MABALL 500 INJECTION
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MABALL 500 INJECTION
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MABALL 500 INJECTION

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MABALL 500 INJECTION

By HETERO HEALTHCARE LTD

MRP

35826.5

₹10845

69.73 % OFF

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Composition

Product DetailsArrow

About MABALL 500 INJECTION

  • MABALL 500 INJECTION contains the active ingredient rituximab. It is prescribed for various conditions in adults, either alone or in combination with other medications. It is used to treat non-Hodgkin’s lymphoma, a cancer affecting white blood cells known as B-lymphocytes, and chronic lymphocytic leukemia, a common form of cancer affecting B-cells. Additionally, it is indicated for moderate-to-severe rheumatoid arthritis, a condition where the immune system mistakenly attacks the body's own joints, and is used alongside methotrexate in adults. MABALL 500 INJECTION is also used in the treatment of granulomatosis with polyangiitis or microscopic polyangiitis, inflammatory conditions affecting blood vessels, particularly in the lungs and kidneys, for both adults and children aged 2 years and older. It is also effective against moderate to severe pemphigus vulgaris, an autoimmune disorder causing painful blisters on the skin and the lining of the mouth, throat, nose, and genitals.
  • MABALL 500 INJECTION belongs to a class of medications known as anti-CD20 monoclonal antibodies. It is crucial to avoid this injection if you have a known allergy to rituximab or any of its other ingredients. It is also contraindicated for individuals with a weakened immune system or any severe active infection. Before starting treatment, inform your doctor if you have a history of heart disease, heart failure, or breathing problems. It's important to discuss any previous hepatitis B infection with your doctor, as this infection can reactivate in some cases and may become severe. Pregnancy and breastfeeding are generally not recommended during treatment with this injection.
  • Common side effects associated with MABALL 500 INJECTION include blood infections, reduced red blood cell counts, dizziness, facial and bodily swelling, itchy skin, diarrhea, increased sweating, and fluctuations in blood pressure (either low or high). If you are of childbearing potential, it is essential to use effective contraception during treatment and for 12 months following the last dose. This medication may trigger severe infusion reactions during or within 24 hours of administration. Immediately notify your doctor or healthcare professional if you experience any infusion-related symptoms, such as increased blood pressure, chest pain, headache, breathing difficulties, vomiting, skin rashes, or throat swelling. Regular monitoring and prompt management of any adverse reactions are crucial for patient safety.

Uses of MABALL 500 INJECTION

  • Non-Hodgkin's lymphoma (NHL) is a type of cancer that begins in the lymphatic system. It affects white blood cells and can manifest in various parts of the body. It requires targeted treatment strategies.
  • Chronic lymphocytic leukemia (CLL) is a type of cancer that affects the blood and bone marrow. It is characterized by a gradual increase in lymphocytes, a type of white blood cell. MABALL 500 INJECTION may be considered as part of the treatment approach.
  • Rheumatoid arthritis is a chronic inflammatory disorder affecting many joints, including those in the hands and feet. It's an autoimmune disease where the body's immune system mistakenly attacks its own tissues. MABALL 500 INJECTION can help manage the symptoms and slow the progression of the disease.
  • Granulomatosis with polyangiitis and microscopic polyangiitis are rare autoimmune diseases that cause inflammation of blood vessels. This inflammation can damage organs and tissues throughout the body. MABALL 500 INJECTION is sometimes used to treat these conditions by reducing inflammation.
  • Pemphigus vulgaris is a rare autoimmune disorder that causes painful blisters on the skin and mucous membranes. MABALL 500 INJECTION can be used to suppress the immune system and reduce blister formation, leading to improved skin health.

Side Effects of MABALL 500 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Swelling in the face and body
  • Diarrhea and nausea
  • Itchy skin
  • Anemia
  • Muscle spasm
  • Headache
  • Urinary tract infection
  • Fever, chills, and shivering
  • Inflammation of nasal cavities
  • Cough, sore throat
  • Loss of hair
  • Increased or decreased blood pressure
  • Chest pain
  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Memory loss, trouble thinking, difficulty in walking

Safety Advice for MABALL 500 INJECTIONArrow

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Pregnancy

UNSAFE

MABALL 500 INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of MABALL 500 INJECTIONArrow

  • MABALL 500 INJECTION must be administered exclusively by a qualified doctor or nurse. Self-administration is strictly prohibited. Prior to receiving MABALL 500 INJECTION, you will be given pre-medications to minimize potential side effects. These pre-medications may include antihistamines or corticosteroids, carefully chosen to mitigate possible reactions during the infusion.
  • The dosage and duration of your treatment will be determined by your doctor, taking into account the severity of your condition, your overall health, and other individual factors. This personalized approach ensures that you receive the most effective treatment plan tailored to your specific needs.
  • MABALL 500 INJECTION will be administered as an intravenous infusion, allowing the medication to be delivered directly into your bloodstream. During the infusion, you will be closely monitored for any adverse reactions or unwanted side effects. This vigilant monitoring allows for prompt intervention and management of any potential complications, ensuring your safety and well-being throughout the treatment process.

How to store MABALL 500 INJECTION?Arrow

  • Keep MABALL 500MG INJ 50ML away from the reach of children and pets.
  • Store MABALL 500MG INJ 50ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of MABALL 500 INJECTIONArrow

  • MABALL 500 INJECTION is a specialized medication classified as a monoclonal antibody. It functions by specifically targeting the CD20 antigen, which is prominently displayed on the surface of B-lymphocytes. B-lymphocytes are a crucial type of white blood cell integral to the immune system's response. This targeted approach is particularly beneficial in treating conditions like Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL).
  • Upon administration, MABALL 500 INJECTION binds to the B-cells, triggering a process that leads to cell death. This is a critical mechanism in managing NHL and CLL, as it reduces the number of cancerous B-cells. The binding action of this medicine also plays a role in blocking the activation and growth signals of these cells, effectively hindering their proliferation and contributing to the medicine's anticancer effects.
  • Furthermore, MABALL 500 INJECTION exhibits therapeutic effects in rheumatoid arthritis. It works by inhibiting the production of rheumatoid factor, interfering with antigen presentation, and modulating T-cell activation. Additionally, it reduces the production of pro-inflammatory cytokines, which are key mediators of inflammation in rheumatoid arthritis, thus alleviating the symptoms and progression of the disease.

How to use MABALL 500 INJECTIONArrow

  • MABALL 500 INJECTION must be administered by a trained healthcare professional, such as a doctor or nurse. It is crucial that you do not attempt to self-administer this medication.
  • Prior to receiving MABALL 500 INJECTION, you will be given pre-medications to help minimize potential side effects. These pre-medications are essential for managing your body's response to the infusion.
  • The dosage and duration of your treatment with MABALL 500 INJECTION will be determined by your doctor, taking into account the severity of your condition, your overall health, and other relevant factors. It's important to adhere to the treatment plan prescribed by your doctor.
  • MABALL 500 INJECTION is administered as an intravenous infusion. During the infusion, you will be closely monitored for any adverse reactions or unwanted side effects. This careful monitoring ensures your safety and allows for prompt intervention if needed.
  • Your healthcare provider will adjust the infusion rate as necessary based on your tolerance and response to the medication. Do not hesitate to inform your doctor or nurse if you experience any discomfort or unusual symptoms during the infusion.

FAQs

<strong>What are the special precautions I should be aware of before starting treatment with MABALL 500 INJECTION?</strong>Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are MABALL 500 INJECTION infusion-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering MABALL 500 INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during MABALL 500 INJECTION?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the MABALL 500 INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Is weight gain a side effect of MABALL 500 INJECTION?Arrow

Weight gain has been reported in patients treated with MABALL 500 INJECTION for non-hodgkin’s lymphoma.

Does MABALL 500 INJECTION suppress the immune system?Arrow

Yes, it can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking MABALL 500 INJECTION because it may cause drug-induced immunosuppression.

Is there any interaction of MABALL 500 INJECTION with other drugs?Arrow

NULL interaction of MABALL 500 INJECTION with other drungs

What advice should I follow while taking MABALL 500 INJECTION?Arrow

Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently because MABALL 500 INJECTION may cause drug-induced immunosuppression. Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease. Vaccination with live virus vaccines is not recommended before or during the treatment for patients with rheumatoid arthritis. Inform your healthcare professional if you have any active infection during the treatment.

What molecule/combination is used for making MABALL 500 INJECTION?Arrow

RITUXIMAB is molecule/combination used for making MABALL 500 INJECTION.

For which ailments/diseases/conditions MABALL 500 INJECTION is prescribed?Arrow

MABALL 500 INJECTION is prescribed for ailments/diseases/conditions like Oncology, Gastroenterology, Rheumatology, Orthopaedics.

References

Book Icon

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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Ratings & Review

Best experience Got Discount on medicine

Krushnapalsinh Rathod

Reviewed on 30-11-2023

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(5/5)

(Translated by Google) This is the right medkart for generics. (Original) Generic ke liye ye sahi hai medkart

Pravas Ranjan Acharya

Reviewed on 24-05-2023

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(2/5)

Excellent service

Ali Akhtar

Reviewed on 26-07-2023

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(5/5)

Good for generic medicine, quality medicine with affordable rate

nitesh vekariya

Reviewed on 03-02-2024

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(5/5)

It's a seamless experience.

Mitula Patel

Reviewed on 08-01-2024

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(5/5)


Marketer / Manufacturer Details

HETERO HEALTHCARE LTD

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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