RITULASTA 100MG/10ML INJECTION
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RITULASTA 100MG/10ML INJECTION
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RITULASTA 100MG/10ML INJECTION

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RITULASTA 100MG/10ML INJECTION

By PLASMAGEN BIOSCIENCES PVT LTD

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4185

₹4185

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About RITULASTA 100MG/10ML INJECTION

  • RITULASTA 100MG/10ML INJECTION contains the active ingredient rituximab and is prescribed for various conditions in adults. It is used, either alone or in combination with other medications, to treat Non-Hodgkin's Lymphoma (a cancer affecting B-lymphocytes, a type of white blood cell) and Chronic Lymphocytic Leukemia (the most common form of cancer affecting B-cells). It is also used in conjunction with methotrexate to treat moderate-to-severe Rheumatoid Arthritis, an autoimmune disease where the immune system mistakenly attacks the body's own joints. Furthermore, it's indicated for treating Granulomatosis with Polyangiitis or Microscopic Polyangiitis, conditions characterized by blood vessel inflammation primarily affecting the lungs and kidneys in both adults and children aged 2 years and older. Additionally, it is used to manage moderate to severe Pemphigus Vulgaris, an autoimmune disorder that causes painful blisters on the skin and mucous membranes of the mouth, throat, nose, and genitals.
  • RITULASTA 100MG/10ML INJECTION belongs to the class of medications known as anti-CD20 monoclonal antibodies. It should not be administered to individuals with known allergies to rituximab or any of its components, those with weakened immune systems, or those with active, severe infections. Prior to starting treatment, it's essential to inform your healthcare provider if you have a history of heart disease, heart failure, or breathing difficulties. It's also crucial to inform your doctor if you've ever had a Hepatitis B infection, as rituximab can sometimes reactivate the virus, potentially leading to severe complications. This injection is generally not recommended during pregnancy or breastfeeding.
  • Common side effects associated with RITULASTA 100MG/10ML INJECTION may include blood infections, reduced red blood cell counts, dizziness, facial and body swelling, itchy skin, diarrhea, increased sweating, and fluctuations in blood pressure (either low or high). If you are of childbearing potential, it’s important to use effective contraception during treatment and for 12 months after the last dose. This medicine can trigger severe infusion reactions during or within 24 hours of administration. Immediately notify your doctor or another healthcare professional if you experience any signs or symptoms of an infusion reaction, such as elevated blood pressure, chest discomfort, headache, difficulty breathing, vomiting, skin rashes, or throat swelling. Careful monitoring is crucial during and after the infusion to manage any potential adverse events promptly. The dosage and administration schedule will be determined by your physician based on your specific condition and overall health.

Uses of RITULASTA 100MG/10ML INJECTION

  • Non-Hodgkin's Lymphoma (NHL): A type of cancer that begins in the lymphatic system, which is part of the body's immune system. RITULASTA 100MG/10ML INJECTION may be used in the treatment of certain subtypes of NHL.
  • Chronic Lymphocytic Leukemia (CLL): A type of cancer of the blood and bone marrow. RITULASTA 100MG/10ML INJECTION might be considered as a treatment option for individuals affected by CLL.
  • Rheumatoid Arthritis: An autoimmune disorder causing chronic inflammation of the joints. RITULASTA 100MG/10ML INJECTION can be prescribed to help manage symptoms and reduce inflammation associated with rheumatoid arthritis.
  • Granulomatosis with Polyangiitis or Microscopic Polyangiitis: These are rare autoimmune diseases that cause inflammation of blood vessels. RITULASTA 100MG/10ML INJECTION is sometimes used to treat these conditions by suppressing the immune system.
  • Pemphigus Vulgaris: A rare autoimmune disease that causes blistering of the skin and mucous membranes. RITULASTA 100MG/10ML INJECTION may be employed to manage this condition by reducing the production of autoantibodies.

Side Effects of RITULASTA 100MG/10ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. With RITULASTA 100MG/10ML INJECTION, some common and serious side effects may occur.

  • Swelling in the face and body
  • Diarrhea and nausea
  • Itchy skin
  • Anemia
  • Muscle spasm
  • Headache
  • Urinary tract infection
  • Fever, chills, and shivering
  • Inflammation of nasal cavities
  • Cough, sore throat
  • Loss of hair
  • Increased or decreased blood pressure
  • Chest pain
  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Memory loss, trouble thinking, difficulty in walking

Safety Advice for RITULASTA 100MG/10ML INJECTIONArrow

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Pregnancy

UNSAFE

RITULASTA 100MG/10ML INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of RITULASTA 100MG/10ML INJECTIONArrow

  • RITULASTA 100MG/10ML INJECTION should always be administered under the direct supervision of a qualified healthcare professional, such as a trained doctor or nurse. Self-administration is strictly prohibited.
  • Prior to receiving RITULASTA 100MG/10ML INJECTION, you will likely be given pre-medications. These medications are designed to minimize potential side effects associated with the infusion.
  • The dosage and duration of your RITULASTA 100MG/10ML INJECTION treatment will be determined by your doctor. They will carefully consider the severity of your condition, your individual response to the medication, and any other relevant health factors.
  • RITULASTA 100MG/10ML INJECTION is administered intravenously, meaning it is delivered directly into your vein through an infusion. During the infusion process, you will be closely monitored by medical staff for any adverse reactions or unwanted side effects. This ensures your safety and allows for immediate intervention if needed.
  • It's crucial to inform your doctor about any existing medical conditions, allergies, or medications you are currently taking before starting RITULASTA 100MG/10ML INJECTION treatment. This information helps them tailor the treatment plan to your specific needs and minimize the risk of complications.

How to store RITULASTA 100MG/10ML INJECTION?Arrow

  • Keep RITULASTA 100MG INJ 10ML away from the reach of children and pets.
  • Store RITULASTA 100MG INJ 10ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of RITULASTA 100MG/10ML INJECTIONArrow

  • RITULASTA 100MG/10ML INJECTION is a specialized medication containing a monoclonal antibody that specifically targets the CD20 antigen found on the surface of B-lymphocytes, which are a type of white blood cell. In Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL), RITULASTA 100MG/10ML INJECTION works by attaching to these B-cells and triggering cell death, effectively reducing the number of cancerous cells. This targeted approach helps to manage and control these conditions.
  • The binding action of RITULASTA 100MG/10ML INJECTION is crucial as it not only induces cell death but also actively blocks B-cell activation and growth. By preventing these cells from becoming activated and multiplying, the medication exerts its anticancer effects, slowing down the progression of the disease and providing therapeutic benefits. This dual mechanism of action makes it a valuable tool in cancer treatment.
  • In the context of rheumatoid arthritis, RITULASTA 100MG/10ML INJECTION offers therapeutic benefits by inhibiting several key processes involved in the disease's pathology. It reduces the production of rheumatoid factor, a marker of autoimmune activity. Furthermore, it interferes with antigen presentation, T-cell activation, and the production of pro-inflammatory cytokines. By modulating these immune responses, RITULASTA 100MG/10ML INJECTION helps alleviate inflammation and joint damage associated with rheumatoid arthritis.

How to use RITULASTA 100MG/10ML INJECTIONArrow

  • RITULASTA 100MG/10ML INJECTION should only be administered by a trained doctor or nurse in a clinical setting. It is crucial to avoid self-administration of this injection.
  • Prior to receiving RITULASTA 100MG/10ML INJECTION, you will be given other medications, known as pre-medication, to help minimize potential side effects. These pre-medications are an important part of the treatment protocol and are given to ensure your comfort and safety during the infusion.
  • The dose and duration of your treatment with RITULASTA 100MG/10ML INJECTION will be determined by your doctor, taking into account the severity of your condition, your overall health, and other individual factors. It's essential to follow your doctor's specific instructions regarding the treatment schedule.
  • RITULASTA 100MG/10ML INJECTION will be administered as an intravenous infusion, meaning it will be delivered directly into your vein over a period of time. During the infusion, you will be carefully monitored by healthcare professionals for any unexpected or adverse reactions. This close monitoring allows for immediate intervention if any issues arise, ensuring your well-being throughout the procedure.

FAQs

What are the special precautions I should be aware of before starting treatment with RITULASTA 100MG/10ML INJECTION?Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are RITULASTA 100MG/10ML INJECTION infusion-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering RITULASTA 100MG/10ML INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during RITULASTA 100MG/10ML INJECTION?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the RITULASTA 100MG/10ML INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Is weight gain a side effect of RITULASTA 100MG/10ML INJECTION?Arrow

Weight gain has been reported in patients treated with RITULASTA 100MG/10ML INJECTION for non-hodgkin’s lymphoma.

Does RITULASTA 100MG/10ML INJECTION suppress the immune system?Arrow

Yes, can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking RITULASTA 100MG/10ML INJECTION because it may cause drug-induced immunosuppression.

Does RITULASTA 100MG/10ML INJECTION interact with other drugs?Arrow

No known interactions of RITULASTA 100MG/10ML INJECTION with other drugs.

What advice should I follow while taking RITULASTA 100MG/10ML INJECTION?Arrow

Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently because RITULASTA 100MG/10ML INJECTION may cause drug-induced immunosuppression. Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease. Vaccination with live virus vaccines is not recommended before or during the treatment for patients with rheumatoid arthritis. Inform your healthcare professional if you have any active infection during the treatment.

What molecule/combination is used for making RITULASTA 100MG/10ML INJECTION?Arrow

RITUXIMAB is molecule/combination used for making RITULASTA 100MG/10ML INJECTION.

For which ailments/diseases/conditions is RITULASTA 100MG/10ML INJECTION prescribed?Arrow

RITULASTA 100MG/10ML INJECTION is prescribed for ailments/diseases/conditions related to Oncology, Gastroenterology, Rheumatology, and Orthopaedics.

References

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HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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Ratings & Review

Great experience wonderful experience nice palce for low cost medicine

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Reviewed on 10-06-2023

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Good representation and good communication to the cx very helpfull

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Reviewed on 02-02-2024

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(5/5)


Marketer / Manufacturer Details

PLASMAGEN BIOSCIENCES PVT LTD

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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