RITUXEM 100MG/10ML INJECTION
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RITUXEM 100MG/10ML INJECTION
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RITUXEM 100MG/10ML INJECTION

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RITUXEM 100MG/10ML INJECTION

By EMCURE PHARMACEUTICALS LIMITED

MRP

7609.39

₹5716

24.88 % OFF

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Composition

Product DetailsArrow

About RITUXEM 100MG/10ML INJECTION

  • RITUXEM 100MG/10ML INJECTION contains the active ingredient rituximab and is prescribed for various conditions in adults. It is administered alone or in conjunction with other medications to combat non-Hodgkin's lymphoma (a cancer affecting B-lymphocytes) and chronic lymphocytic leukemia (a common cancer affecting B-cells). Additionally, it's used alongside methotrexate to treat moderate-to-severe rheumatoid arthritis, an autoimmune disorder where the immune system mistakenly attacks joint tissues. RITUXEM 100MG/10ML INJECTION also addresses granulomatosis with polyangiitis and microscopic polyangiitis, conditions causing blood vessel inflammation primarily affecting the lungs and kidneys, in both adults and children aged 2 years and older. Furthermore, it's a treatment option for moderate to severe pemphigus vulgaris, another autoimmune condition characterized by painful blisters on the skin and mucous membranes.
  • RITUXEM 100MG/10ML INJECTION is classified as an anti-CD20 monoclonal antibody. Avoid this injection if you have a known allergy to rituximab or any of its components, if you have a weakened immune system, or if you are currently experiencing a severe active infection. Prior to commencing treatment, inform your doctor if you have a history of heart disease, heart failure, or breathing difficulties. It's crucial to discuss any prior hepatitis B infection with your doctor, as rituximab can potentially reactivate the virus, leading to serious complications. The use of RITUXEM 100MG/10ML INJECTION is generally not recommended during pregnancy or breastfeeding.
  • Common side effects associated with RITUXEM 100MG/10ML INJECTION include blood infections, reduced red blood cell counts, dizziness, facial and bodily swelling, itchy skin, diarrhea, increased sweating, and fluctuations in blood pressure (both low and high). If you are capable of becoming pregnant, it is essential to use effective contraception during treatment and for 12 months following the final dose. This medication can trigger severe infusion reactions either during or within 24 hours of administration. Immediately notify your physician or healthcare provider if you experience any infusion-related symptoms, such as elevated blood pressure, chest pain, headache, difficulty breathing, vomiting, skin rashes, or throat swelling. This injection affects the immune system and may increase the risk of infection. Patients should be monitored closely for signs of infection during and after treatment. Regular blood tests will be required to monitor blood cell counts and liver function. It's essential to maintain open communication with your healthcare provider throughout the course of treatment to address any concerns or potential side effects promptly.
  • The mechanism of action of RITUXEM 100MG/10ML INJECTION involves targeting the CD20 protein found on the surface of B-lymphocytes. By binding to this protein, rituximab effectively depletes these cells, which play a key role in various autoimmune diseases and B-cell lymphomas. This targeted depletion helps to reduce the inflammatory response and control the progression of the disease. RITUXEM 100MG/10ML INJECTION is administered intravenously and the dosage and frequency of administration depend on the specific condition being treated and the individual patient's response to therapy.

Uses of RITUXEM 100MG/10ML INJECTION

  • Non-Hodgkin's Lymphoma (NHL): This refers to a group of blood cancers that develop from lymphocytes, a type of white blood cell. It's important to distinguish it from Hodgkin's lymphoma, as the treatment approaches can differ.
  • Chronic Lymphocytic Leukemia (CLL): CLL is a type of cancer in which the bone marrow makes too many lymphocytes. These lymphocytes are abnormal and crowd out healthy blood cells, leading to various complications.
  • Rheumatoid Arthritis: An autoimmune disorder causing chronic inflammation of the joints. This can lead to pain, swelling, stiffness, and loss of function in the affected joints.
  • Granulomatosis with Polyangiitis or Microscopic Polyangiitis: These are rare autoimmune diseases that cause inflammation of blood vessels, leading to organ damage if untreated. Symptoms and severity can vary greatly.
  • Pemphigus Vulgaris: A rare autoimmune disorder that causes painful blisters on the skin and mucous membranes. These blisters can be life-threatening if not properly managed.

Side Effects of RITUXEM 100MG/10ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. RITUXEM 100MG/10ML INJECTION can cause some side effects.

  • Swelling in the face and body
  • Diarrhea and nausea
  • Itchy skin
  • Anemia
  • Muscle spasm
  • Headache
  • Urinary tract infection
  • Fever, chills, and shivering
  • Inflammation of nasal cavities
  • Cough, sore throat
  • Loss of hair
  • Increased or decreased blood pressure
  • Chest pain
  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Memory loss, trouble thinking, difficulty in walking

Safety Advice for RITUXEM 100MG/10ML INJECTIONArrow

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Pregnancy

UNSAFE

RITUXEM 100MG/10ML INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of RITUXEM 100MG/10ML INJECTIONArrow

  • RITUXEM 100MG/10ML INJECTION must be administered exclusively by a qualified healthcare professional, such as a doctor or nurse, who is experienced in managing infusions and potential allergic reactions. Self-administration is strictly prohibited. Prior to receiving RITUXEM 100MG/10ML INJECTION, you will be pre-medicated with other medications, such as antihistamines and corticosteroids, to minimize the risk and severity of potential side effects. These pre-medications help to reduce the likelihood of infusion-related reactions.
  • The dosage and duration of your treatment with RITUXEM 100MG/10ML INJECTION will be determined by your doctor based on several factors, including the specific condition being treated, its severity, your overall health status, and your response to the medication. It is crucial to adhere to your doctor's prescribed dosage and treatment schedule for optimal results.
  • RITUXEM 100MG/10ML INJECTION is administered intravenously as a slow infusion into a vein. During the infusion, you will be closely monitored by healthcare professionals for any signs of adverse reactions or unwanted side effects. The infusion rate will be carefully controlled to minimize the risk of complications. Regular monitoring allows for prompt intervention if any issues arise during the administration process.

How to store RITUXEM 100MG/10ML INJECTION?Arrow

  • Keep RITUXEM 100MG INJ away from the reach of children and pets.
  • Store RITUXEM 100MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of RITUXEM 100MG/10ML INJECTIONArrow

  • RITUXEM 100MG/10ML INJECTION is a targeted therapy that specifically hones in on B-lymphocytes, a type of white blood cell, by attaching to the CD20 antigen on their surface. This mechanism is crucial in treating conditions like Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL), where these B-cells become cancerous. Once RITUXEM 100MG/10ML INJECTION binds to the B-cell, it triggers a process called apoptosis, effectively inducing cell death, which helps to reduce the cancerous B-cell population in NHL and CLL patients.
  • Beyond directly killing cancer cells, RITUXEM 100MG/10ML INJECTION also plays a role in modulating the immune system. By binding to the CD20 antigen, it interferes with the activation and growth signals that cancerous B-cells rely on. This inhibitory action helps to slow down the progression of the disease and prevents the cancerous cells from further multiplying. This dual action of inducing cell death and blocking growth signals contributes to its anticancer effects.
  • In the context of rheumatoid arthritis, RITUXEM 100MG/10ML INJECTION offers therapeutic benefits by targeting B-cells that contribute to the autoimmune response. It inhibits the production of rheumatoid factor, a key marker of the disease, and interferes with antigen presentation, a process that activates T-cells. Additionally, it reduces the production of pro-inflammatory cytokines, further dampening the inflammatory cascade in rheumatoid arthritis, ultimately leading to reduced joint inflammation and pain.

How to use RITUXEM 100MG/10ML INJECTIONArrow

  • RITUXEM 100MG/10ML INJECTION should only be administered by a trained doctor or nurse in a clinical setting. It is crucial that you do not attempt to self-administer this medication. Prior to receiving RITUXEM 100MG/10ML INJECTION, you will be given pre-medications to help minimize potential side effects. These pre-medications are typically administered to prevent or lessen infusion-related reactions.
  • The dosage and duration of your treatment with RITUXEM 100MG/10ML INJECTION will be determined by your doctor. This decision will be based on several factors, including the severity of your condition, your overall health, and your response to the medication. It is important to follow your doctor's instructions carefully regarding the treatment schedule.
  • RITUXEM 100MG/10ML INJECTION is administered as an intravenous infusion, which means it is delivered directly into your vein through a needle. During the infusion, you will be closely monitored by healthcare professionals to detect any signs of adverse reactions or unwanted side effects. If you experience any unusual symptoms during or after the infusion, inform your doctor or nurse immediately.

FAQs

What are the special precautions I should be aware of before starting treatment with RITUXEM 100MG/10ML INJECTION?Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are RITUXEM 100MG/10ML INJECTION-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering RITUXEM 100MG/10ML INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during RITUXEM 100MG/10ML INJECTION?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the RITUXEM 100MG/10ML INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Is weight gain a side effect of RITUXEM 100MG/10ML INJECTION?Arrow

Weight gain has been reported in patients treated with RITUXEM 100MG/10ML INJECTION for non-hodgkin’s lymphoma.

Does RITUXEM 100MG/10ML INJECTION suppress the immune system?Arrow

Yes, can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking RITUXEM 100MG/10ML INJECTION because it may cause drug-induced immunosuppression.

NULL interaction of RITUXEM 100MG/10ML INJECTION with other drungsArrow

NULL interaction of RITUXEM 100MG/10ML INJECTION with other drungs

What advice should i follow while taking RITUXEM 100MG/10ML INJECTION?Arrow

Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently because RITUXEM 100MG/10ML INJECTION may cause drug-induced immunosuppression. Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease. Vaccination with live virus vaccines is not recommended before or during the treatment for patients with rheumatoid arthritis. Inform your healthcare professional if you have any active infection during the treatment.

Which molecule/combination is used for making RITUXEM 100MG/10ML INJECTION?Arrow

RITUXIMAB is molecule/combination used for making RITUXEM 100MG/10ML INJECTION.

For which ailments/diseases/conditions RITUXEM 100MG/10ML INJECTION is prescribed?Arrow

RITUXEM 100MG/10ML INJECTION is prescribed for ailments/diseases/conditions like Oncology, Gastroenterology, Rheumatology, Orthopaedics.

References

Book Icon

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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Ratings & Review

Nice experience, always!

Ashutosh Buch

Reviewed on 24-02-2023

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(5/5)

Find the medicine which was quite hard to find in the vicinity

devnarayan yadav

Reviewed on 06-12-2022

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(4/5)

Excellent service and support 24/7 Supportive and co operative staff.

Ajay Nayak Dhadkan

Reviewed on 13-01-2024

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(5/5)

Best service always... Best staff ..thank u being over life part

Nisha Khan

Reviewed on 01-07-2023

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(5/5)

Genuine product....

Saurav

Reviewed on 11-01-2024

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(5/5)


Marketer / Manufacturer Details

EMCURE PHARMACEUTICALS LIMITED

Country of Origin -

India

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RITUXEM 100MG/10ML INJECTION

RITUXEM 100MG/10ML INJECTION

MRP

7609.39

₹5716

24.88 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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