UNIFOLIN 50 INJECTION
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UNIFOLIN 50 INJECTION
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UNIFOLIN 50 INJECTION

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UNIFOLIN 50 INJECTION

By UNITED BIOTECH PVT LTD

MRP

312.9

₹177

43.43 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Neha Patel

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About UNIFOLIN 50 INJECTION

  • UNIFOLIN 50 INJECTION contains leucovorin calcium, a substance closely related to folic acid, a vital vitamin. Classified as a folic acid analog, this medication serves several important functions. Primarily, it's administered to mitigate the adverse effects of methotrexate, a drug commonly used in cancer treatment. It acts as a protective agent, reducing the toxicity associated with methotrexate and allowing for more effective cancer therapy.
  • Furthermore, UNIFOLIN 50 INJECTION is crucial in managing cases of methotrexate overdose, providing a rescue mechanism to counteract the drug's harmful effects. It's also employed alongside other anticancer drugs in the treatment of colorectal cancer, a prevalent form of cancer affecting the colon and rectum. In such cases, it enhances the effectiveness of the primary cancer treatment.
  • Beyond its role in cancer therapy, this injection addresses anemia resulting from folic acid deficiency. By replenishing folic acid levels in the body, it helps restore normal red blood cell production and alleviate the symptoms of anemia. It is important to note that UNIFOLIN 50 INJECTION is not a substitute for Vitamin B12, and should not be used in cases of pernicious anemia or megaloblastic anemia resulting from Vitamin B12 deficiency.
  • Before using UNIFOLIN 50 INJECTION, it is crucial to inform your doctor if you have any allergies to leucovorin calcium or any of the other ingredients in the medication. It's also important to discuss any pre-existing medical conditions, such as anemia, kidney problems, heart conditions, or liver issues. Patients taking medications for seizures should also notify their doctor, as interactions may occur. Seek immediate medical attention if you experience any signs of an allergic reaction, such as wheezing, difficulty breathing, skin rash, itching, hives, or swelling of the lips, face, or tongue.

Uses of UNIFOLIN 50 INJECTION

  • Management of Methotrexate overdose and reduction of toxicity
  • Preventing the harmful effects of methotrexate or similar medications
  • Treatment of Colorectal cancer
  • Management of Anemia

Side Effects of UNIFOLIN 50 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Diarrhea
  • Nausea
  • Vomiting
  • Inflammed and sore mouth
  • Tiredness
  • Allergic reactions

Safety Advice for UNIFOLIN 50 INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

There is a limited number of studies on the safety of UNIFOLIN 50 INJECTION during pregnancy, and it is unknown whether the medicine can be given during pregnancy. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.

Dosage of UNIFOLIN 50 INJECTIONArrow

  • UNIFOLIN 50 INJECTION will be administered to you by a trained healthcare professional, such as a physician or nurse, who specializes in cancer chemotherapy. The precise dosage and duration of your treatment will be determined by your doctor, taking into careful consideration several factors, including the specific type and stage of your disease, the severity of your condition, your overall health status, and how well you are responding to the treatment.
  • The medication is typically administered either intravenously, which means it is injected directly into your vein, or intramuscularly, which means it is injected directly into your muscle. The route of administration will depend on the specific characteristics of your disease and the most effective way to deliver the medication to achieve the best possible outcome. Your doctor will explain the chosen method and the reasons behind it.
  • It is crucial to follow your doctor's instructions precisely regarding the dosage and schedule of UNIFOLIN 50 INJECTION. Do not attempt to self-administer the medication or alter the prescribed dosage in any way. Regular monitoring and follow-up appointments with your doctor are essential to assess your response to the treatment and to manage any potential side effects that may arise. Open communication with your healthcare team is vital throughout your treatment journey.

How to store UNIFOLIN 50 INJECTION?Arrow

  • Keep UNIFOLIN 50MG INJ 5ML away from the reach of children and pets.
  • Store UNIFOLIN 50MG INJ 5ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of UNIFOLIN 50 INJECTIONArrow

  • UNIFOLIN 50 INJECTION serves as a vital countermeasure against medications like methotrexate, which act as folic acid antagonists. By inhibiting the dihydrofolate reductase enzyme, UNIFOLIN 50 INJECTION effectively reduces the impact of these drugs, preventing them from hindering essential metabolic processes. This is particularly crucial in scenarios where methotrexate's effects need to be mitigated.
  • Furthermore, UNIFOLIN 50 INJECTION plays a significant role in the treatment of anemia. It acts as a direct source of folic acid, an essential vitamin required for the production of healthy red blood cells. By supplementing the body's folic acid levels, UNIFOLIN 50 INJECTION helps to stimulate erythropoiesis, the process of red blood cell formation, thereby alleviating the symptoms of anemia and improving overall blood health.
  • In the context of colorectal cancer treatment, UNIFOLIN 50 INJECTION is often used in conjunction with 5-fluorouracil. It enhances the cytotoxic effects of 5-fluorouracil on cancer cells, making the chemotherapy regimen more effective. By modulating the activity of enzymes involved in DNA synthesis, UNIFOLIN 50 INJECTION helps to increase the amount of 5-fluorouracil that binds to and damages cancer cells, ultimately leading to improved treatment outcomes. It is used to increase the efficacy of 5-fluorouracil.

How to use UNIFOLIN 50 INJECTIONArrow

  • UNIFOLIN 50 INJECTION will be administered to you by a qualified physician or nurse who specializes in cancer chemotherapy. They have the expertise to handle the medication safely and effectively. Your doctor will determine the precise dosage and the length of your treatment plan. This decision is based on several crucial factors, including the specific type of cancer you have, how advanced it is (the severity), and your overall health. They will also consider other medications you might be taking and how your body is responding to the treatment.
  • The method of administration also depends on your condition. UNIFOLIN 50 INJECTION can be given intravenously, meaning directly into a vein. This allows the medication to quickly enter your bloodstream and circulate throughout your body. Alternatively, it may be administered intramuscularly, which means it's injected into a muscle. The choice between these two methods will be made by your doctor based on what is most appropriate for your individual needs and the specific characteristics of your condition. The healthcare professional administering the injection will monitor you closely for any potential side effects during and after the administration.
  • It is important to communicate openly with your medical team about any concerns or questions you may have regarding your treatment with UNIFOLIN 50 INJECTION. They are there to support you and ensure you receive the best possible care.

FAQs

Why is UNIFOLIN 50 INJECTION given 24 hours after methotrexate?Arrow

UNIFOLIN 50 INJECTION is usually administered 24 hours after methotrexate so that it does not interfere with the therapeutic effect of methotrexate. It can also be used in methotrexate overdose; it should be administered as soon as possible.

Can UNIFOLIN 50 INJECTION cause swelling?Arrow

UNIFOLIN 50 INJECTION may cause allergic reactions like rash, low blood pressure, wheezing, shortness of breath, and swelling of the face or throat.

Can UNIFOLIN 50 INJECTION cause seizures?Arrow

There is no evidence that UNIFOLIN 50 INJECTION cause seizures. But the medicine can affect the effect of seizure medication when administered concurrently. Inform your physician about all your medicines, including over-the-counter medications.

How long does it take for UNIFOLIN 50 INJECTION to work?Arrow

UNIFOLIN 50 INJECTION starts acting on the body within 5 minutes of administration. However, this might vary with respect to dosage, the patient receiving the drug, and response to treatment.

What measures should be taken to ensure the prompt excretion of methotrexate during treatment with UNIFOLIN 50 INJECTION?Arrow

A healthcare professional will monitor you during the treatment with this medicine. Maintenance of urine output above 2,500 mL/24hr in adults by increasing oral or intravenous fluids 12 hours before and for 36 hours after the end of methotrexate infusion. To monitor the alkalinization of urine (this enhances drug excretion) so that the urinary pH is greater than 7.0 before methotrexate infusion. Foods, drinks, and drugs that may increase urinary acidity should be avoided during the therapy. Finally, blood methotrexate concentration should be measured at least 24, 48, and 72 hours after the initiation of the methotrexate infusion.

NULL interaction of UNIFOLIN 50 INJECTION with other drungsArrow

There is no known interaction of UNIFOLIN 50 INJECTION with other drugs.

What advice should I follow related to UNIFOLIN 50 INJECTION?Arrow

If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking these medicinal products. Inform your doctor if you have vomited immediately after receiving the injection. If you accidentally take too much UNIFOLIN 50 INJECTION contact your doctor and seek medical advice immediately. Do not stop taking this medicine unless your doctor tells you to. Your doctor will regularly do lab tests to check the effectiveness of the medicine.

Which molecule/combination is used for making UNIFOLIN 50 INJECTION?Arrow

LEUCOVORIN CALCIUM is molecule/combination used for making UNIFOLIN 50 INJECTION.

For which ailments/diseases/conditions UNIFOLIN 50 INJECTION is prescribed?Arrow

UNIFOLIN 50 INJECTION is mainly prescribed for ailments/diseases/conditions related to Oncology.

References

Book Icon

Calcium Folinate 10 mg/ml Injection - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk. 2020

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HIGHLIGHTS OF PRESCRIBING INFORMATION [Internet].

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Pravas Ranjan Acharya

Reviewed on 24-05-2023

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(2/5)

Can get the medicines here on pocket friendly rates !

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Reviewed on 10-02-2024

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(5/5)

(Translated by Google) My experience is very good discount, if you want to give extra medicine, return to the company is also available and on time per home delivery, after 2 days of ordering, other medicines are also available if the medicine is not your pass and it is clear that it is there. itna discount available (Original) My experience is very good discount Bhi achha dete extra medicine company me return Bhi ho jati hai aur time per home delivery Bhi hoti order dene ke 2din ke ander medicine available bhi ho jati hai yadi medicine na ho unke pass and clear bolte hai ki is per itna discount milega

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Medkart is very good for generic medicines

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Medicines available at good discounted rates and it really help the pockets of the customer...even they help in getting medicines when you order and give your number ..

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Reviewed on 03-02-2024

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(5/5)


Marketer / Manufacturer Details

UNITED BIOTECH PVT LTD

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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