AZAFECT 100MG INJECTION
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AZAFECT 100MG INJECTION
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AZAFECT 100MG INJECTION

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AZAFECT 100MG INJECTION

By AUREATE HEALTHCARE PRIVATE LIMITED

MRP

3900

₹1818

53.38 % OFF

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Product DetailsArrow

About AZAFECT 100MG INJECTION

  • AZAFECT 100MG INJECTION is a medication prescribed for adult patients diagnosed with Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML), particularly when they are not suitable candidates for stem cell transplantation. This medication aims to help manage these conditions and improve the patient's overall well-being.
  • Myelodysplastic Syndrome (MDS) is a condition where the bone marrow, responsible for producing blood cells, malfunctions and fails to produce healthy and functional blood cells. This can lead to various complications due to the deficiency of different types of blood cells.
  • Acute Myeloid Leukemia (AML) is a type of cancer affecting the bone marrow. It is characterized by the rapid proliferation and release of immature blood cells into the bloodstream. These abnormal cells disrupt the production of normal blood cells, leading to severe health problems.
  • AZAFECT 100MG INJECTION works by targeting the abnormal cells in MDS and AML, helping to restore normal blood cell production and reduce the severity of the disease. It is crucial to follow the prescribed dosage and treatment plan provided by your healthcare professional for the best possible outcome.

Uses of AZAFECT 100MG INJECTION

  • Treatment of Acute Myeloid Leukemia, characterized by 20-30% blasts, specifically in patients deemed ineligible for Haemopoietic stem cell transplant due to age, comorbidities, or other factors.
  • Management of Intermediate-2 and High-risk Myelodysplastic Syndrome (MDS), addressing the challenges associated with these advanced stages of the disease.

Side Effects of AZAFECT 100MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Unexpected bleeding, with blood in stool and urine
  • Fever
  • Pneumonia, characterized by chest pain or breathlessness.
  • Allergic reaction with symptoms of swelling of lips, itching or rashes.
  • Seizures, loss of consciousness, severe headache or bleeding in the brain
  • Frequent urination with pain or burning sensation
  • Disturbances in the blood count (RBC, WBC, Platelets)
  • Nausea, vomiting, diarrhea
  • Constipation
  • Tiredness
  • Skin reaction like redness and pain at the site of injection
  • Decreased appetite
  • Dizziness
  • Pain in extremities
  • Joint pain
  • Stomach pain
  • Headache
  • Sore nose and throat
  • Rashes and bruising

Safety Advice for AZAFECT 100MG INJECTIONArrow

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Pregnancy

UNSAFE

AZAFECT 100MG INJECTION could be harmful to the unborn fetus. Inform your physician if you are pregnant or planning to get pregnant.

Dosage of AZAFECT 100MG INJECTIONArrow

  • It is crucial to receive AZAFECT 100MG INJECTION only under the direct and careful supervision of a qualified physician. Self-administration is strongly discouraged.
  • Your physician holds the expertise to determine the most appropriate dosage for you, taking into careful consideration your individual parameters such as your height, your weight, and your overall general health condition. This personalized approach ensures the medication is both safe and effective.
  • AZAFECT 100MG INJECTION is administered via a subcutaneous injection, meaning it is injected just under the skin. Common injection sites include the outer area of your thigh, the skin of your stomach (abdomen), or the upper arm. Your physician or a trained healthcare professional will guide you on proper injection techniques if self-administration becomes necessary.
  • The frequency and timing of the injections will also be determined by your physician based on your specific medical needs and response to the treatment. It's important to strictly adhere to the prescribed schedule for optimal results and to minimize potential side effects.

How to store AZAFECT 100MG INJECTION?Arrow

  • Keep AZAFECT 100MG INJ away from the reach of children and pets.
  • Store AZAFECT 100MG INJ at room temperature.

Benefits of AZAFECT 100MG INJECTIONArrow

  • In Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML), the uncontrolled proliferation of tumor cells stems from a process called transcriptional repression. This repression occurs due to hypermethylation of DNA, a chemical modification that essentially silences genes.
  • Transcriptional repression involves proteins that directly or indirectly bind to DNA, thereby controlling the transcription, or copying, of specific genes or sets of genes. This control mechanism is disrupted in MDS and AML, leading to the abnormal growth of cancer cells.
  • AZAFECT 100MG INJECTION works by interfering with this process. Its active form binds to both RNA and DNA, disrupting their function particularly in rapidly dividing cells. This disruption leads to a toxic effect specifically targeting and destroying cancer cells.
  • By targeting the RNA and DNA of rapidly dividing cells, AZAFECT 100MG INJECTION helps to restore normal blood cell production and reduce the number of cancerous cells in the body. This mechanism of action makes it a crucial component in the treatment of MDS and AML.
  • Furthermore, AZAFECT 100MG INJECTION's impact on DNA hypermethylation can reverse the silencing of genes that regulate cell growth and differentiation, potentially restoring normal cellular function and slowing disease progression.

How to use AZAFECT 100MG INJECTIONArrow

  • Only take AZAFECT 100MG INJECTION under the direct supervision and guidance of your qualified physician. Self-administration is strongly discouraged, as your physician needs to assess your condition regularly to ensure the treatment is effective and safe.
  • The dosage of AZAFECT 100MG INJECTION will be precisely determined by your physician, taking into careful consideration several factors including your height, weight, overall health status, and the specific condition being treated. Adhering to the prescribed dosage is crucial for optimal therapeutic outcomes.
  • AZAFECT 100MG INJECTION is administered via subcutaneous injection, meaning it is injected under the skin. The common injection sites include the outer area of your thigh, the abdomen (stomach area), or the upper arm. Your healthcare provider will instruct you on the proper injection technique or administer the injection themselves.
  • It's important to maintain a consistent injection schedule as advised by your doctor to ensure a steady level of medication in your system. Do not alter the dosage or frequency of injections without consulting your physician.

FAQs

How to use AZAFECT 100MG INJECTION?Arrow

Take AZAFECT 100MG INJECTION only under the supervision of the physician. Doctors will decide the dose based on patient's height, weight, and general condition. AZAFECT 100MG INJECTION is administered under the skin of your thigh, stomach, or upper arm.

Does AZAFECT 100MG INJECTION cause hair loss?Arrow

No, AZAFECT 100MG INJECTION does not cause hair loss even after using it for a prolonged period of time.

How does AZAFECT 100MG INJECTION work?Arrow

AZAFECT 100MG INJECTION binds to RNA and DNA, interrupts their activity in actively multiplying cells and exhibits a toxic effect on cancer cells.

Is AZAFECT 100MG INJECTION chemotherapy?Arrow

Yes. AZAFECT 100MG INJECTION is chemotherapy, and it is used in the treatment of cancers. It interferes with the cell's DNA synthesis and decreases growth and multiplication (cytotoxic effect).

What are the side effects of AZAFECT 100MG INJECTION?Arrow

The common side effects of AZAFECT 100MG INJECTION are nausea, vomiting, diarrhea, constipation, tiredness, decreased appetite, rashes, redness of the skin, dizziness, joint pain, headache, sore throat, and nose.

Is it safe to drive after taking an AZAFECT 100MG INJECTION?Arrow

It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking this medication.

Does AZAFECT 100MG INJECTION interact with other drugs?Arrow

There are no known significant interactions of AZAFECT 100MG INJECTION with other drugs.

What precautions should I take while taking AZAFECT 100MG INJECTION?Arrow

Inform the doctor if the patient has any allergy reactions, respiratory problems, kidney, liver, or heart problems, and medication taken for different medical conditions before taking this injection as they worsen the condition. Avoid using this injection if the patient is planning for pregnancy or during pregnancy and in breastfeeding mothers as this medicine causes harmful effects on the developing baby. Take this injection only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. It is administered under the skin of your thigh, stomach, or upper arm.

Which molecule/combination is used for making AZAFECT 100MG INJECTION?Arrow

AZACITIDINE is molecule/combination used for making AZAFECT 100MG INJECTION.

For which ailments/diseases/conditions is AZAFECT 100MG INJECTION prescribed?Arrow

AZAFECT 100MG INJECTION is prescribed for ailments/diseases/conditions related to Oncology.

References

Book Icon

K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, 60(4):721-741

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Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018

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Dr.Reddy’s Laboratories

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(Translated by Google) My experience is very good discount, if you want to give extra medicine, return to the company is also available and on time per home delivery, after 2 days of ordering, other medicines are also available if the medicine is not your pass and it is clear that it is there. itna discount available (Original) My experience is very good discount Bhi achha dete extra medicine company me return Bhi ho jati hai aur time per home delivery Bhi hoti order dene ke 2din ke ander medicine available bhi ho jati hai yadi medicine na ho unke pass and clear bolte hai ki is per itna discount milega

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Reviewed on 20-10-2023

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Reviewed on 24-05-2023

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(2/5)

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Reviewed on 13-01-2024

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(5/5)


Marketer / Manufacturer Details

AUREATE HEALTHCARE PRIVATE LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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