LEUGET 50 INJECTION
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LEUGET 50 INJECTION
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LEUGET 50 INJECTION

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LEUGET 50 INJECTION

By GLS PHARMA LIMITED

MRP

310

₹187

39.68 % OFF

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Product DetailsArrow

About LEUGET 50 INJECTION

  • LEUGET 50 INJECTION contains leucovorin calcium, a substance related to folic acid (a vitamin). It belongs to a class of medications known as folic acid analogs. This medication is primarily used to counteract the harmful effects of methotrexate, a drug commonly used in cancer treatment. It is also administered to individuals who have experienced an accidental overdose of methotrexate or similar medications. Additionally, LEUGET 50 INJECTION is used alongside other anticancer drugs in the treatment of colorectal cancer, which originates in the colon or rectum.
  • Beyond its role in cancer therapy, LEUGET 50 INJECTION is beneficial in treating anemia resulting from folic acid deficiency. Folic acid is crucial for red blood cell production, and its deficiency can lead to various health complications. This medication helps restore healthy folic acid levels, thereby alleviating anemia symptoms and improving overall well-being.
  • Before using LEUGET 50 INJECTION, inform your healthcare provider if you have any allergies to leucovorin calcium, calcium folinate, or any other components of the medication. It is contraindicated in individuals with specific types of anemia, such as pernicious anemia or megaloblastic anemia, particularly when vitamin B12 deficiency is present. Disclose any pre-existing medical conditions, including anemia, kidney, heart, or liver problems, to your physician. Also, inform them about any medications you are currently taking, especially those for treating seizures.
  • Be vigilant for any adverse reactions while on LEUGET 50 INJECTION. Seek immediate medical attention if you experience symptoms such as wheezing, difficulty breathing, skin rash, itching, hives, or swelling of the lips, face, or tongue. These could be signs of a severe allergic reaction. Regular monitoring and open communication with your healthcare provider are essential to ensure safe and effective treatment.

Uses of LEUGET 50 INJECTION

  • Managing Methotrexate Overdose and Toxicity: Addressing the dangers of an excessive amount of methotrexate in the body, including strategies to mitigate its toxic effects.
  • Preventing the Harmful Effects of Methotrexate or Similar Medications: Taking proactive measures to safeguard against adverse reactions caused by LEUGET 50 INJECTION or drugs with comparable mechanisms.
  • Colorectal Cancer: Addressing and managing colorectal cancer, focusing on treatment options, symptom management, and supportive care strategies.
  • Anemia: Addressing Anemia, focusing on managing the condition, understanding its causes, and employing effective strategies to alleviate symptoms.

Side Effects of LEUGET 50 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, but not everyone experiences them. Common side effects include diarrhea, nausea, vomiting, an inflamed and sore mouth, and tiredness. Serious side effects may involve allergic reactions.

  • Diarrhea
  • Nausea
  • Vomiting
  • Inflammmed and sore mouth
  • Tiredness
  • Allergic reactions

Safety Advice for LEUGET 50 INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

There is a limited number of studies on the safety of LEUGET 50 INJECTION during pregnancy, and it is unknown whether the medicine can be given during pregnancy. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.

Dosage of LEUGET 50 INJECTIONArrow

  • LEUGET 50 INJECTION will be administered to you by a qualified physician or nurse specializing in cancer chemotherapy. They are trained to handle and administer such medications safely and effectively. The precise dosage and duration of your treatment will be determined by your doctor. This decision is based on a comprehensive evaluation of your individual disease condition, including the type and stage of cancer, the severity of your symptoms, and other relevant factors such as your overall health, kidney and liver function, and any other medications you may be taking. Regular monitoring and adjustments to the dosage may be necessary throughout the course of your treatment to ensure optimal effectiveness and minimize potential side effects.
  • The method of administration, whether intravenously (into a vein) or intramuscularly (into a muscle), will also be determined by your doctor based on your specific disease condition and the characteristics of LEUGET 50 INJECTION. Intravenous administration allows the medication to enter your bloodstream directly for rapid distribution throughout your body. Intramuscular injection delivers the medication into a muscle, from where it is gradually absorbed into the bloodstream. Your doctor will explain the chosen method of administration and what to expect during the procedure.
  • It's crucial to follow your doctor's instructions carefully regarding dosage and treatment schedule. Do not attempt to self-administer LEUGET 50 INJECTION or alter the prescribed dosage without consulting your doctor. Any changes to your treatment plan should be made under the guidance of a healthcare professional to ensure your safety and the effectiveness of the treatment.

How to store LEUGET 50 INJECTION?Arrow

  • Keep LEUGET 50MG INJ 5ML away from the reach of children and pets.
  • Store LEUGET 50MG INJ 5ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of LEUGET 50 INJECTIONArrow

  • LEUGET 50 INJECTION works by reversing the effects of drugs like methotrexate, which interfere with folic acid. It does this by blocking an enzyme called dihydrofolate reductase, essentially neutralizing the antagonist effects of those medications. This is vital when high doses of methotrexate are used, as LEUGET 50 INJECTION helps to protect healthy cells from the drug's toxicity.
  • Furthermore, LEUGET 50 INJECTION plays a crucial role in treating anemia, specifically when it's caused by a deficiency in folic acid. By providing the body with the necessary folic acid, it supports the production of healthy red blood cells, thereby alleviating the symptoms of anemia and improving overall well-being. It helps in cell growth and division.
  • In the treatment of colorectal cancer, LEUGET 50 INJECTION is often used in combination with 5-fluorouracil. It enhances the effectiveness of 5-fluorouracil, making it a more potent anticancer agent. LEUGET 50 INJECTION modulates the activity of 5-fluorouracil, increasing its ability to kill cancer cells. It's a synergistic approach to cancer therapy, maximizing the therapeutic impact while minimizing potential side effects.

How to use LEUGET 50 INJECTIONArrow

  • LEUGET 50 INJECTION is administered by a qualified healthcare professional, such as a physician or nurse who is specifically trained in cancer chemotherapy. This ensures the safe and effective delivery of the medication.
  • The dosage and duration of your treatment will be determined by your doctor, taking into account several key factors, including the type and stage of your cancer, the severity of your condition, your overall health, and how well you respond to the medication. This personalized approach is crucial for optimizing the effectiveness of the treatment while minimizing potential side effects.
  • LEUGET 50 INJECTION can be administered either intravenously (directly into a vein) or intramuscularly (into a muscle). The route of administration will be determined by your doctor based on the specific characteristics of your disease and the best way to ensure the medication reaches the affected areas effectively. Your healthcare provider will explain the chosen method to you in detail.
  • It's important to adhere to the prescribed treatment schedule and attend all scheduled appointments. Consistent and timely administration of LEUGET 50 INJECTION is essential for achieving the best possible outcome. If you have any questions or concerns about your treatment, don't hesitate to discuss them with your doctor or nurse.
  • During the administration of LEUGET 50 INJECTION, you will be closely monitored for any potential side effects or adverse reactions. This allows the healthcare team to address any issues promptly and ensure your comfort and safety throughout the treatment process.

FAQs

<p>Why is LEUGET 50 INJECTION given 24 hours after methotrexate?</p>Arrow

LEUGET 50 INJECTION is usually administered 24 hours after methotrexate so that it does not interfere with the therapeutic effect of methotrexate. It can also be used in methotrexate overdose; it should be administered as soon as possible.

<p>Can LEUGET 50 INJECTION cause swelling?</p>Arrow

LEUGET 50 INJECTION may cause allergic reactions like rash, low blood pressure, wheezing, shortness of breath, and swelling of the face or throat.

<p>Can LEUGET 50 INJECTION cause seizures?</p>Arrow

There is no evidence that LEUGET 50 INJECTION cause seizures. But the medicine can affect the effect of seizure medication when administered concurrently. Inform your physician about all your medicines, including over-the-counter medications.

<p>How long does it take for LEUGET 50 INJECTION to work?</p>Arrow

LEUGET 50 INJECTION starts acting on the body within 5 minutes of administration. However, this might vary with respect to dosage, the patient receiving the drug, and response to treatment.

<p>What measures should be taken to ensure the prompt excretion of methotrexate during treatment with LEUGET 50 INJECTION?</p>Arrow

A healthcare professional will monitor you during the treatment with this medicine. Maintenance of urine output above 2,500 mL/24hr in adults by increasing oral or intravenous fluids 12 hours before and for 36 hours after the end of methotrexate infusion. To monitor the alkalinization of urine (this enhances drug excretion) so that the urinary pH is greater than 7.0 before methotrexate infusion. Foods, drinks, and drugs that may increase urinary acidity should be avoided during the therapy. Finally, blood methotrexate concentration should be measured at least 24, 48, and 72 hours after the initiation of the methotrexate infusion.

NULL interaction of LEUGET 50 INJECTION with other drungsArrow

There is NULL interaction of LEUGET 50 INJECTION with other drugs.

<p>If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking these medicinal products. Inform your doctor if you have vomited immediately after receiving the injection. If you accidentally take too much LEUGET 50 INJECTION. contact your doctor and seek medical advice immediately. Do not stop taking this medicine unless your doctor tells you to. Your doctor will regularly do lab tests to check the effectiveness of the medicine.&nbsp;</p> is an advice related to LEUGET 50 INJECTIONArrow

If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking these medicinal products. Inform your doctor if you have vomited immediately after receiving the injection. If you accidentally take too much LEUGET 50 INJECTION. contact your doctor and seek medical advice immediately. Do not stop taking this medicine unless your doctor tells you to. Your doctor will regularly do lab tests to check the effectiveness of the medicine. 

What is LEUGET 50 INJECTION made of?Arrow

LEUGET 50 INJECTION is made of LEUCOVORIN CALCIUM.

What ailments/diseases/conditions is LEUGET 50 INJECTION prescribed for?Arrow

LEUGET 50 INJECTION is prescribed for Oncology.

References

Book Icon

Calcium Folinate 10 mg/ml Injection - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk. 2020

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HIGHLIGHTS OF PRESCRIBING INFORMATION [Internet].

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Marketer / Manufacturer Details

GLS PHARMA LIMITED

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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