AZISHIL 100MG INJECTION
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AZISHIL 100MG INJECTION
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AZISHIL 100MG INJECTION

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AZISHIL 100MG INJECTION

By SHILPA MEDICARE LTD

MRP

1999

₹1999

10

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Product DetailsArrow

About AZISHIL 100MG INJECTION

  • AZISHIL 100MG INJECTION is prescribed for adults diagnosed with Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML), particularly when they are not suitable candidates for stem cell transplantation. Myelodysplastic Syndrome is a condition where the bone marrow malfunctions, leading to the insufficient production of healthy blood cells.
  • Acute Myeloid Leukemia, on the other hand, is a form of bone marrow cancer characterized by the release of immature blood cells into the bloodstream. AZISHIL 100MG INJECTION aims to target and manage these conditions, improving blood cell production and overall health.
  • Before commencing treatment with AZISHIL 100MG INJECTION, it's crucial to inform your doctor about any allergies you may have to the drug's components. Disclose your complete medical history, including any pre-existing conditions and current medications you are taking. This information is vital for your doctor to assess the safety and suitability of the treatment.
  • Furthermore, if you are pregnant, breastfeeding, or planning to conceive, discuss this with your physician. AZISHIL 100MG INJECTION may have potential effects on the fetus or infant, and your doctor can help you weigh the risks and benefits before starting the medication. They may recommend alternative treatment options or adjust the dosage as necessary to ensure your well-being and the health of your baby.

Uses of AZISHIL 100MG INJECTION

  • Treatment of Acute Myeloid Leukemia with 20-30% blasts in patients who are not eligible for Hematopoietic stem cell transplant. This medication offers a therapeutic approach for individuals with Acute Myeloid Leukemia who, due to various health factors, cannot undergo a Hematopoietic stem cell transplant. It aims to manage the disease progression and improve the patient's quality of life.
  • Intermediate-2 and High-risk Myelodysplastic syndrome (MDS). This refers to a category of Myelodysplastic Syndromes that are classified as having a higher risk of transforming into acute leukemia. The medication is used in these cases to manage the symptoms and potentially delay or prevent the progression to a more aggressive form of the disease.

Side Effects of AZISHIL 100MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Unexpected bleeding, with blood in stool and urine
  • Fever
  • Pneumonia, characterized by chest pain or breathlessness.
  • Allergic reaction with symptoms of swelling of lips, itching or rashes.
  • Seizures, loss of consciousness, severe headache or bleeding in the brain
  • Frequent urination with pain or burning sensation
  • Disturbances in the blood count (RBC, WBC, Platelets)
  • Nausea, vomiting, diarrhea
  • Constipation
  • Tiredness
  • Skin reaction like redness and pain at the site of injection
  • Decreased appetite
  • Dizziness
  • Pain in extremities
  • Joint pain
  • Stomach pain
  • Headache
  • Sore nose and throat
  • Rashes and bruising

Safety Advice for AZISHIL 100MG INJECTIONArrow

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Pregnancy

UNSAFE

AZISHIL 100MG INJECTION could be harmful to the unborn fetus. Inform your physician if you are pregnant or planning to get pregnant.

Dosage of AZISHIL 100MG INJECTIONArrow

  • Administer AZISHIL 100MG INJECTION strictly under the guidance and supervision of a qualified physician. Self-administration is strongly discouraged to ensure your safety and the effectiveness of the treatment.
  • The precise dosage of AZISHIL 100MG INJECTION will be determined by your physician, taking into account several factors, including your height, weight, overall health status, and the specific condition being treated. This personalized approach ensures that you receive the optimal dose for your individual needs.
  • AZISHIL 100MG INJECTION is administered subcutaneously, meaning it is injected under the skin. Your physician or a trained healthcare professional will administer the injection into areas such as the thigh, stomach, or upper arm, rotating injection sites to minimize discomfort and potential skin irritation. Follow their instructions carefully for best results.
  • It is crucial to adhere to the prescribed dosage and administration schedule provided by your physician. Do not attempt to adjust the dosage or frequency of injections without consulting your healthcare provider. Consistent and proper administration is key to achieving the desired therapeutic outcome.

How to store AZISHIL 100MG INJECTION?Arrow

  • Keep AZISHIL 100MG INJ away from the reach of children and pets.
  • Store AZISHIL 100MG INJ at room temperature.

Benefits of AZISHIL 100MG INJECTIONArrow

  • In Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML), the emergence of tumor cells stems from transcriptional repression, a process where gene expression is silenced due to DNA hypermethylation. This hypermethylation essentially acts like a switch, turning off critical genes that would normally regulate cell growth and differentiation. Transcriptional repression involves proteins binding to DNA, either directly or indirectly, to inhibit the transcription of specific genes or gene sets. Think of it as a roadblock preventing the cell from reading and using the instructions encoded in those genes. AZISHIL 100MG INJECTION, in its active form, targets both RNA and DNA within rapidly dividing cells.
  • By binding to these nucleic acids, AZISHIL 100MG INJECTION disrupts their normal function. It interferes with the cell's ability to replicate its DNA, transcribe RNA, and ultimately produce the proteins necessary for cell survival and proliferation. This interference leads to a toxic effect specifically on cancer cells, which are characterized by their uncontrolled and rapid division. The drug essentially sabotages the cellular machinery responsible for cancer's aggressive growth. AZISHIL 100MG INJECTION preferentially affects these fast-growing cells, offering a targeted approach to cancer treatment while minimizing damage to healthy, slower-growing tissues. This targeted action is crucial for reducing side effects and improving patient outcomes.
  • The mechanism of AZISHIL 100MG INJECTION provides a crucial advantage in treating MDS and AML. By targeting the fundamental processes of DNA and RNA activity, the drug effectively hinders the proliferation of cancerous cells. This approach offers a pathway to manage and potentially eradicate the disease, leading to improved patient prognosis.

How to use AZISHIL 100MG INJECTIONArrow

  • Administer AZISHIL 100MG INJECTION strictly under the guidance and supervision of a qualified physician or healthcare professional. Self-administration is strongly discouraged due to the potential for complications and the need for accurate dosage adjustments.
  • The dosage of AZISHIL 100MG INJECTION will be determined by your physician based on a comprehensive evaluation of your individual health profile. Factors considered include your height, weight, overall health condition, and the specific medical condition being treated. Adhering to the prescribed dosage is crucial for achieving optimal therapeutic outcomes and minimizing the risk of adverse effects.
  • AZISHIL 100MG INJECTION is administered subcutaneously, meaning it is injected beneath the skin. The injection site typically includes the thigh, stomach (abdomen), or upper arm. Your healthcare provider will instruct you on the proper injection technique and the rotation of injection sites to prevent skin irritation and ensure consistent absorption of the medication.
  • Before each injection, carefully inspect the AZISHIL 100MG INJECTION solution for any particulate matter or discoloration. Do not use the solution if it appears cloudy, discolored, or contains visible particles. Use a new, sterile syringe and needle for each injection to prevent contamination.
  • If you experience any pain, swelling, redness, or other adverse reactions at the injection site, notify your physician immediately. They can assess the situation and provide appropriate medical advice.
  • It is important to maintain open communication with your physician throughout the course of treatment with AZISHIL 100MG INJECTION. Report any changes in your health status, any new medications you are taking, or any concerns you may have. Regular follow-up appointments are essential for monitoring your progress and ensuring the safe and effective use of this medication.

FAQs

How to use AZISHIL 100MG INJECTION?Arrow

Take only under the supervision of the physician. Doctor’s will decide the dose based on patients height, weight and general condition. AZISHIL 100MG INJECTION is administered under the skin of your thigh, stomach or upper arm.

Does AZISHIL 100MG INJECTION cause hair loss?Arrow

No, AZISHIL 100MG INJECTION does not cause hair loss even after using it for a prolonged period of time.

How does AZISHIL 100MG INJECTION work?Arrow

AZISHIL 100MG INJECTION binds to RNA and DNA, interrupts their activity in actively multiplying cells and exhibits a toxic effect on cancer cells.

Is AZISHIL 100MG INJECTION chemotherapy?Arrow

Yes. AZISHIL 100MG INJECTION is chemotherapy and it is used in the treatment of cancers. It interferes with the cell's DNA synthesis and decreases the growth and multiplication (cytotoxic effect).

What are the side effects of AZISHIL 100MG INJECTION?Arrow

The common side effects of AZISHIL 100MG INJECTION are nausea, vomiting, diarrhea, constipation, tiredness, decreased appetite, rashes, redness of skin, dizziness, joint pain, headache, sore throat and nose.

Is it safe to drive after taking an AZISHIL 100MG INJECTION?Arrow

It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machineries after taking this medication.

What are the interactions of AZISHIL 100MG INJECTION with other drugs?Arrow

There is no known interaction information available regarding AZISHIL 100MG INJECTION with other drugs.

What precautions should I take while taking AZISHIL 100MG INJECTION?Arrow

Inform the doctor if the patient has any allergy reactions, respiratory problems,kidney, liver, heart problems and medication taken for different medical conditions before taking this injection as they worsen the condition. Avoid using this injection if the patient is planning for pregnancy or during pregnancy and in breast feeding mothers as this medicine causes harmful effects in the developing baby. Take this injection only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight and general condition. It is administered under the skin of your thigh, stomach or upper arm.

What is AZISHIL 100MG INJECTION made of?Arrow

AZISHIL 100MG INJECTION is made of AZACITIDINE molecule/combination.

What type of cancers is AZISHIL 100MG INJECTION used to treat?Arrow

AZISHIL 100MG INJECTION is used to treat ailments/diseases/conditions related to Oncology.

References

Book Icon

K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, [May 2003], 60(4):721-741

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Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of Azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018

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Dr.Reddy’s Laboratories

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Ratings & Review

Proper medicine at big saving rate

Mukesh Jain

Reviewed on 24-01-2024

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(5/5)

Good

Dhara Patva

Reviewed on 10-02-2024

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(5/5)

Very good customer approach

Ketan Sarkar

Reviewed on 20-01-2024

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(5/5)

Best experience Got Discount on medicine

Krushnapalsinh Rathod

Reviewed on 30-11-2023

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(5/5)

Best cooperation

Chirag Patel

Reviewed on 01-02-2024

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(5/5)


Marketer / Manufacturer Details

SHILPA MEDICARE LTD

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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