ZESTMAB 100MG INJECTION
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ZESTMAB 100MG INJECTION
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ZESTMAB 100MG INJECTION

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ZESTMAB 100MG INJECTION

By RPG LIFE SCIENCES LIMITED

MRP

5300.77

₹3333

37.12 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About ZESTMAB 100MG INJECTION

  • ZESTMAB 100MG INJECTION contains rituximab as its active ingredient. It is prescribed for the management of several conditions in adults, often used independently or in conjunction with other medications. Primary applications include the treatment of non-Hodgkin’s lymphoma, a cancer affecting B-lymphocytes (a type of white blood cell), and chronic lymphocytic leukemia, another common cancer affecting B-cells. This medication is also indicated for moderate-to-severe rheumatoid arthritis, an autoimmune disorder where the immune system mistakenly attacks the body's own joint cells, typically administered alongside methotrexate.
  • Further applications of ZESTMAB 100MG INJECTION include the treatment of granulomatosis with polyangiitis and microscopic polyangiitis, both inflammatory conditions affecting blood vessels, particularly in the lungs and kidneys, and can be used in both adults and children aged 2 years and older. Additionally, it is employed in managing moderate to severe pemphigus vulgaris, an autoimmune condition characterized by painful blisters on the skin and mucous membranes of the mouth, throat, nose, and genitals.
  • ZESTMAB 100MG INJECTION belongs to the therapeutic class of anti-CD20 monoclonal antibodies. It is crucial to avoid this injection if you have a known allergy to rituximab or any of its constituents, have a compromised immune system, or are currently experiencing a severe active infection. Prior to commencing treatment, it is essential to inform your healthcare provider if you have a history of heart disease, heart failure, or breathing difficulties. You should also disclose any prior history of hepatitis B infection, as rituximab treatment can potentially reactivate the virus, leading to severe health consequences. It is generally advised to avoid pregnancy and breastfeeding while undergoing treatment with this injection. Use effective contraceptive measures during the treatment and for 12 months after the last dose if you are of childbearing potential.
  • Common side effects associated with ZESTMAB 100MG INJECTION may include blood infections, reduced red blood cell count (anemia), dizziness, swelling in the face and body (edema), skin itching (pruritus), diarrhea, increased sweating (hyperhidrosis), and fluctuations in blood pressure (hypotension or hypertension). During treatment, and for 12 months following the final dose, it is imperative to use reliable contraception if you are capable of becoming pregnant. This medication carries a risk of severe infusion reactions that may occur during or within 24 hours after administration. Promptly notify your physician or healthcare professional if you experience any signs of an infusion reaction, such as elevated blood pressure, chest pain, headache, breathing difficulties, vomiting, skin rashes, or swelling of the throat.

Uses of ZESTMAB 100MG INJECTION

  • Non-Hodgkin's Lymphoma (NHL): A type of cancer that begins in the lymphatic system, affecting white blood cells called lymphocytes. It's crucial to get ZESTMAB 100MG INJECTION treatment for NHL at the earliest.
  • Chronic Lymphocytic Leukemia (CLL): A slow-growing type of blood and bone marrow cancer that affects lymphocytes. ZESTMAB 100MG INJECTION is used in treatment of this cancer.
  • Rheumatoid Arthritis: A chronic inflammatory disorder affecting many joints, including those in the hands and feet. ZESTMAB 100MG INJECTION will help to ease the pain.
  • Granulomatosis with Polyangiitis or Microscopic Polyangiitis: These are rare autoimmune diseases that cause inflammation of blood vessels. In such cases doctors suggest ZESTMAB 100MG INJECTION.
  • Pemphigus Vulgaris: A rare autoimmune disorder that causes painful blisters on the skin and mucous membranes. Immediate treatment with ZESTMAB 100MG INJECTION is very important.

Side Effects of ZESTMAB 100MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, though not everyone experiences them. Common side effects include:

  • Swelling in the face and body
  • Diarrhea and nausea
  • Itchy skin
  • Anemia
  • Muscle spasm
  • Headache
  • Urinary tract infection
  • Fever, chills, and shivering
  • Inflammation of nasal cavities
  • Cough, sore throat
  • Loss of hair
  • Increased or decreased blood pressure
  • Chest pain
  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Memory loss, trouble thinking, difficulty in walking

Safety Advice for ZESTMAB 100MG INJECTIONArrow

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Pregnancy

UNSAFE

ZESTMAB 100MG INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of ZESTMAB 100MG INJECTIONArrow

  • ZESTMAB 100MG INJECTION should be administered exclusively by a qualified doctor or nurse. Self-administration is strictly prohibited. To mitigate potential side effects, you will receive pre-medications before the ZESTMAB 100MG INJECTION is administered. The dosage and treatment duration will be determined by your doctor, considering the severity of your condition and other relevant factors. The medication will be administered as an intravenous infusion, during which you will be closely monitored for any adverse reactions.
  • Prior to each infusion, your medical team will assess your overall health and vital signs to ensure your suitability for the treatment. They will also discuss any potential risks or concerns you may have. It's crucial to inform your doctor about any existing medical conditions, allergies, or medications you are currently taking.
  • During the infusion process, a healthcare professional will carefully monitor your blood pressure, heart rate, and breathing to detect any early signs of complications. They are trained to manage any reactions that may arise. If you experience any discomfort or unusual symptoms, such as fever, chills, nausea, or skin rash, inform your nurse or doctor immediately.
  • Post-infusion, you will likely be monitored for a short period to ensure there are no delayed reactions. Your doctor will provide you with specific instructions regarding follow-up appointments and any necessary precautions. It is essential to adhere to the prescribed treatment schedule and attend all scheduled appointments to maximize the effectiveness of ZESTMAB 100MG INJECTION.

How to store ZESTMAB 100MG INJECTION?Arrow

  • Keep ZESTMAB 100MG INJ away from the reach of children and pets.
  • Store ZESTMAB 100MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of ZESTMAB 100MG INJECTIONArrow

  • ZESTMAB 100MG INJECTION is a specialized medication classified as a monoclonal antibody. It is designed to specifically target the CD20 antigen, which is found on the surface of B-lymphocytes, a specific type of white blood cell crucial for the body's immune response. By binding to the CD20 antigen, ZESTMAB 100MG INJECTION triggers cell death in cancerous B-cells, making it effective in treating Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL).
  • The mechanism of action involves the drug attaching itself to the B-cell, thereby inhibiting its activation and subsequent growth. This binding action is crucial in eliciting the anticancer effects of the medication. Furthermore, in the context of rheumatoid arthritis, ZESTMAB 100MG INJECTION plays a significant role in reducing the production of rheumatoid factor, limiting antigen presentation, suppressing T-cell activation, and diminishing the production of pro-inflammatory cytokines, all of which contribute to the pathology of rheumatoid arthritis.
  • Essentially, ZESTMAB 100MG INJECTION works through a targeted approach to modulate the immune system. In cancer, it helps eliminate malignant B-cells, while in autoimmune conditions like rheumatoid arthritis, it helps to dampen the overactive immune response that causes inflammation and joint damage. This dual action makes it a versatile therapeutic agent.

How to use ZESTMAB 100MG INJECTIONArrow

  • ZESTMAB 100MG INJECTION should only be administered by a trained doctor or nurse. It is crucial that you do not attempt to self-administer this medication. Prior to receiving ZESTMAB 100MG INJECTION, you will be given other medications, known as pre-medication, to help minimize any potential side effects. These pre-medications are an important part of the treatment protocol and are designed to improve your overall comfort and safety during the infusion process.
  • The dose and duration of your treatment will be determined by your doctor, taking into account the severity of your condition, your overall health, and other relevant factors. This personalized approach ensures that you receive the most appropriate and effective treatment plan tailored to your specific needs. The doctor will carefully assess your response to the medication and adjust the dosage or treatment duration as needed.
  • ZESTMAB 100MG INJECTION will be administered as an intravenous infusion, meaning it will be delivered directly into your vein through a sterile IV line. During the infusion, you will be closely monitored by healthcare professionals to detect any potential unwanted side effects. This close monitoring allows for prompt intervention and management of any adverse reactions, ensuring your safety and well-being throughout the treatment.

FAQs

What are the special precautions I should be aware of before starting treatment with ZESTMAB 100MG INJECTION?Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are ZESTMAB 100MG INJECTION infusion-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering ZESTMAB 100MG INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during ZESTMAB 100MG INJECTION?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the ZESTMAB 100MG INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Is weight gain a side effect of ZESTMAB 100MG INJECTION?Arrow

Weight gain has been reported in patients treated with ZESTMAB 100MG INJECTION for non-hodgkin’s lymphoma.

Does ZESTMAB 100MG INJECTION suppress the immune system?Arrow

Yes, can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking ZESTMAB 100MG INJECTION because it may cause drug-induced immunosuppression.

Are there any known interactions of ZESTMAB 100MG INJECTION with other drugs?Arrow

NULL interaction of ZESTMAB 100MG INJECTION with other drungs

What should I avoid while taking ZESTMAB 100MG INJECTION?Arrow

Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently because ZESTMAB 100MG INJECTION may cause drug-induced immunosuppression. Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease. Vaccination with live virus vaccines is not recommended before or during the treatment for patients with rheumatoid arthritis. Inform your healthcare professional if you have any active infection during the treatment.

Which molecule/combination is used for making ZESTMAB 100MG INJECTION?Arrow

RITUXIMAB is molecule/combination used for making ZESTMAB 100MG INJECTION.

For which ailments/diseases/conditions is ZESTMAB 100MG INJECTION prescribed?Arrow

ZESTMAB 100MG INJECTION is prescribed for ailments/diseases/conditions like Oncology, Gastroenterology, Rheumatology, Orthopaedics.

References

Book Icon

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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Ratings & Review

Quality products and services offered. 🥰

ALIMAMY ABDULAI JALLOH

Reviewed on 08-02-2024

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(5/5)

Good experience with best medicine purchase at affordablee prices.

Aman Rohit M

Reviewed on 05-02-2024

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(5/5)

So good it's give information with medicine

sunil Nayi

Reviewed on 21-04-2024

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(5/5)

Best

Vishva Ukani

Reviewed on 07-01-2024

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(5/5)

Best medicines, Timing and behaviour is very good for human beings

Gyan Rathore

Reviewed on 07-08-2023

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(5/5)


Marketer / Manufacturer Details

RPG LIFE SCIENCES LIMITED

Country of Origin -

India

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ZESTMAB 100MG INJECTION

ZESTMAB 100MG INJECTION

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₹3333

37.12 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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