VELTIRO 500 INJECTION
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VELTIRO 500 INJECTION
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VELTIRO 500 INJECTION

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VELTIRO 500 INJECTION

By ZYDUS LIFESCIENCES LIMITED

MRP

40968.75

₹10925

73.33 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About VELTIRO 500 INJECTION

  • VELTIRO 500 INJECTION contains rituximab as its active ingredient. It is prescribed for various conditions in adults, either alone or in conjunction with other medications. These conditions include non-Hodgkin's lymphoma, a cancer affecting B-lymphocytes (a type of white blood cell), and chronic lymphocytic leukemia, another common cancer affecting B-cells. VELTIRO 500 INJECTION is also used in combination with methotrexate to treat moderate-to-severe rheumatoid arthritis, an autoimmune disease where the immune system attacks the body's own joints. Furthermore, it's indicated for treating granulomatosis with polyangiitis or microscopic polyangiitis, inflammatory conditions of blood vessels primarily affecting the lungs and kidneys, in both adults and children aged 2 years and older. It also addresses moderate to severe pemphigus vulgaris, an autoimmune condition leading to painful blisters on the skin and mucous membranes.
  • VELTIRO 500 INJECTION belongs to a class of medications known as anti-CD20 monoclonal antibodies. It's crucial to avoid this injection if you have a known allergy to rituximab or any of its components, if you have a weakened immune system, or if you currently have a severe active infection. Before starting treatment, inform your doctor if you have a history of heart disease, heart failure, or breathing problems. If you have ever had a hepatitis B infection, discuss this with your doctor, as rituximab can reactivate the infection, potentially leading to severe complications. It is not recommended to use VELTIRO 500 INJECTION during pregnancy and breastfeeding.
  • Common side effects associated with VELTIRO 500 INJECTION include blood infections, reduced red blood cell count (anemia), dizziness, swelling in the face and body (edema), itchy skin (pruritus), diarrhea, increased sweating (hyperhidrosis), and fluctuations in blood pressure (either low or high). Women who are able to become pregnant should use effective contraception during treatment and for 12 months after the last dose. This medication can cause severe infusion reactions during or within 24 hours after administration. Immediately notify your doctor or healthcare professional if you experience any infusion-related symptoms such as increased blood pressure, chest pain, headache, difficulty breathing, vomiting, skin rashes, or throat swelling. It's important to promptly manage any adverse reactions to ensure patient safety and the continued effectiveness of the treatment.

Uses of VELTIRO 500 INJECTION

  • Non-Hodgkin's Lymphoma (NHL): A type of cancer that begins in the lymphatic system. VELTIRO 500 INJECTION can assist in managing this condition.
  • Chronic Lymphocytic Leukemia (CLL): A type of blood cancer. VELTIRO 500 INJECTION is useful in the treatment of this condition.
  • Rheumatoid Arthritis: An autoimmune disease affecting the joints. VELTIRO 500 INJECTION may help alleviate the symptoms associated with this condition.
  • Granulomatosis with Polyangiitis or Microscopic Polyangiitis: These are conditions involving inflammation of blood vessels. VELTIRO 500 INJECTION may play a role in managing these diseases.
  • Pemphigus Vulgaris: A rare autoimmune disease causing blisters on the skin and mucous membranes. It can be treated with VELTIRO 500 INJECTION.

Side Effects of VELTIRO 500 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines; however, not everyone experiences them. Common side effects include swelling in the face and body, diarrhea and nausea, itchy skin, anemia, muscle spasm, headache, urinary tract infection, fever, chills, shivering, inflammation of nasal cavities, cough, sore throat, and hair loss. Serious side effects include increased or decreased blood pressure, chest pain, hypersensitivity reactions, hepatitis B viral infection, and memory loss, trouble thinking, and difficulty in walking.

  • Swelling in the face and body
  • Diarrhea and nausea
  • Itchy skin
  • Anemia
  • Muscle spasm
  • Headache
  • Urinary tract infection
  • Fever, chills, and shivering
  • Inflammation of nasal cavities
  • Cough, sore throat
  • Loss of hair
  • Increased or decreased blood pressure
  • Chest pain
  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Memory loss, trouble thinking, difficulty in walking

Safety Advice for VELTIRO 500 INJECTIONArrow

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Pregnancy

UNSAFE

VELTIRO 500 INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of VELTIRO 500 INJECTIONArrow

  • VELTIRO 500 INJECTION must be administered by a trained healthcare professional, such as a doctor or nurse. It is strictly advised against self-administration.
  • Prior to receiving VELTIRO 500 INJECTION, you will be given pre-medications to help minimize potential side effects. These pre-medications are crucial for ensuring your comfort and safety during the infusion process. Your doctor will determine the specific pre-medications required based on your individual needs and medical history.
  • The dosage and duration of your treatment with VELTIRO 500 INJECTION will be determined by your doctor. They will take into account the severity of your condition, your overall health, and other relevant factors to tailor the treatment plan to your specific needs.
  • VELTIRO 500 INJECTION is administered intravenously, meaning it is delivered directly into a vein through an infusion. During the infusion, you will be closely monitored for any adverse reactions or side effects. The healthcare team will be readily available to address any concerns or provide necessary support.
  • It is important to inform your doctor about any existing medical conditions, allergies, or medications you are currently taking before starting treatment with VELTIRO 500 INJECTION. This information will help them make informed decisions about your treatment plan and minimize potential risks.

How to store VELTIRO 500 INJECTION?Arrow

  • Keep VELTIRO 500MG INJ 50ML away from the reach of children and pets.
  • Store VELTIRO 500MG INJ 50ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of VELTIRO 500 INJECTIONArrow

  • VELTIRO 500 INJECTION is a specialized medication classified as a monoclonal antibody. It precisely targets the CD20 antigen, a protein found on the surface of B-lymphocytes. B-lymphocytes are a crucial component of the immune system, acting as a type of white blood cell.
  • In cases of Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL), VELTIRO 500 INJECTION plays a vital role by attaching to the B-cells and triggering cell death. This targeted action helps to reduce the number of cancerous B-cells in the body.
  • The binding of VELTIRO 500 INJECTION to B-cells also has other important effects. It blocks the activation and growth signals that these cells need to proliferate, further contributing to its anticancer properties. By interfering with these signals, the medication helps to slow down the progression of the disease.
  • Furthermore, in conditions like rheumatoid arthritis, VELTIRO 500 INJECTION inhibits several processes that contribute to inflammation and joint damage. These include the production of rheumatoid factor, the presentation of antigens, the activation of T-cells, and the release of pro-inflammatory cytokines. By targeting these specific pathways, VELTIRO 500 INJECTION helps to alleviate the symptoms of rheumatoid arthritis.

How to use VELTIRO 500 INJECTIONArrow

  • VELTIRO 500 INJECTION is a medication that must be administered exclusively by a trained healthcare professional, such as a doctor or nurse. It is crucial to avoid self-administration of this injection to ensure safety and efficacy.
  • Prior to receiving VELTIRO 500 INJECTION, you will be given pre-medications to mitigate potential side effects. These pre-medications are an important part of the treatment protocol and help manage any adverse reactions.
  • The dosage and duration of your treatment with VELTIRO 500 INJECTION will be determined by your doctor, taking into account the severity of your condition and other relevant factors. Your doctor will tailor the treatment plan to your specific needs to achieve the best possible outcome.
  • VELTIRO 500 INJECTION is administered as an intravenous infusion. During the infusion, you will be closely monitored by healthcare professionals to detect and manage any unwanted side effects that may arise. This close monitoring ensures your safety and allows for prompt intervention if needed.
  • It is important to communicate any concerns or changes in your condition to the healthcare provider administering the injection. They are equipped to address any questions or issues you may have during the treatment process.

FAQs

What are the special precautions I should be aware of before starting treatment with VELTIRO 500 INJECTION?Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

Does VELTIRO 500 INJECTION suppress the immune system?Arrow

Yes, can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking VELTIRO 500 INJECTION because it may cause drug-induced immunosuppression.

What are VELTIRO 500 INJECTION infusion-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering VELTIRO 500 INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during VELTIRO 500 INJECTION?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the VELTIRO 500 INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Is weight gain a side effect of VELTIRO 500 INJECTION?Arrow

Weight gain has been reported in patients treated with VELTIRO 500 INJECTION for non-hodgkin’s lymphoma.

Does VELTIRO 500 INJECTION interact with other drugs?Arrow

There is NULL interaction of VELTIRO 500 INJECTION with other drungs

What precautions should I take while using VELTIRO 500 INJECTION?Arrow

Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently because VELTIRO 500 INJECTION may cause drug-induced immunosuppression. Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease. Vaccination with live virus vaccines is not recommended before or during the treatment for patients with rheumatoid arthritis. Inform your healthcare professional if you have any active infection during the treatment.

Which molecule/combination is used for making VELTIRO 500 INJECTION?Arrow

RITUXIMAB is molecule/combination used for making VELTIRO 500 INJECTION.

For which ailments/diseases/conditions is VELTIRO 500 INJECTION prescribed?Arrow

VELTIRO 500 INJECTION is prescribed for ailments/diseases/conditions like Oncology, Gastroenterology, Rheumatology, Orthopaedics.

References

Book Icon

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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Ratings & Review

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Venkataramanamurty Inguva

Reviewed on 15-07-2023

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Good service in all medicines availability and specially in generic medicines. Very cheapest price to buy generic medicines at naroda area. saving money. Thank you medkart

Keyur Patel

Reviewed on 09-01-2024

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(5/5)

Good and cost effective medicines

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Reviewed on 15-02-2024

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(5/5)

Well satisfying products. Generic medicines are way cheaper and of very good quality. Staff is well behaved and knowledgeable.

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Reviewed on 08-09-2023

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(5/5)

Super service

rensom christy

Reviewed on 06-01-2023

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(5/5)


Marketer / Manufacturer Details

ZYDUS LIFESCIENCES LIMITED

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India

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73.33 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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