IKGDAR 500MG/50ML INJECTION
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IKGDAR 500MG/50ML INJECTION
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IKGDAR 500MG/50ML INJECTION

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IKGDAR 500MG/50ML INJECTION

By CIPLA PHARMACEUTICAL COMPANY LIMITED

MRP

39865

₹31892

20 % OFF

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Product DetailsArrow

About IKGDAR 500MG/50ML INJECTION

  • IKGDAR 500MG/50ML INJECTION contains the active ingredient rituximab and is prescribed for various conditions in adults. It is used, either alone or in combination with other medications, for the treatment of non-Hodgkin's lymphoma, a cancer affecting white blood cells known as B-lymphocytes, and chronic lymphocytic leukemia, a common cancer that affects B-cells. Additionally, it's indicated for treating moderate-to-severe rheumatoid arthritis, an autoimmune disease where the immune system attacks the body's own joints, in conjunction with methotrexate in adults. Other applications include managing granulomatosis with polyangiitis or microscopic polyangiitis, conditions characterized by inflammation of blood vessels primarily affecting the lungs and kidneys, in both adults and children aged 2 years and older. Furthermore, it is employed in the treatment of moderate to severe pemphigus vulgaris, an autoimmune disorder causing painful blisters on the skin and mucous membranes of the mouth, throat, nose, and genitals.
  • IKGDAR 500MG/50ML INJECTION belongs to a class of medications called anti-CD20 monoclonal antibodies. It's crucial to avoid this injection if you have a known allergy to rituximab or any of its components, have a weakened immune system, or are currently experiencing a severe active infection. Before commencing treatment, inform your doctor about any pre-existing heart conditions, heart failure, or breathing difficulties. Disclose any history of hepatitis B infection to your doctor, as this infection can reactivate in some instances and potentially become severe. Pregnancy and breastfeeding are generally not recommended while using this injection.
  • Common side effects associated with IKGDAR 500MG/50ML INJECTION include blood infections, reduced red blood cell count, dizziness, facial and bodily swelling, itchy skin, diarrhea, increased sweating, and fluctuations in blood pressure (either low or high). If you are capable of becoming pregnant, it is essential to use effective contraceptive measures during treatment and for 12 months after the final dose. This medication may trigger severe infusion reactions during or within 24 hours of administration. Immediately notify your physician or healthcare professional if you experience any infusion-related reactions, such as elevated blood pressure, chest pain, headache, difficulty breathing, vomiting, skin rashes, or throat swelling. Regular monitoring and prompt reporting of any adverse effects are vital for ensuring patient safety and well-being throughout the treatment course.
  • It's important to discuss all medications you are taking with your doctor, including over-the-counter drugs and herbal supplements, to avoid any potential drug interactions. Routine blood tests may be required to monitor blood cell counts and liver function during treatment. Maintain open communication with your healthcare provider and attend all scheduled appointments. Staying hydrated by drinking plenty of fluids can help minimize some side effects. Your doctor will determine the appropriate dosage and frequency of administration based on your specific medical condition and response to treatment.

Uses of IKGDAR 500MG/50ML INJECTION

  • Non-Hodgkin's Lymphoma (NHL): A type of cancer that begins in the lymphatic system, where white blood cells called lymphocytes grow out of control. IKGDAR 500MG/50ML INJECTION can be used to treat certain types of NHL.
  • Chronic Lymphocytic Leukemia (CLL): A type of cancer of the blood and bone marrow. IKGDAR 500MG/50ML INJECTION may be used in the treatment of CLL to help slow the progression of the disease.
  • Rheumatoid Arthritis: A chronic inflammatory disorder affecting many joints, including those in the hands and feet. IKGDAR 500MG/50ML INJECTION can be prescribed to manage the symptoms and reduce inflammation associated with rheumatoid arthritis when other treatments haven't been effective.
  • Granulomatosis with Polyangiitis or Microscopic Polyangiitis: These are rare autoimmune diseases that cause inflammation of blood vessels. IKGDAR 500MG/50ML INJECTION is sometimes used to treat these conditions by suppressing the immune system.
  • Pemphigus Vulgaris: A rare autoimmune disorder that causes painful blisters on the skin and mucous membranes. IKGDAR 500MG/50ML INJECTION can be used as a treatment option to help control the immune response and reduce blister formation.

Side Effects of IKGDAR 500MG/50ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. With IKGDAR 500MG/50ML INJECTION, common side effects include swelling in the face and body. Serious side effects include increased or decreased blood pressure, chest pain, hypersensitivity reactions, Hepatitis B viral infection, and memory loss, trouble thinking, difficulty in walking.

  • Swelling in the face and body
  • Diarrhea and nausea
  • Itchy skin
  • Anemia
  • Muscle spasm
  • Headache
  • Urinary tract infection
  • Fever, chills, and shivering
  • Inflammation of nasal cavities
  • Cough, sore throat
  • Loss of hair
  • Increased or decreased blood pressure
  • Chest pain
  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Memory loss, trouble thinking, difficulty in walking

Safety Advice for IKGDAR 500MG/50ML INJECTIONArrow

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Pregnancy

UNSAFE

IKGDAR 500MG/50ML INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of IKGDAR 500MG/50ML INJECTIONArrow

  • IKGDAR 500MG/50ML INJECTION must be administered exclusively by a qualified healthcare professional, such as a doctor or nurse, who is trained in its proper use and management of potential side effects. Self-administration is strictly prohibited. Prior to receiving IKGDAR 500MG/50ML INJECTION, you will be given pre-medications to minimize the risk and severity of any adverse reactions. These pre-medications are an essential part of the treatment protocol to ensure your safety and comfort.
  • The dosage and duration of your treatment with IKGDAR 500MG/50ML INJECTION will be determined by your doctor, taking into careful consideration the severity of your condition, your overall health status, and other relevant factors. It is crucial to adhere to your doctor's prescribed dosage and treatment schedule for the best possible outcome.
  • IKGDAR 500MG/50ML INJECTION is administered as an intravenous infusion, meaning it is delivered directly into your vein over a specific period. During the infusion, you will be closely monitored by healthcare professionals for any signs of unwanted side effects. This close monitoring allows for prompt intervention and management of any potential issues, ensuring your safety and well-being throughout the treatment process.

How to store IKGDAR 500MG/50ML INJECTION?Arrow

  • Keep IKGDAR 500MG INJ 50ML away from the reach of children and pets.
  • Store IKGDAR 500MG INJ 50ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of IKGDAR 500MG/50ML INJECTIONArrow

  • IKGDAR 500MG/50ML INJECTION is a specialized medication containing a monoclonal antibody that specifically targets the CD20 antigen found on the surface of B-lymphocytes. These B-lymphocytes are a crucial type of white blood cell. By binding to the CD20 antigen, this medication triggers cell death in Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL), effectively combating these conditions.
  • The mechanism of action involves the binding action of IKGDAR 500MG/50ML INJECTION to B-cells, which subsequently blocks their activation and growth. This interference with B-cell function leads to significant anticancer effects, contributing to the treatment of NHL and CLL. The targeted approach minimizes damage to healthy cells, focusing on the affected B-lymphocytes.
  • In the context of rheumatoid arthritis, IKGDAR 500MG/50ML INJECTION plays a crucial role by inhibiting several key processes. It reduces rheumatoid factor production, interferes with antigen presentation, suppresses T-cell activation, and decreases the production of pro-inflammatory cytokines. These actions collectively help to alleviate the symptoms and progression of rheumatoid arthritis, providing relief to patients suffering from this autoimmune disorder.

How to use IKGDAR 500MG/50ML INJECTIONArrow

  • IKGDAR 500MG/50ML INJECTION should only be administered by a trained doctor or nurse. It is crucial that you do not attempt to self-administer this medication.
  • Prior to receiving IKGDAR 500MG/50ML INJECTION, you will be given pre-medications to help minimize potential side effects. These pre-medications are an important part of the treatment process and are designed to ensure your comfort and safety.
  • The dosage and duration of your treatment with IKGDAR 500MG/50ML INJECTION will be determined by your doctor, taking into account the severity of your condition and other relevant individual factors. It's vital to adhere to the prescribed treatment plan for optimal results.
  • IKGDAR 500MG/50ML INJECTION will be administered as an intravenous infusion, allowing the medication to be delivered directly into your bloodstream. During the infusion, you will be closely monitored for any adverse reactions or unwanted side effects. This monitoring ensures that any issues are promptly addressed and managed.

FAQs

What are the special precautions I should be aware of before starting treatment with IKGDAR 500MG/50ML INJECTION?Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are IKGDAR 500MG/50ML infusion-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering IKGDAR 500MG/50ML INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during IKGDAR 500MG/50ML INJECTION?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the IKGDAR 500MG/50ML INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Is weight gain a side effect of IKGDAR 500MG/50ML INJECTION?Arrow

Weight gain has been reported in patients treated with IKGDAR 500MG/50ML INJECTION for non-hodgkin’s lymphoma.

Does IKGDAR 500MG/50ML INJECTION suppress the immune system?Arrow

Yes, it can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking IKGDAR 500MG/50ML INJECTION because it may cause drug-induced immunosuppression.

Are there any known interactions of IKGDAR 500MG/50ML INJECTION with other drugs?Arrow

NULL interaction of IKGDAR 500MG/50ML INJECTION with other drungs

What precautions should I take while taking IKGDAR 500MG/50ML INJECTION?Arrow

Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently because IKGDAR 500MG/50ML INJECTION may cause drug-induced immunosuppression. Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease. Vaccination with live virus vaccines is not recommended before or during the treatment for patients with rheumatoid arthritis. Inform your healthcare professional if you have any active infection during the treatment.

What molecule/combination is used for making IKGDAR 500MG/50ML INJECTION?Arrow

RITUXIMAB is molecule/combination used for making IKGDAR 500MG/50ML INJECTION.

For which ailments/diseases/conditions is IKGDAR 500MG/50ML INJECTION prescribed?Arrow

IKGDAR 500MG/50ML INJECTION is prescribed for Oncology, Gastroenterology, Rheumatology, Orthopaedics ailments/diseases/conditions.

Can IKGDAR 500MG/50ML INJECTION help with Gastroenterology related issues?Arrow

Yes, IKGDAR 500MG/50ML INJECTION may be used in treating certain Gastroenterology related conditions.

References

Book Icon

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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Ratings & Review

Medicines available at good discounted rates and it really help the pockets of the customer...even they help in getting medicines when you order and give your number ..

Pashupati Nath Pandey

Reviewed on 03-02-2024

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(5/5)

Medkart pharmacy is doing good on saving money of customer and good work on aware to people about generic medicines.

Rinkal Surti

Reviewed on 23-11-2022

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Value for money I got a good discount on medicines

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Reviewed on 04-09-2023

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(5/5)

Good services, rates are competitive!

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Reviewed on 16-01-2024

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(5/5)

Best

Vishva Ukani

Reviewed on 07-01-2024

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(5/5)


Marketer / Manufacturer Details

CIPLA PHARMACEUTICAL COMPANY LIMITED

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India

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MRP

39865

₹31892

20 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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