CONIMAB 500MG/50ML INJECTION
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CONIMAB 500MG/50ML INJECTION
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CONIMAB 500MG/50ML INJECTION

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CONIMAB 500MG/50ML INJECTION

By CONCORD BIOTECH LTD

MRP

₹

47161

₹18999

59.71 % OFF

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Composition

RITUXIMAB 500 MG

Product DetailsArrow

About CONIMAB 500MG/50ML INJECTION

  • CONIMAB 500MG/50ML INJECTION contains rituximab as its active ingredient and is prescribed for various conditions in adults. It is administered alone or alongside other medications to combat non-Hodgkin’s lymphoma, a cancer affecting B-lymphocytes (a type of white blood cell), and chronic lymphocytic leukemia, a prevalent form of cancer impacting B-cells. Furthermore, it serves as a treatment for moderate-to-severe rheumatoid arthritis, an autoimmune disorder where the immune system mistakenly attacks joint tissues, when used in conjunction with methotrexate.
  • Additional applications include the treatment of granulomatosis with polyangiitis and microscopic polyangiitis, both conditions characterized by blood vessel inflammation primarily affecting the lungs and kidneys, in both adults and children aged two years and older. It is also indicated for managing moderate to severe pemphigus vulgaris, an autoimmune condition distinguished by painful blisters on the skin and the mucous membranes of the mouth, throat, nose, and genitals. Rituximab works by targeting the CD20 protein found on B cells, leading to their depletion and reducing the severity of autoimmune attacks or cancerous growth.
  • CONIMAB 500MG/50ML INJECTION is classified as an anti-CD20 monoclonal antibody. Exercise caution and avoid this injection if you have a known allergy to rituximab or any of its components, if you have a compromised immune system, or if you are currently battling a severe active infection. Before commencing treatment, inform your healthcare provider about any pre-existing heart conditions, heart failure, or breathing difficulties. Disclose any history of hepatitis B infection, as rituximab can reactivate the virus in some instances, potentially leading to severe complications. It's essential to use effective contraception during treatment and for 12 months following the final dose to prevent pregnancy. The use of CONIMAB 500MG/50ML INJECTION is generally not recommended during pregnancy and breastfeeding.
  • Common side effects associated with CONIMAB 500MG/50ML INJECTION may include infections of the blood, reduced red blood cell counts (anemia), dizziness, facial and bodily swelling (edema), itchy skin (pruritus), diarrhea, increased perspiration (hyperhidrosis), and fluctuations in blood pressure (either low or high). The medication carries the risk of severe infusion reactions during or within 24 hours of administration. Immediately notify your physician or a healthcare professional if you experience any symptoms indicative of an infusion reaction, such as elevated blood pressure, chest discomfort, headache, difficulty breathing, vomiting, skin rashes, or throat swelling. Regular monitoring and prompt management of any adverse reactions are crucial during treatment with rituximab.

Uses of CONIMAB 500MG/50ML INJECTION

  • Non-Hodgkin's Lymphoma (NHL): CONIMAB 500MG/50ML INJECTION is indicated for use in the treatment of various subtypes of Non-Hodgkin's Lymphoma, a type of cancer that begins in the lymphatic system. It targets specific cells involved in the lymphoma.
  • Chronic Lymphocytic Leukemia (CLL): CONIMAB 500MG/50ML INJECTION is also used in the management of Chronic Lymphocytic Leukemia, a slowly progressing cancer of the blood and bone marrow. It helps to control the growth and spread of cancerous cells.
  • Rheumatoid Arthritis: CONIMAB 500MG/50ML INJECTION plays a role in treating Rheumatoid Arthritis, an autoimmune disorder causing inflammation in the joints. It works by reducing the activity of the immune system to alleviate symptoms.
  • Granulomatosis with Polyangiitis or Microscopic Polyangiitis: CONIMAB 500MG/50ML INJECTION is utilized in treating Granulomatosis with Polyangiitis and Microscopic Polyangiitis, both of which are rare autoimmune diseases that affect blood vessels. It aids in reducing inflammation and damage to blood vessels.
  • Pemphigus Vulgaris: CONIMAB 500MG/50ML INJECTION is prescribed for Pemphigus Vulgaris, a rare autoimmune disease causing blistering of the skin and mucous membranes. It helps in controlling the immune response that leads to blister formation.

Side Effects of CONIMAB 500MG/50ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. CONIMAB 500MG/50ML INJECTION can cause some side effects.

  • Swelling in the face and body
  • Diarrhea and nausea
  • Itchy skin
  • Anemia
  • Muscle spasm
  • Headache
  • Urinary tract infection
  • Fever, chills, and shivering
  • Inflammation of nasal cavities
  • Cough, sore throat
  • Loss of hair
  • Increased or decreased blood pressure
  • Chest pain
  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Memory loss, trouble thinking, difficulty in walking

Safety Advice for CONIMAB 500MG/50ML INJECTIONArrow

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Pregnancy

UNSAFE

CONIMAB 500MG/50ML INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of CONIMAB 500MG/50ML INJECTIONArrow

  • CONIMAB 500MG/50ML INJECTION must only be administered by a qualified healthcare professional, such as a doctor or nurse, who has been trained in its use. It is crucial to avoid self-administration of this medication.
  • Prior to receiving CONIMAB 500MG/50ML INJECTION, you will be given pre-medications. These medications are administered to help minimize the potential for side effects associated with the injection. Your healthcare provider will carefully select these pre-medications based on your individual needs and medical history.
  • The dosage and duration of treatment with CONIMAB 500MG/50ML INJECTION will be determined by your doctor. This decision will be based on several factors, including the severity of your condition, your overall health, and any other medications you may be taking. It's essential to adhere strictly to the prescribed dosage and treatment schedule provided by your doctor.
  • CONIMAB 500MG/50ML INJECTION is administered as an intravenous infusion. During the infusion, you will be closely monitored for any adverse reactions or unwanted side effects. This monitoring allows the healthcare team to promptly address any concerns and ensure your safety throughout the treatment process.

How to store CONIMAB 500MG/50ML INJECTION?Arrow

  • Keep CONIMAB 500MG INJ away from the reach of children and pets.
  • Store CONIMAB 500MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of CONIMAB 500MG/50ML INJECTIONArrow

  • CONIMAB 500MG/50ML INJECTION is a specialized medication classified as a monoclonal antibody. It precisely targets the CD20 antigen found on the surface of B-lymphocytes, which are a specific type of white blood cell. These B-lymphocytes play a crucial role in various conditions, including Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL).
  • When CONIMAB 500MG/50ML INJECTION binds to these B-cells, it initiates a process of cell death, effectively reducing the population of these cells in NHL and CLL. This binding action also has a significant impact on the B-cells themselves, blocking their activation and subsequent growth. By disrupting these processes, CONIMAB 500MG/50ML INJECTION exerts its anticancer effects, helping to manage and control the progression of these conditions.
  • Furthermore, in the context of rheumatoid arthritis, CONIMAB 500MG/50ML INJECTION demonstrates its therapeutic benefits by inhibiting several key factors involved in the disease's inflammatory processes. It reduces the production of rheumatoid factor, a hallmark antibody associated with the condition. Additionally, it interferes with antigen presentation, a crucial step in the immune response, and inhibits T-cell activation, another key player in inflammation. Finally, it reduces the production of proinflammatory cytokines, which are signaling molecules that promote inflammation and contribute to the symptoms of rheumatoid arthritis.

How to use CONIMAB 500MG/50ML INJECTIONArrow

  • CONIMAB 500MG/50ML INJECTION is a medication that must be administered under the strict supervision of a qualified healthcare professional, such as a trained doctor or nurse. It is not intended for self-administration. Prior to receiving CONIMAB 500MG/50ML INJECTION, you will be given pre-medications to minimize the potential for side effects. These pre-medications are an important part of the treatment protocol and are designed to improve your comfort and safety during the infusion.
  • The dosage and duration of your treatment with CONIMAB 500MG/50ML INJECTION will be determined by your doctor, taking into account the severity of your condition and other individual factors. It's crucial to adhere to the prescribed treatment plan for optimal results.
  • CONIMAB 500MG/50ML INJECTION is administered intravenously as an infusion. During the infusion, you will be closely monitored for any adverse reactions or unwanted side effects. This close monitoring ensures that any potential issues are promptly addressed.
  • Please inform your doctor about any existing medical conditions or medications you are currently taking before starting the treatment with CONIMAB 500MG/50ML INJECTION. This will help the doctor to determine the correct treatment and dosage for you.
  • If you have any questions or concerns about CONIMAB 500MG/50ML INJECTION, please discuss them with your doctor or nurse. They are the best resource for information about your treatment.

FAQs

What are the special precautions I should be aware of before starting treatment with CONIMAB 500MG/50ML INJECTION?Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are CONIMAB 500MG/50ML INJECTION-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering CONIMAB 500MG/50ML INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during CONIMAB 500MG/50ML INJECTION?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the CONIMAB 500MG/50ML INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Is weight gain a side effect of CONIMAB 500MG/50ML INJECTION?Arrow

Weight gain has been reported in patients treated with CONIMAB 500MG/50ML INJECTION for non-hodgkin’s lymphoma.

Does CONIMAB 500MG/50ML INJECTION suppress the immune system?Arrow

Yes, it can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking CONIMAB 500MG/50ML INJECTION because it may cause drug-induced immunosuppression.

Does CONIMAB 500MG/50ML INJECTION interact with other drugs?Arrow

There is no known interaction of CONIMAB 500MG/50ML INJECTION with other drugs.

What advice should I take while taking CONIMAB 500MG/50ML INJECTION?Arrow

Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently because Conimab 500mg injection may cause drug-induced immunosuppression. Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease. Vaccination with live virus vaccines is not recommended before or during the treatment for patients with rheumatoid arthritis. Inform your healthcare professional if you have any active infection during the treatment.

What molecule/combination is used for making CONIMAB 500MG/50ML INJECTION?Arrow

RITUXIMAB is the molecule/combination used for making CONIMAB 500MG/50ML INJECTION.

For which ailments/diseases/conditions is CONIMAB 500MG/50ML INJECTION prescribed?Arrow

CONIMAB 500MG/50ML INJECTION is prescribed for ailments/diseases/conditions related to Oncology, Gastroenterology, Rheumatology, and Orthopaedics.

References

Book Icon

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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Ratings & Review

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Marketer / Manufacturer Details

CONCORD BIOTECH LTD

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India

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