TORITZ T 500MG/50 ML INJECTION
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TORITZ T 500MG/50 ML INJECTION
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TORITZ T 500MG/50 ML INJECTION

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TORITZ T 500MG/50 ML INJECTION

By TORRENT PHARMACEUTICALS LIMITED

MRP

34637.69

₹12443

64.08 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About TORITZ T 500MG/50 ML INJECTION

  • TORITZ T 500MG/50 ML INJECTION contains rituximab as its active ingredient. It is prescribed for various conditions in adults, either alone or in combination with other medications. These conditions include non-Hodgkin's lymphoma, a cancer affecting B-lymphocytes (a type of white blood cell), and chronic lymphocytic leukemia, another common cancer affecting B-cells. Additionally, it's used in conjunction with methotrexate to treat moderate-to-severe rheumatoid arthritis, an autoimmune disease where the immune system attacks the body's own joints. Other applications include treating granulomatosis with polyangiitis or microscopic polyangiitis, inflammatory conditions of blood vessels primarily affecting the lungs and kidneys in adults and children aged 2 years and older. It also addresses moderate to severe pemphigus vulgaris, an autoimmune disorder causing painful blisters on the skin and mucous membranes of the mouth, throat, nose, and genitals.
  • TORITZ T 500MG/50 ML INJECTION belongs to a class of medications known as anti-CD20 monoclonal antibodies. Before using this injection, it's crucial to inform your doctor if you have any allergies to rituximab or any of the injection's other components, a weakened immune system, or an active, severe infection. Disclose any history of heart disease, heart failure, or breathing problems to your physician prior to starting treatment. If you have a history of hepatitis B infection, inform your doctor, as rituximab can sometimes reactivate the virus, potentially leading to severe complications. It is not recommended to be used during pregnancy and breastfeeding.
  • Common side effects of TORITZ T 500MG/50 ML INJECTION may include blood infections, reduced red blood cell count, dizziness, swelling in the face and body, itchy skin, diarrhea, increased sweating, and fluctuations in blood pressure (either low or high). If you are capable of becoming pregnant, it is essential to use effective contraception during treatment and for 12 months after the last dose. This medication can sometimes cause severe infusion reactions during or within 24 hours of administration. Immediately notify your physician or healthcare professional if you experience any infusion-related reactions such as increased blood pressure, chest pain, headache, breathing difficulties, vomiting, skin rashes, or throat swelling. Regular monitoring and prompt reporting of any unusual symptoms are vital during the treatment with this injection.
  • Furthermore, be aware that rituximab can sometimes cause late-onset neutropenia (low neutrophil count) even several months after the treatment is completed. Your doctor may recommend regular blood tests to monitor your blood cell counts. If you develop any signs of infection, such as fever, chills, cough, or sore throat, even after completing the treatment, consult your doctor immediately. Also, discuss any other medications or supplements you are currently taking with your doctor to avoid potential drug interactions. This comprehensive approach ensures patient safety and optimal treatment outcomes.

Uses of TORITZ T 500MG/50 ML INJECTION

  • Non-Hodgkin's Lymphoma (NHL), a type of cancer that begins in the lymphatic system, affecting white blood cells called lymphocytes. TORITZ T 500MG/50 ML INJECTION is used in certain treatment regimens.
  • Chronic Lymphocytic Leukemia (CLL), a slow-growing type of blood and bone marrow cancer that affects lymphocytes. TORITZ T 500MG/50 ML INJECTION may be part of the treatment plan.
  • Rheumatoid Arthritis, a chronic inflammatory disorder affecting many joints, including those in the hands and feet. TORITZ T 500MG/50 ML INJECTION can be employed to manage symptoms.
  • Granulomatosis with Polyangiitis or Microscopic Polyangiitis, rare autoimmune diseases that cause inflammation of blood vessels. TORITZ T 500MG/50 ML INJECTION is sometimes used in treatment.
  • Pemphigus Vulgaris, a rare autoimmune disorder that causes painful blisters on the skin and mucous membranes. TORITZ T 500MG/50 ML INJECTION is a potential treatment option.

Side Effects of TORITZ T 500MG/50 ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. TORITZ T 500MG/50 ML INJECTION can cause some side effects, though not everyone experiences them.

  • Swelling in the face and body
  • Diarrhea and nausea
  • Itchy skin
  • Anemia
  • Muscle spasm
  • Headache
  • Urinary tract infection
  • Fever, chills, and shivering
  • Inflammation of nasal cavities
  • Cough, sore throat
  • Loss of hair
  • Increased or decreased blood pressure
  • Chest pain
  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Memory loss, trouble thinking, difficulty in walking

Safety Advice for TORITZ T 500MG/50 ML INJECTIONArrow

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Pregnancy

UNSAFE

TORITZ T 500MG/50 ML INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of TORITZ T 500MG/50 ML INJECTIONArrow

  • TORITZ T 500MG/50 ML INJECTION should only be administered by a trained doctor or nurse in a clinical setting. Self-administration is strictly prohibited. Prior to receiving TORITZ T 500MG/50 ML INJECTION, you will be given pre-medications to minimize potential side effects and ensure your comfort during the infusion. The dosage and duration of your treatment will be determined by your doctor, taking into account the severity of your condition, your overall health, and any other medications you may be taking.
  • The injection is administered intravenously as a slow infusion. Throughout the infusion process, you will be closely monitored by healthcare professionals for any adverse reactions or unwanted side effects. It is crucial to inform your doctor or nurse immediately if you experience any unusual symptoms or discomfort during or after the infusion. This close monitoring allows for prompt management of any potential issues and ensures your safety and well-being.
  • Your doctor will individualize the treatment plan based on your specific needs and response to the medication. Regular follow-up appointments are essential to assess the effectiveness of the treatment and make any necessary adjustments. Do not hesitate to ask any questions or voice any concerns you may have regarding your treatment with TORITZ T 500MG/50 ML INJECTION.

How to store TORITZ T 500MG/50 ML INJECTION?Arrow

  • Keep TORITZ T 500MG INJ 50ML away from the reach of children and pets.
  • Store TORITZ T 500MG INJ 50ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of TORITZ T 500MG/50 ML INJECTIONArrow

  • TORITZ T 500MG/50 ML INJECTION is a targeted therapy that zeroes in on CD20, an antigen found on the surface of B-lymphocytes. These B-cells are a type of white blood cell and play a crucial role in certain conditions like Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL).
  • When TORITZ T 500MG/50 ML INJECTION attaches to the B-cell, it triggers a process called cell death. This is particularly important in NHL and CLL, where the uncontrolled growth of B-cells contributes to the disease. By eliminating these cells, the injection helps to manage these conditions.
  • Furthermore, the binding action of TORITZ T 500MG/50 ML INJECTION prevents the activation and growth of B-cells. This inhibitory effect contributes to its anticancer properties. In the context of rheumatoid arthritis, TORITZ T 500MG/50 ML INJECTION also works by inhibiting rheumatoid factor production.
  • Beyond directly targeting B-cells, TORITZ T 500MG/50 ML INJECTION also interferes with antigen presentation, T-cell activation, and the production of pro-inflammatory cytokines. This multi-pronged approach helps to reduce inflammation and manage the symptoms associated with rheumatoid arthritis.

How to use TORITZ T 500MG/50 ML INJECTIONArrow

  • TORITZ T 500MG/50 ML INJECTION should only be administered by a trained healthcare professional, such as a doctor or nurse. It is crucial that you do not attempt to self-administer this medication.
  • Prior to receiving TORITZ T 500MG/50 ML INJECTION, you will be given pre-medications to help minimize potential side effects. These pre-medications are an important part of the treatment process and are designed to improve your overall experience.
  • The dosage and duration of your treatment will be determined by your doctor based on the severity of your condition and other relevant factors. It's important to follow your doctor's instructions precisely.
  • TORITZ T 500MG/50 ML INJECTION will be administered as an intravenous infusion. During the infusion, you will be closely monitored for any adverse reactions or unwanted side effects. This monitoring is essential to ensure your safety and well-being throughout the treatment.
  • If you have any concerns or questions about the administration of TORITZ T 500MG/50 ML INJECTION, please do not hesitate to discuss them with your doctor or nurse. They are there to provide you with the information and support you need.

FAQs

What are the special precautions I should be aware of before starting treatment with TORITZ T 500MG/50 ML INJECTION?Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are TORITZ T 500MG/50 ML INJECTION-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering TORITZ T 500MG/50 ML INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during TORITZ T 500MG/50 ML INJECTION?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the TORITZ T 500MG/50 ML INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Does TORITZ T 500MG/50 ML INJECTION suppress the immune system?Arrow

Yes, can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking TORITZ T 500MG/50 ML INJECTION because it may cause drug-induced immunosuppression.

Is weight gain a side effect of TORITZ T 500MG/50 ML INJECTION?Arrow

Weight gain has been reported in patients treated with TORITZ T 500MG/50 ML INJECTION for non-hodgkin’s lymphoma.

Are there any drug interactions with TORITZ T 500MG/50 ML INJECTION?Arrow

There are no known drug interactions with TORITZ T 500MG/50 ML INJECTION.

What should I avoid while taking TORITZ T 500MG/50 ML INJECTION?Arrow

Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently because TORITZ T 500MG/50 ML INJECTION may cause drug-induced immunosuppression. Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease. Vaccination with live virus vaccines is not recommended before or during the treatment for patients with rheumatoid arthritis. Inform your healthcare professional if you have any active infection during the treatment.

Which molecule/combination is used for making TORITZ T 500MG/50 ML INJECTION?Arrow

RITUXIMAB molecule/combination is used for making TORITZ T 500MG/50 ML INJECTION.

For which ailments/diseases/conditions is TORITZ T 500MG/50 ML INJECTION prescribed?Arrow

TORITZ T 500MG/50 ML INJECTION is prescribed for ailments/diseases/conditions like Oncology, Gastroenterology, Rheumatology, Orthopaedics.

What are the indications for the use of TORITZ T 500MG/50 ML INJECTION?Arrow

TORITZ T 500MG/50 ML INJECTION is used to treat various types of cancers (Oncology), gastrointestinal problems (Gastroenterology), arthritis (Rheumatology), and bone diseases (Orthopaedics).

References

Book Icon

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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Marketer / Manufacturer Details

TORRENT PHARMACEUTICALS LIMITED

Country of Origin -

India

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TORITZ T 500MG/50 ML INJECTION

TORITZ T 500MG/50 ML INJECTION

MRP

34637.69

₹12443

64.08 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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