EMTUX 500MG INJECTION
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EMTUX 500MG INJECTION
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EMTUX 500MG INJECTION

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EMTUX 500MG INJECTION

By EMCURE PHARMACEUTICALS LIMITED

MRP

₹

47160.08

₹12734

73 % OFF

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Composition

RITUXIMAB 500 MG

Product DetailsArrow

About EMTUX 500MG INJECTION

  • EMTUX 500MG INJECTION contains rituximab as its active ingredient. It is prescribed for various conditions in adults, often used alone or in combination with other medications. It's a common treatment for non-Hodgkin’s lymphoma, a cancer affecting B-lymphocytes (a type of white blood cell), and chronic lymphocytic leukemia, another cancer that impacts B-cells. Additionally, it's used, along with methotrexate, to treat moderate-to-severe rheumatoid arthritis, an autoimmune disease where the immune system mistakenly attacks the body's own joint cells. EMTUX 500MG INJECTION is also indicated for treating granulomatosis with polyangiitis or microscopic polyangiitis, both inflammatory conditions of blood vessels primarily affecting the lungs and kidneys, and it can be used in both adults and children ages 2 years and older. It also addresses moderate to severe pemphigus vulgaris, an autoimmune disorder leading to painful blisters on the skin, mouth lining, throat, nose, and genitals.
  • EMTUX 500MG INJECTION belongs to a class of drugs known as anti-CD20 monoclonal antibodies. It's crucial to avoid this injection if you have a known allergy to rituximab or any of its components, if you have a weakened immune system, or if you are currently battling a severe active infection. Before starting treatment, inform your doctor about any pre-existing heart conditions, including heart disease or heart failure, and any breathing difficulties you may experience. Furthermore, disclose if you have a history of hepatitis B infection, as this medication can reactivate the infection in some instances, potentially leading to severe complications. Pregnancy and breastfeeding are generally not recommended while undergoing treatment with this injection. Discuss alternative options with your healthcare provider.
  • Common side effects associated with EMTUX 500MG INJECTION may include blood infections, reduced red blood cell count (anemia), dizziness, swelling in the face and body (edema), itchy skin (pruritus), diarrhea, increased sweating (hyperhidrosis), and fluctuations in blood pressure (either low or high). If you are of childbearing potential, it is essential to use effective contraception methods during the course of treatment and for 12 months following the final dose to prevent pregnancy. This medication can sometimes trigger severe infusion reactions during or within 24 hours after administration. Immediately notify your physician or another healthcare professional if you experience any signs of an infusion reaction, such as elevated blood pressure, chest pain, severe headache, difficulty breathing, vomiting, skin rashes, or swelling of the throat.

Uses of EMTUX 500MG INJECTION

  • Non-Hodgkin's Lymphoma (NHL): EMTUX 500MG INJECTION can be utilized in the treatment of Non-Hodgkin's Lymphoma (NHL), a type of cancer that originates in the lymphatic system. It targets and destroys cancerous cells, contributing to the management of the disease.
  • Chronic Lymphocytic Leukemia (CLL): EMTUX 500MG INJECTION is indicated for use in treating Chronic Lymphocytic Leukemia (CLL), a slow-progressing cancer of the blood and bone marrow. It helps to reduce the number of leukemia cells in the body.
  • Rheumatoid Arthritis: EMTUX 500MG INJECTION can be used in the management of Rheumatoid Arthritis, an autoimmune disorder characterized by inflammation of the joints. It helps in reducing inflammation and alleviating associated symptoms.
  • Granulomatosis with Polyangiitis or Microscopic Polyangiitis: EMTUX 500MG INJECTION is useful in treating Granulomatosis with Polyangiitis and Microscopic Polyangiitis, which are rare autoimmune diseases that affect the blood vessels. It reduces the inflammation and damage caused by these conditions.
  • Pemphigus Vulgaris: EMTUX 500MG INJECTION is used in the treatment of Pemphigus Vulgaris, a rare autoimmune disease that causes blistering of the skin and mucous membranes. It helps to control the immune response and reduce blister formation.

Side Effects of EMTUX 500MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Swelling in the face and body
  • Diarrhea and nausea
  • Itchy skin
  • Anemia
  • Muscle spasm
  • Headache
  • Urinary tract infection
  • Fever, chills, and shivering
  • Inflammation of nasal cavities
  • Cough, sore throat
  • Loss of hair
  • Increased or decreased blood pressure
  • Chest pain
  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Memory loss, trouble thinking, difficulty in walking

Safety Advice for EMTUX 500MG INJECTIONArrow

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Pregnancy

UNSAFE

EMTUX 500MG INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of EMTUX 500MG INJECTIONArrow

  • EMTUX 500MG INJECTION is a medication that must be administered exclusively by a qualified healthcare professional, such as a doctor or nurse, who is trained in its use. Self-administration of this injection is strictly prohibited. Prior to receiving EMTUX 500MG INJECTION, you will be given other medications, referred to as pre-medications, to help minimize the potential for side effects. These pre-medications are an important part of the treatment protocol.
  • The dosage and duration of your treatment with EMTUX 500MG INJECTION will be determined by your doctor, taking into consideration the severity of your condition, your overall health status, and other relevant factors. It is crucial to adhere to your doctor's prescribed dosage and treatment schedule for optimal results.
  • EMTUX 500MG INJECTION will be administered as an intravenous infusion, meaning it will be delivered directly into your vein over a specific period. During the infusion, you will be closely monitored for any adverse reactions or unwanted side effects. This careful monitoring allows for immediate intervention if any issues arise, ensuring your safety and well-being throughout the treatment process.

How to store EMTUX 500MG INJECTION?Arrow

  • Keep EMTUX 500MG INJ 50ML away from the reach of children and pets.
  • Store EMTUX 500MG INJ 50ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of EMTUX 500MG INJECTIONArrow

  • EMTUX 500MG INJECTION is a targeted therapy that zeroes in on CD20, an antigen found on the surface of B-lymphocytes, which are a type of white blood cell. By binding to these B-cells, the injection triggers cell death, making it an effective treatment for Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL). This binding action not only induces cell death but also disrupts the processes that lead to uncontrolled cell growth and proliferation, ultimately contributing to its anticancer effects.
  • In the context of rheumatoid arthritis, EMTUX 500MG INJECTION plays a multifaceted role. It reduces the production of rheumatoid factor, a key indicator of the disease. Furthermore, it interferes with antigen presentation, a process crucial for the activation of T-cells, which are central to the inflammatory response in rheumatoid arthritis. By inhibiting T-cell activation and reducing the production of pro-inflammatory cytokines, EMTUX 500MG INJECTION helps to alleviate the inflammation and joint damage associated with the condition.
  • The precise mechanism of action allows EMTUX 500MG INJECTION to selectively target and eliminate B-cells, which are implicated in the pathogenesis of both NHL/CLL and rheumatoid arthritis. This targeted approach minimizes the impact on other healthy cells in the body, potentially reducing the risk of widespread side effects. Its effectiveness stems from its ability to modulate the immune system by targeting a specific cell type, therefore offering a therapeutic avenue for managing these chronic and debilitating conditions.

How to use EMTUX 500MG INJECTIONArrow

  • EMTUX 500MG INJECTION is a medication that must be administered strictly by a trained healthcare professional, such as a doctor or nurse. It is crucial that you do not attempt to self-administer this injection under any circumstances.
  • Prior to receiving EMTUX 500MG INJECTION, you will be given premedications. These premedications are administered to minimize the potential for side effects and ensure a more comfortable experience during the infusion process. Your doctor will determine the specific premedications required based on your individual needs and medical history.
  • The dosage and duration of your treatment with EMTUX 500MG INJECTION will be determined by your doctor. These factors will be carefully considered based on the severity of your condition, your response to the medication, and any other relevant factors. It's crucial to adhere to your doctor's prescribed dosage and treatment schedule for optimal results.
  • EMTUX 500MG INJECTION will be administered as an intravenous infusion. This means that the medication will be delivered directly into your bloodstream through a vein. During the infusion, you will be closely monitored by healthcare professionals to detect any unwanted side effects or adverse reactions. This monitoring is essential to ensure your safety and well-being throughout the treatment process.

FAQs

What are the special precautions I should be aware of before starting treatment with EMTUX 500MG INJECTION?Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are EMTUX 500MG infusion-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering EMTUX 500MG INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during EMTUX 500MG INJECTION?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the EMTUX 500MG INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Is weight gain a side effect of EMTUX 500MG INJECTION?Arrow

Weight gain has been reported in patients treated with EMTUX 500MG INJECTION for non-hodgkin’s lymphoma.

Does EMTUX 500MG INJECTION suppress the immune system?Arrow

Yes, can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking EMTUX 500MG INJECTION because it may cause drug-induced immunosuppression.

Is there any drug interaction with EMTUX 500MG INJECTION?Arrow

There is NULL interaction of EMTUX 500MG INJECTION with other drugs

What precautions should I take while using EMTUX 500MG INJECTION?Arrow

Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently because EMTUX 500MG INJECTION may cause drug-induced immunosuppression. Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease. Vaccination with live virus vaccines is not recommended before or during the treatment for patients with rheumatoid arthritis. Inform your healthcare professional if you have any active infection during the treatment.

What molecule/combination is used for making EMTUX 500MG INJECTION?Arrow

RITUXIMAB is molecule/combination used for making EMTUX 500MG INJECTION.

For which ailments/diseases/conditions is EMTUX 500MG INJECTION prescribed?Arrow

EMTUX 500MG INJECTION is prescribed for ailments/diseases/conditions related to Oncology, Gastroenterology, Rheumatology, and Orthopaedics.

References

Book Icon

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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