OPGLIM M 1MG TABLET 10'S
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OPGLIM M 1MG TABLET 10'S
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OPGLIM M 1MG TABLET 10'S

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OPGLIM M 1MG TABLET 10'S

By OPSIS CARE LIFESCIENCES PVT LTD

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115

₹97.75

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About OPGLIM M 1MG TABLET 10'S

  • OPGLIM M 1MG TABLET is a combination medicine used to treat type 2 diabetes mellitus. It combines two oral antidiabetic drugs to control high blood sugar levels in adults when diet and exercise alone are not enough. This medication helps the body use insulin more effectively and also reduces the amount of glucose produced by the liver.
  • The active ingredients in OPGLIM M 1MG TABLET are Oglim and Metformin. Oglim is a sulfonylurea that works by increasing the release of insulin from the pancreas, thereby lowering blood glucose. Metformin, a biguanide, decreases glucose production in the liver and improves insulin sensitivity in peripheral tissues. This dual action helps to effectively manage blood sugar levels.
  • OPGLIM M 1MG TABLET is typically taken once or twice daily with meals to minimize gastrointestinal side effects. The dosage is determined by your doctor based on your blood sugar levels and response to treatment. It is crucial to follow your doctor’s instructions carefully and maintain a healthy diet and regular exercise routine while taking this medication. Regular monitoring of blood sugar levels is also essential to ensure optimal control.
  • Common side effects of OPGLIM M 1MG TABLET may include nausea, diarrhea, abdominal pain, and hypoglycemia (low blood sugar). Hypoglycemia can occur if you skip a meal, exercise excessively, or take other medications that lower blood sugar. It's important to recognize the symptoms of hypoglycemia, such as sweating, shaking, and confusion, and have a quick source of sugar available.
  • OPGLIM M 1MG TABLET should be used with caution in patients with kidney or liver problems, heart disease, or a history of pancreatitis. It is also not recommended for use during pregnancy or breastfeeding. Always inform your doctor about any other medications you are taking, including over-the-counter drugs and herbal supplements, as they may interact with OPGLIM M 1MG TABLET.

Uses of OPGLIM M 1MG TABLET 10'S

  • Treatment of Type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Improve blood sugar control
  • Management of insulin resistance associated with polycystic ovary syndrome (PCOS)

How OPGLIM M 1MG TABLET 10'S Works

  • OPGLIM M 1MG TABLET 10'S is a combination medicine designed to manage type 2 diabetes mellitus. It combines two active ingredients: glimepiride and metformin. Each component works through distinct mechanisms to lower blood glucose levels and improve glycemic control.
  • Glimepiride belongs to a class of drugs called sulfonylureas. It primarily works by stimulating the release of insulin from the pancreatic beta cells. When blood glucose levels rise, glimepiride enhances insulin secretion, helping the body utilize glucose more effectively. Specifically, glimepiride binds to the sulfonylurea receptor on the beta cell membrane. This binding closes ATP-sensitive potassium channels, leading to depolarization of the cell. Depolarization opens voltage-gated calcium channels, causing an influx of calcium ions. The increased intracellular calcium triggers the exocytosis of insulin-containing granules, resulting in insulin release into the bloodstream. By increasing insulin secretion, glimepiride helps to lower blood sugar levels after meals and throughout the day.
  • Metformin, on the other hand, belongs to the biguanide class of drugs. Its primary mechanism of action involves reducing hepatic glucose production. The liver is a major source of glucose, and in individuals with type 2 diabetes, the liver often produces excessive amounts of glucose. Metformin suppresses gluconeogenesis, the process by which the liver synthesizes glucose from non-carbohydrate sources. Metformin activates an enzyme called AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor that regulates glucose and lipid metabolism. Activation of AMPK inhibits hepatic glucose production and increases insulin sensitivity in peripheral tissues such as muscle and fat. It also enhances glucose uptake and utilization by these tissues, contributing to lower blood glucose levels. Furthermore, metformin may also slow down the absorption of glucose from the intestines and improve insulin sensitivity in the body.
  • In combination, glimepiride and metformin provide complementary mechanisms to effectively lower blood glucose levels. Glimepiride stimulates insulin release to address insulin deficiency, while metformin reduces hepatic glucose production and improves insulin sensitivity to combat insulin resistance. This dual action helps to achieve better glycemic control in patients with type 2 diabetes. It is important to note that OPGLIM M 1MG TABLET 10'S is typically prescribed as part of a comprehensive diabetes management plan, which includes lifestyle modifications such as diet and exercise.

Side Effects of OPGLIM M 1MG TABLET 10'SArrow

The common side effects of Opglim M 1mg Tablet may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and hypoglycemia (low blood sugar). Other possible side effects are headache, dizziness, constipation, upper respiratory tract infection, and skin reactions like rash or itching. Less common but potentially serious side effects include lactic acidosis (muscle cramps, difficulty breathing, abdominal pain), and liver problems (yellowing of skin/eyes, dark urine, persistent nausea). In rare cases, it can cause a decrease in blood cell counts. Contact your doctor immediately if you experience any severe or persistent side effects.

Safety Advice for OPGLIM M 1MG TABLET 10'SArrow

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Allergies

Allergies

Do not use Opglim M 1mg Tablet 10'S if you are allergic to it or any of its ingredients.

Dosage of OPGLIM M 1MG TABLET 10'SArrow

  • The recommended dosage of OPGLIM M 1MG TABLET 10'S varies depending on individual patient needs, blood glucose levels, and response to treatment. Your doctor will determine the appropriate dosage for you. Typically, the starting dose is low and gradually increased to minimize the risk of side effects, particularly hypoglycemia (low blood sugar).
  • OPGLIM M 1MG TABLET 10'S is usually taken once or twice daily with meals. Taking it with food helps to reduce gastrointestinal side effects and improves absorption. It is crucial to take the tablet at the same time(s) each day to maintain consistent blood glucose control. Do not crush, chew, or break the tablet; swallow it whole with a glass of water.
  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. It is important to adhere to the prescribed dosage and timing to achieve optimal results. Regular monitoring of blood glucose levels is essential to ensure the medication is working effectively and to adjust the dosage if necessary. Your doctor may also recommend periodic blood tests to assess kidney function and other relevant parameters.
  • The maximum recommended daily dose of OPGLIM M should not be exceeded. Always follow your doctor's instructions carefully, and do not change the dosage without consulting them. Be aware of the symptoms of hypoglycemia, such as sweating, shakiness, dizziness, and confusion, and take appropriate action if they occur. Take 'OPGLIM M 1MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of OPGLIM M 1MG TABLET 10'S?Arrow

  • If you miss a dose of OPGLIM M 1MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How to store OPGLIM M 1MG TABLET 10'S?Arrow

  • Keep OPGLIM M 1MG TAB 1X10 away from the reach of children and pets.
  • Store OPGLIM M 1MG TAB 1X10 at room temperature.

Benefits of OPGLIM M 1MG TABLET 10'SArrow

  • OPGLIM M 1MG TABLET 10'S offers a multifaceted approach to managing type 2 diabetes, effectively combining two powerful medications to achieve optimal blood sugar control. This dual-action mechanism provides a range of benefits for individuals seeking to maintain healthy glucose levels and reduce the risk of diabetes-related complications.
  • One of the primary benefits of OPGLIM M 1MG TABLET 10'S is its ability to lower blood sugar levels. Glimipiride, a sulfonylurea, stimulates the pancreas to release more insulin, while Metformin enhances insulin sensitivity in the body's tissues and reduces glucose production in the liver. This synergistic effect leads to significant improvements in both fasting and postprandial blood sugar levels.
  • By effectively controlling blood sugar, OPGLIM M 1MG TABLET 10'S plays a crucial role in reducing the risk of long-term complications associated with diabetes. These complications can include cardiovascular disease, nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy). Maintaining stable blood sugar levels helps protect these vital organs and systems from the harmful effects of prolonged hyperglycemia.
  • OPGLIM M 1MG TABLET 10'S may also contribute to weight management. Metformin, one of its active ingredients, has been shown to have a mild weight-reducing effect in some individuals. This can be particularly beneficial for overweight or obese individuals with type 2 diabetes, as weight loss can improve insulin sensitivity and overall metabolic health.
  • Furthermore, OPGLIM M 1MG TABLET 10'S can improve HbA1c levels. HbA1c is a measure of average blood sugar control over the past 2-3 months. By lowering blood sugar levels consistently, this medication helps individuals achieve and maintain target HbA1c levels, indicating better long-term diabetes management.
  • OPGLIM M 1MG TABLET 10'S offers the convenience of a single tablet combining two medications, which can simplify the treatment regimen and improve adherence. This is especially helpful for individuals who may find it challenging to take multiple medications throughout the day. Improved adherence leads to better blood sugar control and overall health outcomes.
  • This medication can also lead to a decrease in microvascular and macrovascular complications. Consistent blood sugar control reduces the risk of damage to small blood vessels (microvascular) and large blood vessels (macrovascular), preventing conditions like kidney disease, nerve damage, heart attack, and stroke.
  • OPGLIM M 1MG TABLET 10'S is often prescribed when diet and exercise alone are not sufficient to control blood sugar levels in individuals with type 2 diabetes. It serves as an effective adjunct to lifestyle modifications, helping to achieve and maintain target blood sugar levels. It's also cost-effective, providing a valuable treatment option, and enhancing patients' quality of life by reducing diabetes-related symptoms and improving overall well-being.

How to use OPGLIM M 1MG TABLET 10'SArrow

  • OPGLIM M 1MG TABLET 10'S is an oral medication primarily prescribed to manage type 2 diabetes. It combines two active ingredients to help control blood sugar levels. To ensure safe and effective use, it's crucial to adhere to your doctor's instructions and the guidelines provided below.
  • The usual starting dose of OPGLIM M is determined by your doctor, based on your blood sugar levels and other medications you may be taking. It is generally taken once or twice daily, preferably with meals. Taking it with food helps to minimize potential stomach upset.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your system.
  • Consistency is key for optimal results. Try to take OPGLIM M at the same time(s) each day. This helps maintain a steady level of medication in your bloodstream.
  • Regularly monitor your blood sugar levels as directed by your doctor or diabetes educator. This will help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan.
  • OPGLIM M is most effective when combined with a healthy diet and regular exercise. Follow the dietary recommendations provided by your doctor or a registered dietitian and aim for at least 30 minutes of moderate-intensity exercise most days of the week.
  • It's important to inform your doctor about all other medications you are taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements, as they may interact with OPGLIM M.
  • Be aware of the potential side effects of OPGLIM M, such as nausea, vomiting, diarrhea, and low blood sugar (hypoglycemia). If you experience any severe or persistent side effects, contact your doctor immediately.
  • If you miss a dose of OPGLIM M, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • Store OPGLIM M at room temperature, away from heat, moisture, and direct sunlight. Keep it out of the reach of children.
  • It is advisable to consult your doctor if you are planning for any surgery or dental procedure, as your medication schedule may need to be adjusted temporarily. Always carry your medication list with you and inform healthcare professionals about your diabetes and the medications you are taking.
  • This medicine is not recommended for children below 18 years of age. While taking this medicine, avoid alcohol intake.

Quick Tips for OPGLIM M 1MG TABLET 10'SArrow

  • Take OPGLIM M 1MG TABLET 10'S as prescribed by your doctor. It's crucial to follow the dosage and timing instructions provided, as this medication works best when taken consistently at the same time each day, preferably with meals to minimize stomach upset. Never adjust the dosage yourself; always consult your healthcare provider for any changes.
  • Monitor your blood sugar levels regularly while taking OPGLIM M 1MG TABLET 10'S. Keep a log of your readings and share them with your doctor during follow-up appointments. This helps in assessing the effectiveness of the medication and making necessary adjustments to your treatment plan. Understanding how your body responds to the medication is essential for optimal diabetes management.
  • Be aware of the symptoms of hypoglycemia (low blood sugar) while on OPGLIM M 1MG TABLET 10'S. These may include sweating, shaking, dizziness, rapid heartbeat, confusion, and hunger. Always carry a source of fast-acting sugar, such as glucose tablets or juice, to quickly raise your blood sugar levels if hypoglycemia occurs. Inform your family and friends about the signs of hypoglycemia and how to assist you if needed.
  • Maintain a healthy lifestyle alongside taking OPGLIM M 1MG TABLET 10'S. This includes following a balanced diet rich in fruits, vegetables, and whole grains, and low in processed foods, sugary drinks, and saturated fats. Engage in regular physical activity, such as brisk walking, jogging, or swimming, for at least 30 minutes most days of the week. A healthy lifestyle can significantly improve blood sugar control and overall well-being.
  • Inform your doctor about all other medications, supplements, and herbal remedies you are taking before starting OPGLIM M 1MG TABLET 10'S. Certain medications can interact with Oglim M and affect its efficacy or increase the risk of side effects. It's especially important to disclose any medications that can affect blood sugar levels, such as corticosteroids or diuretics. Also, if you are scheduled for any surgery or medical procedures, inform your doctor that you are taking Oglim M.

Food Interactions with OPGLIM M 1MG TABLET 10'SArrow

  • OPGLIM M 1MG TABLET 10'S can be taken with or without food, but it is generally recommended to take it with meals to reduce the risk of stomach upset. Consistent timing with meals helps maintain stable blood sugar levels. Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of hypoglycemia (low blood sugar). Be mindful of your carbohydrate intake and maintain a balanced diet as advised by your healthcare provider.

FAQs

What is Opglim M 1mg Tablet 10's?Arrow

Opglim M 1mg Tablet 10's is a combination medicine used to control high blood sugar levels in people with type 2 diabetes mellitus.

How does Opglim M 1mg Tablet 10's work?Arrow

Opglim M 1mg Tablet 10's works through a combination of two medicines: Glimepiride and Metformin. Glimepiride works by increasing the amount of insulin released by the pancreas to lower blood sugar. Metformin works by decreasing the amount of glucose produced by the liver.

What are the common side effects of Opglim M 1mg Tablet 10's?Arrow

Common side effects of Opglim M 1mg Tablet 10's include nausea, vomiting, diarrhea, stomach pain, and loss of appetite.

How to store Opglim M 1mg Tablet 10's?Arrow

Store Opglim M 1mg Tablet 10's at room temperature, away from moisture and heat.

Is Opglim M 1mg Tablet 10's safe during pregnancy?Arrow

There is not enough information available regarding the safety of Opglim M 1mg Tablet 10's during pregnancy. Therefore, it should only be used if clearly prescribed by a doctor.

Is Opglim M 1mg Tablet 10's safe during breastfeeding?Arrow

It is not known whether Opglim M 1mg Tablet 10's passes into breast milk. Therefore, it is important to consult a doctor before using it during breastfeeding.

Is Opglim M 1mg Tablet 10's safe for people with kidney disease?Arrow

People with kidney disease should use Opglim M 1mg Tablet 10's with caution, as it may worsen kidney problems.

Is Opglim M 1mg Tablet 10's safe for people with liver disease?Arrow

People with liver disease should use Opglim M 1mg Tablet 10's with caution, as it may worsen liver problems.

Can Opglim M 1mg Tablet 10's be taken with other medications?Arrow

Opglim M 1mg Tablet 10's can interact with other medications. Therefore, it is important to tell your doctor before starting any new medication.

What to do in case of an overdose of Opglim M 1mg Tablet 10's?Arrow

In case of an overdose of Opglim M 1mg Tablet 10's, contact a doctor immediately or go to the nearest hospital.

Is it safe to drink alcohol while taking Opglim M 1mg Tablet 10's?Arrow

Drinking alcohol while taking Opglim M 1mg Tablet 10's can lower blood sugar levels.

What foods should be avoided while using Opglim M 1mg Tablet 10's?Arrow

While using Opglim M 1mg Tablet 10's, sugary foods and drinks should be avoided.

What are the alternatives to Opglim M 1mg Tablet 10's?Arrow

Alternatives to Opglim M 1mg Tablet 10's include other anti-diabetic medications, such as sulfonylureas, metformin alone, TZDs, DPP-4 inhibitors and SGLT2 inhibitors.

What are other brands containing Glimepiride and Metformin?Arrow

Other brands containing Glimepiride and Metformin include: Amaryl M, Glimisave M, and Metglim.

How often should I check my blood sugar levels while using Opglim M 1mg Tablet 10's?Arrow

Talk to your doctor to find out how often you should check your blood sugar levels while using Opglim M 1mg Tablet 10's.

References

Book Icon

DrugBank: Glimipiride. Provides comprehensive chemical and pharmaceutical information on Glimepiride, including its mechanism of action, pharmacokinetics, and interactions.

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FDA (Food and Drug Administration) prescribing information for Amaryl (Glimepiride). Contains detailed information about the drug's usage, dosage, side effects, and clinical studies.

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National Center for Biotechnology Information (NCBI): Sulfonylureas in the Treatment of Type 2 Diabetes. A review article discussing the use of sulfonylureas, including glimepiride, in managing type 2 diabetes.

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European Medicines Agency (EMA): Glimepiride. Provides regulatory information and scientific assessments related to glimepiride.

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UpToDate: Glimepiride drug information. Clinical resource providing information on glimepiride, including its pharmacology, dosing, and adverse effects (Subscription Required).

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