LEUTERO 50MG/5ML INJECTION
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LEUTERO 50MG/5ML INJECTION
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LEUTERO 50MG/5ML INJECTION

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LEUTERO 50MG/5ML INJECTION

By HETERO HEALTHCARE LTD

MRP

₹

275

₹77

72 % OFF

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Product DetailsArrow

About LEUTERO 50MG/5ML INJECTION

  • LEUTERO 50MG/5ML INJECTION contains leucovorin calcium, a substance closely related to folic acid, a vital vitamin. As a folic acid analog, it plays a crucial role in mitigating the adverse effects of methotrexate, a powerful medication used in cancer treatment. Specifically, it's administered to counteract methotrexate's harmful effects during cancer therapy. Furthermore, LEUTERO 50MG/5ML INJECTION serves as an antidote for individuals who have experienced a methotrexate overdose or have taken similar medications inadvertently. Its application extends to colorectal cancer treatment (cancer affecting the colon or rectum), where it's employed alongside other anticancer drugs to enhance their efficacy. In some cases, it's also prescribed to address anemia stemming from folic acid deficiency.
  • This medication's primary function is to rescue healthy cells from the toxic effects of methotrexate, allowing for higher doses of methotrexate to be used, thus improving cancer treatment outcomes. It is important to remember that LEUTERO 50MG/5ML INJECTION is not a chemotherapy drug itself, but rather a protective agent that helps to minimize damage to normal tissues. The dosage and timing of LEUTERO 50MG/5ML INJECTION are critical and must be carefully followed as prescribed by your healthcare provider.
  • It is important to avoid LEUTERO 50MG/5ML INJECTION if you have a known allergy to leucovorin calcium, calcium folinate, or any other components of the formulation. It is also contraindicated in individuals with specific types of anemia, such as pernicious anemia or megaloblastic anemia, resulting from vitamin B12 deficiency. Before starting treatment with LEUTERO 50MG/5ML INJECTION, be sure to inform your doctor if you have any pre-existing medical conditions, including anemia, kidney problems, heart conditions, or liver disorders. Alert your physician if you are currently taking any medications to manage seizures, as leucovorin can interact with these drugs. Seek immediate medical attention if you experience any signs of an allergic reaction, such as wheezing or difficulty breathing, skin rashes, itching, hives, or swelling of the lips, face, or tongue.

Uses of LEUTERO 50MG/5ML INJECTION

  • Addressing Methotrexate Overdose and Toxicity: Understanding the Risks and Management
  • Preventing the Harmful Effects of Methotrexate or Similar Medications: Protective Measures and Strategies
  • Colorectal Cancer: Understanding, Managing, and Treating Cancer of the Colon and Rectum
  • Anemia: Addressing the Causes, Symptoms, and Treatments for Iron Deficiency

Side Effects of LEUTERO 50MG/5ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. With LEUTERO 50MG/5ML INJECTION you may experience common side effects like diarrhea, nausea, vomiting, an inflamed and sore mouth, and tiredness. Serious side effects could include allergic reactions.

  • Diarrhea
  • Nausea
  • Vomiting
  • Inflammmed and sore mouth
  • Tiredness
  • Allergic reactions

Safety Advice for LEUTERO 50MG/5ML INJECTIONArrow

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Pregnancy

CONSULT YOUR DOCTOR

There is a limited number of studies on the safety of LEUTERO 50MG/5ML INJECTION during pregnancy, and it is unknown whether the medicine can be given during pregnancy. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.

Dosage of LEUTERO 50MG/5ML INJECTIONArrow

  • A qualified healthcare professional, such as a physician or nurse specializing in cancer chemotherapy, will administer LEUTERO 50MG/5ML INJECTION to you. This ensures the drug is given safely and effectively, with close monitoring for any immediate reactions.
  • Your doctor will carefully determine the appropriate dosage and the length of your treatment. This decision is based on a thorough assessment of your individual disease condition, its severity, and other relevant factors, such as your overall health and any other medications you may be taking. The goal is to find the most effective dose that minimizes potential side effects.
  • LEUTERO 50MG/5ML INJECTION is typically administered either intravenously (directly into a vein) or intramuscularly (directly into a muscle). The specific route of administration will depend on your individual disease condition and the doctor's judgment. Intravenous administration allows the medication to enter the bloodstream quickly, while intramuscular injection provides a slower, more sustained release.
  • Throughout your treatment, your healthcare team will closely monitor your progress and adjust the dosage as needed to ensure the best possible outcome.

How to store LEUTERO 50MG/5ML INJECTION?Arrow

  • Keep LEUTERO 50MG INJ 5ML away from the reach of children and pets.
  • Store LEUTERO 50MG INJ 5ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of LEUTERO 50MG/5ML INJECTIONArrow

  • LEUTERO 50MG/5ML INJECTION works by interfering with the action of dihydrofolate reductase, an enzyme crucial for cell growth and replication. This interference is particularly important when patients are taking medications like methotrexate, which are folic acid antagonists. By inhibiting this enzyme, LEUTERO 50MG/5ML INJECTION can counteract the negative effects of these drugs, preventing them from depleting folate levels excessively. This is vital for patients undergoing chemotherapy or taking medications that impact folate metabolism.
  • Furthermore, LEUTERO 50MG/5ML INJECTION provides a source of folic acid, which is essential for the production of red blood cells. When the body lacks sufficient folic acid, it can lead to anemia, a condition characterized by a deficiency in red blood cells. By supplementing with folic acid, LEUTERO 50MG/5ML INJECTION helps to ensure that the body has the necessary building blocks to create healthy red blood cells, thus preventing or treating anemia.
  • In the treatment of colorectal cancer, LEUTERO 50MG/5ML INJECTION is often used in conjunction with 5-fluorouracil (5-FU). It enhances the effectiveness of 5-FU by modulating its effects on cancer cells. Specifically, LEUTERO 50MG/5ML INJECTION helps 5-FU bind more tightly to its target enzyme in cancer cells, leading to a more potent anti-cancer effect. This combination therapy can significantly improve outcomes for patients with colorectal cancer.

How to use LEUTERO 50MG/5ML INJECTIONArrow

  • LEUTERO 50MG/5ML INJECTION will be administered to you by a trained physician or nurse who specializes in cancer chemotherapy. They have the expertise to handle the drug safely and manage any potential side effects that may arise. Your doctor will carefully determine the appropriate dose and duration of treatment based on several factors, including the type and stage of your cancer, its severity, and your overall health condition. It's crucial to adhere to the prescribed treatment schedule for the best possible outcome.
  • The medication is administered either intravenously, directly into your vein, or intramuscularly, into your muscle. The specific route of administration will depend on your individual disease condition and the characteristics of the drug. Intravenous administration allows the medication to enter your bloodstream directly, ensuring rapid distribution throughout your body. Intramuscular injections, on the other hand, allow for a slower, more sustained release of the drug.
  • Throughout your treatment, the medical team will closely monitor your progress and adjust the dosage or administration method as needed to optimize the effectiveness of LEUTERO 50MG/5ML INJECTION and minimize any potential adverse reactions. It's important to communicate openly with your doctor and nurses about any concerns or side effects you may be experiencing. They are there to support you throughout your cancer journey and ensure you receive the best possible care.

FAQs

Why is LEUTERO 50MG/5ML INJECTION given 24 hours after methotrexate?Arrow

LEUTERO 50MG/5ML INJECTION is usually administered 24 hours after methotrexate so that it does not interfere with the therapeutic effect of methotrexate. It can also be used in methotrexate overdose; it should be administered as soon as possible.

Can LEUTERO 50MG/5ML INJECTION cause swelling?Arrow

LEUTERO 50MG/5ML INJECTION may cause allergic reactions like rash, low blood pressure, wheezing, shortness of breath, and swelling of the face or throat.

Can LEUTERO 50MG/5ML INJECTION cause seizures?Arrow

There is no evidence that LEUTERO 50MG/5ML INJECTION cause seizures. But the medicine can affect the effect of seizure medication when administered concurrently. Inform your physician about all your medicines, including over-the-counter medications.

How long does it take for LEUTERO 50MG/5ML INJECTION to work?Arrow

LEUTERO 50MG/5ML INJECTION starts acting on the body within 5 minutes of administration. However, this might vary with respect to dosage, the patient receiving the drug, and response to treatment.

What measures should be taken to ensure the prompt excretion of methotrexate during treatment with LEUTERO 50MG/5ML INJECTION?Arrow

A healthcare professional will monitor you during the treatment with this medicine. Maintenance of urine output above 2,500 mL/24hr in adults by increasing oral or intravenous fluids 12 hours before and for 36 hours after the end of methotrexate infusion. To monitor the alkalinization of urine (this enhances drug excretion) so that the urinary pH is greater than 7.0 before methotrexate infusion. Foods, drinks, and drugs that may increase urinary acidity should be avoided during the therapy. Finally, blood methotrexate concentration should be measured at least 24, 48, and 72 hours after the initiation of the methotrexate infusion.

Does LEUTERO 50MG/5ML INJECTION interact with other drugs?Arrow

There is no known interaction of LEUTERO 50MG/5ML INJECTION with other drugs.

What advice should I follow while taking LEUTERO 50MG/5ML INJECTION?Arrow

If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking these medicinal products. Inform your doctor if you have vomited immediately after receiving the injection. If you accidentally take too much LEUTERO 50MG/5ML INJECTION, contact your doctor and seek medical advice immediately. Do not stop taking this medicine unless your doctor tells you to. Your doctor will regularly do lab tests to check the effectiveness of the medicine.

What molecule/combination is used for making LEUTERO 50MG/5ML INJECTION?Arrow

LEUCOVORIN CALCIUM is the molecule/combination used for making LEUTERO 50MG/5ML INJECTION.

For what ailments/diseases/conditions is LEUTERO 50MG/5ML INJECTION prescribed?Arrow

LEUTERO 50MG/5ML INJECTION is prescribed for ailments/diseases/conditions related to Oncology.

References

Book Icon

Calcium Folinate 10 mg/ml Injection - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk. 2020

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HIGHLIGHTS OF PRESCRIBING INFORMATION [Internet].

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Marketer / Manufacturer Details

HETERO HEALTHCARE LTD

Country of Origin -

India

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LEUTERO 50MG/5ML INJECTION

LEUTERO 50MG/5ML INJECTION

MRP

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275

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72 % OFF

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