CYTOMAB 500MG INJECTION 50 ML
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CYTOMAB 500MG INJECTION 50 ML
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CYTOMAB 500MG INJECTION 50 ML

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CYTOMAB 500MG INJECTION 50 ML

By ALKEM LABORATORIES LIMITED

MRP

42343.27

₹16665

60.64 % OFF

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Composition

Product DetailsArrow

About CYTOMAB 500MG INJECTION 50 ML

  • CYTOMAB 500MG INJECTION 50 ML contains rituximab as its active ingredient. It is prescribed for various conditions in adults, either alone or in conjunction with other medications. Primarily, it is used in the treatment of non-Hodgkin's lymphoma, a cancer affecting B-lymphocytes (a type of white blood cell), and chronic lymphocytic leukemia, a common form of cancer that also impacts B-cells. Additionally, it is indicated for moderate-to-severe rheumatoid arthritis, an autoimmune disease where the immune system mistakenly attacks the body's own joints, and is used alongside methotrexate for this purpose. Furthermore, CYTOMAB 500MG INJECTION 50 ML is used in treating granulomatosis with polyangiitis or microscopic polyangiitis, both conditions characterized by inflammation of blood vessels, predominantly affecting the lungs and kidneys, in both adults and children aged two years and older. It is also employed in managing moderate to severe pemphigus vulgaris, an autoimmune disorder causing painful blisters on the skin and the lining of the mouth, throat, nose, and genitals.
  • CYTOMAB 500MG INJECTION 50 ML belongs to a class of drugs known as anti-CD20 monoclonal antibodies. Before using this injection, it is crucial to inform your physician if you have any allergies to rituximab or any of the injection's other components. It's also important to disclose if you have a weak immune system or any severe active infection. Patients with pre-existing heart conditions, heart failure, or breathing problems should inform their doctor before commencing treatment. It is vital to discuss any history of hepatitis B infection with your doctor, as the infection may reactivate in some instances and can be severe. The use of this injection is generally not recommended during pregnancy and breastfeeding.
  • Common side effects associated with CYTOMAB 500MG INJECTION 50 ML include blood infections, reduced red blood cell count, dizziness, swelling of the face and body, itchy skin, diarrhea, increased sweating, and fluctuations in blood pressure (either low or high). If you are a woman of childbearing potential, it is essential to use effective contraceptive methods during treatment and for 12 months following the last dose. This medication has the potential to cause severe infusion reactions during or within 24 hours after administration. Therefore, it is important to promptly notify your physician or healthcare professional if you experience any infusion-related symptoms, such as increased blood pressure, chest pain, headache, breathing difficulties, vomiting, skin rashes, or throat swelling. Regular monitoring and communication with your healthcare provider are crucial throughout the treatment period to manage potential side effects and ensure the medication's effectiveness. While on this medication, avoid live vaccines. Let your doctor know about any other medications you are currently taking.

Uses of CYTOMAB 500MG INJECTION 50 ML

  • Non-Hodgkin's Lymphoma (NHL), a type of cancer that begins in the lymphatic system, needs careful medical attention and CYTOMAB 500MG INJECTION 50 ML could be part of the treatment.
  • Chronic Lymphocytic Leukemia (CLL), another form of cancer affecting the blood and bone marrow, may require specific treatment plans where CYTOMAB 500MG INJECTION 50 ML may play a role.
  • Rheumatoid Arthritis, an autoimmune disorder causing inflammation in the joints, might be managed with various medications, and CYTOMAB 500MG INJECTION 50 ML could be one of them depending on the case's severity.
  • Granulomatosis with Polyangiitis or Microscopic Polyangiitis, rare autoimmune diseases that cause inflammation of blood vessels, necessitates targeted treatments which could include CYTOMAB 500MG INJECTION 50 ML.
  • Pemphigus Vulgaris, a rare autoimmune disease causing blisters on the skin and mucous membranes, often requires immunosuppressive therapies, and CYTOMAB 500MG INJECTION 50 ML may be considered as part of the treatment regimen.

Side Effects of CYTOMAB 500MG INJECTION 50 MLArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. With CYTOMAB 500MG INJECTION 50 ML, some common side effects include swelling in the face and body.

  • Swelling in the face and body
  • Diarrhea and nausea
  • Itchy skin
  • Anemia
  • Muscle spasm
  • Headache
  • Urinary tract infection
  • Fever, chills, and shivering
  • Inflammation of nasal cavities
  • Cough, sore throat
  • Loss of hair
  • Increased or decreased blood pressure
  • Chest pain
  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Memory loss, trouble thinking, difficulty in walking

Safety Advice for CYTOMAB 500MG INJECTION 50 MLArrow

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Pregnancy

UNSAFE

CYTOMAB 500MG INJECTION 50 ML is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of CYTOMAB 500MG INJECTION 50 MLArrow

  • CYTOMAB 500MG INJECTION 50 ML should only be administered by a trained doctor or nurse in a controlled medical setting. Self-administration of this injection is strictly prohibited due to the potential for severe adverse reactions. Prior to receiving CYTOMAB 500MG INJECTION 50 ML, you will be given premedications, such as antihistamines and corticosteroids, to minimize the risk and severity of possible side effects. These premedications help to prepare your body for the infusion.
  • The dosage and duration of your treatment will be determined by your doctor based on several factors, including the severity and type of your condition, your overall health, and your response to the medication. It's crucial to adhere to the prescribed dosage schedule. CYTOMAB 500MG INJECTION 50 ML is administered as an intravenous infusion, allowing the medication to be delivered directly into your bloodstream. During the infusion, you will be closely monitored by healthcare professionals for any signs of adverse reactions or complications.
  • Regular monitoring is essential to ensure your safety and the effectiveness of the treatment. Report any unusual or concerning symptoms to your doctor or nurse immediately. They are equipped to manage any potential side effects that may arise during or after the infusion. Do not hesitate to communicate any discomfort or concerns you may have throughout the treatment process.

How to store CYTOMAB 500MG INJECTION 50 ML?Arrow

  • Keep CYTOMAB 500MG INJ 50ML away from the reach of children and pets.
  • Store CYTOMAB 500MG INJ 50ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of CYTOMAB 500MG INJECTION 50 MLArrow

  • CYTOMAB 500MG INJECTION 50 ML is a specialized medication classified as a monoclonal antibody. It functions by specifically targeting the CD20 antigen, which is found on the surface of B-lymphocytes, a specific type of white blood cell. These B-lymphocytes are often implicated in conditions like Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL).
  • When CYTOMAB 500MG INJECTION 50 ML attaches to these B-cells, it triggers a process of cell death, effectively reducing the number of these problematic cells in NHL and CLL. This targeted binding action also plays a crucial role in preventing the activation and subsequent growth of these cells, thereby exerting anticancer effects. By blocking these processes, the medication helps to control the progression of these conditions.
  • In the context of rheumatoid arthritis, CYTOMAB 500MG INJECTION 50 ML works by inhibiting several key factors involved in the disease's progression. This includes reducing the production of rheumatoid factor, hindering antigen presentation, suppressing T-cell activation, and decreasing the production of pro-inflammatory cytokines. These actions collectively contribute to reducing inflammation and alleviating the symptoms associated with rheumatoid arthritis.

How to use CYTOMAB 500MG INJECTION 50 MLArrow

  • CYTOMAB 500MG INJECTION 50 ML is a medication that should only be administered by a qualified healthcare professional, such as a trained doctor or nurse. It is crucial that you do not attempt to self-administer this injection under any circumstances.
  • Prior to receiving CYTOMAB 500MG INJECTION 50 ML, you will be given other medications, often referred to as pre-medication. These pre-medications are designed to help minimize the potential side effects that may occur during or after the infusion. Your doctor will carefully select these medications based on your individual needs and medical history.
  • The dosage and duration of your treatment with CYTOMAB 500MG INJECTION 50 ML will be determined by your doctor. They will take into account the severity of your condition, your overall health, and other relevant factors to ensure that you receive the most appropriate and effective treatment plan. It's important to adhere to the prescribed dosage and schedule.
  • CYTOMAB 500MG INJECTION 50 ML is administered intravenously, meaning it is given directly into a vein through an infusion. During the infusion process, you will be closely monitored by healthcare professionals to detect any unwanted side effects or adverse reactions. This close monitoring allows for prompt intervention if any issues arise, ensuring your safety and well-being.

FAQs

What are the special precautions I should be aware of before starting treatment with CYTOMAB 500MG INJECTION 50 ML?Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are CYTOMAB 500MG INJECTION 50 ML infusion-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering CYTOMAB 500MG INJECTION 50 ML. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during CYTOMAB 500MG INJECTION 50 ML?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the CYTOMAB 500MG INJECTION 50 ML. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Is weight gain a side effect of CYTOMAB 500MG INJECTION 50 ML?Arrow

Weight gain has been reported in patients treated with CYTOMAB 500MG INJECTION 50 ML for non-hodgkin’s lymphoma.

Does CYTOMAB 500MG INJECTION 50 ML suppress the immune system?Arrow

Yes, it can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking CYTOMAB 500MG INJECTION 50 ML because it may cause drug-induced immunosuppression.

NULL interaction of CYTOMAB 500MG INJECTION 50 ML with other drungsArrow

There are no known interactions of CYTOMAB 500MG INJECTION 50 ML with other drugs.

What is the advice related to CYTOMAB 500MG INJECTION 50 ML?Arrow

Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently because CYTOMAB 500MG INJECTION 50 ML may cause drug-induced immunosuppression. Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease. Vaccination with live virus vaccines is not recommended before or during the treatment for patients with rheumatoid arthritis. Inform your healthcare professional if you have any active infection during the treatment.

Which molecule/combination is used for making CYTOMAB 500MG INJECTION 50 ML?Arrow

RITUXIMAB is molecule/combination used for making CYTOMAB 500MG INJECTION 50 ML.

For which ailments/diseases/conditions is CYTOMAB 500MG INJECTION 50 ML prescribed?Arrow

CYTOMAB 500MG INJECTION 50 ML is prescribed for ailments/diseases/conditions such as Oncology, Gastroenterology, Rheumatology, Orthopaedics.

References

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HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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Marketer / Manufacturer Details

ALKEM LABORATORIES LIMITED

Country of Origin -

India

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CYTOMAB 500MG INJECTION 50 ML

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₹16665

60.64 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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