RISTOVA 500MG/50ML INJECTION
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RISTOVA 500MG/50ML INJECTION
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RISTOVA 500MG/50ML INJECTION

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RISTOVA 500MG/50ML INJECTION

By CIPLA PHARMACEUTICAL COMPANY LIMITED

MRP

₹

36004.69

₹32404.22

10 % OFF

10

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Medicine Composition Icon

Composition

RITUXIMAB 500 MG

Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About RISTOVA 500MG/50ML INJECTION

  • RISTOVA 500MG/50ML INJECTION contains the active medicine called rituximab. It is used to treat several serious conditions in adults. It can be used alone or with other medicines to treat a type of cancer affecting white blood cells called B-lymphocytes (Non-Hodgkin's Lymphoma) and a common type of cancer affecting B-cells (Chronic Lymphocytic Leukemia). It is also used to treat moderate to severe rheumatoid arthritis (a condition where the body's immune system attacks its own joints), usually with another medicine called methotrexate. Other uses include treating rare conditions causing blood vessel inflammation, mainly affecting the lungs and kidneys (Granulomatosis with Polyangiitis and Microscopic Polyangiitis) in adults and children aged 2 years and older. It is also used for moderate to severe pemphigus vulgaris (an autoimmune condition causing painful blisters on the skin and inside the mouth, throat, nose, and genitals).
  • RISTOVA 500MG/50ML INJECTION belongs to a group of medicines called 'monoclonal antibodies', specifically targeting a protein called CD20 found on the surface of certain white blood cells (B-cells). By targeting these cells, the medicine helps the body fight the specific diseases it is used for. This can reduce the number of B-cells in the body.
  • You should not receive this injection if you are allergic to rituximab or any other ingredients, have a very weak immune system, or currently have a severe infection.
  • It's crucial to discuss your complete medical history with your doctor before starting treatment with RISTOVA 500MG/50ML INJECTION. Tell your doctor before starting treatment if you have heart problems, heart failure, or breathing difficulties. It's important to inform your doctor if you have ever had Hepatitis B, as this medicine can sometimes cause the virus to become active again, which can be serious. Mention all your health conditions, especially any infections you have now or have had in the past (like Hepatitis B or C, HIV, or shingles), kidney problems, lung problems, or any other serious illness. Also, provide a list of all medications you are currently taking, including prescription, over-the-counter drugs, and herbal supplements, as they can interact with RISTOVA 500MG/50ML INJECTION. This injection is generally not recommended during pregnancy or breastfeeding.
  • Like all medicines, RISTOVA 500MG/50ML INJECTION can cause side effects. Common ones include feeling tired or weak, dizziness, swelling (face/body), itchy skin, diarrhea, increased sweating, and changes in blood pressure (low or high). You might also be more prone to infections. Women who could become pregnant must use effective birth control during treatment and for 12 months after the last dose. RISTOVA 500MG/50ML INJECTION is given as an infusion (drip), and some people may have reactions during or shortly after the infusion (within 24 hours). These can be serious. Tell your doctor or nurse immediately if you notice symptoms like fever, chills, headache, chest pain, breathing problems, swelling (face/throat), or a rash. During your treatment, your doctor will perform regular blood tests to monitor your blood cell counts and check for any signs of infection or other complications. It's important to attend all scheduled appointments and tests.

Uses of RISTOVA 500MG/50ML INJECTION

  • Non-Hodgkin's Lymphoma (NHL): A type of cancer that affects the lymphatic system.
  • Chronic Lymphocytic Leukemia (CLL): A slow-growing type of blood and bone marrow cancer.
  • Rheumatoid Arthritis: An autoimmune disease that causes chronic inflammation of the joints.
  • Granulomatosis with Polyangiitis (GPA) or Microscopic Polyangiitis (MPA): Rare autoimmune diseases that cause inflammation of the blood vessels.
  • Pemphigus Vulgaris: A rare autoimmune disease that causes painful blistering on the skin and mucous membranes.

Side Effects of RISTOVA 500MG/50ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Safety Advice for RISTOVA 500MG/50ML INJECTIONArrow

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Pregnancy

UNSAFE

RISTOVA 500MG/50ML INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of RISTOVA 500MG/50ML INJECTIONArrow

  • RISTOVA 500MG/50ML INJECTION is a powerful medication that must only be given by a healthcare professional, like a doctor or nurse. It is not safe to inject this medicine yourself at home. Before receiving RISTOVA 500MG/50ML INJECTION, your doctor may give you other medicines, called pre-medications. These are important because they help reduce the chances of experiencing side effects from RISTOVA. The exact amount of medicine you receive and how long you will need treatment depends entirely on your specific medical condition, how severe it is, and your overall health. Your doctor will carefully determine the right dose and treatment plan for you. This medicine is given directly into a vein through a drip, which is known as an intravenous infusion. During and after the infusion, medical staff will keep a close eye on you to check for any side effects or reactions, ensuring your safety and comfort throughout the treatment process.

How to store RISTOVA 500MG/50ML INJECTION?Arrow

  • Keep RISTOVA 500MG INJ 50ML away from the reach of children and pets.
  • Store RISTOVA 500MG INJ 50ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of RISTOVA 500MG/50ML INJECTIONArrow

  • Helps treat certain types of blood cancer like Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL) by targeting and removing specific cancer cells.
  • Works by targeting B-cells, which are involved in the disease process, to slow down cancer growth and reduce abnormal cells.
  • Helps manage severe Rheumatoid Arthritis by reducing inflammation and autoimmune activity.
  • Reduces symptoms like joint pain, stiffness, and swelling associated with Rheumatoid Arthritis by calming down the immune response.
  • Targets specific cells (B-cells) involved in both certain blood cancers and severe Rheumatoid Arthritis, offering a focused treatment approach.

How to use RISTOVA 500MG/50ML INJECTIONArrow

  • RISTOVA 500MG/50ML INJECTION is a powerful medicine that must be given by a qualified healthcare professional, such as a doctor or nurse. It is crucial that you *do not* try to inject this medication yourself. Before you receive your dose of RISTOVA 500MG/50ML INJECTION, the doctor will usually give you other medicines. These are called 'pre-medications' and they help to lower the chance of experiencing potential side effects from the RISTOVA 500MG/50ML INJECTION itself. The doctor will carefully determine the right amount (dose) of RISTOVA 500MG/50ML INJECTION for you, as well as how long you will need to receive this treatment. This decision is based on your specific health condition, how severe it is, your overall health, and other important factors. The medication is given into a vein through a drip, which is known as an intravenous infusion. During and after the infusion, the medical staff will keep a close watch on you to check for any unexpected reactions or side effects. They are trained to handle any issues that might arise, ensuring your safety throughout the process. Always follow your doctor's instructions regarding this treatment.

Top Substitutes for RISTOVA 500MG/50ML INJECTION

MedicineManufacturerPack SizeMRPMedkart PriceSavings (%)
MABTAS N 500MG INJ 50MLINTAS PHARMACEUTICALS LIMITED5039992.4735081.62
MABTAS 500MG INJ 50MLINTAS PHARMACEUTICALS LIMITED5039992.76830079.25
MABTAS RA 500MG INJ 50MLINTAS PHARMACEUTICALS LIMITED5039994.95830079.25
ENFIERA 500MG INJ 50MLZYDUS LIFESCIENCES LIMITED5039991.881009974.75
RITUXY 500MG INJ 50MLGLENMARK PHARMACEUTICALS LIMITED5040987.51060574.13
MABALL 500MG INJ 50MLHETERO HEALTHCARE LTD5033587.341084567.71
VELTIRO 500MG INJ 50MLZYDUS LIFESCIENCES LIMITED5040968.751092573.33
RITCEMA 500MG INJ 50MLCELON LABORATORIES LTD50375001100070.67
RIXILTA 500MG INJ 50MLHALSTED PHARMA PVT LTD5044214.451100075.12
LUPIXIMAB 500MG INJ 50MLLUPIN LIMITED5013771.4111017.1220
RITUXIPAN 500MG INJ 50MLMANKIND PHARMA LIMITED5039916.81146471.28
ZESTMAB 500MG INJ 50MLRPG LIFE SCIENCES LIMITED5038037.141191868.67
TORITZ 500MG INJ 50MLTORRENT PHARMACEUTICALS LIMITED5039165.941212069.05
TORITZ RA 500MG INJ 50MLTORRENT PHARMACEUTICALS LIMITED5039903.471244368.82
TORITZ T 500MG INJ 50MLTORRENT PHARMACEUTICALS LIMITED5034637.691244364.08
EMTUX 500MG INJ 50MLEMCURE PHARMACEUTICALS LIMITED5044212.581273471.2
RITULASTA 500MG INJ 50MLPLASMAGEN BIOSCIENCES PVT LTD5014253133626.25
RITUCAD 500MG INJ 50MLCADILA PHARMACEUTICALS PRIVATE LIMITED5035669.031350062.15
VORTUXI 500MG INJ 50MLZYDUS LIFESCIENCES LIMITED5034415.51640252.34
CYTOMAB 500MG INJ 50MLALKEM LABORATORIES LIMITED5039696.821666558.02
XMAB 500MG INJ 50MLRPG LIFE SCIENCES LIMITED5035669.021834248.58
CONIMAB 500MG INJCONCORD BIOTECH LTD1044213.441899957.03
MABTAS T 500MG INJ 50MLINTAS PHARMACEUTICALS LIMITED5035669.032004943.79
REDITUX RA 500MG INJ 50MLDR REDDY'S LABORATORIES LIMITED5040688.322062549.31
RITUXEM 500MG INJ 50MLEMCURE PHARMACEUTICALS LIMITED5039915.272132946.56
RITUXIREL RN 500MG INJ 50MLRELIANCE LIFE SCIENCES5040995.682700034.14
IKGDAR 500MG INJ 50MLCIPLA PHARMACEUTICAL COMPANY LIMITED5037373.4429898.7520
REDITUX 500MG INJ 50MLDR REDDY'S LABORATORIES LIMITED5035668.961300063.55
RITUXIPCA 500MG VIAL 50MLIPCA LABORATORIES LIMITED5040688.4334585.1715

FAQs

What are the special precautions I should be aware of before starting treatment with RISTOVA 500MG/50ML INJECTION?Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are RISTOVA 500MG/50ML INJECTION infusion-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering RISTOVA 500MG/50ML INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during RISTOVA 500MG/50ML INJECTION?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the RISTOVA 500MG/50ML INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Is weight gain a side effect of RISTOVA 500MG/50ML INJECTION?Arrow

Weight gain has been reported in patients treated with RISTOVA 500MG/50ML INJECTION for non-hodgkin’s lymphoma.

Does RISTOVA 500MG/50ML INJECTION suppress the immune system?Arrow

Yes, can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking RISTOVA 500MG/50ML INJECTION because it may cause drug-induced immunosuppression.

What precautions should I take regarding vaccines and other medications while on RISTOVA 500MG/50ML INJECTION?Arrow

Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently as RISTOVA 500MG/50ML INJECTION may cause drug-induced immunosuppression. Vaccination with live virus vaccines is not recommended before or during the treatment, especially for patients with rheumatoid arthritis. Inform your healthcare professional about all medications you are taking.

What symptoms should I report to my doctor while taking RISTOVA 500MG/50ML INJECTION?Arrow

Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. Inform your physician if you have kidney disease, as there is limited safety information for renal failure patients. Also, inform your healthcare professional if you have any active infection during the treatment.

What is the active molecule in RISTOVA 500MG/50ML INJECTION?Arrow

The active molecule in RISTOVA 500MG/50ML INJECTION is RITUXIMAB.

Can RISTOVA 500MG/50ML INJECTION be used for treating cancer?Arrow

Yes, RISTOVA 500MG/50ML INJECTION is used in the treatment of certain types of cancer, particularly those affecting the blood cells (like non-Hodgkin's lymphoma mentioned in Section 1).

Is RISTOVA 500MG/50ML INJECTION used to treat Arthritis?Arrow

Yes, RISTOVA 500MG/50ML INJECTION is used in the treatment of certain types of Arthritis, such as Rheumatoid Arthritis, often when other treatments have not been effective.

Can RISTOVA 500MG/50ML INJECTION be used for Osteoporosis?Arrow

Based on the provided information, RISTOVA 500MG/50ML INJECTION is prescribed for conditions including Anti Cancer, Arthritis, and Osteoporosis.

References

Book Icon

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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Book Icon

ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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Marketer / Manufacturer Details

CIPLA PHARMACEUTICAL COMPANY LIMITED

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