AMARYL M1 TABLET 20'S
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AMARYL M1 TABLET 20'SAMARYL M1 TABLET 20'SAMARYL M1 TABLET 20'S
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AMARYL M1 TABLET 20'S

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AMARYL M1 TABLET 20'S

By SANOFI INDIA LIMITED

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302.97

₹257.52

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Product DetailsArrow

Content Reviewed By:

Dr. Manoj Shah

, (MBBS)

Written By:

Ms. Priyanka Shah

, (B.Pharm)

About AMARYL M1 TABLET 20'S

  • Amaryl M1 Tablet is a combination anti-diabetic medicine containing glimepiride 1 mg and metformin hydrochloride 500 mg (sustained release), formulated to help manage blood sugar in people with type 2 diabetes. It is a widely used two-in-one diabetes tablet for people whose sugar is not controlled by a single medicine.
  • Amaryl M1 combines two active ingredients that lower blood sugar through different pathways. Glimepiride belongs to a class of drugs called sulfonylureas, which stimulate the pancreas to release more insulin — the hormone that helps glucose (sugar) move from the blood into cells for energy. Metformin is a biguanide that works by decreasing glucose production in the liver and improving the body's sensitivity to insulin. The metformin component is a sustained-release form, which releases the drug gradually. This dual action helps lower blood sugar more effectively than either drug alone.
  • Amaryl M1 is typically prescribed when diet and exercise alone are not enough to control blood sugar. It works best when taken consistently as directed by your healthcare provider, usually with meals to reduce the risk of stomach upset, and the dose is individualised to your blood sugar levels and response to treatment. Regular monitoring of blood sugar is crucial while taking it, both to confirm good glycaemic control and to detect potential side effects such as low blood sugar (hypoglycaemia), which can occur with the glimepiride component.
  • Amaryl M1 offers a comprehensive approach to managing type 2 diabetes by addressing multiple pathways involved in blood sugar regulation. Alongside the medicine, lifestyle changes — following a balanced diet, being physically active, and maintaining a healthy weight — are essential to maximise the benefit and improve overall health. Tell your doctor about kidney or liver problems and any other medicines you take, as these can affect how metformin and glimepiride are handled.
  • This tablet helps improve glycaemic control and overall well-being for people living with type 2 diabetes. Always consult your doctor for personalised advice and diabetes management, and seek prompt help if you notice warning signs of low blood sugar such as sweating, trembling, confusion, or palpitations.
  • Generic alternative: a generic medicine has the same active composition as the branded product — for Amaryl M1 Tablet 20's that is Metformin Hydrochloride 500 MG Sustained Release+glimepiride 1 MG. On Medkart you can compare generic options by composition and see the price difference before you buy; the molecule, strength and dosage form match. Always consult your doctor or pharmacist before switching.

Uses of AMARYL M1 TABLET 20'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving blood sugar control
  • Used in conjunction with diet and exercise
  • Management of type 2 diabetes in adults

How AMARYL M1 TABLET 20'S Works

  • AMARYL M1 Tablet 20's is a combination medication designed to manage type 2 diabetes mellitus effectively. It combines two active ingredients: glimepiride and metformin. Each component works through distinct mechanisms to lower blood glucose levels and improve overall glycemic control.
  • Glimepiride belongs to a class of drugs called sulfonylureas. It primarily works by stimulating the beta cells in the pancreas to release more insulin. Insulin is a hormone that helps glucose (sugar) move from the bloodstream into cells, where it can be used for energy. By increasing insulin secretion, glimepiride helps lower blood sugar levels, particularly after meals.
  • Metformin, on the other hand, is a biguanide. It works through several mechanisms. First, it reduces the amount of glucose produced by the liver. The liver can sometimes release excessive glucose into the bloodstream, especially in individuals with type 2 diabetes. Metformin helps suppress this process. Second, metformin improves insulin sensitivity in the body's tissues, such as muscle and fat. This means that the cells become more responsive to insulin, allowing them to take up glucose more effectively. Third, metformin slows down the absorption of glucose from the intestines after a meal.
  • By combining glimepiride and metformin, AMARYL M1 Tablet 20's addresses multiple aspects of type 2 diabetes. Glimepiride helps increase insulin secretion, while metformin reduces glucose production by the liver, enhances insulin sensitivity, and reduces glucose absorption. This synergistic effect provides better blood sugar control compared to using either medication alone. It is generally prescribed when diet and exercise alone are not sufficient to manage blood sugar levels effectively.
  • It's important to note that AMARYL M1 Tablet 20's should be used as part of a comprehensive diabetes management plan, which includes a healthy diet, regular exercise, and regular monitoring of blood glucose levels. Patients should follow their doctor's instructions carefully and be aware of potential side effects and interactions with other medications.

Side Effects of AMARYL M1 TABLET 20'SArrow

The most common side effects of Amaryl M1 Tablet are hypoglycemia (low blood sugar level), nausea, diarrhea, altered taste, and stomach pain. Other possible side effects include: Headache, Dizziness, Vomiting, Weakness, Visual disturbances, Liver problems (such as jaundice), Skin reactions (rash, itching, hives), Decreased blood cell counts (anemia, leukopenia, thrombocytopenia), Allergic reactions, Weight gain, Edema (swelling), Increased liver enzymes.

Safety Advice for AMARYL M1 TABLET 20'SArrow

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Allergies

Allergies

Consult your Doctor

Dosage of AMARYL M1 TABLET 20'SArrow

  • The dosage of AMARYL M1 TABLET 20'S is highly individualized and should be determined by your physician based on your specific metabolic needs, blood glucose monitoring results, and overall health condition. Generally, the initial recommended dose is one tablet daily, usually taken with the first main meal of the day to minimize the risk of hypoglycemia.
  • The dosage may be gradually increased by your doctor, typically in increments of 1 mg of glimepiride, at intervals of one to two weeks, based on your blood glucose response. The maximum recommended daily dose of glimepiride is 8 mg, and the maximum recommended daily dose of metformin is 2000mg. However, exceeding these limits does not necessarily translate to improved glycemic control and may increase the risk of side effects.
  • It is crucial to adhere to the prescribed dosage and timing of AMARYL M1 TABLET 20'S. Missing doses or taking the medication at irregular intervals can lead to fluctuations in blood glucose levels, potentially causing hyperglycemia or hypoglycemia. If you miss a dose, do not double the next dose to compensate; instead, consult your doctor for guidance.
  • Regular monitoring of blood glucose levels is essential during treatment with AMARYL M1 TABLET 20'S to assess the medication's effectiveness and adjust the dosage accordingly. Your doctor may also recommend periodic monitoring of kidney function, liver function, and hematologic parameters, especially during long-term use.
  • Factors such as changes in diet, exercise, or other medications can affect your blood glucose control and may necessitate adjustments in the dosage of AMARYL M1 TABLET 20'S. Always inform your doctor about any such changes to ensure optimal management of your diabetes.
  • Take 'AMARYL M1 TABLET 20'S' only as per the prescription by your physician only

What if I miss my dose of AMARYL M1 TABLET 20'S?Arrow

  • If you miss a dose of Amaryl M1 Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store AMARYL M1 TABLET 20'S?Arrow

  • Keep AMARYL M 1MG TAB 1X20 away from the reach of children and pets.
  • Store AMARYL M 1MG TAB 1X20 at room temperature.

Benefits of AMARYL M1 TABLET 20'SArrow

  • AMARYL M1 TABLET 20'S is a combination medication designed to effectively manage type 2 diabetes by controlling blood sugar levels. Its dual-action formula combines two powerful active ingredients, working synergistically to address different aspects of glucose regulation. This comprehensive approach helps individuals achieve and maintain optimal glycemic control, reducing the risk of diabetes-related complications.
  • One of the primary benefits of AMARYL M1 TABLET 20'S is its ability to stimulate insulin release from the pancreas. This is particularly beneficial for individuals whose bodies are not producing enough insulin to effectively manage blood sugar levels. By promoting insulin secretion, the medication helps lower post-meal glucose spikes and maintain a more consistent blood sugar profile throughout the day.
  • In addition to stimulating insulin release, AMARYL M1 TABLET 20'S also enhances the body's sensitivity to insulin. This means that the insulin produced, whether naturally or with the help of medication, can be utilized more effectively by the cells to absorb glucose from the bloodstream. This improved insulin sensitivity helps lower blood sugar levels and reduces insulin resistance, a common problem in individuals with type 2 diabetes.
  • AMARYL M1 TABLET 20'S also helps to decrease the amount of glucose produced by the liver. The liver can sometimes overproduce glucose, especially during periods of fasting or between meals, contributing to elevated blood sugar levels. By inhibiting this process, the medication helps prevent excessive glucose release and maintain stable blood sugar levels.
  • By effectively managing blood sugar levels, AMARYL M1 TABLET 20'S plays a crucial role in reducing the risk of long-term complications associated with diabetes. These complications can include cardiovascular disease, nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and foot problems. Maintaining optimal glycemic control with AMARYL M1 TABLET 20'S can significantly improve overall health and quality of life for individuals with type 2 diabetes.
  • AMARYL M1 TABLET 20'S offers the convenience of a single tablet combining two medications, simplifying the treatment regimen and potentially improving adherence. This can be especially beneficial for individuals who are already taking multiple medications for other conditions.
  • AMARYL M1 TABLET 20'S, when used as part of a comprehensive diabetes management plan that includes diet, exercise, and regular monitoring, can empower individuals to take control of their health and live a more active and fulfilling life. It is crucial to take the medication as prescribed by a healthcare professional and to attend regular check-ups to monitor blood sugar levels and overall health.

How to use AMARYL M1 TABLET 20'SArrow

  • AMARYL M1 Tablet 20'S should be taken orally, usually once daily, preferably with your first main meal of the day to minimize the risk of stomach upset and to optimize blood sugar control throughout the day. It is crucial to swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released and potentially lead to unwanted side effects or decreased effectiveness.
  • Your doctor will determine the appropriate dosage based on your individual needs, blood sugar levels, and response to treatment. It is essential to follow your doctor’s instructions precisely and to not adjust the dosage on your own. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • Consistent daily use of AMARYL M1 is vital for optimal blood sugar control. Combine the medication with a healthy diet and regular exercise for the best results. Monitor your blood sugar levels regularly as directed by your doctor and keep them informed of any changes or concerns. Store the tablets in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children.
  • Be aware of potential side effects, such as hypoglycemia (low blood sugar), and learn to recognize the symptoms (e.g., sweating, shaking, dizziness, confusion). If you experience these symptoms, consume a fast-acting source of sugar, such as glucose tablets or fruit juice, and seek medical attention if necessary. Inform your doctor about any other medications you are taking, as they may interact with AMARYL M1. Regular follow-up appointments with your doctor are necessary to monitor your progress and make any necessary adjustments to your treatment plan.

Quick Tips for AMARYL M1 TABLET 20'SArrow

  • Take AMARYL M1 TABLET 20'S as prescribed by your doctor, usually once daily. It's best to take it with your first main meal to help prevent stomach upset and regulate blood sugar levels effectively throughout the day. Consistency is key for optimal results.
  • Monitor your blood sugar levels regularly as advised by your healthcare provider. AMARYL M1 helps control blood sugar, but regular monitoring is essential to ensure the medication is working correctly and to make any necessary adjustments to your diet or exercise routine. Keep a log of your readings to share with your doctor.
  • Follow a balanced diet and exercise regularly while taking AMARYL M1 TABLET 20'S. This medication works best when combined with a healthy lifestyle. Focus on incorporating whole grains, lean proteins, and plenty of fruits and vegetables into your diet. Aim for at least 30 minutes of moderate-intensity exercise most days of the week.
  • Be aware of the symptoms of hypoglycemia (low blood sugar) such as shakiness, sweating, dizziness, and confusion. Carry a source of fast-acting sugar with you, such as glucose tablets or fruit juice, in case your blood sugar drops too low. Consult your doctor about how to manage hypoglycemic episodes effectively.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking before starting AMARYL M1 TABLET 20'S. This will help prevent potential drug interactions that could affect the medication's effectiveness or increase the risk of side effects. Also, make sure your doctor knows about any existing medical conditions you have.

Food Interactions with AMARYL M1 TABLET 20'SArrow

  • It is advisable to take AMARYL M1 TABLET 20'S with or immediately after your first main meal of the day to prevent stomach upset.
  • Avoid skipping meals while taking this medication. If you do skip a meal, it's important to take the medicine with your next meal to maintain consistent blood sugar levels.
  • Be cautious about consuming excessive alcohol while taking AMARYL M1 TABLET 20'S, as it can increase the risk of hypoglycemia (low blood sugar).
  • Inform your doctor about your dietary habits, especially if you are on a special diet.

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FAQs

What is Amaryl M1 Tablet 20's?Arrow

Amaryl M1 Tablet 20's is a medication used to treat type 2 diabetes. It contains two medicines: Glimepiride and Metformin.

What is Amaryl M1 Tablet 20's used for?Arrow

Amaryl M1 Tablet 20's is used to control high blood sugar levels in people with type 2 diabetes.

How does Amaryl M1 Tablet 20's work?Arrow

Amaryl M1 Tablet 20's works in two ways: Glimepiride increases the amount of insulin that the pancreas releases, and Metformin makes your body more sensitive to insulin and reduces the amount of glucose being made by the liver.

What are the common side effects of Amaryl M1 Tablet 20's?Arrow

Common side effects of Amaryl M1 Tablet 20's include nausea, vomiting, diarrhea, and stomach pain.

How should I take Amaryl M1 Tablet 20's?Arrow

Take Amaryl M1 Tablet 20's exactly as prescribed by your doctor. It is usually taken once daily with food.

Are there any serious side effects of Amaryl M1 Tablet 20's?Arrow

Serious side effects of Amaryl M1 Tablet 20's are rare, but can include low blood sugar (hypoglycemia), liver problems, and lactic acidosis.

What happens if I miss a dose of Amaryl M1 Tablet 20's?Arrow

If you miss a dose of Amaryl M1 Tablet 20's, take it as soon as you remember. If it is close to your next dose, skip the missed dose and take your next dose as normal. Do not take two doses at the same time.

Can Amaryl M1 Tablet 20's interact with other medications?Arrow

Amaryl M1 Tablet 20's can interact with many other medications, so it is important to tell your doctor about all the medicines you are taking.

How should I store Amaryl M1 Tablet 20's?Arrow

Store Amaryl M1 Tablet 20's at room temperature, away from heat and moisture.

Is it safe to take Amaryl M1 Tablet 20's if I am pregnant?Arrow

Talk to your doctor before taking Amaryl M1 Tablet 20's if you are pregnant or planning to become pregnant.

Is it safe to take Amaryl M1 Tablet 20's while breastfeeding?Arrow

Talk to your doctor before taking Amaryl M1 Tablet 20's if you are breastfeeding.

What are other brands of Metformin?Arrow

Other brands of Metformin include Glucophage, Glucophage XR, Fortamet, and Riomet.

What are other brands of Glimepiride?Arrow

Other brands of Glimepiride include Amaryl.

Does Amaryl M1 Tablet 20's cause weight gain?Arrow

Amaryl M1 Tablet 20's can cause weight gain in some people. Talk to your doctor if you are concerned about this.

How long will I need to take Amaryl M1 Tablet 20's?Arrow

How long you need to take Amaryl M1 Tablet 20's will be determined by your doctor. Most people with type 2 diabetes need to take it for life.

What is the composition of Amaryl M1 Tablet 20's?Arrow

Amaryl M1 Tablet 20's contains Glimepiride 1 MG + Metformin Hydrochloride 500 MG Sustained Release. It is a sulfonylurea antidiabetic; and biguanide antidiabetic.

What are the side effects of Amaryl M1 Tablet 20's?Arrow

Commonly reported side effects of Amaryl M1 Tablet 20's include hypoglycaemia (low blood sugar), weight gain, nausea, headache, dizziness; and diarrhoea, nausea, abdominal discomfort, metallic taste, loss of appetite — often improve with time or when taken with food. Not everyone gets side effects. Tell your doctor or pharmacist if any effect persists or worries you.

What is the price of Amaryl M1 Tablet 20's?Arrow

Amaryl M1 Tablet 20's is listed at Rs. 257.52 on Medkart. Prices can change — check the product page for the current price and pack size.

What precautions should be taken with Amaryl M1 Tablet 20's?Arrow

Hypoglycaemia can be prolonged and serious, especially in the elderly, with kidney impairment, missed meals or alcohol; and Rare but serious risk of lactic acidosis, particularly with kidney impairment, dehydration, acute illness or excess alcohol. Tell your doctor about all other medicines you take before starting Amaryl M1 Tablet 20's.

What is the correct dosage of Amaryl M1 Tablet 20's?Arrow

The dose of Amaryl M1 Tablet 20's depends on your condition, age, weight and other medicines you take, so it must be decided by your doctor. Follow the dose and duration on your prescription and do not change it on your own.

Is there a generic substitute for Amaryl M1 Tablet 20's?Arrow

A generic medicine is one with the same active composition as the branded product — for Amaryl M1 Tablet 20's that is Glimepiride 1 MG + Metformin Hydrochloride 500 MG Sustained Release. Medkart lists generic options by composition so you can compare. Ask your doctor or pharmacist before switching from Amaryl M1 Tablet 20's.

Is Amaryl M1 Tablet 20's a prescription medicine?Arrow

Yes. Amaryl M1 Tablet 20's requires a valid doctor's prescription.

Who is the manufacturer of Amaryl M1 Tablet 20's?Arrow

Amaryl M1 Tablet 20's is manufactured by Sanofi India Limited.

What is the dosage form of Amaryl M1 Tablet 20's?Arrow

Amaryl M1 Tablet 20's is supplied as a tablet and is taken by the oral route.

What are the benefits of Amaryl M1 Tablet 20's?Arrow

Amaryl M1 Tablet 20's contains Glimepiride 1 MG + Metformin Hydrochloride 500 MG Sustained Release. It is used for management of type 2 diabetes mellitus alongside diet and exercise, alone or with other antidiabetic medicines; and first-line management of type 2 diabetes mellitus, usually alongside diet and exercise. The benefit you get depends on the condition your doctor prescribed Amaryl M1 Tablet 20's for.

Is Amaryl M1 Tablet 20's safe to take daily?Arrow

Whether Amaryl M1 Tablet 20's can be taken daily, and for how long, depends on your condition and must be decided by your doctor. Do not start, extend or repeat a course of Amaryl M1 Tablet 20's on your own.

When should Amaryl M1 Tablet 20's be taken — morning or night?Arrow

The timing of Amaryl M1 Tablet 20's depends on the dose your doctor prescribes and on the other medicines you take. Follow the timing on your prescription or ask your pharmacist.

Can I take Amaryl M1 Tablet 20's without a doctor's consultation?Arrow

No. Amaryl M1 Tablet 20's is a prescription medicine and should only be taken on a doctor's advice.

Can Amaryl M1 Tablet 20's be taken during pregnancy or breastfeeding?Arrow

Do not take Amaryl M1 Tablet 20's during pregnancy or while breastfeeding without asking your doctor. Safety depends on the medicine, the stage of pregnancy and your own health.

Can I drink alcohol while taking Amaryl M1 Tablet 20's?Arrow

Check with your doctor before drinking alcohol while taking Amaryl M1 Tablet 20's. Alcohol can add to side effects such as drowsiness and can affect how some medicines work.

How should Amaryl M1 Tablet 20's be stored?Arrow

Store Amaryl M1 Tablet 20's in its original pack, below 25°C unless the pack states otherwise, away from direct sunlight and moisture, and out of the reach of children. Do not use it after the expiry date on the pack.

References

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FDA label for Amaryl (glimepiride). This document provides detailed information about the drug's pharmacology, clinical studies, indications, contraindications, warnings, precautions, adverse reactions, and dosage and administration. While this specifically pertains to Amaryl (glimepiride), it's a relevant source since AMARYL M1 contains glimepiride.

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DrugBank entry for Glimepiride. This provides comprehensive information on glimepiride, including its mechanism of action, pharmacokinetics, metabolism, and drug interactions. As glimepiride is a component of AMARYL M1, this is a relevant technical reference.

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Efficacy and safety of metformin versus other oral hypoglycemic agents in treating type 2 diabetes mellitus: A network meta-analysis. Provides insight on metformin's efficacy and safety in comparison to other oral hypoglycemic agents. AMARYL M1 contains metformin. [PMC9184040]

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DrugBank entry for Metformin. This page provides detailed information about metformin's mechanism of action, pharmacokinetics, metabolism, and drug interactions. Since AMARYL M1 contains metformin, this is an important technical reference.

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A Review of Dual Combination Therapies in Management of Type 2 Diabetes. This article reviews dual combination therapies used in type 2 diabetes management, including combinations involving glimepiride and metformin. [PMC7309727]

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European Medicines Agency (EMA) Referral on Glimepiride/Metformin Fixed-Dose Combinations. This document provides information related to the regulatory review and scientific evaluation of glimepiride/metformin combination products.

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Glimepiride: Evidence-based facts, comparisons and clinical recommendations. This research article evaluates the evidence based facts about Glimepiride. [PMC3309420]

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Marketer / Manufacturer Details

SANOFI INDIA LIMITED

Country of Origin -

India

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