AZADINE INJECTION
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AZADINE INJECTION
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AZADINE INJECTION

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AZADINE INJECTION

By INTAS PHARMACEUTICALS LIMITED

MRP

4780.5

₹3729

22 % OFF

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Product Details
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About AZADINE INJECTION

  • AZADINE INJECTION is a medication prescribed for adults diagnosed with certain types of blood and bone marrow disorders. Its primary uses are in treating Myelodysplastic Syndromes (MDS) and a specific type of blood cancer known as Acute Myeloid Leukemia (AML). This injection is particularly important for patients who may not be suitable candidates for other treatments like a stem cell transplant.
  • Myelodysplastic Syndromes, or MDS, are conditions where the bone marrow doesn't produce enough healthy blood cells (like red cells, white cells, and platelets). This happens because the bone marrow itself isn't functioning correctly. Acute Myeloid Leukemia (AML), on the other hand, is a cancer that starts in the bone marrow. It causes the bone marrow to make too many abnormal white blood cells which don't mature properly. These abnormal cells can build up in the bone marrow and blood, interfering with the production and function of healthy blood cells. AZADINE INJECTION helps to improve the production of healthy blood cells in MDS and works against the abnormal cancer cells in AML.

Uses of AZADINE INJECTION

  • For patients with Acute Myeloid Leukemia (AML) who have 20-30% blast cells and cannot undergo a Haemopoietic stem cell transplant, this treatment is indicated.
  • Treatment for Myelodysplastic syndromes (MDS) identified as Intermediate-2 or High-risk.

Side Effects of AZADINE INJECTION
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Side effects are unwanted symptoms caused by medicines. Not everyone gets them. The following are potential side effects of AZADINE INJECTION.

Safety Advice for AZADINE INJECTION
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Pregnancy

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AZADINE INJECTION could be harmful to the unborn fetus. Inform your physician if you are pregnant or planning to get pregnant.

Dosage of AZADINE INJECTION
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  • It is crucial to receive AZADINE INJECTION strictly under the care and guidance of your doctor. This medication is powerful and its administration requires professional medical supervision to ensure it is safe and effective for you. Your doctor will determine the correct dose of AZADINE INJECTION specifically for your needs. They will carefully consider several factors, including your overall health status, your body weight, and your height. This personalized approach ensures that the treatment is tailored to your individual condition. AZADINE INJECTION is given as an injection just under the skin (subcutaneously). The common sites for this injection are the fatty tissue areas of your thigh, stomach (abdomen), or upper arm. Always follow your doctor's instructions regarding where and how the injection should be given.

How to store AZADINE INJECTION?
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  • Keep AZADINE 100MG INJ away from the reach of children and pets.
  • Store AZADINE 100MG INJ at room temperature.

Benefits of AZADINE INJECTION
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  • In conditions like Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML), the development and growth of tumor cells are often linked to a process called transcriptional repression. This happens when normal instructions within our cells, which are stored in our DNA as genes, get effectively silenced or blocked. Think of it like tiny chemical "sticky tags" or markers attaching to the DNA through a process called hypermethylation. These sticky tags prevent the cell's machinery from reading the genes properly. Transcriptional repression is the actual shutting down of gene activity because these proteins or tags bind to the DNA, controlling whether a gene can be copied or not. Genes that are crucial for normal cell function, controlling growth, and even telling damaged cells to stop dividing are wrongly switched off. AZADINE INJECTION is a medication used to treat these conditions. Its active form works by being incorporated into the DNA and RNA of rapidly dividing cells. This incorporation disrupts the normal function of these molecules and interferes with the cell's ability to repair or replicate its genetic material properly. Crucially, it can also influence the hypermethylation process, potentially helping to remove those blocking sticky tags and allow important genes to become active again. By disrupting the uncontrolled multiplication of cancer cells and potentially restoring some normal gene activity, AZADINE INJECTION exerts a toxic effect on these tumor cells, helping to manage MDS and AML.

How to use AZADINE INJECTION
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  • AZADINE INJECTION should always be administered strictly under the guidance and supervision of a qualified physician. This is crucial because your doctor needs to carefully assess your individual health status before determining the correct dosage for you. The specific amount of AZADINE INJECTION prescribed will depend on various factors, including your height, weight, overall health condition, and how your body is responding to treatment. The injection itself is typically given just under the skin, a method known as subcutaneous administration. Common areas for this include the thigh, stomach area (abdomen), or the upper arm. It is essential to follow your doctor's instructions precisely regarding the dosage schedule and administration site. Your physician will ensure the injection is given correctly and safely, and can monitor you for any potential side effects. Never attempt to administer this injection yourself or deviate from the prescribed plan without consulting your doctor.

FAQs

How to use AZADINE INJECTION?

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Take AZADINE INJECTION only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. AZADINE INJECTION is administered under the skin of your thigh, stomach, or upper arm.

Does AZADINE INJECTION cause hair loss?

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No, AZADINE INJECTION does not cause hair loss even after using it for a prolonged period of time.

How does AZADINE INJECTION work?

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AZADINE INJECTION binds to RNA and DNA, interrupts their activity in actively multiplying cells and exhibits a toxic effect on cancer cells.

Is AZADINE INJECTION chemotherapy?

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Yes. AZADINE INJECTION is chemotherapy, and it is used in the treatment of cancers. It interferes with the cell's DNA synthesis and decreases growth and multiplication (cytotoxic effect).

What are the side effects of AZADINE INJECTION?

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The common side effects of AZADINE INJECTION are Nausea, vomiting, diarrhea, constipation, tiredness, decreased appetite, rashes, redness of the skin, dizziness, joint pain, headache, sore throat and nose.

Is it safe to drive after taking AZADINE INJECTION?

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It is unsafe to drive after taking AZADINE INJECTION as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking this medication.

Does AZADINE INJECTION interact with other medicines?

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Inform your doctor about all the medications you are currently taking before starting AZADINE INJECTION.

What precautions should I take before using AZADINE INJECTION?

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Inform your doctor if you have any allergy reactions, respiratory problems, kidney, liver, or heart problems. Avoid using AZADINE INJECTION if you are planning for pregnancy, are pregnant, or are breastfeeding.

What is the main ingredient in AZADINE INJECTION?

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The main ingredient in AZADINE INJECTION is Azacitidine.

What is AZADINE INJECTION used for?

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AZADINE INJECTION is used to treat certain types of cancer. It is an anti-cancer medication.

References

Book Icon

K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, [May 2003], 60(4):721-741

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Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018

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Dr.Reddy’s Laboratories,

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Marketer / Manufacturer Details

INTAS PHARMACEUTICALS LIMITED

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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