AZATIREL 100MG INJECTION
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AZATIREL 100MG INJECTION
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AZATIREL 100MG INJECTION

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AZATIREL 100MG INJECTION

By RELIANCE LIFE SCIENCES

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Product DetailsArrow

About AZATIREL 100MG INJECTION

  • AZATIREL 100MG INJECTION is a medication specifically designed for adult patients diagnosed with Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) who are not suitable candidates for stem cell transplantation. Myelodysplastic Syndromes are a group of disorders where the bone marrow fails to produce sufficient healthy blood cells due to impaired functionality. This can lead to various complications, including anemia, increased risk of infections, and bleeding problems.
  • Acute Myeloid Leukemia (AML) is an aggressive form of bone marrow cancer characterized by the rapid proliferation of immature blood cells into the bloodstream. These abnormal cells disrupt the production of normal blood cells, leading to serious health issues. AZATIREL 100MG INJECTION works by targeting these abnormal cells and helping to restore normal blood cell production, thus improving overall health and quality of life for patients with MDS and AML who cannot undergo stem cell transplantation.
  • This medication offers a therapeutic option for managing these conditions and improving patient outcomes when stem cell transplant, a more intensive treatment, is not a viable option. Treatment with AZATIREL 100MG INJECTION should be closely monitored by a healthcare professional to ensure its effectiveness and manage any potential side effects.

Uses of AZATIREL 100MG INJECTION

  • Treatment of Acute Myeloid Leukemia, characterized by the presence of 20-30% blasts, specifically in patients for whom a Hematopoietic Stem Cell Transplant is not a viable option.
  • Management of Intermediate-2 and High-Risk Myelodysplastic Syndrome (MDS). This includes therapeutic strategies to address the challenges associated with these advanced stages of MDS.

Side Effects of AZATIREL 100MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. It's important to be aware of both serious and common side effects associated with medications like AZATIREL 100MG INJECTION.

Safety Advice for AZATIREL 100MG INJECTIONArrow

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Pregnancy

UNSAFE

AZATIREL 100MG INJECTION could be harmful to the unborn fetus. Inform your physician if you are pregnant or planning to get pregnant.

Dosage of AZATIREL 100MG INJECTIONArrow

  • AZATIREL 100MG INJECTION should only be administered under the direct supervision of a qualified physician. Self-administration is strongly discouraged due to the need for careful monitoring and dosage adjustments.
  • Your physician will determine the appropriate dosage based on a comprehensive assessment of your individual needs. This assessment will take into account several factors, including your height, weight, overall health condition, and the specific condition being treated.
  • The injection is typically administered subcutaneously, meaning it's injected under the skin. Common injection sites include the thigh, stomach (abdomen), or upper arm. Your physician or nurse will instruct you on the proper injection technique if self-administration is deemed appropriate.
  • It is crucial to follow your physician's instructions meticulously regarding the dosage and frequency of injections. Do not alter the dosage or stop treatment without consulting your physician, as this could have adverse effects on your health and the effectiveness of the treatment.
  • If you have any questions or concerns about AZATIREL 100MG INJECTION or its administration, please do not hesitate to contact your physician or healthcare provider. They are the best resource for addressing your individual needs and ensuring the safe and effective use of this medication.

How to store AZATIREL 100MG INJECTION?Arrow

  • Keep AZATIREL 100MG INJ away from the reach of children and pets.
  • Store AZATIREL 100MG INJ at room temperature.

Benefits of AZATIREL 100MG INJECTIONArrow

  • In Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML), the uncontrolled growth of tumor cells stems from a disruption in the normal process of gene expression. This disruption is often triggered by DNA hypermethylation, a phenomenon where excessive methyl groups attach to DNA, leading to transcriptional repression. Transcriptional repression involves proteins binding to DNA, either directly or indirectly, to suppress the copying or 'transcription' of specific genes or sets of genes. This silencing of genes that normally regulate cell growth and differentiation contributes to the development and progression of MDS and AML.
  • AZATIREL 100MG INJECTION, in its active form, interacts directly with both RNA and DNA. This interaction disrupts the normal function of these nucleic acids, particularly within rapidly dividing cells, such as cancer cells. By interfering with RNA and DNA activity, AZATIREL 100MG INJECTION exerts a cytotoxic effect, meaning it is toxic to cancer cells. This toxicity helps to slow down or halt the proliferation of cancerous cells in MDS and AML, providing a therapeutic benefit.
  • The mechanism of AZATIREL 100MG INJECTION's action is complex and targets fundamental processes necessary for cancer cell survival and division. By interrupting the cell's genetic machinery, it can induce cell death or prevent further replication, ultimately aiming to reduce the burden of cancerous cells within the body.

How to use AZATIREL 100MG INJECTIONArrow

  • Only take AZATIREL 100MG INJECTION under the direct supervision and guidance of your physician. They are best equipped to assess your individual needs and monitor your progress throughout the treatment.
  • The dosage of AZATIREL 100MG INJECTION will be determined by your physician based on a thorough evaluation of your specific condition, taking into account factors such as your height, weight, overall health status, and the severity of your condition. It is crucial to adhere to the prescribed dosage and administration schedule provided by your physician.
  • AZATIREL 100MG INJECTION is administered via subcutaneous injection, meaning it is injected under the skin. The injection site will typically be in areas such as the thigh, stomach, or upper arm. Your physician or a trained healthcare professional will demonstrate the correct injection technique to ensure proper administration and minimize any potential discomfort.
  • It's important to maintain consistency in the injection site and follow any specific instructions given by your healthcare provider regarding site rotation or other considerations.
  • If you have any questions or concerns regarding the administration of AZATIREL 100MG INJECTION, do not hesitate to consult your physician or pharmacist for clarification and guidance.

FAQs

How to use AZATIREL 100MG INJECTION?Arrow

Take AZATIREL 100MG INJECTION only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. AZATIREL 100MG INJECTION is administered under the skin of your thigh, stomach, or upper arm.

Does AZATIREL 100MG INJECTION cause hair loss?Arrow

No, AZATIREL 100MG INJECTION does not cause hair loss even after using it for a prolonged period of time.

How does AZATIREL 100MG INJECTION work?Arrow

AZATIREL 100MG INJECTION binds to RNA and DNA, interrupts their activity in actively multiplying cells and exhibits a toxic effect on cancer cells.

Is AZATIREL 100MG INJECTION chemotherapy?Arrow

Yes. AZATIREL 100MG INJECTION is chemotherapy, and it is used in the treatment of cancers. It interferes with the cell's DNA synthesis and decreases growth and multiplication (cytotoxic effect).

What are the side effects of AZATIREL 100MG INJECTION?Arrow

The common side effects of AZATIREL 100MG INJECTION are Nausea, vomiting, diarrhea, constipation, tiredness, decreased appetite, rashes, redness of the skin, dizziness, joint pain, headache, sore throat and nose.

Is it safe to drive after taking an AZATIREL 100MG INJECTION?Arrow

It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking this medication.

NULL interaction of AZATIREL 100MG INJECTION with other drungsArrow

There is no known interaction of AZATIREL 100MG INJECTION with other drugs.

What should I tell my doctor before taking AZATIREL 100MG INJECTION?Arrow

Inform the doctor if the patient has any allergy reactions, respiratory problems, kidney, liver, or heart problems, and medication taken for different medical conditions before taking this injection as they worsen the condition. Avoid using this injection if the patient is planning for pregnancy or during pregnancy and in breastfeeding mothers as this medicine causes harmful effects in the developing baby. Take this injection only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. It is administered under the skin of your thigh, stomach or upper arm.

What molecule/combination is used for making AZATIREL 100MG INJECTION?Arrow

AZACITIDINE is molecule/combination used for making AZATIREL 100MG INJECTION.

What is the use of AZATIREL 100MG INJECTION in Oncology?Arrow

AZATIREL 100MG INJECTION is used in Oncology for the treatment of cancers. It helps in preventing the growth and spread of cancer cells.

References

Book Icon

K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, 60(4):721-741

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Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018

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Dr.Reddy’s Laboratories

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Ratings & Review

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Pravas Ranjan Acharya

Reviewed on 24-05-2023

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(2/5)

Very good and quik responce for all medicines

Binal Doshi

Reviewed on 03-01-2023

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Find the medicine which was quite hard to find in the vicinity

devnarayan yadav

Reviewed on 06-12-2022

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Same day dilevery available, Urgent response, Free home delivery above 500

Vikas Yadav

Reviewed on 09-07-2023

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(5/5)

Good Service and Price

Pranit Parmar

Reviewed on 22-11-2022

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(5/5)


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RELIANCE LIFE SCIENCES

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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