AZACAMEN 100 INJECTION
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AZACAMEN 100 INJECTION
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AZACAMEN 100 INJECTION

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AZACAMEN 100 INJECTION

By MEDICAMEN BIOTECH LTD

MRP

2200

₹2200

10

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Product DetailsArrow

About AZACAMEN 100 INJECTION

  • AZACAMEN 100 INJECTION is a medication prescribed for adult patients diagnosed with Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) who are not suitable candidates for stem cell transplantation. It is crucial to understand these conditions to appreciate the role of this injection.
  • Myelodysplastic Syndromes (MDS) are a group of diverse bone marrow disorders characterized by the ineffective production of blood cells. In MDS, the bone marrow fails to produce sufficient numbers of healthy and functional blood cells, leading to various complications such as anemia (low red blood cell count), thrombocytopenia (low platelet count), and neutropenia (low neutrophil count). This can result in fatigue, increased susceptibility to infections, and bleeding problems.
  • Acute Myeloid Leukemia (AML) is a type of cancer that affects the bone marrow and blood. It is characterized by the rapid proliferation of abnormal, immature white blood cells called blasts. These blasts crowd the bone marrow, interfering with the production of normal blood cells. As a result, individuals with AML may experience symptoms such as fatigue, fever, frequent infections, easy bleeding or bruising, and bone pain. AZACAMEN 100 INJECTION helps to manage these conditions by working on the underlying mechanisms that cause the production of unhealthy blood cells.
  • AZACAMEN 100 INJECTION's mechanism of action involves influencing the way DNA functions within cells, ultimately helping to restore normal blood cell production and manage the progression of MDS and AML in patients for whom stem cell transplant is not a viable option.

Uses of AZACAMEN 100 INJECTION

  • Treatment of Acute Myeloid Leukemia with 20-30% blasts in patients who are not eligible for Hematopoietic stem cell transplant. This involves managing the condition with AZACAMEN 100 INJECTION, focusing on patients unsuitable for more intensive treatments like stem cell transplants, and aims to control the leukemia's progression and improve patient outcomes through alternative therapeutic strategies.
  • Intermediate-2 and High-risk Myelodysplastic syndrome (MDS). This addresses the management of Myelodysplastic Syndromes that fall into the intermediate-2 and high-risk categories, typically involving treatment with AZACAMEN 100 INJECTION to help manage the disease's progression, reduce the risk of transforming into acute leukemia, and improve overall blood cell production and function.

Side Effects of AZACAMEN 100 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines; however, not everyone experiences them. With AZACAMEN 100 INJECTION, be aware of both serious and common side effects.

  • Unexpected bleeding, with blood in stool and urine
  • Fever
  • Pneumonia, characterized by chest pain or breathlessness.
  • Allergic reaction with symptoms of swelling of lips, itching or rashes.
  • Seizures, loss of consciousness, severe headache or bleeding in the brain
  • Frequent urination with pain or burning sensation
  • Disturbances in the blood count (RBC, WBC, Platelets)
  • Nausea, vomiting, diarrhea
  • Constipation
  • Tiredness
  • Skin reaction like redness and pain at the site of injection
  • Decreased appetite
  • Dizziness
  • Pain in extremities
  • Joint pain
  • Stomach pain
  • Headache
  • Sore nose and throat
  • Rashes and bruising

Safety Advice for AZACAMEN 100 INJECTIONArrow

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Pregnancy

UNSAFE

AZACAMEN 100 INJECTION could be harmful to the unborn fetus. Inform your physician if you are pregnant or planning to get pregnant

Dosage of AZACAMEN 100 INJECTIONArrow

  • AZACAMEN 100 INJECTION should only be administered under the direct supervision of a qualified healthcare professional. This ensures that the injection is given correctly and that any potential side effects can be promptly managed. The dosage will be determined by your physician, who will take into account several factors, including your height, weight, overall health condition, and the specific medical reason for using this medication.
  • The injection is typically administered subcutaneously, which means it is injected under the skin. Common injection sites include the thigh, stomach, or upper arm. Your healthcare provider will rotate injection sites to minimize skin irritation and ensure proper absorption of the medication. It is crucial to follow your doctor's instructions precisely regarding the frequency and timing of injections to achieve the best possible therapeutic outcome.
  • Self-administration of AZACAMEN 100 INJECTION is generally not recommended unless you have received comprehensive training from a healthcare professional. This training will cover proper injection techniques, hygiene protocols, and how to manage any potential complications. If you experience any unusual symptoms or have concerns about your treatment, consult your doctor immediately.

How to store AZACAMEN 100 INJECTION?Arrow

  • Keep AZACAMEN 100MG INJ away from the reach of children and pets.
  • Store AZACAMEN 100MG INJ at room temperature.

Benefits of AZACAMEN 100 INJECTIONArrow

  • In Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML), the emergence of cancerous cells stems from transcriptional repression, a process where gene expression is silenced due to hypermethylation of DNA. Think of it as specific genes being 'turned off' because of chemical modifications to the DNA structure. This silencing involves proteins binding to DNA, directly or indirectly, hindering the gene's ability to be copied and utilized by the cell.
  • AZACAMEN 100 INJECTION works by converting into its active form once inside the body. This active form then integrates itself into the RNA and DNA of rapidly dividing cells, including cancer cells. By inserting itself into these crucial molecules, AZACAMEN 100 INJECTION disrupts their normal function, specifically interfering with cell division and growth. This interference ultimately leads to a toxic effect on the cancer cells, preventing them from further multiplying and spreading.
  • The medication's mechanism specifically targets the rapid proliferation of cancer cells, making it effective against MDS and AML. This targeted approach helps to control the abnormal growth of these cells and manage the symptoms associated with these conditions. This targeted action helps arrest the spread of disease and also helps alleviate any associated symptoms.

How to use AZACAMEN 100 INJECTIONArrow

  • Administer AZACAMEN 100 INJECTION strictly under the guidance and supervision of a qualified physician. Self-administration is strongly discouraged to ensure your safety and the effectiveness of the treatment.
  • The dosage of AZACAMEN 100 INJECTION will be determined by your physician, who will carefully consider several factors including your height, weight, overall health condition, and the specific nature of your medical needs. Adhering to the prescribed dosage is crucial for optimal results.
  • AZACAMEN 100 INJECTION is administered via subcutaneous injection, meaning it is injected under the skin. The preferred injection sites include the thigh, stomach, or upper arm. Your physician or a trained healthcare professional will guide you on the proper injection technique and site selection.
  • It is essential to follow your doctor's instructions precisely regarding the frequency and timing of injections. Do not alter the dosage or administration schedule without consulting your physician. Regular monitoring by your healthcare provider is also necessary to assess your response to the medication and make any necessary adjustments to your treatment plan.

FAQs

How to use AZACAMEN 100 INJECTION?Arrow

Take only under the supervision of the physician. Doctor’s will decide the dose based on patients height, weight and general condition. AZACAMEN 100 INJECTION is administered under the skin of your thigh, stomach or upper arm.

Does AZACAMEN 100 INJECTION cause hair loss?Arrow

No, AZACAMEN 100 INJECTION does not cause hair loss even after using it for a prolonged period of time.

How does AZACAMEN 100 INJECTION work?Arrow

AZACAMEN 100 INJECTION binds to RNA and DNA, interrupts their activity in actively multiplying cells and exhibits a toxic effect on cancer cells.

Is AZACAMEN 100 INJECTION chemotherapy?Arrow

Yes. AZACAMEN 100 INJECTION is chemotherapy and it is used in the treatment of cancers. It interferes with the cell's DNA synthesis and decreases the growth and multiplication (cytotoxic effect).

What are the side effects of AZACAMEN 100 INJECTION?Arrow

The common side effects of AZACAMEN 100 INJECTION are nausea, vomiting, diarrhea, constipation, tiredness, decreased appetite, rashes, redness of skin, dizziness, joint pain, headache, sore throat and nose.

Is it safe to drive after taking an AZACAMEN 100 INJECTION?Arrow

It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machineries after taking this medication.

What is the interaction of AZACAMEN 100 INJECTION with other drugs?Arrow

There is no known interaction of AZACAMEN 100 INJECTION with other drugs.

What precautions should I take while taking AZACAMEN 100 INJECTION?Arrow

Inform the doctor if the patient has any allergy reactions, respiratory problems,kidney, liver, heart problems and medication taken for different medical conditions before taking this injection as they worsen the condition. Avoid using this injection if the patient is planning for pregnancy or during pregnancy and in breast feeding mothers as this medicine causes harmful effects in the developing baby. Take this injection only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight and general condition. It is administered under the skin of your thigh, stomach or upper arm.

What molecule/combination is used for making AZACAMEN 100 INJECTION?Arrow

AZACITIDINE is the molecule/combination used for making AZACAMEN 100 INJECTION.

For what conditions is AZACAMEN 100 INJECTION prescribed?Arrow

AZACAMEN 100 INJECTION is prescribed for ailments/diseases/conditions related to Oncology.

References

Book Icon

K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, 60(4):721-741

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Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of Azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018

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Dr.Reddy’s Laboratories

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Nice service All required drugs are available 😊

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Discount on medicine is good But OTC discount is zero and very low

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Reviewed on 05-12-2022

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Marketer / Manufacturer Details

MEDICAMEN BIOTECH LTD

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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