ZESTMAB 500MG INJECTION
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ZESTMAB 500MG INJECTION
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ZESTMAB 500MG INJECTION

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ZESTMAB 500MG INJECTION

By RPG LIFE SCIENCES LIMITED

MRP

38037.14

₹11918

68.67 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About ZESTMAB 500MG INJECTION

  • ZESTMAB 500MG INJECTION contains rituximab as its active ingredient. It is prescribed for the management of several disease conditions in adults. It is administered either as a standalone treatment or alongside other medications for conditions such as non-Hodgkin’s lymphoma (a cancer affecting B-lymphocytes, a type of white blood cell) and chronic lymphocytic leukemia (a common form of cancer affecting B-cells).
  • ZESTMAB 500MG INJECTION is also indicated, in conjunction with methotrexate, for the treatment of moderate-to-severe rheumatoid arthritis (an autoimmune disease where the immune system attacks the body's own joint cells) in adults. Additional uses include the treatment of granulomatosis with polyangiitis or microscopic polyangiitis (inflammatory conditions affecting blood vessels, particularly in the lungs and kidneys) for both adults and children aged 2 years and older. It is further utilized in treating moderate to severe pemphigus vulgaris (an autoimmune disorder characterized by painful blisters on the skin and mucous membranes of the mouth, throat, nose, and genitals).
  • ZESTMAB 500MG INJECTION falls under the category of anti-CD20 monoclonal antibodies. It is crucial to avoid this injection if you have a known allergy to rituximab or any other components of the formulation, if you have a compromised immune system, or if you are currently experiencing a severe active infection. Prior to commencing treatment, inform your healthcare provider about any pre-existing heart conditions, heart failure, or respiratory issues. It is also important to disclose any history of hepatitis B infection, as rituximab can potentially reactivate the virus, leading to severe complications. The use of ZESTMAB 500MG INJECTION during pregnancy and breastfeeding is generally discouraged.
  • Common side effects associated with ZESTMAB 500MG INJECTION may include blood infections, reduced red blood cell count, dizziness, facial and bodily swelling, itchy skin, diarrhea, increased perspiration, and fluctuations in blood pressure (both low and high). Women of childbearing potential should employ effective contraceptive measures during treatment and for a period of 12 months following the final dose. This medication carries a risk of inducing severe infusion reactions during or within 24 hours of administration. Immediately notify your physician or a healthcare professional if you experience any infusion-related symptoms, such as elevated blood pressure, chest discomfort, headache, difficulty breathing, vomiting, skin eruptions, or swelling of the throat.
  • Beyond its primary applications, ZESTMAB 500MG INJECTION is sometimes considered for other autoimmune disorders or conditions involving B-cell dysfunction, under the guidance of a specialist. The exact dosage and treatment schedule will be determined by your doctor based on your specific condition, overall health, and response to the medication. Regular monitoring and follow-up appointments are crucial to assess the effectiveness of the treatment and to manage any potential side effects.
  • It's important to maintain open communication with your healthcare team throughout your treatment with ZESTMAB 500MG INJECTION. Report any new or worsening symptoms promptly. Lifestyle adjustments, such as maintaining a healthy diet and getting adequate rest, can also play a supportive role during your treatment journey.

Uses of ZESTMAB 500MG INJECTION

  • Non-Hodgkin's Lymphoma (NHL): This refers to a group of blood cancers that develop from lymphocytes, a type of white blood cell. Unlike Hodgkin's lymphoma, NHL includes a variety of lymphoma subtypes.
  • Chronic Lymphocytic Leukemia (CLL): A type of cancer in which the bone marrow makes too many lymphocytes. CLL is a slow-growing leukemia.
  • Rheumatoid Arthritis: An autoimmune and inflammatory disease, which means that your immune system attacks healthy cells in your body by mistake, causing inflammation (painful swelling) in the affected parts of the body.
  • Granulomatosis with Polyangiitis or Microscopic Polyangiitis: These are rare autoimmune diseases that cause inflammation of blood vessels. This inflammation can damage organs.
  • Pemphigus Vulgaris: A rare autoimmune disease that causes painful blisters on the skin and mucous membranes.

Side Effects of ZESTMAB 500MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Swelling in the face and body
  • Diarrhea and nausea
  • Itchy skin
  • Anemia
  • Muscle spasm
  • Headache
  • Urinary tract infection
  • Fever, chills, and shivering
  • Inflammation of nasal cavities
  • Cough, sore throat
  • Loss of hair
  • Increased or decreased blood pressure
  • Chest pain
  • Hypersensitivity reactions
  • Hepatitis B viral infection
  • Memory loss, trouble thinking, difficulty in walking

Safety Advice for ZESTMAB 500MG INJECTIONArrow

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Pregnancy

UNSAFE

ZESTMAB 500MG INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of ZESTMAB 500MG INJECTIONArrow

  • ZESTMAB 500MG INJECTION is a specialized medication that must be administered strictly under the supervision of a qualified healthcare professional, such as a trained doctor or nurse. Self-administration is strictly prohibited to ensure patient safety and efficacy of the treatment.
  • Prior to receiving ZESTMAB 500MG INJECTION, you will be administered pre-medications. These pre-medications are crucial in minimizing the potential for side effects associated with the infusion. Your healthcare provider will carefully select these medications based on your individual needs and medical history.
  • The dosage and duration of ZESTMAB 500MG INJECTION treatment will be determined by your doctor, taking into account the severity of your condition, your overall health status, and other relevant factors. It's essential to adhere to the prescribed dosage and treatment schedule for optimal results.
  • ZESTMAB 500MG INJECTION will be administered intravenously, meaning it will be delivered directly into your bloodstream through a vein. During the infusion process, you will be closely monitored by medical personnel for any adverse reactions or unexpected side effects. This close monitoring ensures that any potential issues are promptly addressed.
  • It is essential to inform your doctor about all your current medications and any pre-existing medical conditions before starting ZESTMAB 500MG INJECTION treatment.

How to store ZESTMAB 500MG INJECTION?Arrow

  • Keep ZESTMAB 500MG INJ 50ML away from the reach of children and pets.
  • Store ZESTMAB 500MG INJ 50ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of ZESTMAB 500MG INJECTIONArrow

  • ZESTMAB 500MG INJECTION is a specialized medication classified as a monoclonal antibody. It's designed to precisely target the CD20 antigen, a protein found on the surface of B-lymphocytes. These B-lymphocytes are a specific type of white blood cell, and this medication's action is pivotal in treating certain conditions.
  • In Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL), ZESTMAB 500MG INJECTION works by attaching itself to the B-cells. This binding action triggers a process that leads to the death of these cells, which is crucial in managing these conditions. Furthermore, the medication inhibits B-cell activation and growth, ultimately contributing to its anticancer effects.
  • Beyond its role in cancer treatment, ZESTMAB 500MG INJECTION also plays a significant role in rheumatoid arthritis. It reduces the production of rheumatoid factor, interferes with antigen presentation, and inhibits T-cell activation. Moreover, it suppresses the production of pro-inflammatory cytokines, all of which contribute to the reduction of inflammation and disease activity in rheumatoid arthritis.

How to use ZESTMAB 500MG INJECTIONArrow

  • ZESTMAB 500MG INJECTION should only be administered by a trained doctor or nurse. It is crucial that you do not attempt to self-administer this medication. Prior to receiving ZESTMAB 500MG INJECTION, you will be given pre-medications to help minimize potential side effects. These pre-medications are essential for ensuring your comfort and safety during the infusion process.
  • Your doctor will determine the appropriate dose and duration of your treatment with ZESTMAB 500MG INJECTION. This decision will be based on the severity of your condition, your overall health, and other relevant factors. It is important to follow your doctor's instructions precisely to achieve the best possible outcome.
  • ZESTMAB 500MG INJECTION will be administered as an intravenous infusion. This means that the medication will be delivered directly into your bloodstream through a vein. During the infusion, you will be closely monitored by healthcare professionals for any signs of adverse reactions or unwanted side effects. This careful monitoring is essential for promptly addressing any issues that may arise and ensuring your well-being.

FAQs

What are the special precautions I should be aware of before starting treatment with ZESTMAB 500MG INJECTION?Arrow

Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are ZESTMAB 500MG infusion-related reactions?Arrow

Infusion reactions occur during or within 24 hours after administering ZESTMAB 500MG INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during ZESTMAB 500MG INJECTION?Arrow

Your healthcare professional will monitor you carefully for unwanted side effects during the ZESTMAB 500MG INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Is weight gain a side effect of ZESTMAB 500MG INJECTION?Arrow

Weight gain has been reported in patients treated with ZESTMAB 500MG INJECTION for non-hodgkin’s lymphoma.

Does ZESTMAB 500MG INJECTION suppress the immune system?Arrow

Yes, can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking ZESTMAB 500MG INJECTION because it may cause drug-induced immunosuppression.

Can I take other medications with ZESTMAB 500MG INJECTION?Arrow

NULL interaction of ZESTMAB 500MG INJECTION with other drungs

What advice should I take while taking ZESTMAB 500MG INJECTION?Arrow

Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently because ZESTMAB 500MG INJECTION may cause drug-induced immunosuppression. Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease. Vaccination with live virus vaccines is not recommended before or during the treatment for patients with rheumatoid arthritis. Inform your healthcare professional if you have any active infection during the treatment.

What molecule/combination is used for making ZESTMAB 500MG INJECTION?Arrow

RITUXIMAB is molecule/combination used for making ZESTMAB 500MG INJECTION.

For which ailments/diseases/conditions is ZESTMAB 500MG INJECTION prescribed?Arrow

ZESTMAB 500MG INJECTION is used for treating ailments related to Oncology, Gastroenterology, Rheumatology, Orthopaedics.

Does ZESTMAB 500MG INJECTION help in treating Rheumatoid Arthritis?Arrow

ZESTMAB 500MG INJECTION may help in treating Rheumatoid Arthritis, as it is related to Rheumatology.

References

Book Icon

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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Ratings & Review

Geniune medicines available at good discounts

Vaishali Parikh

Reviewed on 05-12-2022

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(5/5)

Well satisfying products. Generic medicines are way cheaper and of very good quality. Staff is well behaved and knowledgeable.

khozema kaukawala

Reviewed on 08-09-2023

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(5/5)

Gotri Medkart Pharmacy providing generic medicines & other products with affordable price with better service.

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Reviewed on 11-01-2024

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Good service , great discount, I am regular customer

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Reviewed on 27-07-2023

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(5/5)

Quick service, getting discounts on medicines on regular basis

Harshit Patel

Reviewed on 12-02-2024

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(5/5)


Marketer / Manufacturer Details

RPG LIFE SCIENCES LIMITED

Country of Origin -

India

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ZESTMAB 500MG INJECTION

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₹11918

68.67 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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