AZALIVE 100MG INJECTION
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AZALIVE 100MG INJECTION
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AZALIVE 100MG INJECTION

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AZALIVE 100MG INJECTION

By ABBOTT HEALTH CARE PRIVATE LIMITED

MRP

5043.11

₹3746

25.72 % OFF

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Product DetailsArrow

About AZALIVE 100MG INJECTION

  • AZALIVE 100MG INJECTION is a medication specifically used to treat adults diagnosed with Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML). It is generally prescribed when patients are not suitable candidates for stem cell transplants. Myelodysplastic Syndrome is a condition where the bone marrow malfunctions, leading to the insufficient production of healthy and functional blood cells.
  • In simpler terms, the bone marrow, which is responsible for creating blood cells, doesn't work as it should. This results in a deficiency of healthy blood cells that are vital for the body's normal functions. Acute Myeloid Leukemia, on the other hand, is a form of cancer affecting the bone marrow. This cancer is characterized by the release of immature blood cells into the bloodstream.
  • These incompletely formed blood cells disrupt the normal functioning of the blood and can lead to various health complications. AZALIVE 100MG INJECTION aims to address these conditions by targeting the underlying issues in the bone marrow and blood cell production, offering a potential treatment option for patients who cannot undergo stem cell transplantation.

Uses of AZALIVE 100MG INJECTION

  • Treatment of Acute Myeloid Leukemia with 20-30% blasts in patients who are not eligible for Hematopoietic stem cell transplant. This treatment option is specifically for individuals whose health condition prevents them from undergoing a stem cell transplant, aiming to manage the leukemia and improve their quality of life.
  • Intermediate-2 and High-risk Myelodysplastic syndrome (MDS). This refers to a category of MDS characterized by a higher likelihood of progressing to acute leukemia and a poorer overall prognosis. Management strategies focus on mitigating symptoms and slowing disease progression.

Side Effects of AZALIVE 100MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious side effects may include unexpected bleeding (with blood in stool and urine), fever, pneumonia (characterized by chest pain or breathlessness), allergic reaction (with symptoms of swelling of lips, itching, or rashes), seizures, loss of consciousness, severe headache or bleeding in the brain, and frequent urination with pain or burning sensation. Common side effects may include disturbances in the blood count (RBC, WBC, Platelets), nausea, vomiting, diarrhea, constipation, tiredness, skin reaction like redness and pain at the site of injection, decreased appetite, dizziness, pain in extremities, joint pain, stomach pain, headache, sore nose and throat, rashes and bruising.

  • Unexpected bleeding, with blood in stool and urine
  • Fever
  • Pneumonia, characterized by chest pain or breathlessness.
  • Allergic reaction with symptoms of swelling of lips, itching or rashes.
  • Seizures, loss of consciousness, severe headache or bleeding in the brain
  • Frequent urination with pain or burning sensation
  • Disturbances in the blood count (RBC, WBC, Platelets)
  • Nausea, vomiting, diarrhea
  • Constipation
  • Tiredness
  • Skin reaction like redness and pain at the site of injection
  • Decreased appetite
  • Dizziness
  • Pain in extremities
  • Joint pain
  • Stomach pain
  • Headache
  • Sore nose and throat
  • Rashes and bruising

Safety Advice for AZALIVE 100MG INJECTIONArrow

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Pregnancy

UNSAFE

AZALIVE 100MG INJECTION could be harmful to the unborn fetus. Inform your physician if you are pregnant or planning to get pregnant.

Dosage of AZALIVE 100MG INJECTIONArrow

  • AZALIVE 100MG INJECTION should only be administered under the direct supervision of a qualified physician. This ensures that the medication is given safely and effectively, with appropriate monitoring for any potential side effects. It is crucial to adhere strictly to your physician's instructions regarding the use of this medication.
  • The precise dosage of AZALIVE 100MG INJECTION will be determined by your physician based on a comprehensive assessment of your individual needs. Factors such as your height, weight, overall health condition, and the specific condition being treated will all be taken into consideration when determining the appropriate dose. This personalized approach ensures that you receive the optimal amount of medication for your situation.
  • AZALIVE 100MG INJECTION is administered via subcutaneous injection, meaning it is injected under the skin. The injection site will typically be on the thigh, stomach, or upper arm. Your physician or a trained healthcare professional will administer the injection using proper technique to minimize discomfort and ensure proper absorption of the medication.
  • It is important to follow your physician's guidance on the frequency and timing of injections. Do not attempt to self-administer AZALIVE 100MG INJECTION unless you have been properly trained and instructed by a healthcare professional. Improper administration can lead to complications or reduced effectiveness of the medication.

How to store AZALIVE 100MG INJECTION?Arrow

  • Keep AZALIVE 100MG INJ away from the reach of children and pets.
  • Store AZALIVE 100MG INJ at room temperature.

Benefits of AZALIVE 100MG INJECTIONArrow

  • In Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML), the uncontrolled growth of tumor cells is often linked to a process called transcriptional repression. This occurs when genes that normally regulate cell growth and differentiation are silenced due to a mechanism known as DNA hypermethylation. Essentially, DNA hypermethylation involves the addition of methyl groups to DNA, which can prevent the necessary genes from being expressed. This transcriptional repression involves proteins that attach to the DNA, either directly or indirectly, to modify or entirely block the copying of certain genes or groups of genes.
  • AZALIVE 100MG INJECTION works by interfering with the activity of RNA and DNA within rapidly dividing cells. The active form of this medication binds to both RNA and DNA, disrupting their normal functions. This disruption leads to a toxic effect specifically targeting cancer cells, ultimately hindering their proliferation and contributing to the overall treatment of MDS and AML. By integrating into the DNA and RNA, it causes structural damage that stalls cell division and eventually leads to cell death. The drug is particularly effective on fast-growing cancer cells.
  • The mechanism of AZALIVE 100MG INJECTION offers a vital therapeutic strategy for managing MDS and AML by targeting the underlying molecular processes that promote cancerous cell growth. The medication's interference with RNA and DNA function is key to its efficacy in inhibiting the proliferation of tumor cells.

How to use AZALIVE 100MG INJECTIONArrow

  • Always use AZALIVE 100MG INJECTION exactly as your doctor tells you. The dosage will be determined by your doctor, taking into account factors such as your height, weight, and overall health condition. It is crucial to adhere to their prescribed instructions for the best possible outcome.
  • AZALIVE 100MG INJECTION is administered via subcutaneous injection, which means it's injected under the skin. Your doctor or nurse will likely administer the injection, but they may also train you to administer it yourself at home. Ensure you fully understand the injection technique before attempting self-administration.
  • The injection site is typically on the thigh, stomach, or upper arm. Rotate the injection site each time you administer AZALIVE 100MG INJECTION to avoid irritation or discomfort in the same area. Do not inject into areas where the skin is bruised, tender, hard, or scarred.
  • It is vital to adhere to all instructions given by your physician. If anything is unclear please make sure you confirm with them. Always make sure you have the correct dosage and you know how to administer.
  • If you have any concerns about administering AZALIVE 100MG INJECTION, or if you experience any unexpected side effects, consult with your doctor or pharmacist immediately.

FAQs

How to use AZALIVE 100MG INJECTION?Arrow

Take AZALIVE 100MG INJECTION only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. AZALIVE 100MG INJECTION is administered under the skin of your thigh, stomach, or upper arm.

Does AZALIVE 100MG INJECTION cause hair loss?Arrow

No, AZALIVE 100MG INJECTION does not cause hair loss even after using it for a prolonged period of time.

How does AZALIVE 100MG INJECTION work?Arrow

AZALIVE 100MG INJECTION binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells.

Is AZALIVE 100MG INJECTION chemotherapy?Arrow

Yes. AZALIVE 100MG INJECTION is chemotherapy and it is used in the treatment of cancers. It interferes with the cell's DNA synthesis and decreases growth and multiplication (cytotoxic effect).

What are the side effects of AZALIVE 100MG INJECTION?Arrow

The common side effects of AZALIVE 100MG INJECTION are nausea, vomiting, diarrhea, constipation, tiredness, decreased appetite, rashes, redness of skin, dizziness, joint pain, headache, sore throat and nose.

Is it safe to drive after taking an AZALIVE 100MG INJECTION?Arrow

It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking this medication.

NULL interaction of AZALIVE 100MG INJECTION with other drungsArrow

Consult a doctor for information on the interaction of AZALIVE 100MG INJECTION with other drugs.

What advice should be followed while taking AZALIVE 100MG INJECTION?Arrow

Inform the doctor if the patient has any allergy reactions, respiratory problems, kidney, liver, or heart problems, and medication taken for different medical conditions before taking this injection as they worsen the condition. Avoid using this injection if the patient is planning for pregnancy or during pregnancy and in breastfeeding mothers as this medicine causes harmful effects in the developing baby. Take this injection only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. It is administered under the skin of your thigh, stomach or upper arm.

Which molecule/combination is used for making AZALIVE 100MG INJECTION?Arrow

AZACITIDINE is molecule/combination used for making AZALIVE 100MG INJECTION.

For what type of cancer AZALIVE 100MG INJECTION is prescribed?Arrow

AZALIVE 100MG INJECTION is prescribed for Oncology related ailments/diseases/conditions.

References

Book Icon

K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, 60(4):721-741

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Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018

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Dr.Reddy’s Laboratories

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Marketer / Manufacturer Details

ABBOTT HEALTH CARE PRIVATE LIMITED

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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