LEUCOKAST 50 INJECTION
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LEUCOKAST 50 INJECTION
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LEUCOKAST 50 INJECTION

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LEUCOKAST 50 INJECTION

By APRAZER HEALTHCARE PVT LTD

MRP

358

₹179

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Product DetailsArrow

About LEUCOKAST 50 INJECTION

  • LEUCOKAST 50 INJECTION contains leucovorin calcium, a substance closely related to folic acid (a vitamin). It belongs to a class of medications known as folic acid analogs. This medication plays a vital role in counteracting the harmful effects of methotrexate, a drug commonly used in cancer treatment. It is also administered to individuals who have experienced an accidental overdose of methotrexate or similar medications. Furthermore, LEUCOKAST 50 INJECTION is used in conjunction with other anticancer drugs to combat colorectal cancer, which originates in the colon or rectum. Additionally, it addresses anemia resulting from folic acid deficiency.
  • LEUCOKAST 50 INJECTION works by providing the body with a form of folic acid that can be readily used, helping to protect normal cells from the toxic effects of methotrexate. Methotrexate works by blocking an enzyme that cancer cells need to grow, but it can also affect healthy cells. Leucovorin helps to 'rescue' these healthy cells.
  • It is crucial to avoid LEUCOKAST 50 INJECTION if you have a known allergy to leucovorin calcium, calcium folinate, or any of the other ingredients in the formulation. It is also contraindicated in certain types of anemia, specifically pernicious anemia or megaloblastic anemia, where vitamin B12 levels are insufficient. Before starting treatment with LEUCOKAST 50 INJECTION, inform your doctor if you have any pre-existing conditions such as anemia, or kidney, heart, or liver problems. Disclose all medications you are currently taking, especially those used to treat seizures. Immediately notify your doctor if you experience symptoms such as wheezing or difficulty breathing, skin rashes, itching or hives, or swelling of the lips, face, or tongue, as these could indicate an allergic reaction.

Uses of LEUCOKAST 50 INJECTION

  • Management of methotrexate overdose and mitigation of its toxic effects.
  • Strategies to prevent the harmful effects of methotrexate or similar medications, aiming to reduce potential side effects and complications.
  • Treatment and management of colorectal cancer, focusing on therapeutic interventions and supportive care.
  • Addressing and treating anemia, focusing on restoring healthy red blood cell levels and overall blood health.

Side Effects of LEUCOKAST 50 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Diarrhea
  • Nausea
  • Vomiting
  • Inflamed and sore mouth
  • Tiredness
  • Allergic reactions

Safety Advice for LEUCOKAST 50 INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

There is a limited number of studies on the safety of LEUCOKAST 50 INJECTION during pregnancy, and it is unknown whether the medicine can be given during pregnancy. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.

Dosage of LEUCOKAST 50 INJECTIONArrow

  • LEUCOKAST 50 INJECTION will be administered to you by a qualified healthcare professional, such as a physician or nurse experienced in cancer chemotherapy. Your doctor will determine the appropriate dosage and treatment duration based on several factors, including the specific type and stage of your cancer, its severity, your overall health condition, and your response to the medication.
  • The method of administration, whether intravenously (into a vein) or intramuscularly (into a muscle), will also be determined by your doctor based on your individual needs and the characteristics of your condition. Intravenous administration allows the medication to enter your bloodstream directly, ensuring rapid distribution throughout your body. Intramuscular administration involves injecting the medication into a muscle, allowing for a slower, more sustained release of the drug.
  • It is crucial to adhere to the prescribed dosage and schedule provided by your healthcare team. Do not attempt to self-administer LEUCOKAST 50 INJECTION or adjust the dosage without consulting your doctor. Regular monitoring and follow-up appointments are essential to assess your progress and manage any potential side effects. Your doctor may adjust your dosage as needed based on these evaluations to optimize your treatment outcomes.

How to store LEUCOKAST 50 INJECTION?Arrow

  • Keep LEUCOKAST 50MG INJ 5ML away from the reach of children and pets.
  • Store LEUCOKAST 50MG INJ 5ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of LEUCOKAST 50 INJECTIONArrow

  • LEUCOKAST 50 INJECTION is a medication designed to mitigate the adverse effects of folic acid antagonists, such as methotrexate. These antagonists work by inhibiting the dihydrofolate reductase enzyme, which is crucial for the metabolism of folic acid. LEUCOKAST 50 INJECTION effectively counteracts this inhibition, ensuring that the body can still utilize folic acid properly.
  • In cases of anemia stemming from folic acid deficiency, LEUCOKAST 50 INJECTION serves as a vital source of folic acid. By providing the necessary folic acid, the injection supports the production of red blood cells, thereby helping to alleviate the symptoms and complications associated with anemia. This replenishment is essential for maintaining healthy oxygen transport throughout the body.
  • Furthermore, LEUCOKAST 50 INJECTION plays a significant role in the treatment of colorectal cancer. It is often used in conjunction with 5-fluorouracil, another anticancer medication. LEUCOKAST 50 INJECTION enhances the therapeutic effects of 5-fluorouracil, making the combination more effective in targeting and destroying cancer cells. This synergistic effect improves the overall outcome of the cancer treatment regimen.

How to use LEUCOKAST 50 INJECTIONArrow

  • LEUCOKAST 50 INJECTION will be administered to you by a qualified physician or nurse experienced in cancer chemotherapy. The dosage and duration of your treatment will be determined by your doctor, taking into account the specifics of your condition, its severity, and other relevant factors. It's crucial to adhere to the prescribed schedule and dosage to maximize the effectiveness of the treatment.
  • The method of administration, whether intravenously (into a vein) or intramuscularly (into a muscle), will depend on your specific medical condition and the doctor's judgment. Intravenous administration allows the medication to enter your bloodstream directly, while intramuscular injection delivers it into a muscle, from where it is absorbed into the circulation. The choice of method ensures the drug is delivered in the most effective way for your situation.
  • During the administration, the medical professionals will closely monitor you for any potential side effects or adverse reactions. It's important to inform them immediately if you experience any discomfort or unusual symptoms. Your safety and well-being are paramount throughout the treatment process. Remember to discuss any concerns you have regarding the administration or potential side effects with your doctor or nurse.

FAQs

Why is LEUCOKAST 50 INJECTION given 24 hours after methotrexate?Arrow

LEUCOKAST 50 INJECTION is usually administered 24 hours after methotrexate so that it does not interfere with the therapeutic effect of methotrexate. It can also be used in methotrexate overdose; it should be administered as soon as possible.

Can LEUCOKAST 50 INJECTION cause swelling?Arrow

LEUCOKAST 50 INJECTION may cause allergic reactions like rash, low blood pressure, wheezing, shortness of breath, and swelling of the face or throat.

Can LEUCOKAST 50 INJECTION cause seizures?Arrow

There is no evidence that LEUCOKAST 50 INJECTION cause seizures. But the medicine can affect the effect of seizure medication when administered concurrently. Inform your physician about all your medicines, including over-the-counter medications.

How long does it take for LEUCOKAST 50 INJECTION to work?Arrow

LEUCOKAST 50 INJECTION starts acting on the body within 5 minutes of administration. However, this might vary with respect to dosage, the patient receiving the drug, and response to treatment.

What measures should be taken to ensure the prompt excretion of methotrexate during treatment with LEUCOKAST 50 INJECTION?Arrow

A healthcare professional will monitor you during the treatment with this medicine. Maintenance of urine output above 2,500 mL/24hr in adults by increasing oral or intravenous fluids 12 hours before and for 36 hours after the end of methotrexate infusion. To monitor the alkalinization of urine (this enhances drug excretion) so that the urinary pH is greater than 7.0 before methotrexate infusion. Foods, drinks, and drugs that may increase urinary acidity should be avoided during the therapy. Finally, blood methotrexate concentration should be measured at least 24, 48, and 72 hours after the initiation of the methotrexate infusion.

NULL interaction of LEUCOKAST 50 INJECTION with other drungsArrow

There are no known interactions of LEUCOKAST 50 INJECTION with other drugs.

What advice should I follow regarding the use of LEUCOKAST 50 INJECTION?Arrow

If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking these medicinal products. Inform your doctor if you have vomited immediately after receiving the injection. If you accidentally take too much LEUCOKAST 50 INJECTION. contact your doctor and seek medical advice immediately. Do not stop taking this medicine unless your doctor tells you to. Your doctor will regularly do lab tests to check the effectiveness of the medicine.

What molecule/combination is used for making LEUCOKAST 50 INJECTION?Arrow

LEUCOVORIN CALCIUM is molecule/combination used for making LEUCOKAST 50 INJECTION.

For what ailments/diseases/conditions is LEUCOKAST 50 INJECTION prescribed?Arrow

LEUCOKAST 50 INJECTION is used to treat ailments/diseases/conditions in Oncology.

References

Book Icon

Calcium Folinate 10 mg/ml Injection - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk. 2020

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HIGHLIGHTS OF PRESCRIBING INFORMATION [Internet].

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Ratings & Review

Best medicine 💊

Mohit Tanna

Reviewed on 30-01-2024

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(5/5)

Geniune medicines available at good discounts

Vaishali Parikh

Reviewed on 05-12-2022

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(5/5)

Best cooperation

Chirag Patel

Reviewed on 01-02-2024

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(5/5)

Awesome experience every time i get medicine on time and they have delivery on time also staff are very cooperative and knowledgeable

Tarun Ezava

Reviewed on 22-06-2023

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(5/5)

Good service and affordable price I think best in medical

Pradeep Singh Rathore

Reviewed on 05-11-2022

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(5/5)


Marketer / Manufacturer Details

APRAZER HEALTHCARE PVT LTD

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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