CITAZA 100MG INJECTION
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CITAZA 100MG INJECTION
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CITAZA 100MG INJECTION

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CITAZA 100MG INJECTION

By CELON LABORATORIES LTD

MRP

3840

₹2454

36.09 % OFF

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Product DetailsArrow

About CITAZA 100MG INJECTION

  • CITAZA 100MG INJECTION is a medication primarily used for the treatment of Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) in adult patients.
  • It is specifically indicated for individuals who are deemed unsuitable candidates for stem cell transplantation. Stem cell transplant is a complex procedure and may not be a viable option for all patients due to various health-related factors.
  • Myelodysplastic Syndromes are a group of disorders where the bone marrow fails to produce sufficient numbers of healthy and functional blood cells. This deficiency can lead to anemia, increased susceptibility to infections, and bleeding tendencies.
  • Acute Myeloid Leukemia is a rapidly progressing cancer of the bone marrow characterized by the overproduction of immature blood cells that flood the bloodstream. These abnormal cells disrupt the normal production of healthy blood cells, leading to severe health complications.
  • CITAZA 100MG INJECTION works by affecting the DNA in cells within the bone marrow, which can help the bone marrow resume healthy blood cell production. It aims to control the growth and spread of cancerous cells in AML and improves blood cell production in MDS.
  • This medicine is usually administered by a healthcare professional. It is important to adhere to the prescribed dosage and schedule for optimal therapeutic effects and to minimize potential side effects. Regular monitoring of blood counts and other relevant parameters is necessary during treatment to assess response and manage any adverse reactions.
  • Treatment with CITAZA 100MG INJECTION is determined by medical professionals after assessing the patient's health condition and medical history.

Uses of CITAZA 100MG INJECTION

  • Treatment of Acute Myeloid Leukemia with 20-30% blasts in patients who are not eligible for Hematopoietic stem cell transplant. This treatment option is specifically for individuals with Acute Myeloid Leukemia where blast counts fall within the range of 20-30%, and who, due to various health factors, cannot undergo a Hematopoietic stem cell transplant. The goal is to manage the disease and improve quality of life.
  • Intermediate-2 and High-risk Myelodysplastic syndrome (MDS). This refers to Myelodysplastic syndromes that are classified as Intermediate-2 or High-risk based on prognostic scoring systems. These classifications indicate a greater likelihood of progression to Acute Myeloid Leukemia and a poorer overall prognosis, necessitating specific treatment strategies.

Side Effects of CITAZA 100MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, though not everyone experiences them. With CITAZA 100MG INJECTION, be aware of both serious and common potential reactions.

  • Unexpected bleeding, with blood in stool and urine
  • Fever
  • Pneumonia is characterized by chest pain or breathlessness.
  • Allergic reaction with symptoms of swelling of lips, itching, or rashes.
  • Seizures, loss of consciousness, severe headache, or bleeding in the brain
  • Frequent urination with pain or burning sensation
  • Disturbances in the blood count (RBC, WBC, Platelets)
  • Nausea, vomiting, diarrhea
  • Constipation
  • Tiredness
  • Skin reactions like redness and pain at the site of injection
  • Decreased appetite
  • Dizziness
  • Pain in extremities
  • Joint pain
  • Stomach pain
  • Headache
  • Sore nose and throat
  • Rashes and bruising

Safety Advice for CITAZA 100MG INJECTIONArrow

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Pregnancy

UNSAFE

CITAZA 100MG INJECTION could be harmful to the unborn fetus. Inform your physician if you are pregnant or planning to get pregnant.

Dosage of CITAZA 100MG INJECTIONArrow

  • CITAZA 100MG INJECTION should only be administered under the direct supervision of a qualified physician or healthcare professional. Self-administration is strongly discouraged due to the potential for complications and the need for careful monitoring.
  • The appropriate dosage of CITAZA 100MG INJECTION will be determined by your physician based on a comprehensive assessment of your individual needs. Factors such as your height, weight, overall health condition, and the specific medical condition being treated will all be taken into consideration to ensure the dosage is both safe and effective.
  • CITAZA 100MG INJECTION is typically administered via subcutaneous injection, meaning it is injected under the skin. Common injection sites include the thigh, stomach, or upper arm. Your healthcare provider will instruct you on the proper injection technique and the best site for administration.
  • It is crucial to adhere strictly to your physician's instructions regarding the dosage and frequency of CITAZA 100MG INJECTION. Do not attempt to adjust the dosage on your own, as this could have adverse effects. If you have any questions or concerns about your treatment plan, consult with your physician or pharmacist for clarification.

How to store CITAZA 100MG INJECTION?Arrow

  • Keep CITAZA 100MG INJ away from the reach of children and pets.
  • Store CITAZA 100MG INJ at room temperature.

Benefits of CITAZA 100MG INJECTIONArrow

  • In Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML), the abnormal proliferation of tumor cells stems from transcriptional repression, a process significantly influenced by DNA hypermethylation. This hypermethylation essentially silences genes that would normally regulate cell growth and differentiation, leading to uncontrolled cellular expansion characteristic of these cancers. Transcriptional repression involves proteins binding to DNA, either directly or indirectly, to suppress the transcription – or copying – of specific genes or sets of genes. This mechanism prevents the production of essential proteins that would otherwise inhibit tumor development.
  • CITAZA 100MG INJECTION, in its active form, exerts its therapeutic effect by directly interacting with both RNA and DNA within the body. This interaction disrupts the normal function of these nucleic acids, particularly in rapidly dividing cells, such as cancer cells. By interfering with RNA and DNA activity, CITAZA 100MG INJECTION effectively inhibits cell division and induces a toxic effect, ultimately leading to the death of cancerous cells. This targeted action helps to control the growth and spread of MDS and AML.
  • The drug's mechanism of action specifically targets the epigenetic modifications that drive tumor development in MDS and AML. By reversing or inhibiting DNA hypermethylation, CITAZA 100MG INJECTION aims to restore the expression of silenced genes, thereby promoting normal cellular function and differentiation. This approach represents a significant advancement in cancer therapy, as it directly addresses the underlying molecular mechanisms that contribute to disease progression. It is important to note that the drug's effectiveness can vary depending on the individual patient and the specific characteristics of their cancer.

How to use CITAZA 100MG INJECTIONArrow

  • CITAZA 100MG INJECTION should only be administered under the direct supervision and guidance of a qualified physician. Self-administration is strongly discouraged. The dosage will be meticulously determined by your physician, taking into account several crucial factors, including your height, weight, overall health status, and the specific medical condition being treated. It is imperative to adhere strictly to the prescribed dosage and administration schedule provided by your healthcare provider.
  • This medication is administered via subcutaneous injection, meaning it is injected beneath the skin. Common injection sites include the thigh, stomach (abdomen), or upper arm. Your physician or a trained healthcare professional will carefully select the most appropriate injection site and will provide detailed instructions on proper injection techniques. If you are administering the injection yourself, ensure you fully understand and follow these instructions to minimize the risk of complications.
  • It is crucial to maintain consistent injection sites and to rotate them regularly to prevent skin irritation or other localized reactions. Furthermore, it's important to observe the injection site for any signs of redness, swelling, pain, or infection. If you experience any adverse reactions, promptly consult with your physician. Regular monitoring by your healthcare provider is essential to assess your response to the medication and to make any necessary adjustments to your treatment plan.

FAQs

How to use CITAZA 100MG INJECTION?Arrow

Take CITAZA 100MG INJECTION only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. CITAZA 100MG INJECTION is administered under the skin of your thigh, stomach, or upper arm.

Does CITAZA 100MG INJECTION cause hair loss?Arrow

No, CITAZA 100MG INJECTION does not cause hair loss even after using it for a prolonged period of time.

How does CITAZA 100MG INJECTION work?Arrow

CITAZA 100MG INJECTION binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells.

Is CITAZA 100MG INJECTION chemotherapy?Arrow

Yes. CITAZA 100MG INJECTION is chemotherapy used in the treatment of cancers. It interferes with the cell's DNA synthesis and decreases growth and multiplication (cytotoxic effect).

What are the side effects of CITAZA 100MG INJECTION?Arrow

The common side effects of CITAZA 100MG INJECTION are Nausea, vomiting, diarrhea, constipation, tiredness, decreased appetite, rashes, redness of the skin, dizziness, joint pain, headache, sore throat, and nose.

Is it safe to drive after taking a CITAZA 100MG INJECTION?Arrow

It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking this medication.

Does CITAZA 100MG INJECTION interact with other drugs?Arrow

No significant interactions between CITAZA 100MG INJECTION and other drugs have been identified.

What should I tell my doctor before taking CITAZA 100MG INJECTION?Arrow

AZACITIDINE is the active pharmaceutical ingredient in CITAZA 100MG INJECTION.

What is CITAZA 100MG INJECTION used for?Arrow

CITAZA 100MG INJECTION is prescribed for the treatment of various oncological conditions.

How does CITAZA 100MG INJECTION help in cancer treatment?Arrow

CITAZA 100MG INJECTION interferes with the growth and spread of cancer cells, thereby aiding in cancer treatment.

References

Book Icon

K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, 60(4):721-741

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Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018

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Dr.Reddy’s Laboratories

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Ratings & Review

Good discounts available for all medicine.

Akash Patel

Reviewed on 01-12-2023

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(4/5)

Well satisfying products. Generic medicines are way cheaper and of very good quality. Staff is well behaved and knowledgeable.

khozema kaukawala

Reviewed on 08-09-2023

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(5/5)

Good service and affordable price I think best in medical

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Reviewed on 05-11-2022

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(5/5)

Best service always... Best staff ..thank u being over life part

Nisha Khan

Reviewed on 01-07-2023

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(5/5)

Good pharmacy

shashiprakash sharma

Reviewed on 20-08-2023

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(5/5)


Marketer / Manufacturer Details

CELON LABORATORIES LTD

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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