Type 2 Diabetes Mellitus in adults. This combination drug, typically containing Vildagliptin and Metformin Hydrochloride, works synergistically to help control high blood sugar levels. Vildagliptin belongs to the class of DPP-4 inhibitors, enhancing the body's natural ability to lower elevated blood glucose, while Metformin, a biguanide, reduces glucose production by the liver and improves insulin sensitivity.
  • The recommended dosage for AFOGLIP M 1000MG TABLET 10'S is highly individualized and determined by your healthcare provider based on your specific medical condition, current blood sugar control, and response to treatment. It is imperative to adhere strictly to your physician's instructions. Generally, this medication is taken orally, often once or twice daily, ideally with meals to minimize potential gastrointestinal side effects such as nausea or stomach upset, which are more common with Metformin.
  • For optimal effectiveness and safety, do not alter your dosage or stop taking AFOGLIP M 1000MG TABLET 10'S without consulting your doctor. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In such cases, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one. Regular monitoring of your blood glucose levels, along with periodic kidney function tests, is essential while on this medication, especially given Metformin's implications for kidney health. Always discuss any concerns or side effects with your doctor promptly.
  • This medication is an integral part of a comprehensive diabetes management plan, which should also include a balanced diet and regular physical activity. Understanding and following your prescribed dosage, coupled with lifestyle modifications, is key to effectively managing Type 2 Diabetes and preventing long-term complications.
  • Take 'AFOGLIP M 1000MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of AFOGLIP M 1000MG TABLET 10'S?Arrow

  • If you miss a dose of AFOGLIP M 1000MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. Always consult your doctor or pharmacist if you are unsure or have any questions.

How to store AFOGLIP M 1000MG TABLET 10'S?Arrow

  • Keep AFOGLIP M 1000MG TAB 1X15 away from the reach of children and pets.
  • Store AFOGLIP M 1000MG TAB 1X15 at room temperature.

Benefits of AFOGLIP M 1000MG TABLET 10'SArrow

  • AFOGLIP M 1000MG TABLET is a powerful and effective medication specifically designed for the comprehensive management of Type 2 Diabetes Mellitus. It combines two highly effective and well-researched active ingredients, a gliptin (e.g., Teneligliptin or Sitagliptin, depending on the specific "AFOGLIP" compound) and Metformin Hydrochloride at a robust 1000mg dose. This dual-action approach targets multiple pathways involved in blood sugar regulation, offering superior glycemic control compared to single-agent therapies. For individuals living with Type 2 Diabetes, maintaining optimal blood sugar levels is paramount to preventing long-term complications, and AFOGLIP M provides a robust solution to achieve this critical goal. Its formulation is tailored to simplify your daily diabetes management routine, making it a convenient and reliable choice.
  • The primary benefit of AFOGLIP M lies in its synergistic mechanism of action. Metformin, a cornerstone of diabetes therapy, primarily works by reducing the amount of glucose produced by the liver, enhancing the body's sensitivity to insulin, and slowing down the absorption of sugar from the intestines. This leads to a significant reduction in fasting blood glucose levels. Complementing this, the gliptin component belongs to the DPP-4 inhibitor class. It works by increasing the levels of natural hormones called incretins (GLP-1 and GIP) in the body. These incretins stimulate the pancreas to release more insulin when blood sugar levels are high and also reduce the amount of glucose produced by the liver, particularly after meals. This glucose-dependent action is key, meaning it primarily acts when blood sugar is elevated, leading to a more physiological response. Together, these actions result in a profound reduction in both fasting and post-meal blood sugar levels, significantly improving HbA1c, a key indicator of long-term blood sugar control.
  • Beyond its efficacy, AFOGLIP M offers several patient-centric advantages. A significant benefit is the reduced risk of hypoglycemia (low blood sugar) compared to some older classes of diabetes medications like sulfonylureas, especially due to the glucose-dependent action of the gliptin. This provides greater safety and peace of mind for patients. Furthermore, while many diabetes medications can cause weight gain, Metformin is often associated with modest weight loss or weight neutrality, and gliptins are generally weight-neutral, making AFOGLIP M a favorable option for patients concerned about weight management. The convenience of a single tablet combining two powerful agents promotes better adherence to treatment, which is vital for effective long-term diabetes management. By effectively controlling blood sugar, AFOGLIP M also plays a crucial role in mitigating the risk of serious diabetes-related complications affecting the heart, kidneys, eyes, and nerves, thereby improving overall quality of life and longevity. Its established safety profile and comprehensive benefits make it a trusted choice for managing Type 2 Diabetes.

How to use AFOGLIP M 1000MG TABLET 10'SArrow

  • AFOGLIP M 1000MG TABLET 10'S is a powerful medication specifically designed to help manage Type 2 Diabetes Mellitus. It is typically a combination of two active ingredients, working synergistically to control high blood sugar levels. For optimal results and safety, it's crucial to follow your doctor's instructions meticulously. This comprehensive guide will help you understand how to use AFOGLIP M effectively. Always take AFOGLIP M 1000MG TABLET exactly as prescribed by your healthcare provider. The dosage and frequency are tailored to your specific condition, blood sugar levels, and response to treatment. It is generally recommended to take this tablet with meals. Taking it with food helps to minimize potential gastrointestinal side effects such as nausea, vomiting, or stomach upset, which are sometimes associated with one of its components. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can alter the medication's release and effectiveness. Consistency is key; try to take your dose at the same time each day to maintain stable blood sugar levels.
  • If you happen to miss a dose, take it as soon as you remember, provided it's not almost time for your next scheduled dose. In such a case, skip the missed dose and continue with your regular dosing schedule. Never take a double dose to compensate for a missed one, as this can increase the risk of side effects. Regular monitoring of your blood sugar levels is vital while on AFOGLIP M. Your doctor will advise you on how often to check your levels and what targets to aim for. Remember, medication is just one part of diabetes management; a healthy diet, regular exercise, and maintaining a healthy weight are equally important and will significantly enhance the effectiveness of AFOGLIP M 1000MG TABLET. Discuss any existing medical conditions or other medications you are taking with your doctor before starting AFOGLIP M. This includes over-the-counter drugs, herbal supplements, and vitamins, as they may interact with the medication. Stay well-hydrated throughout the day, especially if experiencing any gastrointestinal discomfort. Do not stop taking AFOGLIP M 1000MG TABLET abruptly without consulting your doctor, even if you feel better, as stopping suddenly can lead to a rise in blood sugar levels.

Quick Tips for AFOGLIP M 1000MG TABLET 10'SArrow

  • To effectively manage Type 2 Diabetes, always take AFOGLIP M 1000MG TABLET exactly as prescribed by your doctor. Establishing a consistent daily routine, perhaps with a specific meal, is crucial for maintaining stable blood glucose levels and maximizing the medication's benefits. Missing doses can compromise treatment efficacy, while unauthorized adjustments can lead to adverse effects. Regular and disciplined intake ensures optimal blood sugar control, helping to prevent fluctuations and reduce the long-term risk of diabetes-related complications.
  • It is highly recommended to consume AFOGLIP M 1000MG TABLET alongside your meals, especially your main meals. This practice significantly helps to alleviate common gastrointestinal side effects often associated with Metformin, such as nausea, diarrhea, stomach upset, or a metallic taste. Starting with a lower dose and gradually increasing it as directed by your healthcare provider can also improve tolerance. Taking the tablet with food ensures better absorption and a more comfortable experience, allowing for seamless integration into your daily routine.
  • Maintaining adequate hydration is essential while on AFOGLIP M 1000MG TABLET. Drinking plenty of water throughout the day supports your kidneys in efficiently processing the medication and helps mitigate potential side effects, particularly if you experience any digestive upset. Good hydration also contributes to overall metabolic health, which is critical for individuals managing diabetes. Make a conscious effort to regularly sip water, ensuring your body functions optimally and remains well-supported.
  • AFOGLIP M 1000MG TABLET works best when complemented by a healthy lifestyle. This includes adopting a balanced diet low in processed sugars and refined carbohydrates, and engaging in regular physical activity. Even moderate exercise, such as brisk walking or cycling, can significantly improve insulin sensitivity and aid in blood sugar management. Consult with a dietitian or diabetes educator to develop a personalized nutrition and exercise plan that aligns with your medication and health objectives, forming a powerful synergy for effective diabetes management.
  • Consistent monitoring of your blood glucose levels is paramount to assess the effectiveness of AFOGLIP M 1000MG TABLET and to guide your doctor in making necessary treatment adjustments. Be vigilant for symptoms of hypoglycemia (low blood sugar), such as lightheadedness, excessive sweating, confusion, or tremors, especially if you skip meals or exert yourself intensely. Pay attention to any persistent or severe gastrointestinal discomfort. Always report unusual symptoms or concerning side effects to your healthcare provider promptly and never alter your dosage without explicit medical guidance.

Food Interactions with AFOGLIP M 1000MG TABLET 10'SArrow

  • AFOGLIP M 1000MG TABLET 10'S may interact with alcohol. Consuming excessive amounts of alcohol can potentially increase the risk of a serious condition called lactic acidosis, which can be life-threatening.

FAQs

What is AFOGLIP M 1000mg Tablet used for?Arrow

AFOGLIP M 1000mg Tablet is primarily used to treat Type 2 Diabetes Mellitus. It helps to control high blood sugar levels when diet and exercise alone are not enough.

What are the active ingredients in AFOGLIP M 1000mg Tablet?Arrow

AFOGLIP M 1000mg Tablet contains two active ingredients: Teneligliptin and Metformin Hydrochloride. Metformin is present in a strength of 1000mg, and Teneligliptin is typically 20mg.

How does AFOGLIP M 1000mg Tablet work to control blood sugar?Arrow

This tablet works through a dual mechanism. Teneligliptin is a DPP-4 inhibitor that increases the release of insulin from the pancreas and reduces hormones that raise blood sugar. Metformin is a biguanide that reduces glucose production in the liver, decreases glucose absorption from the intestines, and improves insulin sensitivity.

What are the common side effects of AFOGLIP M 1000mg Tablet?Arrow

Common side effects may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste in the mouth, and headache. These usually subside as your body adjusts to the medication.

Are there any serious side effects I should be aware of?Arrow

Serious but rare side effects can include lactic acidosis (a build-up of lactic acid in the blood, more common with Metformin), pancreatitis (inflammation of the pancreas), severe allergic reactions, and kidney problems. Seek immediate medical attention if you experience symptoms like severe stomach pain, persistent vomiting, unexplained muscle pain, or difficulty breathing.

How should I take AFOGLIP M 1000mg Tablet?Arrow

You should take AFOGLIP M 1000mg Tablet exactly as prescribed by your doctor, usually with meals to reduce stomach upset. Do not crush, chew, or break the tablet; swallow it whole.

What should I do if I miss a dose of AFOGLIP M 1000mg Tablet?Arrow

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one.

Can I stop taking AFOGLIP M 1000mg Tablet once my blood sugar levels are normal?Arrow

No, you should not stop taking AFOGLIP M 1000mg Tablet without consulting your doctor. Stopping the medication abruptly can lead to a rapid increase in blood sugar levels, which can be dangerous. Diabetes is a chronic condition that requires continuous management.

Is AFOGLIP M 1000mg Tablet safe during pregnancy or breastfeeding?Arrow

AFOGLIP M 1000mg Tablet is generally not recommended during pregnancy or breastfeeding unless specifically advised by a doctor after weighing the potential benefits and risks. Always consult your healthcare provider if you are pregnant, planning to conceive, or breastfeeding.

Can I drink alcohol while taking AFOGLIP M 1000mg Tablet?Arrow

It is generally advised to limit or avoid alcohol consumption while taking AFOGLIP M, especially due to the Metformin component. Alcohol can increase the risk of lactic acidosis and may also affect blood sugar levels, leading to hypoglycemia (low blood sugar).

How should AFOGLIP M 1000mg Tablet be stored?Arrow

Store AFOGLIP M 1000mg Tablet at room temperature, away from direct light and moisture. Keep it out of reach of children and pets. Do not use the medication after its expiry date.

What are the symptoms of an overdose of AFOGLIP M 1000mg Tablet?Arrow

An overdose can lead to severe hypoglycemia (dizziness, confusion, sweating, tremors, rapid heartbeat) or lactic acidosis (severe stomach pain, muscle pain, difficulty breathing, unusual tiredness). Seek emergency medical attention immediately if you suspect an overdose.

Can AFOGLIP M 1000mg Tablet cause weight gain or loss?Arrow

Metformin, one of the components, is often associated with weight stability or modest weight loss, unlike some other antidiabetic medications that may cause weight gain. Teneligliptin is generally weight-neutral.

Are there other brands that contain Teneligliptin and Metformin 1000mg?Arrow

Yes, there are several other brands that contain the combination of Teneligliptin and Metformin, though the Metformin strength might vary. Examples include Ziten-M, Teneli-M, Tenglyn M, among others. Always consult your doctor or pharmacist before switching brands.

Does AFOGLIP M 1000mg Tablet affect kidney function?Arrow

Metformin is primarily cleared by the kidneys. If you have impaired kidney function, your doctor may need to adjust the dose or choose an alternative medication, as there's an increased risk of lactic acidosis. Regular kidney function tests may be required while on this medication.

Does AFOGLIP M 1000mg Tablet cause hypoglycemia (low blood sugar)?Arrow

While Metformin and Teneligliptin generally have a low risk of causing hypoglycemia when used alone, the risk can increase if taken with other antidiabetic medications like insulin or sulfonylureas. It's important to monitor your blood sugar levels regularly.

References

Book Icon

Teneligliptin: a novel DPP-4 inhibitor for the treatment of type 2 diabetes mellitus.

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Metformin: An Old Drug, New Insights.

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Efficacy and safety of teneligliptin in combination with metformin in patients with type 2 diabetes mellitus: A meta-analysis.

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Pharmacokinetics, pharmacodynamics, and clinical efficacy of teneligliptin.

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Metformin: A Review of Its Molecular Mechanisms and Clinical Applications.

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