X-MAB 100 INJECTION
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X-MAB 100 INJECTION
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X-MAB 100 INJECTION

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X-MAB 100 INJECTION

By RPG LIFE SCIENCES LIMITED

MRP

5061.42

₹3547

29.92 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About X-MAB 100 INJECTION

  • X-MAB 100 INJECTION contains rituximab as its active ingredient. It is prescribed for various conditions in adults, either alone or in conjunction with other medications. These conditions include non-Hodgkin's lymphoma, a cancer affecting B-lymphocytes (a type of white blood cell), and chronic lymphocytic leukemia, another cancer affecting B-cells. Additionally, it is used in combination with methotrexate to treat moderate-to-severe rheumatoid arthritis, an autoimmune disease where the immune system mistakenly attacks the body's own joint cells. X-MAB 100 INJECTION is also indicated for treating granulomatosis with polyangiitis and microscopic polyangiitis, both inflammatory conditions affecting blood vessels, particularly in the lungs and kidneys, for adults and children aged 2 years and older. Furthermore, it is used to manage moderate to severe pemphigus vulgaris, an autoimmune disorder characterized by painful blisters on the skin and mucous membranes.
  • X-MAB 100 INJECTION belongs to a class of drugs known as anti-CD20 monoclonal antibodies. It is crucial to avoid this injection if you have a known allergy to rituximab or any of its other ingredients. It is also contraindicated for individuals with a weakened immune system or any severe active infection. Before starting treatment with X-MAB 100 INJECTION, inform your doctor if you have a history of heart disease, heart failure, or breathing problems. It's also vital to discuss any prior hepatitis B infection with your doctor, as this infection can sometimes reactivate and become severe. The use of X-MAB 100 INJECTION is generally not recommended during pregnancy and breastfeeding.
  • Common side effects associated with X-MAB 100 INJECTION may include blood infections, reduced red blood cell count, dizziness, swelling in the face and body, itchy skin, diarrhea, increased sweating, and fluctuations in blood pressure (either low or high). If you are capable of becoming pregnant, it is essential to use effective contraception during treatment and for 12 months after the last dose. This medicine may cause severe infusion reactions during the infusion or within 24 hours after its completion. Immediately inform your physician or healthcare professional if you experience any infusion reactions such as increased blood pressure, chest pain, headache, breathing difficulties, vomiting, skin rashes, or throat swelling. Regular monitoring is essential to manage any potential side effects effectively.
  • It's important to be aware that X-MAB 100 INJECTION can also potentially interact with other medications you may be taking. Therefore, a complete list of your current medications should be provided to your healthcare provider to avoid any adverse interactions. Furthermore, certain vaccinations might be less effective during treatment with rituximab, so discuss vaccination plans with your doctor. The dosage and frequency of X-MAB 100 INJECTION are determined by your doctor based on your specific condition and response to treatment. Never adjust the dosage yourself. Keep all scheduled appointments with your doctor and laboratory for monitoring your progress.

Uses of X-MAB 100 INJECTION

  • Non-Hodgkin's Lymphoma (NHL) is a type of cancer that begins in the lymphatic system. X-MAB 100 INJECTION can be used in its treatment.
  • Chronic Lymphocytic Leukemia (CLL) is a type of cancer that affects the blood and bone marrow. X-MAB 100 INJECTION may be part of the treatment plan.
  • Rheumatoid Arthritis is a chronic inflammatory disorder affecting many joints, including those in the hands and feet. X-MAB 100 INJECTION might be considered as a treatment option in certain cases.
  • Granulomatosis with Polyangiitis and Microscopic Polyangiitis are rare autoimmune diseases that cause inflammation of blood vessels. X-MAB 100 INJECTION is used in the treatment of these conditions.
  • Pemphigus Vulgaris is a rare autoimmune disorder that causes painful blisters on the skin and mucous membranes. X-MAB 100 INJECTION is sometimes used to manage this condition.

Side Effects of X-MAB 100 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Swelling in the face and body
  • Diarrhea and nausea
  • Itchy skin
  • Anemia
  • Muscle spasm
  • Headache
  • Urinary tract infection
  • Fever, chills, and shivering
  • Inflammation of nasal cavities
  • Cough, sore throat
  • Loss of hair
  • Increased or decreased blood pressure
  • Chest pain
  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Memory loss, trouble thinking, difficulty in walking

Safety Advice for X-MAB 100 INJECTIONArrow

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Pregnancy

UNSAFE

X-MAB 100 INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of X-MAB 100 INJECTIONArrow

  • X-MAB 100 INJECTION should only be administered by a trained doctor or nurse. Self-administration of this injection is strictly prohibited. Prior to receiving X-MAB 100 INJECTION, you will be given pre-medications to minimize potential side effects. Your doctor will determine the appropriate dosage and duration of treatment, taking into account the severity of your condition and other relevant factors. This medication is administered as an intravenous infusion under close medical supervision to monitor for any adverse reactions.
  • During the infusion, the healthcare provider will carefully monitor vital signs and assess for any signs of allergic reactions or other complications. If any concerning symptoms arise, the infusion may be temporarily paused or permanently discontinued. It is essential to inform your doctor about any pre-existing medical conditions, allergies, or medications you are currently taking before starting X-MAB 100 INJECTION treatment. This information will help the doctor to administer it safely and effectively.
  • The dosage and frequency of X-MAB 100 INJECTION will vary depending on the specific condition being treated and your individual response to the medication. It is crucial to adhere to the prescribed treatment schedule and attend all scheduled appointments. Do not hesitate to communicate any concerns or questions you may have with your doctor or nurse throughout the treatment process. They are there to provide support and ensure your well-being.

How to store X-MAB 100 INJECTION?Arrow

  • Keep XMAB 100MG INJ away from the reach of children and pets.
  • Store XMAB 100MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of X-MAB 100 INJECTIONArrow

  • X-MAB 100 INJECTION is a specialized medication classified as a monoclonal antibody. It precisely targets the CD20 antigen, which is prominently displayed on the surface of B-lymphocytes. These B-lymphocytes are a specific kind of white blood cell that plays a crucial role in the body's immune response. This injection is designed to combat Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL).
  • The medicine's mechanism of action involves attaching itself to the B-cells, which triggers a process of cell death in cancerous cells affected by NHL and CLL. By binding to the B-cell, it effectively obstructs cell activation and proliferation, thus exerting potent anticancer effects. In cases of rheumatoid arthritis, X-MAB 100 INJECTION demonstrates its therapeutic properties by impeding rheumatoid factor production.
  • Furthermore, it interferes with antigen presentation, inhibits T-cell activation, and reduces the production of pro-inflammatory cytokines. This multifaceted approach contributes to alleviating the symptoms and progression of rheumatoid arthritis. This targeted approach ensures that the medication acts specifically on the affected cells, minimizing potential harm to healthy cells and maximizing therapeutic benefits.
  • The precise targeting and mechanism of action make it a valuable treatment option for individuals suffering from these conditions. Its role in modulating the immune response and promoting cell death in cancerous B-cells underscores its significance in modern medicine.

How to use X-MAB 100 INJECTIONArrow

  • X-MAB 100 INJECTION is a medication that must be administered strictly by a trained healthcare professional, such as a doctor or nurse. It is crucial that you do not attempt to self-administer this injection. The administration process requires specific medical knowledge and expertise to ensure your safety and the effectiveness of the treatment.
  • Prior to receiving X-MAB 100 INJECTION, your healthcare provider will likely administer pre-medications. These pre-medications are designed to minimize the potential for side effects that can sometimes occur during or after the infusion. It's an important precautionary measure to enhance your comfort and well-being throughout the treatment.
  • The dosage and duration of your X-MAB 100 INJECTION treatment will be determined by your doctor, who will carefully assess factors such as the severity of your condition and your individual response to the medication. The treatment plan is customized to your specific needs to optimize its effectiveness.
  • X-MAB 100 INJECTION will be administered as an intravenous infusion, meaning it will be delivered directly into your bloodstream through a vein. During the infusion process, you will be closely monitored by medical staff to detect any signs of unwanted side effects. This vigilant monitoring ensures that any potential issues are promptly addressed, providing you with the best possible care.

FAQs

What are the special precautions I should be aware of before starting treatment with X-MAB 100 INJECTION?Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are X-MAB 100 INJECTION-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering X-MAB 100 INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during X-MAB 100 INJECTION?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the X-MAB 100 INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Is weight gain a side effect of X-MAB 100 INJECTION?Arrow

Weight gain has been reported in patients treated with X-MAB 100 INJECTION for non-hodgkin’s lymphoma.

Does X-MAB 100 INJECTION suppress the immune system?Arrow

Yes, can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking X-MAB 100 INJECTION because it may cause drug-induced immunosuppression.

Does X-MAB 100 INJECTION interact with other drugs?Arrow

NULL interaction of X-MAB 100 INJECTION with other drungs

What advice should I remember regarding X-MAB 100 INJECTION?Arrow

Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently because X-MAB 100 INJECTION may cause drug-induced immunosuppression. Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease. Vaccination with live virus vaccines is not recommended before or during the treatment for patients with rheumatoid arthritis. Inform your healthcare professional if you have any active infection during the treatment.

Which molecule/combination is used for making X-MAB 100 INJECTION?Arrow

RITUXIMAB is molecule/combination used for making X-MAB 100 INJECTION.

For which ailments/diseases/conditions is X-MAB 100 INJECTION prescribed?Arrow

X-MAB 100 INJECTION is prescribed for ailments related to Oncology, Gastroenterology, Rheumatology, and Orthopaedics.

References

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HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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Marketer / Manufacturer Details

RPG LIFE SCIENCES LIMITED

Country of Origin -

India

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₹3547

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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