ONCOVORIN 50MG/5ML INJECTION
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ONCOVORIN 50MG/5ML INJECTION
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ONCOVORIN 50MG/5ML INJECTION

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ONCOVORIN 50MG/5ML INJECTION

By BANGALORE PHARMACEUTICAL & RESEARCH LABORATORY (P) LTD

MRP

₹

358

₹107

70.11 % OFF

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Product DetailsArrow

About ONCOVORIN 50MG/5ML INJECTION

  • ONCOVORIN 50MG/5ML INJECTION contains leucovorin calcium, a substance related to folic acid, a crucial vitamin. As a folic acid analog, it counteracts the adverse effects of methotrexate, a drug used in cancer treatment. It's also vital in managing accidental methotrexate overdoses or similar medication toxicities. Furthermore, it's combined with other anticancer drugs to combat colorectal cancer.
  • Beyond cancer treatment, ONCOVORIN 50MG/5ML INJECTION addresses anemia stemming from folic acid deficiency. This highlights its versatility in treating various health conditions. The drug functions by providing the body with a readily usable form of folate, essential for DNA synthesis and cell growth, particularly when these processes are threatened by medications like methotrexate.
  • Before using ONCOVORIN 50MG/5ML INJECTION, inform your doctor if you have allergies to leucovorin calcium, calcium folinate, or any of the injection's other ingredients. It's also crucial to disclose any history of pernicious anemia or megaloblastic anemia due to vitamin B12 deficiency. Pre-existing kidney, heart, or liver issues should also be reported. Alert your doctor if you are on seizure medications.
  • Immediately notify your physician if you experience symptoms like wheezing, breathing difficulties, skin rashes, itching, hives, or swelling of the lips, face, or tongue. These could indicate an allergic reaction. Your doctor will carefully assess your condition and medical history to determine the appropriate dosage and monitor for potential side effects, ensuring the safest and most effective treatment.

Uses of ONCOVORIN 50MG/5ML INJECTION

  • Management of Methotrexate overdose and reducing its toxicity
  • Preventing the harmful effects of methotrexate or similar medications, often used in conjunction with ONCOVORIN 50MG/5ML INJECTION.
  • Treatment of Colorectal cancer
  • Management of Anemia

Side Effects of ONCOVORIN 50MG/5ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, but not everyone experiences them. ONCOVORIN 50MG/5ML INJECTION can cause both common and serious side effects.

  • Diarrhea
  • Nausea
  • Vomiting
  • Inflamed and sore mouth
  • Tiredness
  • Allergic reactions

Safety Advice for ONCOVORIN 50MG/5ML INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

There is a limited number of studies on the safety of ONCOVORIN 50MG/5ML INJECTION during pregnancy, and it is unknown whether the medicine can be given during pregnancy. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.

Dosage of ONCOVORIN 50MG/5ML INJECTIONArrow

  • Your treatment will be administered by a qualified healthcare professional, such as a physician or nurse specializing in cancer chemotherapy. They are trained to handle these medications and ensure your safety and comfort throughout the process.
  • The dosage and duration of your ONCOVORIN 50MG/5ML INJECTION treatment will be carefully determined by your doctor. This decision is based on a thorough assessment of your individual condition, including the type and severity of your disease, your overall health, and any other relevant factors. This personalized approach ensures you receive the most effective and appropriate treatment plan.
  • The method of administration, whether intravenously (into a vein) or intramuscularly (into a muscle), will also be determined by your doctor based on your specific medical condition and the characteristics of the medication. Intravenous administration allows the drug to enter your bloodstream directly for rapid distribution, while intramuscular injection provides a slower, more sustained release.
  • Throughout your treatment, your healthcare team will closely monitor your progress and adjust the dosage as needed to optimize its effectiveness and minimize any potential side effects. It's important to communicate openly with your doctor and nurses about any concerns or symptoms you experience during your treatment.

How to store ONCOVORIN 50MG/5ML INJECTION?Arrow

  • Keep ONCOVORIN 50MG INJ 5ML away from the reach of children and pets.
  • Store ONCOVORIN 50MG INJ 5ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of ONCOVORIN 50MG/5ML INJECTIONArrow

  • ONCOVORIN 50MG/5ML INJECTION serves as a crucial rescue medication, effectively neutralizing the adverse effects of folic acid antagonists like methotrexate. These antagonists, while useful in treating certain conditions, can deplete essential folate levels in the body. ONCOVORIN 50MG/5ML INJECTION works by bypassing the blocked dihydrofolate reductase enzyme, ensuring that cells receive the necessary folate for vital functions.
  • In cases of anemia stemming from folate deficiency, ONCOVORIN 50MG/5ML INJECTION provides a readily available source of folic acid. This supplementation is critical for the production of healthy red blood cells, which are responsible for carrying oxygen throughout the body. By replenishing folate levels, ONCOVORIN 50MG/5ML INJECTION aids in restoring normal red blood cell production and alleviating the symptoms of anemia.
  • ONCOVORIN 50MG/5ML INJECTION plays a significant role in the treatment of colorectal cancer when used in conjunction with 5-fluorouracil (5-FU). It enhances the effectiveness of 5-FU by stabilizing the binding of 5-FU to its target enzyme in cancer cells. This synergistic effect leads to increased cancer cell death and improved treatment outcomes. The strategic use of ONCOVORIN 50MG/5ML INJECTION in combination with 5-FU is a common and effective approach in colorectal cancer therapy.

How to use ONCOVORIN 50MG/5ML INJECTIONArrow

  • ONCOVORIN 50MG/5ML INJECTION will be administered to you by a trained healthcare professional, such as a physician or nurse experienced in cancer chemotherapy. They will carefully handle the preparation and administration of this medication to ensure your safety and the effectiveness of the treatment.
  • Your doctor will determine the precise dosage and the duration of your treatment plan. This decision is based on a comprehensive assessment of your specific disease condition, its severity, and various other individual factors that influence how you respond to the medication. It's crucial to adhere to the prescribed treatment schedule for the best possible outcome.
  • The method of administration, whether intravenously (directly into your vein) or intramuscularly (directly into your muscle), will be determined by your doctor based on your specific medical condition and the characteristics of the medication. Intravenous administration allows the medication to enter your bloodstream directly, while intramuscular administration allows for a slower, more sustained release.
  • During the injection, the healthcare provider will monitor you closely for any signs of adverse reactions or complications. If you experience any unusual symptoms or discomfort during or after the injection, inform them immediately. Regular monitoring and open communication with your healthcare team are essential throughout your treatment.
  • It is important to maintain regular appointments with your doctor to evaluate the efficacy of the medication and monitor for any potential side effects. Do not miss any scheduled appointments, and be sure to discuss any concerns or questions you have with your healthcare provider.

FAQs

Why is ONCOVORIN 50MG/5ML INJECTION given 24 hours after methotrexate?Arrow

ONCOVORIN 50MG/5ML INJECTION is usually administered 24 hours after methotrexate so that it does not interfere with the therapeutic effect of methotrexate. It can also be used in methotrexate overdose; it should be administered as soon as possible.

Can ONCOVORIN 50MG/5ML INJECTION cause swelling?Arrow

ONCOVORIN 50MG/5ML INJECTION may cause allergic reactions like rash, low blood pressure, wheezing, shortness of breath, and swelling of the face or throat.

Can ONCOVORIN 50MG/5ML INJECTION cause seizures?Arrow

There is no evidence that ONCOVORIN 50MG/5ML INJECTION cause seizures. But the medicine can affect the effect of seizure medication when administered concurrently. Inform your physician about all your medicines, including over-the-counter medications.

How long does it take for ONCOVORIN 50MG/5ML INJECTION to work?Arrow

ONCOVORIN 50MG/5ML INJECTION starts acting on the body within 5 minutes of administration. However, this might vary with respect to dosage, the patient receiving the drug, and response to treatment.

What measures should be taken to ensure the prompt excretion of methotrexate during treatment with ONCOVORIN 50MG/5ML INJECTION?Arrow

A healthcare professional will monitor you during the treatment with this medicine. Maintenance of urine output above 2,500 mL/24hr in adults by increasing oral or intravenous fluids 12 hours before and for 36 hours after the end of methotrexate infusion. To monitor the alkalinization of urine (this enhances drug excretion) so that the urinary pH is greater than 7.0 before methotrexate infusion. Foods, drinks, and drugs that may increase urinary acidity should be avoided during the therapy. Finally, blood methotrexate concentration should be measured at least 24, 48, and 72 hours after the initiation of the methotrexate infusion.

NULL interaction of ONCOVORIN 50MG/5ML INJECTION with other drungsArrow

NULL interaction of ONCOVORIN 50MG/5ML INJECTION with other drugs

What advice should I be given regarding ONCOVORIN 50MG/5ML INJECTION?Arrow

If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking these medicinal products. Inform your doctor if you have vomited immediately after receiving the injection. If you accidentally take too much ONCOVORIN 50MG/5ML INJECTION. contact your doctor and seek medical advice immediately. Do not stop taking this medicine unless your doctor tells you to. Your doctor will regularly do lab tests to check the effectiveness of the medicine.

What is ONCOVORIN 50MG/5ML INJECTION made of?Arrow

ONCOVORIN 50MG/5ML INJECTION is made of LEUCOVORIN CALCIUM.

For what ailments/diseases/conditions is ONCOVORIN 50MG/5ML INJECTION prescribed?Arrow

ONCOVORIN 50MG/5ML INJECTION is prescribed for Oncology related ailments/diseases/conditions.

References

Book Icon

Calcium Folinate 10 mg/ml Injection - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk. 2020

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HIGHLIGHTS OF PRESCRIBING INFORMATION [Internet].

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Ratings & Review

Very responsive staff.All drugs available at store

Ronak Makwana

•

Reviewed on 16-01-2024

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(5/5)

Discount on medicine is good But OTC discount is zero and very low

Abhishek Solanki

•

Reviewed on 05-12-2022

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(3/5)

Quick service, getting discounts on medicines on regular basis

Harshit Patel

•

Reviewed on 12-02-2024

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(5/5)

Very good place for medicine allmost all the medicine are available at discounted rate.

Sachin Dodhiwala

•

Reviewed on 10-03-2024

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(5/5)

Can get the medicines here on pocket friendly rates !

Neha Pathak

•

Reviewed on 10-02-2024

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(5/5)

Marketer / Manufacturer Details

BANGALORE PHARMACEUTICAL & RESEARCH LABORATORY (P) LTD

Country of Origin -

India

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ONCOVORIN 50MG/5ML INJECTION

ONCOVORIN 50MG/5ML INJECTION

MRP

₹

358

₹107

70.11 % OFF

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