ENFIERA 100 INJECTION
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ENFIERA 100 INJECTION
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ENFIERA 100 INJECTION

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ENFIERA 100 INJECTION

By ZYDUS LIFESCIENCES LIMITED

MRP

8700

₹5220

40 % OFF

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Composition

Product DetailsArrow

About ENFIERA 100 INJECTION

  • ENFIERA 100 INJECTION contains rituximab as its active ingredient. It is prescribed for various conditions in adults, either alone or in conjunction with other medications. These conditions include non-Hodgkin's lymphoma, a cancer affecting B-lymphocytes (a type of white blood cell), and chronic lymphocytic leukemia, a common cancer affecting B-cells. Additionally, it's used with methotrexate to treat moderate-to-severe rheumatoid arthritis, an autoimmune disease where the immune system attacks joint tissues. ENFIERA 100 INJECTION is also indicated for granulomatosis with polyangiitis and microscopic polyangiitis, inflammatory conditions of blood vessels primarily affecting the lungs and kidneys in adults and children aged 2 years and older. Furthermore, it serves as a treatment for moderate to severe pemphigus vulgaris, an autoimmune disorder causing painful blisters on the skin and mucous membranes.
  • ENFIERA 100 INJECTION is classified as an anti-CD20 monoclonal antibody. Avoid this injection if you are allergic to rituximab or any of its components, have a compromised immune system, or suffer from a severe active infection. Before starting treatment, inform your doctor about any pre-existing heart conditions, heart failure, or breathing difficulties. Disclose any history of hepatitis B infection to your doctor, as rituximab can reactivate the virus, potentially leading to severe complications. It is strongly advised to avoid pregnancy and breastfeeding while undergoing treatment with this injection. Discuss alternative options with your healthcare provider if necessary.
  • Common side effects of ENFIERA 100 INJECTION may include blood infections, reduced red blood cell count, dizziness, facial and bodily swelling, skin itching, diarrhea, increased sweating, and fluctuations in blood pressure. If you are capable of becoming pregnant, utilize effective contraception during treatment and for 12 months following the final dose. This medication can trigger severe infusion reactions during or within 24 hours of administration. Immediately notify your doctor or healthcare professional if you experience any infusion-related symptoms, such as elevated blood pressure, chest pain, headache, breathing problems, vomiting, skin rashes, or throat swelling. Regular monitoring during and after the infusion is crucial to manage potential reactions promptly.

Uses of ENFIERA 100 INJECTION

  • Non-Hodgkin's Lymphoma (NHL), a type of cancer that begins in the lymphatic system, impacting the white blood cells called lymphocytes.
  • Chronic Lymphocytic Leukemia (CLL), a type of cancer of the blood and bone marrow that progresses slowly, affecting the lymphocytes.
  • Rheumatoid Arthritis, a chronic inflammatory disorder affecting many joints, including those in the hands and feet, causing pain, swelling, and stiffness.
  • Granulomatosis with Polyangiitis or Microscopic Polyangiitis, rare autoimmune diseases that cause inflammation of blood vessels, affecting organs like the lungs and kidneys.
  • Pemphigus Vulgaris, a rare autoimmune disorder that causes painful blisters on the skin and mucous membranes, such as in the mouth and nose.

Side Effects of ENFIERA 100 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, though not everyone experiences them. Common side effects include:

  • Swelling in the face and body
  • Diarrhea and nausea
  • Itchy skin
  • Anemia
  • Muscle spasm
  • Headache
  • Urinary tract infection
  • Fever, chills, and shivering
  • Inflammation of nasal cavities
  • Cough, sore throat
  • Loss of hair
  • Increased or decreased blood pressure
  • Chest pain
  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Memory loss, trouble thinking, difficulty in walking

Safety Advice for ENFIERA 100 INJECTIONArrow

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Pregnancy

UNSAFE

ENFIERA 100 INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of ENFIERA 100 INJECTIONArrow

  • ENFIERA 100 INJECTION must be administered strictly by a qualified healthcare professional, such as a doctor or nurse, experienced in administering intravenous infusions. Self-administration is strictly prohibited. Prior to receiving ENFIERA 100 INJECTION, you will be given pre-medications to help minimize potential side effects. These pre-medications might include antihistamines, corticosteroids, or other medications as deemed necessary by your doctor.
  • The dosage and duration of treatment with ENFIERA 100 INJECTION will be determined by your doctor based on several factors, including the severity of your condition, your overall health, and your response to treatment. It is crucial to adhere to the prescribed dosage and treatment schedule provided by your healthcare provider for optimal results.
  • ENFIERA 100 INJECTION is administered as an intravenous infusion, meaning it is delivered directly into your vein over a specific period. During the infusion, you will be closely monitored by medical personnel for any signs of adverse reactions or side effects. This close monitoring allows for prompt intervention if any issues arise.

How to store ENFIERA 100 INJECTION?Arrow

  • Keep ENFIERA 100MG INJ away from the reach of children and pets.
  • Store ENFIERA 100MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of ENFIERA 100 INJECTIONArrow

  • ENFIERA 100 INJECTION is a specialized medication classified as a monoclonal antibody. It is designed to specifically target the CD20 antigen, which is present on the surface of B-lymphocytes. B-lymphocytes are a crucial type of white blood cell involved in the immune response.
  • The primary mechanism of action of ENFIERA 100 INJECTION involves binding to these B-cells. Once bound, it triggers cell death, a process particularly beneficial in treating Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL), where abnormal B-cell proliferation occurs. This targeted approach helps to reduce the number of cancerous B-cells.
  • Beyond inducing cell death, the binding action of ENFIERA 100 INJECTION also inhibits B-cell activation and subsequent growth. This blockage contributes to its anticancer effects by preventing the further expansion of malignant B-cell populations. The drug’s action extends beyond cancer treatment; it also plays a role in managing rheumatoid arthritis.
  • In the context of rheumatoid arthritis, ENFIERA 100 INJECTION inhibits the production of rheumatoid factor, a key marker of the disease. Additionally, it interferes with antigen presentation, T-cell activation, and the production of pro-inflammatory cytokines. By modulating these immune processes, it helps to reduce inflammation and alleviate the symptoms associated with rheumatoid arthritis.
  • Therefore, ENFIERA 100 INJECTION serves a dual purpose: it directly targets and eliminates cancerous B-cells in NHL and CLL, and it modulates the immune system to reduce inflammation and disease activity in rheumatoid arthritis.

How to use ENFIERA 100 INJECTIONArrow

  • ENFIERA 100 INJECTION must be administered by a trained doctor or nurse only. Self-administration of this injection is strictly prohibited due to the potential for serious side effects that require immediate medical attention. Prior to receiving ENFIERA 100 INJECTION, you will be administered pre-medications to help minimize potential adverse reactions. These pre-medications are crucial for ensuring your safety and comfort during the infusion process.
  • The dosage and duration of your treatment with ENFIERA 100 INJECTION will be determined by your doctor, taking into account the severity of your condition, your overall health status, and any other relevant factors. It's essential to adhere to the prescribed treatment plan for optimal results. This medication is administered as an intravenous infusion directly into your vein.
  • During the infusion, you will be closely monitored by healthcare professionals to detect any signs of unwanted side effects. This continuous monitoring allows for prompt intervention and management of any adverse reactions that may occur. If you experience any unusual symptoms or discomfort during or after the infusion, inform your healthcare provider immediately.

FAQs

What are the special precautions I should be aware of before starting treatment with ENFIERA 100 INJECTION?Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are ENFIERA 100 INJECTION-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering ENFIERA 100 INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during ENFIERA 100 INJECTION?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the ENFIERA 100 INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Is weight gain a side effect of ENFIERA 100 INJECTION?Arrow

Weight gain has been reported in patients treated with ENFIERA 100 INJECTION for non-hodgkin’s lymphoma.

Does ENFIERA 100 INJECTION suppress the immune system?Arrow

Yes, can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking ENFIERA 100 INJECTION because it may cause drug-induced immunosuppression.

Is there any interaction of ENFIERA 100 INJECTION with other drugs?Arrow

NULL interaction of ENFIERA 100 INJECTION with other drugs

What precautions should I take while using ENFIERA 100 INJECTION?Arrow

Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently because ENFIERA 100 INJECTION may cause drug-induced immunosuppression. Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease. Vaccination with live virus vaccines is not recommended before or during the treatment for patients with rheumatoid arthritis. Inform your healthcare professional if you have any active infection during the treatment.

Which molecule/combination is used for making ENFIERA 100 INJECTION?Arrow

RITUXIMAB is molecule/combination used for making ENFIERA 100 INJECTION.

For which ailments/diseases/conditions is ENFIERA 100 INJECTION prescribed?Arrow

ENFIERA 100 INJECTION is prescribed for Oncology, Gastroenterology, Rheumatology, Orthopaedics ailments/diseases/conditions.

References

Book Icon

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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Ratings & Review

Excellent service & approach

Raju Palkhade

Reviewed on 18-01-2024

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(5/5)

Service and prize is good

Bhavin Shah

Reviewed on 13-04-2024

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(5/5)

Got medicine which I was searching from yesterday thanks

Donisalya vines

Reviewed on 18-02-2024

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(5/5)

Good service, cheaper medicine and better quality and effective.

Parth Patil

Reviewed on 27-07-2023

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(5/5)

It's good work and always best treatment and every time attend coustomer properly and perfectly

Shraddha Landge

Reviewed on 23-01-2024

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(5/5)


Marketer / Manufacturer Details

ZYDUS LIFESCIENCES LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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