BIOVORIN 50MG/5ML INJECTION
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BIOVORIN 50MG/5ML INJECTION
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BIOVORIN 50MG/5ML INJECTION

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BIOVORIN 50MG/5ML INJECTION

By ZYDUS LIFESCIENCES LIMITED

MRP

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474

₹240

49.37 % OFF

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Product DetailsArrow

About BIOVORIN 50MG/5ML INJECTION

  • BIOVORIN 50MG/5ML INJECTION contains Leucovorin calcium, a substance related to folic acid, a type of vitamin. Classified as a folic acid analog, it serves multiple crucial roles in patient care. Primarily, it's administered to mitigate the adverse effects of methotrexate, a powerful medication used in cancer treatment. This is especially important because methotrexate can interfere with the body's ability to use folic acid, leading to serious side effects. BIOVORIN 50MG/5ML INJECTION steps in to counteract this effect, protecting healthy cells from methotrexate's toxicity.
  • Furthermore, BIOVORIN 50MG/5ML INJECTION is a vital treatment for individuals who have experienced an accidental overdose of methotrexate or similar medications. In these situations, the drug helps to quickly restore normal folic acid levels and prevent potentially life-threatening complications. It is also frequently used in conjunction with other chemotherapy drugs to treat colorectal cancer, offering a synergistic approach to combatting this challenging disease. Its ability to enhance the effectiveness of certain cancer treatments while reducing side effects makes it an invaluable tool in oncology.
  • Beyond its role in cancer therapy, BIOVORIN 50MG/5ML INJECTION is also prescribed to treat anemia resulting from folic acid deficiency. By replenishing folic acid levels, the medication helps the body produce healthy red blood cells, alleviating symptoms of fatigue, weakness, and other complications associated with anemia. However, it's important to note that BIOVORIN 50MG/5ML INJECTION should not be used in cases of anemia caused by vitamin B12 deficiency (pernicious anemia or megaloblastic anemia), as it can mask the underlying condition and lead to neurological damage.
  • It's crucial to inform your doctor if you have any allergies to Leucovorin calcium, calcium folinate, or any other ingredients in the injection. Also, disclose any pre-existing medical conditions such as anemia, kidney problems, heart issues, or liver disorders before starting treatment. Be sure to tell your doctor about any medications you are currently taking, especially those used to treat seizures, as they may interact with BIOVORIN 50MG/5ML INJECTION. Seek immediate medical attention if you experience any allergic reaction symptoms, such as wheezing, difficulty breathing, skin rash, itching, hives, or swelling of the lips, face, or tongue.

Uses of BIOVORIN 50MG/5ML INJECTION

  • Management of methotrexate overdose and mitigation of its toxic effects
  • Prevention of detrimental effects caused by methotrexate or analogous medications
  • Treatment of Colorectal cancer
  • Management of Anemia

Side Effects of BIOVORIN 50MG/5ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. BIOVORIN 50MG/5ML INJECTION can cause both common and serious side effects.

  • Diarrhea
  • Nausea
  • Vomiting
  • Inflammmed and sore mouth
  • Tiredness
  • Allergic reactions

Safety Advice for BIOVORIN 50MG/5ML INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

There is a limited number of studies on the safety of BIOVORIN 50MG/5ML INJECTION during pregnancy, and it is unknown whether the medicine can be given during pregnancy. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.

Dosage of BIOVORIN 50MG/5ML INJECTIONArrow

  • BIOVORIN 50MG/5ML INJECTION will be administered to you by a trained healthcare professional, such as a physician or nurse experienced in cancer chemotherapy. The precise dosage and duration of your treatment will be determined by your doctor, who will carefully consider several factors, including the specific type and stage of your disease, its severity, your overall health, and how well you are responding to the medication.
  • This medication is typically administered either intravenously (directly into a vein) or intramuscularly (directly into a muscle). The route of administration will depend on your individual disease condition and the specific recommendations of your doctor. They will choose the method that is most effective and appropriate for your situation.
  • It is important to adhere to the schedule and dosage prescribed by your doctor. Do not attempt to self-administer BIOVORIN 50MG/5ML INJECTION or alter the dosage without consulting your healthcare provider. Doing so could potentially lead to complications or reduced effectiveness of the treatment. Your doctor will monitor you closely throughout the course of treatment to assess your response and make any necessary adjustments to your dosage or treatment plan.

How to store BIOVORIN 50MG/5ML INJECTION?Arrow

  • Keep BIOVORIN 50MG INJ 5ML away from the reach of children and pets.
  • Store BIOVORIN 50MG INJ 5ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of BIOVORIN 50MG/5ML INJECTIONArrow

  • BIOVORIN 50MG/5ML INJECTION is a medication that plays a crucial role in counteracting the effects of folic acid antagonists, a class of drugs that includes methotrexate and similar medications. These antagonists work by inhibiting the dihydrofolate reductase enzyme, which is essential for the body's utilization of folic acid. BIOVORIN 50MG/5ML INJECTION steps in to mitigate this inhibition, ensuring that cells can still access and utilize folic acid for vital processes.
  • Furthermore, BIOVORIN 50MG/5ML INJECTION is also valuable in treating certain types of anemia. Anemia often arises from a deficiency in folic acid, which is necessary for the formation of red blood cells. By providing a readily available source of folic acid, BIOVORIN 50MG/5ML INJECTION aids in red blood cell production, helping to restore healthy blood levels and alleviate the symptoms of anemia.
  • In the context of cancer treatment, BIOVORIN 50MG/5ML INJECTION is used in conjunction with another anticancer medication called 5-fluorouracil (5-FU) specifically in treating colorectal cancer. It enhances the therapeutic effects of 5-FU, increasing its effectiveness in targeting and destroying cancer cells. This combination therapy strategy allows for a more potent attack on cancerous cells, leading to improved treatment outcomes.
  • Essentially, BIOVORIN 50MG/5ML INJECTION acts as a rescue medication, safeguarding the body's access to folic acid during treatments that might otherwise disrupt its utilization. Its versatility extends from counteracting drug effects to treating anemia and boosting cancer therapy, underscoring its significance in various medical scenarios.

How to use BIOVORIN 50MG/5ML INJECTIONArrow

  • BIOVORIN 50MG/5ML INJECTION will be administered to you by a qualified healthcare professional, such as a physician or nurse specializing in cancer chemotherapy. This ensures the drug is given safely and effectively.
  • Your doctor will carefully determine the most appropriate dose and duration of treatment with BIOVORIN 50MG/5ML INJECTION. This decision is based on several factors, including the specific type and stage of your disease, its severity, your overall health condition, and how well you respond to the medication.
  • The method of administration, whether intravenously (directly into a vein) or intramuscularly (directly into a muscle), will also be determined by your doctor based on your specific medical needs and the characteristics of your condition. Intravenous administration allows the medication to enter your bloodstream quickly, while intramuscular administration provides a slower, more sustained release.
  • It is crucial to follow your doctor's instructions precisely regarding the schedule and duration of your BIOVORIN 50MG/5ML INJECTION treatment. Do not miss any scheduled appointments, and inform your healthcare provider immediately if you experience any unusual or concerning side effects during the course of your treatment. Close monitoring and communication with your medical team are essential for optimal outcomes.

FAQs

<p style="text-align:justify;">Why is BIOVORIN 50MG/5ML INJECTION given 24 hours after methotrexate?</p>Arrow

BIOVORIN 50MG/5ML INJECTION is usually administered 24 hours after methotrexate so that it does not interfere with the therapeutic effect of methotrexate. It can also be used in methotrexate overdose; it should be administered as soon as possible.

<p style="text-align:justify;">Can BIOVORIN 50MG/5ML INJECTION cause swelling?</p>Arrow

BIOVORIN 50MG/5ML INJECTION may cause allergic reactions like rash, low blood pressure, wheezing, shortness of breath, and swelling of the face or throat.

<p style="text-align:justify;">Can BIOVORIN 50MG/5ML INJECTION cause seizures?</p>Arrow

There is no evidence that BIOVORIN 50MG/5ML INJECTION cause seizures. But the medicine can affect the effect of seizure medication when administered concurrently. Inform your physician about all your medicines, including over-the-counter medications.

<p>How long does it take for BIOVORIN 50MG/5ML INJECTION to work?</p>Arrow

BIOVORIN 50MG/5ML INJECTION starts acting on the body within 5 minutes of administration. However, this might vary with respect to dosage, the patient receiving the drug, and response to treatment.

<p>What measures should be taken to ensure the prompt excretion of methotrexate during treatment with BIOVORIN 50MG/5ML INJECTION?</p>Arrow

A healthcare professional will monitor you during the treatment with this medicine. Maintenance of urine output above 2,500 mL/24hr in adults by increasing oral or intravenous fluids 12 hours before and for 36 hours after the end of methotrexate infusion. To monitor the alkalinization of urine (this enhances drug excretion) so that the urinary pH is greater than 7.0 before methotrexate infusion. Foods, drinks, and drugs that may increase urinary acidity should be avoided during the therapy. Finally, blood methotrexate concentration should be measured at least 24, 48, and 72 hours after the initiation of the methotrexate infusion.

NULL interaction of BIOVORIN 50MG/5ML INJECTION with other drungsArrow

NULL interaction of BIOVORIN 50MG/5ML INJECTION with other drungs

<p style="text-align:justify;">If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking these medicinal products. Inform your doctor if you have vomited immediately after receiving the injection. If you accidentally take too much BIOVORIN 50MG/5ML INJECTION. contact your doctor and seek medical advice immediately. Do not stop taking this medicine unless your doctor tells you to. Your doctor will regularly do lab tests to check the effectiveness of the medicine.&nbsp;</p> is an advice related to BIOVORIN 50MG/5ML INJECTIONArrow

If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking these medicinal products. Inform your doctor if you have vomited immediately after receiving the injection. If you accidentally take too much BIOVORIN 50MG/5ML INJECTION. contact your doctor and seek medical advice immediately. Do not stop taking this medicine unless your doctor tells you to. Your doctor will regularly do lab tests to check the effectiveness of the medicine. 

is an advice related to BIOVORIN 50MG/5ML INJECTION

LEUCOVORIN CALCIUM is molecule/combination used for making BIOVORIN 50MG/5ML INJECTION.Arrow

LEUCOVORIN CALCIUM is molecule/combination used for making BIOVORIN 50MG/5ML INJECTION

For which ailments/diseases/conditions BIOVORIN 50MG/5ML INJECTION is prescribed?Arrow

BIOVORIN 50MG/5ML INJECTION is prescribed for Oncology ailments/diseases/conditions.

References

Book Icon

Calcium Folinate 10 mg/ml Injection - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk. 2020

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HIGHLIGHTS OF PRESCRIBING INFORMATION [Internet].

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BIOVORIN 50MG/5ML INJECTION

BIOVORIN 50MG/5ML INJECTION

MRP

₹

474

₹240

49.37 % OFF

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