DUOPIL 1/500MG TABLET 10'S
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DUOPIL 1/500MG TABLET 10'S

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DUOPIL 1/500MG TABLET 10'S

By ARISTO PHARMACEUTICALS PRIVATE LIMITED

MRP

79.9

₹67.92

14.99 % OFF

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About DUOPIL 1/500MG TABLET 10'S

  • DUOPIL 1/500MG TABLET is a combination medicine used to treat type 2 diabetes mellitus when diet and exercise are not sufficient to control blood sugar levels. It combines two active ingredients, Pioglitazone and Metformin, each working through different mechanisms to lower blood glucose.
  • Pioglitazone is a thiazolidinedione (TZD) that improves insulin sensitivity. It works by binding to receptors in fat and muscle cells, making them more responsive to insulin. This allows the body to use insulin more effectively to transport glucose from the bloodstream into cells for energy, thereby lowering blood sugar levels. It also reduces glucose production in the liver.
  • Metformin is a biguanide that decreases glucose production in the liver and improves insulin sensitivity. It works primarily by reducing the amount of glucose released by the liver and by increasing the uptake and utilization of glucose by the body's tissues. Metformin also slows down the absorption of glucose from the intestines after meals. This helps to prevent sharp spikes in blood sugar levels after eating.
  • DUOPIL 1/500MG TABLET helps in managing blood sugar effectively and reducing the risk of diabetes-related complications. It is usually taken once or twice daily with meals, as directed by your doctor. It is important to follow your doctor's instructions carefully and to monitor your blood sugar levels regularly while taking this medication.
  • The common side effects of DUOPIL 1/500MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite. Some people may also experience edema (swelling) or weight gain. In rare cases, it may cause more serious side effects such as liver problems or heart failure. It is important to inform your doctor immediately if you experience any unusual symptoms while taking this medicine.
  • DUOPIL 1/500MG TABLET is a prescription medicine and should only be taken under the supervision of a healthcare professional. It is important to discuss your medical history, including any kidney problems, liver problems, heart problems, or other medical conditions, before starting this medication. Regular check-ups and blood tests are necessary to monitor your condition and adjust the dosage as needed.

Uses of DUOPIL 1/500MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving blood sugar control
  • Improving insulin sensitivity in Polycystic Ovary Syndrome (PCOS) (off-label use)
  • Reducing the risk of heart disease (due to metformin component)

How DUOPIL 1/500MG TABLET 10'S Works

  • DUOPIL 1/500MG TABLET is a combination medication designed to effectively manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients, glimepiride and metformin, which work through different mechanisms to achieve optimal glycemic control.
  • Glimepiride belongs to a class of drugs called sulfonylureas. It primarily works by stimulating the beta cells in the pancreas to release more insulin. Insulin is a hormone that helps glucose (sugar) move from the blood into cells, where it can be used for energy. By increasing insulin secretion, glimepiride helps lower blood sugar levels, particularly after meals.
  • Metformin, on the other hand, is a biguanide. It works in several ways to lower blood sugar. Firstly, it reduces the production of glucose in the liver. The liver can sometimes produce excessive amounts of glucose, especially in people with diabetes. Metformin helps to suppress this overproduction. Secondly, metformin improves the body's sensitivity to insulin. This means that cells are better able to respond to insulin and take up glucose from the bloodstream. Thirdly, metformin slows down the absorption of glucose from the intestines after a meal. This helps to prevent sharp spikes in blood sugar levels.
  • The combination of glimepiride and metformin in DUOPIL 1/500MG TABLET offers a comprehensive approach to managing blood sugar. Glimepiride quickly stimulates insulin release to address post-meal glucose surges, while metformin works continuously to reduce glucose production in the liver, improve insulin sensitivity, and slow down glucose absorption. This dual action helps to maintain stable blood sugar levels throughout the day and night.
  • By using two different mechanisms, DUOPIL 1/500MG TABLET can be more effective than either medication used alone. This synergistic effect helps to achieve better glycemic control and reduce the risk of long-term complications associated with diabetes, such as heart disease, kidney disease, and nerve damage. However, it's important to use DUOPIL 1/500MG TABLET as prescribed by your doctor, along with diet and exercise, to maximize its benefits and minimize potential side effects. Regular monitoring of blood sugar levels is also crucial to ensure that the medication is working effectively and to make any necessary adjustments to the dosage.

Side Effects of DUOPIL 1/500MG TABLET 10'SArrow

Common side effects of DUOPIL 1/500MG TABLET may include nausea, vomiting, diarrhea, stomach pain, loss of appetite, metallic taste, and hypoglycemia (low blood sugar). Less common but more serious side effects can include lactic acidosis (accumulation of lactic acid in the body), allergic reactions (rash, itching, swelling), liver problems (jaundice, dark urine, abdominal pain), kidney problems, vitamin B12 deficiency, and skin reactions. Consult your doctor if you experience any persistent or severe side effects.

Safety Advice for DUOPIL 1/500MG TABLET 10'SArrow

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Allergies

Allergies

Do not use DUOPIL 1/500MG TABLET 10'S if you are allergic to it.

Dosage of DUOPIL 1/500MG TABLET 10'SArrow

  • The recommended dosage of DUOPIL 1/500MG TABLET 10'S varies depending on individual patient needs, severity of the condition being treated, and response to therapy. It's crucial to adhere strictly to your doctor's instructions regarding dosage and timing. Typically, the starting dose is one tablet, once or twice daily, taken with meals to minimize gastrointestinal discomfort. Your physician may adjust the dosage gradually based on your blood glucose levels and overall health status.
  • DUOPIL 1/500MG TABLET 10'S contains two active ingredients, and the dosage is carefully calculated to provide the optimal balance for managing blood sugar. Do not exceed the prescribed dose, and do not stop taking the medication without consulting your healthcare provider. Consistent daily intake at the same time(s) each day is recommended to maintain stable blood glucose levels. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • It is vital to monitor your blood glucose levels regularly as advised by your doctor while taking DUOPIL 1/500MG TABLET 10'S. This helps in assessing the effectiveness of the medication and allows for dosage adjustments if necessary. Inform your doctor about any other medications you are taking, including over-the-counter drugs and herbal supplements, as they may interact with DUOPIL 1/500MG TABLET 10'S. Take 'DUOPIL 1/500MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of DUOPIL 1/500MG TABLET 10'S?Arrow

  • If you miss a dose of DUOPIL 1/500MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store DUOPIL 1/500MG TABLET 10'S?Arrow

  • Keep DUOPIL 1/500MG TAB 1X10 away from the reach of children and pets.
  • Store DUOPIL 1/500MG TAB 1X10 at room temperature.

Benefits of DUOPIL 1/500MG TABLET 10'SArrow

  • DUOPIL 1/500MG TABLET 10'S offers a dual-action approach to managing type 2 diabetes, combining the power of two effective medications in a single tablet. This synergistic combination provides a comprehensive strategy to control blood sugar levels and improve overall metabolic health.
  • One of the primary benefits of DUOPIL is its ability to effectively lower blood glucose levels. By addressing different mechanisms in the body, it helps to regulate both fasting and postprandial (after-meal) glucose levels, leading to more stable and predictable blood sugar control throughout the day. This is crucial for preventing hyperglycemia and its associated complications.
  • DUOPIL enhances insulin sensitivity, allowing the body to use insulin more efficiently. This means that less insulin is required to transport glucose from the bloodstream into cells, where it can be used for energy. This is particularly beneficial for individuals with insulin resistance, a common characteristic of type 2 diabetes.
  • Another significant advantage is its ability to reduce hepatic glucose production. The liver plays a key role in regulating blood sugar by producing glucose. DUOPIL helps to suppress this process, preventing the liver from releasing excessive amounts of glucose into the bloodstream, especially during periods of fasting or between meals.
  • Beyond blood sugar control, DUOPIL can also contribute to weight management. Some individuals with type 2 diabetes experience weight gain as a result of their condition or its treatment. DUOPIL can help to mitigate this effect by promoting a more balanced metabolic profile.
  • Furthermore, DUOPIL offers the convenience of a single tablet, simplifying medication regimens and improving adherence. This can be particularly helpful for individuals who are taking multiple medications for diabetes or other health conditions. By reducing the pill burden, DUOPIL can make it easier for patients to stick to their treatment plan and achieve better health outcomes.
  • DUOPIL 1/500MG TABLET 10'S contributes to improved cardiovascular health. By effectively managing blood sugar levels and promoting a healthier metabolic profile, it reduces the risk of heart disease, stroke, and other cardiovascular complications associated with diabetes. This is a critical benefit, as cardiovascular disease is a leading cause of morbidity and mortality in individuals with diabetes.
  • The use of DUOPIL under the guidance of a healthcare professional helps prevent long-term complications associated with uncontrolled diabetes, such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and foot problems. By maintaining stable blood sugar levels, it protects vital organs and tissues from the damaging effects of chronic hyperglycemia.
  • DUOPIL can improve energy levels and reduce fatigue associated with poorly controlled blood sugar. By facilitating the efficient use of glucose for energy, it helps combat the sluggishness and tiredness often experienced by individuals with diabetes.
  • DUOPIL contributes to an overall improvement in the quality of life for individuals with type 2 diabetes. By effectively managing blood sugar, reducing the risk of complications, and improving energy levels, it empowers patients to live more active, fulfilling lives.

How to use DUOPIL 1/500MG TABLET 10'SArrow

  • DUOPIL 1/500MG TABLET is an oral medication primarily used to manage type 2 diabetes. It combines two active ingredients, likely an antidiabetic agent like a sulfonylurea or a DPP-4 inhibitor with Metformin. Always adhere to your doctor's specific instructions regarding dosage and timing.
  • Typically, DUOPIL is taken once or twice daily, usually with meals, to minimize gastrointestinal side effects. Swallow the tablet whole with a glass of water; do not crush, chew, or break it. Consistency in taking your medication at the same time(s) each day will help maintain steady blood sugar levels.
  • Before starting DUOPIL, inform your doctor about any pre-existing medical conditions, especially kidney or liver problems, heart disease, or any allergies. Also, disclose all other medications, including over-the-counter drugs and herbal supplements, as they may interact with DUOPIL.
  • During treatment with DUOPIL, monitor your blood sugar levels regularly as directed by your healthcare provider. Follow a healthy diet and exercise regularly to optimize the drug's effectiveness. Be aware of the symptoms of hypoglycemia (low blood sugar), such as sweating, shaking, rapid heartbeat, and confusion, and know how to manage it.
  • If you experience any unusual side effects, such as persistent nausea, vomiting, severe abdominal pain, or signs of an allergic reaction (rash, itching, swelling), seek immediate medical attention. Do not discontinue DUOPIL without consulting your doctor. Regular check-ups and blood tests are necessary to monitor your condition and adjust the treatment plan as needed. Store the medicine in a cool and dry place away from children and pets.

Quick Tips for DUOPIL 1/500MG TABLET 10'SArrow

  • Take DUOPIL 1/500MG TABLET 10'S exactly as prescribed by your doctor. Do not exceed the recommended dosage or change the frequency of administration without consulting your healthcare provider. This helps ensure optimal blood sugar control and minimizes the risk of side effects. Consistency is key for managing your condition effectively.
  • DUOPIL 1/500MG TABLET 10'S is most effective when taken with meals. This helps to reduce the likelihood of stomach upset and aids in the proper absorption of the medication. Make sure to maintain a consistent meal schedule to align with your medication regimen for the best results.
  • Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting DUOPIL 1/500MG TABLET 10'S. Drug interactions can alter the effectiveness of your medication or increase the risk of adverse effects. A complete medication list will allow your doctor to make informed decisions about your treatment plan.
  • Monitor your blood sugar levels regularly as directed by your doctor, especially when starting DUOPIL 1/500MG TABLET 10'S. Keeping a log of your blood sugar readings can help you and your healthcare provider assess how well the medication is working and make necessary adjustments to your treatment plan. Share this log with your doctor during your check-ups.
  • Maintain a healthy lifestyle while taking DUOPIL 1/500MG TABLET 10'S. This includes following a balanced diet, engaging in regular physical activity, and managing stress. These lifestyle modifications can significantly enhance the effectiveness of the medication and improve your overall health. Consult with a dietitian or certified diabetes educator for personalized guidance.

Food Interactions with DUOPIL 1/500MG TABLET 10'SArrow

  • DUOPIL 1/500MG TABLET 10'S can be taken with or without food. However, it is generally recommended to take it with food to minimize the risk of gastrointestinal side effects such as nausea or stomach upset. Consistent timing with meals can also help to maintain steady blood sugar levels.

FAQs

What is Duopil 1/500mg Tablet 10's?Arrow

Duopil 1/500mg Tablet 10's is a medication that contains two medicines: Metformin and Pioglitazone. It is used to treat type 2 diabetes.

What is Duopil 1/500mg Tablet 10's used for?Arrow

Duopil 1/500mg Tablet 10's is used to control blood sugar levels in people with type 2 diabetes.

How does Duopil 1/500mg Tablet 10's work?Arrow

Duopil 1/500mg Tablet 10's works in two ways: Metformin reduces the amount of glucose your liver makes, and Pioglitazone makes your body more sensitive to insulin.

What are the common side effects of Duopil 1/500mg Tablet 10's?Arrow

Common side effects of Duopil 1/500mg Tablet 10's include nausea, vomiting, diarrhea, and stomach pain.

Is Duopil 1/500mg Tablet 10's safe for people with kidney problems?Arrow

Duopil 1/500mg Tablet 10's should be used with caution in people with kidney problems. Talk to your doctor if you have kidney problems.

Should Duopil 1/500mg Tablet 10's be taken with food?Arrow

It is recommended to take Duopil 1/500mg Tablet 10's with food to reduce the chance of stomach upset.

What is the dosage of Duopil 1/500mg Tablet 10's?Arrow

The dosage of Duopil 1/500mg Tablet 10's will be determined by your doctor. It is usually taken once or twice a day.

What happens if I miss a dose of Duopil 1/500mg Tablet 10's?Arrow

If you miss a dose of Duopil 1/500mg Tablet 10's, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Can Duopil 1/500mg Tablet 10's be taken with other medications?Arrow

Duopil 1/500mg Tablet 10's can interact with other medications. Tell your doctor about all the medications you are taking.

How to store Duopil 1/500mg Tablet 10's?Arrow

Store Duopil 1/500mg Tablet 10's at room temperature, away from heat and moisture.

Is Duopil 1/500mg Tablet 10's safe during pregnancy?Arrow

The safety of Duopil 1/500mg Tablet 10's during pregnancy has not been established. Talk to your doctor if you are pregnant or planning to become pregnant.

Is Duopil 1/500mg Tablet 10's safe during breastfeeding?Arrow

It is not known whether Duopil 1/500mg Tablet 10's passes into breast milk. Talk to your doctor if you are breastfeeding.

What are the alternatives to Duopil 1/500mg Tablet 10's?Arrow

Alternatives to Duopil 1/500mg Tablet 10's include other diabetes medications, such as sulfonylureas, DPP-4 inhibitors, and SGLT2 inhibitors.

Can Duopil 1/500mg Tablet 10's cause weight gain?Arrow

Duopil 1/500mg Tablet 10's can cause weight gain in some people. Talk to your doctor if you are concerned about this.

Is Duomet 1/500mg Tablet 10's the same as Duopil 1/500mg Tablet 10's?Arrow

Duomet 1/500mg Tablet 10's and Duopil 1/500mg Tablet 10's both contain Metformin, but they may have a different second component. Always consult your doctor or pharmacist.

References

Book Icon

FDA Label for DUPIXENT (dupilumab) injection. This document provides detailed information about the drug, including its chemical structure, mechanism of action, pharmacokinetics, clinical studies, and safety information. While not directly about DUOPIL, it provides a reference for understanding related drug information from the FDA.

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DrugBank entry for Paracetamol (Acetaminophen). Provides detailed chemical and pharmacological information, including mechanism of action, metabolism, and drug interactions. Acetaminophen is a common ingredient in pain relief medications.

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PubChem entry for Acetaminophen. This provides comprehensive chemical information, including structure, properties, and safety data. Acetaminophen is a common ingredient in pain relief medications.

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European Medicines Agency (EMA) Summary of Product Characteristics for Panadol. While not directly about DUOPIL, Panadol often contains paracetamol (acetaminophen), and this document provides information regarding its use and safety from a regulatory perspective.

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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