XPREZA 100MG INJECTION
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XPREZA 100MG INJECTION
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XPREZA 100MG INJECTION

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XPREZA 100MG INJECTION

By NATCO PHARMA LIMITED

MRP

₹

4015.47

₹2790

30.52 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About XPREZA 100MG INJECTION

  • XPREZA 100MG INJECTION is a medication primarily used in adults to treat Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML). It is specifically considered for patients who are not suitable candidates for stem cell transplantation.
  • Myelodysplastic Syndrome is a condition where the bone marrow fails to produce sufficient healthy blood cells due to impaired function. This can lead to various complications and health issues related to blood cell deficiencies.
  • Acute Myeloid Leukemia, on the other hand, is a type of cancer affecting the bone marrow. It is characterized by the release of immature blood cells into the bloodstream, disrupting normal blood cell production and function. XPREZA 100MG INJECTION aims to target and manage these conditions, providing a therapeutic option for patients who might not have other viable treatments.
  • This injection works by targeting specific mechanisms involved in the development and progression of MDS and AML, helping to restore normal blood cell production or slow down the proliferation of cancerous cells. The exact mechanism of action may vary, but it's designed to improve the overall health and well-being of patients with these conditions. It's essential to consult with a healthcare professional to determine if XPREZA 100MG INJECTION is the right treatment option based on individual health circumstances and disease severity.

Uses of XPREZA 100MG INJECTION

  • Treatment of Acute Myeloid Leukemia with 20-30% blasts in patients who are not eligible for Haemopoietic stem cell transplant. This involves managing the condition in individuals whose blast counts fall within a specific range but are unsuitable candidates for a stem cell transplant, focusing on alternative therapeutic strategies to control the disease.
  • Intermediate-2 and High-risk Myelodysplastic syndrome (MDS). This includes addressing cases of MDS that are classified as intermediate-2 or high-risk, requiring more aggressive treatment approaches due to the higher likelihood of progressing to acute leukemia.

Side Effects of XPREZA 100MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, though not everyone experiences them. Serious side effects include unexpected bleeding (with blood in stool and urine), fever, pneumonia (characterized by chest pain or breathlessness), allergic reaction (with symptoms like swelling of lips, itching, or rashes), seizures, loss of consciousness, severe headache, or bleeding in the brain, and frequent urination with pain or burning sensation.

  • Disturbances in the blood count (RBC, WBC, Platelets)
  • Nausea, vomiting, diarrhea
  • Constipation
  • Tiredness
  • Skin reactions like redness and pain at the site of injection
  • Decreased appetite
  • Dizziness
  • Pain in extremities
  • Joint pain
  • Stomach pain
  • Headache
  • Sore nose and throat
  • Rashes and bruising

Safety Advice for XPREZA 100MG INJECTIONArrow

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Pregnancy

UNSAFE

XPREZA 100MG INJECTION could be harmful to the unborn fetus. Inform your physician if you are pregnant or planning to get pregnant.

Dosage of XPREZA 100MG INJECTIONArrow

  • Always use XPREZA 100MG INJECTION under the direct supervision and guidance of a qualified healthcare professional. Self-administration without proper medical oversight can be risky and is not recommended. Your doctor will carefully determine the most appropriate dosage for you, taking into account several individual factors.
  • These factors include your height, your weight, and your overall health condition. These are crucial in determining the correct dosage to ensure the medication is both safe and effective for you. The physician will also consider any other existing medical conditions or medications you may be taking.
  • XPREZA 100MG INJECTION is administered via subcutaneous injection, which means it is injected under the skin. The injection site will typically be in one of three areas: the thigh, the stomach (abdomen), or the upper arm. Your healthcare provider will guide you on the best injection site and proper technique.
  • It's vital to follow your doctor's instructions precisely regarding the dosage, frequency, and administration of XPREZA 100MG INJECTION. If you have any questions or concerns, don't hesitate to ask your physician or a qualified healthcare professional.

How to store XPREZA 100MG INJECTION?Arrow

  • Keep XPREZA 100MG INJ away from the reach of children and pets.
  • Store XPREZA 100MG INJ at room temperature.

Benefits of XPREZA 100MG INJECTIONArrow

  • In Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML), the uncontrolled growth of tumor cells stems from a process called transcriptional repression, which is triggered by DNA hypermethylation. This means that certain genes, vital for normal cell function, are effectively silenced.
  • Transcriptional repression occurs when proteins attach themselves to DNA, either directly or indirectly, and interfere with the transcription process. Transcription is essentially the copying of a gene or a set of genes to create the instructions needed to build proteins. By blocking this process, these proteins prevent the gene from being expressed.
  • XPREZA 100MG INJECTION works by targeting RNA and DNA. Its active form binds to these nucleic acids and disrupts their activity, especially within rapidly dividing cells. This interference leads to a toxic effect specifically on cancer cells, effectively hindering their proliferation and spread.
  • Therefore, XPREZA 100MG INJECTION helps in managing MDS and AML by actively interfering in the multiplication of cancer cells and also helps in subsiding their growth.

How to use XPREZA 100MG INJECTIONArrow

  • Always use XPREZA 100MG INJECTION under the direct supervision of a qualified healthcare provider. Self-administration without proper guidance can be risky.
  • Your physician will determine the precise dosage of XPREZA 100MG INJECTION based on a comprehensive assessment of your individual needs, including your height, weight, overall health status, and the specific condition being treated. It is crucial to adhere to the prescribed dosage for optimal results.
  • XPREZA 100MG INJECTION is administered subcutaneously, meaning it is injected under the skin. The preferred injection sites include the outer area of your thigh, the abdomen (avoiding the area around the navel), or the upper arm. Your healthcare provider will instruct you on proper injection techniques.
  • Before each injection, inspect the solution for any particulate matter or discoloration. Do not use the solution if it appears cloudy or contains visible particles. Use a new syringe and needle for each injection to maintain sterility and prevent infection.
  • Follow your doctor's instructions carefully regarding the frequency and timing of injections. Consistency is key to achieving the desired therapeutic effect with XPREZA 100MG INJECTION.

FAQs

How to use XPREZA 100MG INJECTION?Arrow

Take XPREZA 100MG INJECTION only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. XPREZA 100MG INJECTION is administered under the skin of your thigh, stomach or upper arm.

Does XPREZA 100MG INJECTION cause hair loss?Arrow

No, XPREZA 100MG INJECTION does not cause hair loss even after using it for a prolonged period of time.

How does XPREZA 100MG INJECTION work?Arrow

XPREZA 100MG INJECTION binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells.

Is XPREZA 100MG INJECTION chemotherapy?Arrow

Yes, XPREZA 100MG INJECTION is chemotherapy, and it is used in the treatment of cancers. It interferes with the cell's DNA synthesis and decreases growth and multiplication (cytotoxic effect).

What are the side effects of XPREZA 100MG INJECTION?Arrow

The common side effects of XPREZA 100MG INJECTION are Nausea, vomiting, diarrhea, constipation, tiredness, decreased appetite, rashes, redness of the skin, dizziness, joint pain, headache, sore throat, and nose.

Is it safe to drive after taking an XPREZA 100MG INJECTION?Arrow

It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking this medication.

Does XPREZA 100MG INJECTION interact with other drugs?Arrow

There is no known interaction of XPREZA 100MG INJECTION with other drugs.

What precautions should I take while taking XPREZA 100MG INJECTION?Arrow

Inform the doctor if the patient has any allergy reactions, respiratory problems, kidney, liver, or heart problems, and medication taken for different medical conditions before taking this injection as they worsen the condition. Avoid using this injection if the patient is planning for pregnancy or during pregnancy and in breastfeeding mothers as this medicine causes harmful effects on the developing baby. Take this injection only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. It is administered under the skin of your thigh, stomach, or upper arm.

What is XPREZA 100MG INJECTION made of?Arrow

XPREZA 100MG INJECTION is made of AZACITIDINE.

For what conditions is XPREZA 100MG INJECTION prescribed?Arrow

XPREZA 100MG INJECTION is prescribed for Oncology related conditions.

References

Book Icon

K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, 60(4):721-741

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Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018

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Dr.Reddy’s Laboratories

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Ratings & Review

Medkart is very good for generic medicines. We can get low price and effective medicines. Staff of medkart is also good

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Reviewed on 23-05-2023

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वेरी गुड एक्सीलेंट

bhavtosh vyas

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Reviewed on 31-01-2024

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(5/5)

Good discounts available for all medicine.

Akash Patel

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Reviewed on 01-12-2023

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(4/5)

Medicines at affordable and discounted rates... Good service...

George Thomas

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Reviewed on 24-01-2024

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(5/5)

Generic medicines at reasonable rates.

Narmawala Anzar Mo.Ilyas

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Reviewed on 22-04-2024

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(5/5)


Marketer / Manufacturer Details

NATCO PHARMA LIMITED

Country of Origin -

India

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30.52 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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