MABALL 100 INJECTION
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MABALL 100 INJECTION
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MABALL 100 INJECTION

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MABALL 100 INJECTION

By HETERO HEALTHCARE LTD

MRP

7224.5

₹3324

53.99 % OFF

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Product DetailsArrow

About MABALL 100 INJECTION

  • MABALL 100 INJECTION contains rituximab as its active ingredient. It is prescribed for various conditions in adults, either alone or in combination with other medications. These conditions include non-Hodgkin's lymphoma, a cancer affecting B-lymphocytes (a type of white blood cell), and chronic lymphocytic leukemia, a common cancer affecting B-cells. Furthermore, it's used in conjunction with methotrexate to manage moderate-to-severe rheumatoid arthritis, an autoimmune disease where the immune system attacks the joints. Additionally, MABALL 100 INJECTION treats granulomatosis with polyangiitis and microscopic polyangiitis, inflammatory conditions of blood vessels primarily affecting the lungs and kidneys, in both adults and children aged 2 years and older. It also addresses moderate to severe pemphigus vulgaris, an autoimmune disorder causing painful blisters on the skin and mucous membranes.
  • MABALL 100 INJECTION belongs to a class of drugs known as anti-CD20 monoclonal antibodies. Avoid this injection if you are allergic to rituximab or any of its components, have a compromised immune system, or are currently experiencing a severe infection. Before starting treatment, inform your doctor if you have a history of heart disease, heart failure, or breathing difficulties. Disclose any past hepatitis B infection, as it can reactivate in some instances and potentially become severe. It is generally not recommended to use this injection during pregnancy or breastfeeding. Effective contraception is a must during treatment and for 12 months after the last dose for individuals who can become pregnant.
  • Common side effects associated with MABALL 100 INJECTION include blood infections, reduced red blood cell counts, dizziness, facial and bodily swelling, itchy skin, diarrhea, increased sweating, and fluctuations in blood pressure (both low and high). Be vigilant for potential infusion reactions during or within 24 hours of administration. Immediately notify your healthcare provider if you experience any such reactions, including increased blood pressure, chest pain, headache, breathing problems, vomiting, skin rashes, or throat swelling. The use of MABALL 100 INJECTION requires careful monitoring and awareness of potential adverse effects to ensure patient safety.

Uses of MABALL 100 INJECTION

  • Non-Hodgkin's Lymphoma (NHL): This condition refers to a group of cancers that affect the lymphatic system. MABALL 100 INJECTION may be used in the treatment of certain types of NHL to target and destroy cancerous cells.
  • Chronic Lymphocytic Leukemia (CLL): CLL is a type of cancer that affects the blood and bone marrow. MABALL 100 INJECTION can be part of the treatment regimen to help manage and control the progression of CLL.
  • Rheumatoid Arthritis: This is an autoimmune disorder that primarily affects the joints. MABALL 100 INJECTION may be prescribed to reduce inflammation and alleviate symptoms in patients with rheumatoid arthritis when other treatments have not been sufficiently effective.
  • Granulomatosis with Polyangiitis or Microscopic Polyangiitis: These are rare autoimmune diseases that cause inflammation of blood vessels. MABALL 100 INJECTION can be used to suppress the immune system and control the inflammation associated with these conditions.
  • Pemphigus Vulgaris: A rare autoimmune disease that causes blistering of the skin and mucous membranes. MABALL 100 INJECTION can help manage this condition by reducing the body's immune response that leads to blistering.

Side Effects of MABALL 100 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, though not everyone experiences them. Common side effects include swelling in the face and body, diarrhea and nausea, itchy skin, anemia, muscle spasm, headache, urinary tract infection, fever, chills, and shivering, inflammation of nasal cavities, cough, and sore throat.

  • Loss of hair
  • Increased or decreased blood pressure
  • Chest pain
  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Memory loss, trouble thinking, difficulty in walking

Safety Advice for MABALL 100 INJECTIONArrow

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Pregnancy

UNSAFE

MABALL 100 INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of MABALL 100 INJECTIONArrow

  • MABALL 100 INJECTION should only be administered by a qualified healthcare professional, such as a trained doctor or nurse. Self-administration of this injection is strictly prohibited.
  • Prior to receiving MABALL 100 INJECTION, you will be administered pre-medications to help minimize potential side effects. These pre-medications are an important part of the treatment protocol and are designed to improve your comfort and safety during the infusion process.
  • The dosage and duration of your treatment with MABALL 100 INJECTION will be determined by your doctor, taking into account the severity of your condition, your individual response to the medication, and other relevant factors. It is crucial to adhere to your doctor's prescribed dosage and treatment schedule for optimal results.
  • MABALL 100 INJECTION is administered as an intravenous infusion. During the infusion, you will be closely monitored by healthcare professionals for any adverse reactions or unwanted side effects. This careful monitoring ensures that any potential issues are promptly addressed.
  • It's important to inform your doctor about any existing medical conditions, allergies, or medications you are currently taking before starting treatment with MABALL 100 INJECTION. This information will help your doctor make informed decisions about your treatment plan and minimize the risk of complications.

How to store MABALL 100 INJECTION?Arrow

  • Keep MABALL 100MG INJ away from the reach of children and pets.
  • Store MABALL 100MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of MABALL 100 INJECTIONArrow

  • MABALL 100 INJECTION is a targeted therapy that employs a monoclonal antibody to specifically recognize and bind to the CD20 antigen found on the surface of B-lymphocytes. B-lymphocytes are a specific type of white blood cell. By targeting CD20, this medication induces cell death, primarily in the context of Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL), effectively combating these conditions.
  • The binding action of MABALL 100 INJECTION is crucial. It doesn't just attach to the B-cells; it actively blocks their activation and subsequent growth. This inhibitory effect is a key component of its anticancer properties, hindering the proliferation of cancerous B-cells.
  • In the context of rheumatoid arthritis, MABALL 100 INJECTION exhibits a broader range of therapeutic effects. It inhibits the production of rheumatoid factor, a key indicator of the disease. Furthermore, it interferes with antigen presentation, reduces T-cell activation, and suppresses the production of pro-inflammatory cytokines. These actions collectively contribute to reducing inflammation and alleviating the symptoms of rheumatoid arthritis.
  • The precise mechanism of action of MABALL 100 INJECTION allows it to target the disease at its source, providing a powerful tool in the fight against cancer and autoimmune disorders.

How to use MABALL 100 INJECTIONArrow

  • MABALL 100 INJECTION should only be administered by a trained doctor or nurse. It is crucial that you do not attempt to self-administer this injection. Prior to receiving MABALL 100 INJECTION, your healthcare provider will administer pre-medications to help minimize potential side effects. These pre-medications are an important step in ensuring your comfort and safety during the infusion.
  • The dosage and duration of your treatment with MABALL 100 INJECTION will be determined by your doctor. This decision will be based on the severity of your condition, your overall health, and other individual factors. It's essential to adhere to your doctor's prescribed treatment plan for the best possible outcome.
  • MABALL 100 INJECTION is administered as an intravenous infusion. During the infusion process, you will be closely monitored by healthcare professionals for any adverse reactions or unwanted side effects. This vigilant monitoring ensures that any potential issues are promptly addressed. If you experience any unusual symptoms or discomfort during the infusion, inform your healthcare provider immediately.

FAQs

What are the special precautions I should be aware of before starting treatment with MABALL 100 INJECTION?Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are MABALL 100 INJECTION-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering MABALL 100 INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during MABALL 100 INJECTION?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the MABALL 100 INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Is weight gain a side effect of MABALL 100 INJECTION?Arrow

Weight gain has been reported in patients treated with MABALL 100 INJECTION for non-hodgkin’s lymphoma.

Does MABALL 100 INJECTION suppress the immune system?Arrow

Yes, can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking MABALL 100 INJECTION because it may cause drug-induced immunosuppression.

Does MABALL 100 INJECTION interact with other drugs?Arrow

There is no known interaction of MABALL 100 INJECTION with other drugs.

What advice should I follow while taking MABALL 100 INJECTION?Arrow

Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently because MABALL 100 INJECTION may cause drug-induced immunosuppression. Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease. Vaccination with live virus vaccines is not recommended before or during the treatment for patients with rheumatoid arthritis. Inform your healthcare professional if you have any active infection during the treatment.

What molecule/combination is used for making MABALL 100 INJECTION?Arrow

RITUXIMAB is the molecule/combination used for making MABALL 100 INJECTION.

For what ailments/diseases/conditions is MABALL 100 INJECTION prescribed?Arrow

MABALL 100 INJECTION is used to treat ailments related to Oncology, Gastroenterology, Rheumatology, and Orthopaedics.

Can MABALL 100 INJECTION be used to treat cancer?Arrow

Yes, MABALL 100 INJECTION can be used to treat cancer in Oncology.

References

Book Icon

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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Marketer / Manufacturer Details

HETERO HEALTHCARE LTD

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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