AZACITIDINE 100MG INJECTION
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AZACITIDINE 100MG INJECTION
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AZACITIDINE 100MG INJECTION

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AZACITIDINE 100MG INJECTION

By DR REDDY'S LABORATORIES LIMITED

MRP

5079

₹4317.15

15 % OFF

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Product Details
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About AZACITIDINE 100MG INJECTION

  • AZACITIDINE 100MG INJECTION is a medicine given as an injection. It is used to help treat certain blood and bone marrow disorders in adults. Specifically, it helps patients who have Myelodysplastic Syndromes (often called MDS) or a type of blood cancer called Acute Myeloid Leukemia (AML). This treatment is typically chosen for adults who are not able to have a stem cell transplant, which is another common treatment for these conditions. MDS is a condition where the bone marrow doesn't work properly and fails to make enough healthy blood cells. This can lead to problems like anemia (low red blood cells), infections (low white blood cells), and easy bleeding (low platelets).
  • AML is a more serious condition, a type of cancer that starts in the bone marrow. In AML, the bone marrow produces many abnormal, immature blood cells (blasts) that don't work correctly and can crowd out the healthy cells. AZACITIDINE 100MG INJECTION works by affecting the genetic material (DNA and RNA) in the bone marrow cells, aiming to help them mature properly and function better. It may help improve blood counts and potentially slow down the progression of these diseases. Your doctor will decide if AZACITIDINE 100MG INJECTION is the right treatment for you based on your specific condition and overall health.

Uses of AZACITIDINE 100MG INJECTION

  • Used for treating Acute Myeloid Leukemia in patients whose condition involves 20-30% blasts and who are not suitable candidates for a Haemopoietic stem cell transplant.
  • Used in the management of Myelodysplastic syndrome (MDS) falling into the Intermediate-2 and High-risk categories.

Side Effects of AZACITIDINE 100MG INJECTION
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Side effects are unwanted symptoms caused by medicines. Not everyone experiences them, even though all medicines can cause side effects.

Safety Advice for AZACITIDINE 100MG INJECTION
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Pregnancy

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AZACITIDINE 100MG INJECTION could be harmful to the unborn fetus. Inform your physician if you are pregnant or planning to get pregnant. 

Dosage of AZACITIDINE 100MG INJECTION
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  • You should only take AZACITIDINE 100MG INJECTION exactly as prescribed by your doctor. This medication is a powerful treatment and requires expert medical guidance. Your doctor is the only one who can determine the correct amount of AZACITIDINE 100MG INJECTION you need. The dose is carefully calculated based on several factors, including your body size (like height and weight) and your overall health condition. This personalized approach ensures you receive the most effective treatment for your specific needs.
  • The injection itself is given just under the skin, which is called a subcutaneous injection. Common places for this injection are your thigh, your stomach area (abdomen), or your upper arm. It is crucial to follow your doctor's instructions regarding where and how often to receive this injection. Never attempt to adjust the dose or injection site without consulting your physician first.

How to store AZACITIDINE 100MG INJECTION?
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  • Keep AZACITIDINE 100MG INJ away from the reach of children and pets.
  • Store AZACITIDINE 100MG INJ at room temperature.

Benefits of AZACITIDINE 100MG INJECTION
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  • In conditions like Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML), the abnormal growth of tumor cells is often linked to essential genes being improperly silenced. This gene silencing, known as transcriptional repression, occurs largely because of DNA hypermethylation, where too many chemical tags are added to the DNA, preventing the cell from reading the genetic code correctly. This blocks the production of proteins needed for normal cell function, growth control, and maturation. AZACITIDINE 100MG INJECTION is designed to counteract this. Once inside the body, its active form is incorporated into the DNA and RNA of rapidly dividing cells, such as cancer cells. By inserting itself into the DNA, AZACITIDINE 100MG INJECTION interferes with the enzymes responsible for adding these extra methyl tags. This interference helps to reverse the abnormal hypermethylation patterns, allowing the previously silenced genes to become active again. Reactivating these genes helps restore the cell's ability to control its own growth and encourages immature blood cells to mature into healthy, functional cells. This disruption of the abnormal methylation and gene silencing process directly targets the proliferation of cancer cells, exerting a toxic effect on them while potentially improving the production of normal blood cells, thereby addressing the underlying causes of MDS and AML at a molecular level.

How to use AZACITIDINE 100MG INJECTION
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  • AZACITIDINE 100MG INJECTION must always be given to you by a healthcare professional or directly under the careful supervision of your doctor. This is a powerful medicine that requires expert handling and monitoring. Your doctor is the best person to decide the correct amount (dose) of AZACITIDINE 100MG INJECTION for you. This decision is made after considering several important factors, including your body size (height and weight), your overall health status, and how you are responding to treatment.
  • The injection is typically given under the skin (subcutaneously). The common areas for this injection are your thigh, stomach (abdomen), or the upper part of your arm. These sites are often rotated to avoid discomfort and skin issues. It's crucial never to attempt to administer this injection yourself unless specifically instructed and trained by your healthcare provider. Always follow your doctor's instructions precisely regarding your treatment schedule and any preparation needed. If you have any questions or concerns about how or when you will receive your AZACITIDINE 100MG INJECTION, please talk to your doctor or nurse. They are there to help you understand your treatment.

FAQs

How to use AZACITIDINE 100MG INJECTION?

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Take AZACITIDINE 100MG INJECTION only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. AZACITIDINE 100MG INJECTION is administered under the skin of your thigh, stomach, or upper arm.

Does AZACITIDINE 100MG INJECTION cause hair loss?

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No, AZACITIDINE 100MG INJECTION does not cause hair loss even after using it for a prolonged period of time.

How does AZACITIDINE 100MG INJECTION work?

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AZACITIDINE 100MG INJECTION binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells.

Is AZACITIDINE 100MG INJECTION chemotherapy?

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Yes. AZACITIDINE 100MG INJECTION is chemotherapy used in the treatment of cancers. It interferes with the cell's DNA synthesis and decreases growth and multiplication (cytotoxic effect).

What are the side effects of AZACITIDINE 100MG INJECTION?

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The common side effects of AZACITIDINE 100MG INJECTION are Nausea, vomiting, diarrhea, constipation, tiredness, decreased appetite, rashes, redness of the skin, dizziness, joint pain, headache, sore throat, and nose.

Is it safe to drive after taking AZACITIDINE 100MG INJECTION?

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It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking this medication.

What precautions should I take before using AZACITIDINE 100MG INJECTION?

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Inform the doctor if you have any allergy reactions, respiratory problems, kidney, liver, or heart problems, and medication taken for different medical conditions before taking this injection as they may worsen your condition. Avoid using this injection if you are planning for pregnancy or during pregnancy and in breastfeeding mothers as this medicine causes harmful effects in the developing baby.

How should AZACITIDINE 100MG INJECTION be administered?

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Take AZACITIDINE 100MG INJECTION only under the supervision of the physician. Doctors will decide the dose based on your height, weight, and general condition. It is administered under the skin of your thigh, stomach or upper arm.

What is the main molecule in AZACITIDINE 100MG INJECTION?

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AZACITIDINE is the main molecule used to make AZACITIDINE 100MG INJECTION.

What conditions does AZACITIDINE 100MG INJECTION treat?

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AZACITIDINE 100MG INJECTION is prescribed for Anti Cancer conditions.

Is AZACITIDINE 100MG INJECTION used for cancer treatment?

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Yes, AZACITIDINE 100MG INJECTION is used in the treatment of Anti Cancer conditions.

References

Book Icon

K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, [May 2003], 60(4):721-741

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Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018

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Dr.Reddy’s Laboratories

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DR REDDY'S LABORATORIES LIMITED

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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