RISTOVA 100MG/10ML INJECTION
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RISTOVA 100MG/10ML INJECTION
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RISTOVA 100MG/10ML INJECTION

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RISTOVA 100MG/10ML INJECTION

By CIPLA PHARMACEUTICAL COMPANY LIMITED

MRP

₹

7133.44

₹6420.09

10 % OFF

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Composition

RITUXIMAB 100 MG

Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About RISTOVA 100MG/10ML INJECTION

  • RISTOVA 100MG/10ML INJECTION contains the active ingredient rituximab. It is used to treat several different conditions in adults and some conditions in children. This injection is used alone or with other medicines to treat certain types of blood cancers: Non-Hodgkin’s Lymphoma (a cancer affecting white blood cells called B-lymphocytes) and Chronic Lymphocytic Leukemia (a common form of cancer affecting B-cells). It is also prescribed for moderate-to-severe Rheumatoid Arthritis (an autoimmune disease where the body's immune system attacks its own joints) when used in combination with methotrexate in adults. Additionally, it treats Granulomatosis with Polyangiitis or Microscopic Polyangiitis (conditions causing inflammation of blood vessels, often affecting the lungs and kidneys) in adults and children aged 2 years and older. It is also indicated for moderate to severe Pemphigus Vulgaris (an autoimmune condition that causes painful blisters on the skin, mouth lining, and other areas).
  • RISTOVA 100MG/10ML INJECTION belongs to a group of medicines called anti-CD20 monoclonal antibodies. This means it targets specific cells in your body that have a marker called CD20, often helping to control the disease. Do not use this injection if you are allergic to rituximab or any other ingredients in it, have a severely weakened immune system, or have a serious active infection. It is important to tell your doctor before starting treatment if you have heart problems, heart failure, or breathing difficulties, as these can be affected by the infusion. You should also inform your doctor if you have ever had a Hepatitis B infection, as this medicine can sometimes cause the infection to become active again, which can be serious. Pregnancy and breastfeeding are not recommended while receiving this injection, and you should use effective contraception.
  • Common side effects you might experience with RISTOVA 100MG/10ML INJECTION include increased risk of infection, lower numbers of red blood cells, feeling dizzy, swelling in the face or body, itchy skin, diarrhea, increased sweating, and changes in blood pressure (low or high). Use reliable birth control methods during the treatment period and for 12 months after your last dose if there is a possibility of becoming pregnant. This medicine can cause severe reactions called infusion reactions during or within 24 hours after it is given. It is crucial to tell your doctor or nurse immediately if you notice any signs of an infusion reaction, such as increased blood pressure, chest pain, headache, trouble breathing, vomiting, skin rashes, throat swelling, or fever. Your healthcare team will monitor you closely during and after the infusion.

Uses of RISTOVA 100MG/10ML INJECTION

  • Helps in the treatment of Non-Hodgkin's lymphoma (NHL).
  • Used in the management of Chronic lymphocytic leukemia (CLL).
  • To reduce symptoms of Rheumatoid Arthritis.
  • For treating Granulomatosis with polyangiitis or microscopic polyangiitis.
  • For skin conditions like Pemphigus vulgaris.

Side Effects of RISTOVA 100MG/10ML INJECTIONArrow

Side effects are unwanted symptoms that can be caused by medicines. While all drugs have the potential to cause side effects, they do not occur in every individual.

  • Swelling in the face and body
  • Diarrhea and nausea
  • Itchy skin
  • Anemia
  • Muscle spasm
  • Headache
  • Urinary tract infection
  • Fever, chills, and shivering
  • Inflammation of nasal cavities
  • Cough, sore throat
  • Loss of hair
  • Increased or decreased blood pressure
  • Chest pain
  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Memory loss, trouble thinking, difficulty in walking

Safety Advice for RISTOVA 100MG/10ML INJECTIONArrow

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Pregnancy

UNSAFE

RISTOVA 100MG/10ML INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of RISTOVA 100MG/10ML INJECTIONArrow

  • This medication, RISTOVA 100MG/10ML INJECTION, must only be given by a healthcare professional trained in administering such treatments, like a doctor or nurse. It is not suitable for self-administration at home. To help minimize potential side effects that might occur during or after the infusion, you will receive other medications, known as pre-medications, before the RISTOVA 100MG/10ML INJECTION is given. The specific amount (dose) of RISTOVA 100MG/10ML INJECTION you receive, and how long you continue the treatment, will be determined by your doctor. This decision is based on factors such as how serious your condition is, your overall health, and how well you respond to the treatment. The medication is administered directly into a vein through a drip (intravenous infusion), which means it enters your bloodstream slowly over a period of time. During and after the infusion, the healthcare team will closely watch you to check for any unexpected or unwanted reactions or side effects. It's important to stay calm and inform the nurse or doctor immediately if you feel unwell or notice anything unusual.

How to store RISTOVA 100MG/10ML INJECTION?Arrow

  • Keep RISTOVA 100MG INJ away from the reach of children and pets.
  • Store RISTOVA 100MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of RISTOVA 100MG/10ML INJECTIONArrow

  • Fights certain blood cancers (like NHL and CLL) by targeting and destroying cancerous B-cells and preventing their growth.
  • Manages autoimmune diseases like Rheumatoid Arthritis by reducing the harmful activity of B-cells, which helps decrease inflammation, pain, swelling, and joint damage.
  • Works by precisely targeting specific immune cells (B-cells with CD20) involved in both cancer and autoimmune responses.

How to use RISTOVA 100MG/10ML INJECTIONArrow

  • RISTOVA 100MG/10ML INJECTION is a powerful medication that requires expert handling. It is crucial that this injection is administered only by a trained healthcare professional, such as a doctor or nurse, in a clinical setting. You must not attempt to self-administer this injection at home. The process is complex and requires careful preparation. Before receiving RISTOVA 100MG/10ML INJECTION, you will typically be given other medicines, known as pre-medication. These are designed to help prevent or reduce potential side effects, such as infusion-related reactions like fever, chills, itching, or breathing difficulties, which can occur during or shortly after the infusion. Your doctor will determine the correct dose and how long your treatment will last. This decision is based on several factors, including the specific condition being treated, its severity, your overall health, body weight, and how you respond to the treatment. RISTOVA 100MG/10ML INJECTION is administered directly into a vein through an intravenous (IV) infusion. This means the medication is slowly dripped into your bloodstream over a period of time. During the infusion and for some time afterward, you will be closely monitored by the healthcare staff. This monitoring is essential to check for any signs of allergic reactions, infusion reactions, changes in your vital signs (like blood pressure or heart rate), or other unexpected side effects. Your safety and well-being are the priority during this treatment. Always follow the instructions given by your healthcare team regarding this medication.

Top Substitutes for RISTOVA 100MG/10ML INJECTION

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LUPIXIMAB 100MG INJLUPIN LIMITED103819.38302320.85
VELTIRO 100MG INJ 10MLZYDUS LIFESCIENCES LIMITED108156.25304562.67
RITUXY 100MG INJ 10MLGLENMARK PHARMACEUTICALS LIMITED108198.44323260.58
MABALL 100MG INJHETERO HEALTHCARE LTD106772.97332450.92
MABTAS 100MG INFUSION 10MLINTAS PHARMACEUTICALS LIMITED107133.8332753.36
ZESTMAB 100MG INJRPG LIFE SCIENCES LIMITED105300.77333337.12
RITUXIPAN 100MG INJ 10MLMANKIND PHARMA LIMITED107983.36343456.99
RIXILTA 100MG INJ 10MLHALSTED PHARMA PVT LTD108842.88350060.42
RITCEMA 100MG INJ 10MLCELON LABORATORIES LTD107500350053.33
CYTOMAB 100MG INJALKEM LABORATORIES LIMITED107520.99353553
XMAB 100MG INJRPG LIFE SCIENCES LIMITED105061.42354729.92
RITUCAD 100MG INJCADILA PHARMACEUTICALS PRIVATE LIMITED107133.8380546.66
RITUXIREL RN 100MG INJ 10MLRELIANCE LIFE SCIENCES107998.55384051.99
RITULASTA 100MG INJ 10MLPLASMAGEN BIOSCIENCES PVT LTD10418539236.26
REDITUX 100MG INJDR REDDY'S LABORATORIES LIMITED107133.72410042.53
TORITZ 100MG INJTORRENT PHARMACEUTICALS LIMITED107937.81414147.83
CONIMAB 100MG INJCONCORD BIOTECH LTD108841.56450049.1
MABTAS N 100MG INJINTAS PHARMACEUTICALS LIMITED107133.8509028.65
ENFIERA 100MG INJZYDUS LIFESCIENCES LIMITED108156.25522036
MABTAS T 100MG INJINTAS PHARMACEUTICALS LIMITED107133.8528925.86
RITUXIREL 100MG INJRELIANCE LIFE SCIENCES108199.13563131.32
EMTUX 100MG INJEMCURE PHARMACEUTICALS LIMITED107128.185702.5420
RITUXEM 100MG INJEMCURE PHARMACEUTICALS LIMITED107133.8571619.87
IKGDAR 100MG INJ 10MLCIPLA PHARMACEUTICAL COMPANY LIMITED107472.815978.2520

FAQs

What are the special precautions I should be aware of before starting treatment with Ristova 100mg injection?Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure. 

What are Ristova 100mg infusion-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering Ristova 100mg injection. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during Ristova 100mg injection?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the Ristova 100mg injection. You will be monitored for heart failure, increased blood pressure, or breathing failure. 

Is weight gain a side effect of Ristova 100mg injection?Arrow

Weight gain has been reported in patients treated with Ristova 100mg  injection for non-hodgkin’s lymphoma. 

Does Ristova 100mg injection suppress the immune system?Arrow

Yes, can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking Ristova 100mg injection because it may cause drug-induced immunosuppression. 

References

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HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021)

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020)

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Marketer / Manufacturer Details

CIPLA PHARMACEUTICAL COMPANY LIMITED

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