RECOVORIN 50 INJECTION
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RECOVORIN 50 INJECTION
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RECOVORIN 50 INJECTION

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RECOVORIN 50 INJECTION

By CADILA PHARMACEUTICALS PRIVATE LIMITED

MRP

291

₹247.35

15 % OFF

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Product DetailsArrow

About RECOVORIN 50 INJECTION

  • RECOVORIN 50 INJECTION contains leucovorin calcium, a substance closely related to folic acid, a vital vitamin. It belongs to the class of medications known as folic acid analogs. RECOVORIN 50 INJECTION primarily serves to mitigate the harmful effects of methotrexate, a medication used in the treatment of certain cancers. It is crucial in cases where patients accidentally overdose on methotrexate or similar drugs.
  • Furthermore, RECOVORIN 50 INJECTION is used in conjunction with other anticancer medications to combat colorectal cancer, which originates in the colon or rectum. Beyond cancer treatment, this medication addresses anemia resulting from folic acid deficiency in the body. Leucovorin calcium works by providing the body with a readily usable form of folic acid, which helps to counteract the effects of methotrexate and supports healthy cell growth and function, especially in conditions where folic acid levels are insufficient.
  • Before taking RECOVORIN 50 INJECTION, inform your doctor if you have any allergies to leucovorin calcium, calcium folinate, or any other ingredients in the medication. It is contraindicated in certain types of anemia, such as pernicious anemia or megaloblastic anemia, associated with vitamin B12 deficiency. Disclose any pre-existing medical conditions, including anemia, kidney, heart, or liver problems, to your physician before commencing treatment. Also, inform your physician if you are currently taking any medications for seizure control. Immediately report any symptoms such as wheezing, difficulty breathing, skin rash, itching, hives, or swelling of the lips, face, or tongue to your physician.

Uses of RECOVORIN 50 INJECTION

  • Managing Methotrexate Overdose and Toxicity: Addressing the risks and complications associated with excessive methotrexate levels in the body, requiring immediate medical intervention.
  • Preventing the Harmful Effects of Methotrexate or Similar Medications: Strategies to minimize adverse reactions and side effects from methotrexate and related drugs, ensuring patient safety and well-being.
  • Colorectal Cancer Treatment Support: As part of a treatment plan for colorectal cancer, often in conjunction with other therapies.
  • Management of Anemia: Used in certain cases of anemia, particularly when related to folate deficiency or other specific underlying causes.

Side Effects of RECOVORIN 50 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Diarrhea
  • Nausea
  • Vomiting
  • Inflammmed and sore mouth
  • Tiredness
  • Allergic reactions

Safety Advice for RECOVORIN 50 INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

There is a limited number of studies on the safety of RECOVORIN 50 INJECTION during pregnancy, and it is unknown whether the medicine can be given during pregnancy. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.

Dosage of RECOVORIN 50 INJECTIONArrow

  • A qualified healthcare professional, such as a physician or nurse specializing in cancer chemotherapy, will administer RECOVORIN 50 INJECTION to you. They have the expertise to handle the medication safely and effectively.
  • Your doctor will carefully determine the appropriate dose and duration of your treatment. This decision will be based on a comprehensive assessment of your specific disease, its severity, and other individual health factors. This personalized approach ensures you receive the most beneficial treatment plan.
  • The medicine is administered either intravenously, meaning directly into your vein, or intramuscularly, meaning directly into your muscle. The specific method of administration will depend on your particular medical condition and the doctor's professional judgment. The healthcare provider will explain the chosen method and ensure your comfort during the process.
  • It's crucial to adhere to the prescribed dosage and schedule provided by your doctor. Do not attempt to self-administer RECOVORIN 50 INJECTION or alter the treatment plan without consulting your healthcare provider. This medication requires careful monitoring and adjustments by trained professionals to ensure its effectiveness and minimize potential side effects.

How to store RECOVORIN 50 INJECTION?Arrow

  • Keep RECOVORIN 50MG INJ 5ML away from the reach of children and pets.
  • Store RECOVORIN 50MG INJ 5ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of RECOVORIN 50 INJECTIONArrow

  • RECOVORIN 50 INJECTION is a medication designed to counteract the effects of folic acid antagonists, such as methotrexate. These antagonists work by inhibiting the dihydrofolate reductase enzyme, which is crucial for converting folic acid into its active form. By interfering with this process, these medications can disrupt cell growth, particularly in rapidly dividing cells like cancer cells. RECOVORIN 50 INJECTION essentially reverses this effect, ensuring that cells have access to the necessary active form of folic acid.
  • This medication also plays a crucial role in treating anemia, specifically those caused by folic acid deficiency. Folic acid is essential for the formation of red blood cells, which carry oxygen throughout the body. When folic acid levels are low, the body cannot produce enough healthy red blood cells, leading to anemia. RECOVORIN 50 INJECTION provides the body with the required folic acid, thereby supporting red blood cell production and alleviating anemia symptoms.
  • Furthermore, RECOVORIN 50 INJECTION is used in conjunction with the anticancer medication 5-fluorouracil (5-FU) in the treatment of colorectal cancer. In this context, RECOVORIN 50 INJECTION enhances the effectiveness of 5-FU by promoting its binding to a specific enzyme in cancer cells, leading to increased cell death. This synergistic effect makes RECOVORIN 50 INJECTION an important component of certain colorectal cancer treatment regimens.

How to use RECOVORIN 50 INJECTIONArrow

  • RECOVORIN 50 INJECTION will be administered to you by a trained physician or nurse experienced in cancer chemotherapy. This ensures the medication is given safely and effectively. The dosage and duration of your treatment will be determined by your doctor, who will consider several factors, including the type and severity of your condition, your overall health, and how well you respond to the medication. It's crucial to follow your doctor's instructions precisely.
  • The method of administration will also depend on your specific condition. RECOVORIN 50 INJECTION can be given intravenously, meaning it's injected directly into a vein, or intramuscularly, which means it's injected into a muscle. Your doctor will choose the most appropriate route for you. If administered intravenously, the injection will likely be given slowly over a period of time. If administered intramuscularly, the injection site will be carefully chosen to minimize discomfort.
  • It is important to discuss any concerns or questions you have about the administration of RECOVORIN 50 INJECTION with your doctor or nurse. They can explain the procedure in more detail and address any anxieties you may have. Remember, open communication is key to ensuring you feel comfortable and confident throughout your treatment. Do not hesitate to reach out to your healthcare team for support and clarification.

FAQs

Why is RECOVORIN 50 INJECTION given 24 hours after methotrexate?Arrow

RECOVORIN 50 INJECTION is usually administered 24 hours after methotrexate so that it does not interfere with the therapeutic effect of methotrexate. It can also be used in methotrexate overdose; it should be administered as soon as possible.

Can RECOVORIN 50 INJECTION cause swelling?Arrow

RECOVORIN 50 INJECTION may cause allergic reactions like rash, low blood pressure, wheezing, shortness of breath, and swelling of the face or throat.

Can RECOVORIN 50 INJECTION cause seizures?Arrow

There is no evidence that RECOVORIN 50 INJECTION cause seizures. But the medicine can affect the effect of seizure medication when administered concurrently. Inform your physician about all your medicines, including over-the-counter medications.

How long does it take for RECOVORIN 50 INJECTION to work?Arrow

RECOVORIN 50 INJECTION starts acting on the body within 5 minutes of administration. However, this might vary with respect to dosage, the patient receiving the drug, and response to treatment.

What measures should be taken to ensure the prompt excretion of methotrexate during treatment with RECOVORIN 50 INJECTION?Arrow

A healthcare professional will monitor you during the treatment with this medicine. Maintenance of urine output above 2,500 mL/24hr in adults by increasing oral or intravenous fluids 12 hours before and for 36 hours after the end of methotrexate infusion. To monitor the alkalinization of urine (this enhances drug excretion) so that the urinary pH is greater than 7.0 before methotrexate infusion. Foods, drinks, and drugs that may increase urinary acidity should be avoided during the therapy. Finally, blood methotrexate concentration should be measured at least 24, 48, and 72 hours after the initiation of the methotrexate infusion.

NULL interaction of RECOVORIN 50 INJECTION with other drungsArrow

There is no known interaction of RECOVORIN 50 INJECTION with other drugs.

What advice should I follow while taking RECOVORIN 50 INJECTION?Arrow

If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking these medicinal products. Inform your doctor if you have vomited immediately after receiving the injection. If you accidentally take too much RECOVORIN 50 INJECTION. contact your doctor and seek medical advice immediately. Do not stop taking this medicine unless your doctor tells you to. Your doctor will regularly do lab tests to check the effectiveness of the medicine.

What molecule/combination is used for making RECOVORIN 50 INJECTION?Arrow

LEUCOVORIN CALCIUM is molecule/combination used for making RECOVORIN 50 INJECTION.

For which ailments/diseases/conditions is RECOVORIN 50 INJECTION prescribed?Arrow

RECOVORIN 50 INJECTION is prescribed for Oncology ailments/diseases/conditions.

References

Book Icon

Calcium Folinate 10 mg/ml Injection - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk. 2020.

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HIGHLIGHTS OF PRESCRIBING INFORMATION [Internet].

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Marketer / Manufacturer Details

CADILA PHARMACEUTICALS PRIVATE LIMITED

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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