TORITZ 500MG/50ML INJECTION
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TORITZ 500MG/50ML INJECTION
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TORITZ 500MG/50ML INJECTION

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TORITZ 500MG/50ML INJECTION

By TORRENT PHARMACEUTICALS LIMITED

MRP

39165.94

₹12120

69.05 % OFF

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Composition

Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About TORITZ 500MG/50ML INJECTION

  • TORITZ 500MG/50ML INJECTION contains rituximab as its active ingredient. It is prescribed for various conditions in adults, either alone or in combination with other medications. It is used in the treatment of non-Hodgkin's lymphoma, a cancer affecting white blood cells known as B-lymphocytes, and chronic lymphocytic leukemia, a common form of cancer that impacts B-cells. Additionally, it is indicated for treating moderate-to-severe rheumatoid arthritis, a condition where the immune system mistakenly attacks the body's own joint cells, in conjunction with methotrexate. Other applications include the treatment of granulomatosis with polyangiitis or microscopic polyangiitis, which involve inflammation of blood vessels primarily affecting the lungs and kidneys, in both adults and children aged 2 years and older. It is also prescribed for moderate to severe pemphigus vulgaris, an autoimmune disorder causing painful blisters on the skin and the lining of the mouth, throat, nose, and genitals.
  • TORITZ 500MG/50ML INJECTION is classified as an anti-CD20 monoclonal antibody. Avoid using this injection if you have a known allergy to rituximab or any of its components, have a weakened immune system, or are currently experiencing a severe active infection. Before starting treatment, inform your doctor if you have a history of heart disease, heart failure, or breathing difficulties. It's important to discuss any previous hepatitis B infection with your doctor, as reactivation of the infection can occur in some instances and may be severe. Pregnancy and breastfeeding are not recommended while using this injection. Women of childbearing potential should use effective contraception during treatment and for 12 months after the final dose.
  • Common side effects of TORITZ 500MG/50ML INJECTION may include blood infection, reduced red blood cell count, dizziness, facial and body swelling, itchy skin, diarrhea, increased sweating, and fluctuations in blood pressure (either low or high). This medication has the potential to cause severe infusion reactions during or within 24 hours of administration. If you experience any infusion-related symptoms, such as increased blood pressure, chest pain, headache, breathing difficulties, vomiting, skin rashes, or throat swelling, immediately notify your physician or healthcare provider. Regular monitoring and prompt communication with your healthcare team are crucial for managing potential side effects and ensuring safe and effective treatment. Patients should be aware of the possible risks and benefits before initiating therapy with TORITZ 500MG/50ML INJECTION, and any concerns should be discussed with their healthcare provider.

Uses of TORITZ 500MG/50ML INJECTION

  • Non-Hodgkin's Lymphoma (NHL): A type of cancer that begins in the lymphatic system, where lymphocytes grow abnormally and can form tumors throughout the body.
  • Chronic Lymphocytic Leukemia (CLL): A slow-growing type of blood cancer in which the bone marrow makes too many lymphocytes.
  • Rheumatoid Arthritis: An autoimmune and inflammatory disease, which means that your immune system attacks healthy cells in your body, causing inflammation (painful swelling) in the affected parts of the body.
  • Granulomatosis with Polyangiitis or Microscopic Polyangiitis: Rare autoimmune diseases that cause inflammation of the blood vessels. TORITZ 500MG/50ML INJECTION may be used in the treatment.
  • Pemphigus Vulgaris: A rare autoimmune disease that causes painful blisters on the skin and mucous membranes. TORITZ 500MG/50ML INJECTION may be used in the treatment.

Side Effects of TORITZ 500MG/50ML INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. TORITZ 500MG/50ML INJECTION can cause side effects.

  • Swelling in the face and body
  • Diarrhea and nausea
  • Itchy skin
  • Anemia
  • Muscle spasm
  • Headache
  • Urinary tract infection
  • Fever, chills, and shivering
  • Inflammation of nasal cavities
  • Cough, sore throat
  • Loss of hair
  • Increased or decreased blood pressure
  • Chest pain
  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Memory loss, trouble thinking, difficulty in walking

Safety Advice for TORITZ 500MG/50ML INJECTIONArrow

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Pregnancy

UNSAFE

TORITZ 500MG/50ML INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of TORITZ 500MG/50ML INJECTIONArrow

  • TORITZ 500MG/50ML INJECTION must be administered exclusively by a qualified healthcare professional, such as a trained doctor or nurse. Self-administration is strictly prohibited. Prior to receiving TORITZ 500MG/50ML INJECTION, you will be administered pre-medications to mitigate potential side effects. These pre-medications are crucial for ensuring your comfort and safety during the infusion process. Your doctor will determine the appropriate dosage and duration of your treatment, taking into account the severity of your condition, your overall health status, and other relevant factors. This personalized approach ensures that you receive the most effective treatment with minimal risk.
  • TORITZ 500MG/50ML INJECTION is administered intravenously, meaning it is delivered directly into your vein via an infusion. During the infusion, you will be under close observation by medical personnel who will monitor you carefully for any adverse reactions or unwanted side effects. This continuous monitoring allows for immediate intervention if any issues arise, ensuring your well-being throughout the procedure. It's essential to inform your doctor about any existing medical conditions, allergies, or medications you are currently taking to ensure the safe and effective administration of TORITZ 500MG/50ML INJECTION.

How to store TORITZ 500MG/50ML INJECTION?Arrow

  • Keep TORITZ 500MG INJ 50ML away from the reach of children and pets.
  • Store TORITZ 500MG INJ 50ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of TORITZ 500MG/50ML INJECTIONArrow

  • TORITZ 500MG/50ML INJECTION is a specialized medication classified as a monoclonal antibody, meticulously designed to target the CD20 antigen present on the surface of B-lymphocytes. B-lymphocytes are a crucial type of white blood cell integral to the immune system. This targeted action is particularly beneficial in conditions like Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL).
  • Upon administration, TORITZ 500MG/50ML INJECTION binds specifically to the CD20 antigen on B-cells. This binding triggers a cascade of events that ultimately lead to the programmed death, or apoptosis, of these targeted cells. This mechanism is vital in reducing the population of cancerous B-cells in NHL and CLL, contributing to disease remission and improved patient outcomes.
  • Beyond its direct cytotoxic effect on B-cells, TORITZ 500MG/50ML INJECTION also disrupts key B-cell functions. By blocking cell activation and growth signals, it effectively halts the uncontrolled proliferation characteristic of lymphomas and leukemias. This inhibitory action further enhances its anticancer effects, preventing the disease from progressing.
  • In the context of rheumatoid arthritis, TORITZ 500MG/50ML INJECTION plays a multifaceted role in modulating the immune response. It inhibits the production of rheumatoid factor, a hallmark antibody associated with the disease. Additionally, it interferes with antigen presentation, a critical step in T-cell activation, and reduces the production of proinflammatory cytokines, thus alleviating the inflammatory cascade that drives joint damage and pain in rheumatoid arthritis.
  • Through these combined mechanisms, TORITZ 500MG/50ML INJECTION offers a comprehensive therapeutic approach for managing B-cell malignancies and autoimmune disorders like rheumatoid arthritis, providing significant benefits for patients suffering from these conditions.

How to use TORITZ 500MG/50ML INJECTIONArrow

  • TORITZ 500MG/50ML INJECTION must be administered strictly by a trained doctor or nurse. Self-administration is not advised under any circumstances. Prior to receiving TORITZ 500MG/50ML INJECTION, you will be given pre-medications to minimize potential side effects. These pre-medications are crucial in ensuring your comfort and safety during the infusion.
  • The dosage and duration of your treatment will be determined by your doctor, taking into account the severity of your condition and other relevant factors. This personalized approach ensures that you receive the most effective treatment plan tailored to your specific needs. The doctor will consider your overall health and response to the medication when adjusting the dosage.
  • TORITZ 500MG/50ML INJECTION is administered intravenously as an infusion. During the infusion, you will be closely monitored for any adverse reactions or side effects. This continuous monitoring allows the healthcare team to promptly address any concerns and ensure your well-being throughout the process. Regular checks of vital signs will be conducted to maintain optimal safety.

FAQs

What are the special precautions I should be aware of before starting treatment with TORITZ 500MG/50ML INJECTION?Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are TORITZ 500MG/50ML INFUSION-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering TORITZ 500MG/50ML INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during TORITZ 500MG/50ML INJECTION?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the TORITZ 500MG/50ML INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Is weight gain a side effect of TORITZ 500MG/50ML INJECTION?Arrow

Weight gain has been reported in patients treated with TORITZ 500MG/50ML INJECTION for non-hodgkin’s lymphoma.

Does TORITZ 500MG/50ML INJECTION suppress the immune system?Arrow

Yes, can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking TORITZ 500MG/50ML INJECTION because it may cause drug-induced immunosuppression.

Are there any known interactions of TORITZ 500MG/50ML INJECTION with other drugs?Arrow

NULL interaction of TORITZ 500MG/50ML INJECTION with other drungs

What are some advices related to TORITZ 500MG/50ML INJECTION?Arrow

Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently because TORITZ 500MG/50ML INJECTION may cause drug-induced immunosuppression. Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease. Vaccination with live virus vaccines is not recommended before or during the treatment for patients with rheumatoid arthritis. Inform your healthcare professional if you have any active infection during the treatment.

Which molecule/combination is used for making TORITZ 500MG/50ML INJECTION?Arrow

RITUXIMAB is molecule/combination used for making TORITZ 500MG/50ML INJECTION.

For which ailments/diseases/conditions is TORITZ 500MG/50ML INJECTION prescribed?Arrow

TORITZ 500MG/50ML INJECTION is prescribed for ailments/diseases/conditions such as Oncology, Gastroenterology, Rheumatology, and Orthopaedics.

References

Book Icon

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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Ratings & Review

Good service and discount. Help me to get a good discount on some of my daily meds

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Reviewed on 05-08-2023

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The customer care was ans the response to customer was fabulo

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Marketer / Manufacturer Details

TORRENT PHARMACEUTICALS LIMITED

Country of Origin -

India

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TORITZ 500MG/50ML INJECTION

TORITZ 500MG/50ML INJECTION

MRP

39165.94

₹12120

69.05 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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