GLISEN MF 2MG TABLET 15'S with Glimepiride 2 MG + Metformin 500 MG
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GLISEN MF 2MG TABLET 15'S

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GLISEN MF 2MG TABLET 15'S

By ALEMBIC PHARMACEUTICALS LIMITED

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280.15

₹238.13

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About GLISEN MF 2MG TABLET 15'S

  • GLISEN MF 2MG TABLET 15'S is a combination medicine used to treat type 2 diabetes mellitus. It is prescribed for adults when diet and exercise alone are not enough to control blood sugar levels. This medication helps lower blood sugar by increasing insulin secretion by the pancreas and improving the body's response to insulin. It also works by decreasing glucose production in the liver and slowing down the absorption of glucose from the intestines.
  • The 'MF' in GLISEN MF stands for Metformin, a biguanide, which reduces glucose production in the liver and enhances insulin sensitivity in the body's tissues. The 'GLISEN' component typically refers to a sulfonylurea, such as Glimepiride, which stimulates the pancreas to release more insulin. By combining these two medications, GLISEN MF offers a dual-pronged approach to managing blood sugar levels effectively.
  • This medication is usually taken once or twice daily with meals to minimize gastrointestinal side effects. It's crucial to take GLISEN MF exactly as prescribed by your doctor. Do not crush, chew, or break the tablet; swallow it whole with a glass of water. Regular monitoring of blood sugar levels is essential while taking this medication to ensure optimal control and to detect any potential side effects.
  • Common side effects of GLISEN MF include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite. These side effects are usually mild and temporary. However, it's important to consult your doctor if these side effects persist or become bothersome. Serious but rare side effects can include lactic acidosis (a buildup of lactic acid in the blood) and hypoglycemia (low blood sugar). Be aware of the symptoms of hypoglycemia, such as sweating, shaking, rapid heartbeat, and confusion, and take appropriate action if they occur.
  • Before taking GLISEN MF, inform your doctor about your medical history, especially if you have kidney or liver disease, heart problems, or are pregnant or breastfeeding. Avoid alcohol consumption while taking this medication, as it can increase the risk of side effects. Always consult with your healthcare provider for personalized advice and to ensure that GLISEN MF is the right medication for you.

Uses of GLISEN MF 2MG TABLET 15'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving blood sugar control when used with diet and exercise
  • Management of insulin resistance in Polycystic Ovary Syndrome (PCOS) (off-label use)

How GLISEN MF 2MG TABLET 15'S Works

  • GLISEN MF 2MG TABLET 15'S is a combination medication designed to manage type 2 diabetes mellitus. It combines the synergistic effects of glimepiride and metformin to effectively control blood sugar levels. Glimepiride belongs to a class of drugs called sulfonylureas, while metformin is a biguanide.
  • Glimepiride primarily works by stimulating the release of insulin from the beta cells in the pancreas. Insulin is a hormone that helps glucose (sugar) move from the bloodstream into cells, where it can be used for energy. By increasing insulin secretion, glimepiride helps lower blood glucose levels, particularly after meals. The drug binds to specific receptors on the pancreatic beta cells, triggering a cascade of events that lead to insulin release. This mechanism is dependent on the presence of functioning beta cells in the pancreas.
  • Metformin, on the other hand, works through several different mechanisms to improve blood sugar control. First, it reduces the production of glucose in the liver by suppressing gluconeogenesis, the process by which the liver converts non-carbohydrate sources into glucose. Second, metformin increases insulin sensitivity in peripheral tissues, such as muscles and fat cells, allowing them to utilize glucose more effectively. This means that the same amount of insulin can lower blood sugar levels more efficiently. Third, metformin slows down the absorption of glucose from the intestines into the bloodstream, further contributing to its glucose-lowering effect.
  • The combination of glimepiride and metformin in GLISEN MF 2MG TABLET 15'S addresses multiple aspects of type 2 diabetes. Glimepiride helps to increase insulin secretion, while metformin improves insulin sensitivity and reduces glucose production in the liver. This dual action provides a more comprehensive approach to managing blood sugar levels compared to using either drug alone. Patients taking GLISEN MF 2MG TABLET 15'S should still adhere to a healthy diet and exercise regularly to maximize the benefits of the medication.
  • It's important to note that GLISEN MF 2MG TABLET 15'S, like other diabetes medications, should be used under the guidance of a healthcare professional. Regular monitoring of blood glucose levels and kidney function is necessary to ensure the medication is effective and safe. Patients should also be aware of potential side effects and interactions with other medications.

Side Effects of GLISEN MF 2MG TABLET 15'SArrow

Common side effects of Glisen MF 2mg Tablet may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and hypoglycemia (low blood sugar). Less common but potentially serious side effects can include lactic acidosis (symptoms may include muscle cramps, severe tiredness, trouble breathing), allergic reactions (rash, itching, swelling), liver problems (yellowing of the skin or eyes), and blood disorders (unexplained bruising or bleeding). It is important to contact your doctor immediately if you experience any severe or persistent side effects.

Safety Advice for GLISEN MF 2MG TABLET 15'SArrow

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Allergies

Allergies

Do not take Glisen MF 2mg Tablet 15's if you are allergic to it.

Dosage of GLISEN MF 2MG TABLET 15'SArrow

  • The recommended dosage of 'GLISEN MF 2MG TABLET 15'S' varies significantly based on individual patient needs and response to therapy. It's crucial to adhere strictly to your physician's instructions. Generally, the starting dose is low, often 1mg or 2mg of Glimepiride (the active ingredient in 'GLISEN MF 2MG TABLET 15'S'), taken once daily with breakfast or the first main meal. Metformin, the 'MF' component, is often started at 500mg once or twice daily, also with meals to minimize gastrointestinal upset.
  • Your doctor may gradually increase the dosage of both Glimepiride and Metformin, typically in increments of 1mg or 500mg respectively, every 1-2 weeks, based on your blood glucose levels. The maximum recommended daily dose of Glimepiride is usually 8mg, and for Metformin, it can go up to 2000mg per day, divided into multiple doses. Regular monitoring of blood glucose levels is essential during dosage adjustments to avoid hypoglycemia (low blood sugar) or hyperglycemia (high blood sugar).
  • It's important to maintain a consistent schedule for taking 'GLISEN MF 2MG TABLET 15'S', ideally at the same time(s) each day, with meals. This helps to maintain stable blood glucose levels throughout the day. If you miss a dose, do not double the next dose to compensate. Instead, take the missed dose as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Always consult with your doctor or pharmacist if you have any questions about your dosage or how to manage missed doses. Take 'GLISEN MF 2MG TABLET 15'S' only as per the prescription by your physician only.

What if I miss my dose of GLISEN MF 2MG TABLET 15'S?Arrow

  • If you miss a dose of GLISEN MF 2MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.
  • Consult your doctor if you have any concerns about missed doses.

How to store GLISEN MF 2MG TABLET 15'S?Arrow

  • Keep GLISEN MF 2MG TAB 1X15 away from the reach of children and pets.
  • Store GLISEN MF 2MG TAB 1X15 at room temperature.

Benefits of GLISEN MF 2MG TABLET 15'SArrow

  • GLISEN MF 2MG TABLET 15'S is a combination medicine primarily used to manage type 2 diabetes mellitus, particularly in individuals whose blood sugar levels are not adequately controlled by diet and exercise alone. It combines two active ingredients: Glimepiride and Metformin, each working through different mechanisms to lower blood glucose and improve glycemic control.
  • Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin. Insulin is a hormone that helps glucose move from the blood into cells, where it's used for energy. By increasing insulin secretion, Glimepiride effectively lowers blood sugar levels, especially after meals.
  • Metformin, a biguanide, works by decreasing glucose production in the liver and improving the body's sensitivity to insulin. It reduces the amount of glucose released into the bloodstream and helps cells utilize insulin more efficiently. This dual action makes GLISEN MF 2MG TABLET 15'S highly effective in managing blood sugar levels throughout the day.
  • The benefits of using GLISEN MF 2MG TABLET 15'S extend beyond just lowering blood sugar. Effective blood sugar control can significantly reduce the risk of long-term complications associated with diabetes, such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and cardiovascular problems like heart attack and stroke. By maintaining stable blood sugar levels, this medication contributes to overall health and well-being.
  • GLISEN MF 2MG TABLET 15'S is also beneficial because it targets multiple aspects of diabetes management. While Glimepiride helps the body release more insulin, Metformin ensures that the insulin is used more effectively. This synergistic effect often leads to better blood sugar control than using either medication alone.
  • Another advantage is its convenience. As a combination tablet, it simplifies the treatment regimen, reducing the number of pills a patient needs to take daily. This can improve adherence to the prescribed treatment plan, which is crucial for effective diabetes management.
  • Furthermore, Metformin, one of the components of GLISEN MF 2MG TABLET 15'S, has been associated with modest weight loss in some individuals. This can be a significant benefit for people with type 2 diabetes, as obesity often exacerbates the condition. While not a weight-loss drug, the potential for weight management is an added advantage.
  • In summary, GLISEN MF 2MG TABLET 15'S offers a comprehensive approach to managing type 2 diabetes by improving insulin secretion and utilization, reducing glucose production in the liver, and potentially aiding in weight management. This multifaceted action helps in achieving and maintaining stable blood sugar levels, thereby reducing the risk of diabetes-related complications and enhancing overall quality of life.
  • For individuals struggling to manage their blood sugar with lifestyle changes alone, GLISEN MF 2MG TABLET 15'S provides a powerful and convenient tool to achieve better glycemic control and reduce the long-term health risks associated with diabetes. Always take medicine as per doctor's prescription and medical advice.

How to use GLISEN MF 2MG TABLET 15'SArrow

  • GLISEN MF 2MG TABLET 15'S is a combination medication containing glimepiride and metformin, both of which help control blood sugar levels in people with type 2 diabetes. To get the most benefit from this medication, it's crucial to use it correctly and consistently as prescribed by your doctor.
  • The typical starting dose is one tablet once or twice daily, usually taken with meals to minimize the risk of stomach upset. Your doctor may adjust the dosage over time based on your blood sugar levels and how well you tolerate the medication. It's important to follow your doctor's instructions exactly and not to change the dosage on your own.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break it. Taking GLISEN MF 2MG TABLET 15'S at the same time(s) each day will help you remember to take it. If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
  • While taking GLISEN MF 2MG TABLET 15'S, it's important to monitor your blood sugar levels regularly as directed by your doctor or diabetes educator. This will help you track how well the medication is working and identify any potential problems. Be sure to inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins, as they may interact with GLISEN MF 2MG TABLET 15'S.
  • In addition to taking medication, making lifestyle changes such as eating a healthy diet, exercising regularly, and maintaining a healthy weight can also help improve blood sugar control. Talk to your doctor or a registered dietitian about developing a diabetes management plan that's right for you.
  • Be aware of the symptoms of low blood sugar (hypoglycemia), such as shakiness, sweating, dizziness, and confusion. If you experience these symptoms, eat or drink something sugary immediately, such as glucose tablets, fruit juice, or hard candy. Contact your doctor if you have frequent episodes of low blood sugar.
  • It is very important to adhere to the dosage and timing instructions provided by your healthcare provider for optimal effectiveness and safety.

Quick Tips for GLISEN MF 2MG TABLET 15'SArrow

  • Take GLISEN MF 2MG TABLET 15'S as prescribed by your doctor. It's crucial to adhere to the dosage and timing to effectively manage your blood sugar levels. Do not adjust the dosage yourself without consulting your healthcare provider.
  • GLISEN MF 2MG TABLET 15'S is typically taken with meals to minimize potential stomach upset. Consistent timing with meals will also aid in better glucose control throughout the day. If you miss a dose, take it with your next meal unless it is close to your next scheduled dose.
  • While taking GLISEN MF 2MG TABLET 15'S, monitor your blood sugar levels regularly as directed by your doctor. Keeping a log of your readings helps you and your doctor understand how the medication is working and whether any adjustments are needed. Share this log with your doctor during your check-ups.
  • Inform your doctor about all other medications, including over-the-counter drugs, herbal supplements, and vitamins, you are currently taking. Certain medications can interact with GLISEN MF 2MG TABLET 15'S, potentially affecting its efficacy or increasing the risk of side effects. Also, be sure to mention any existing medical conditions.
  • Lifestyle adjustments are vital for managing diabetes effectively alongside GLISEN MF 2MG TABLET 15'S. Follow a balanced diet, engage in regular physical activity, and maintain a healthy weight. Reducing stress and getting enough sleep also contribute significantly to better blood sugar control. Talk to your healthcare provider or a registered dietitian for personalized advice.

Food Interactions with GLISEN MF 2MG TABLET 15'SArrow

  • GLISEN MF 2MG TABLET 15'S should be taken with food to avoid stomach upset. Maintain a consistent meal schedule while taking this medication. Avoid excessive alcohol consumption, as it can increase the risk of low blood sugar. Inform your doctor about your dietary habits.

FAQs

What is Glisen MF 2mg Tablet 15's?Arrow

Glisen MF 2mg Tablet 15's is a combination of two medicines: Glimepiride and Metformin. It is used to lower high blood sugar levels in people with type 2 diabetes mellitus.

What is Glisen MF 2mg Tablet 15's used for?Arrow

Glisen MF 2mg Tablet 15's is used to treat type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.

What are the common side effects of Glisen MF 2mg Tablet 15's?Arrow

The common side effects of Glisen MF 2mg Tablet 15's include nausea, vomiting, diarrhea, stomach pain, and headache.

Is Glisen MF 2mg Tablet 15's safe during pregnancy?Arrow

The safety of Glisen MF 2mg Tablet 15's during pregnancy has not been established. Therefore, it should only be used if clearly needed and advised by a doctor.

Is Glisen MF 2mg Tablet 15's safe during breastfeeding?Arrow

It is not known whether Glisen MF 2mg Tablet 15's is excreted in breast milk. Therefore, breastfeeding mothers should consult their doctor before using this medicine.

How to store Glisen MF 2mg Tablet 15's?Arrow

Store Glisen MF 2mg Tablet 15's at room temperature, away from heat and moisture. Keep it out of the reach of children and pets.

Does Glisen MF 2mg Tablet 15's cause weight gain?Arrow

Glisen MF 2mg Tablet 15's can cause weight gain, especially if taken with other diabetes medications.

Is Glisen MF 2mg Tablet 15's safe for kidneys?Arrow

Glisen MF 2mg Tablet 15's should be used with caution in people with kidney disease, as it can worsen kidney problems.

Does Glisen MF 2mg Tablet 15's cause dizziness?Arrow

Glisen MF 2mg Tablet 15's can cause dizziness, especially when you first start taking it.

What happens if I miss a dose of Glisen MF 2mg Tablet 15's?Arrow

If you miss a dose of Glisen MF 2mg Tablet 15's, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Can I drink alcohol with Glisen MF 2mg Tablet 15's?Arrow

Drinking alcohol with Glisen MF 2mg Tablet 15's can increase the risk of low blood sugar.

How long does it take for Glisen MF 2mg Tablet 15's to work?Arrow

It may take a few days for Glisen MF 2mg Tablet 15's to start working.

What are the alternatives to Glisen MF 2mg Tablet 15's?Arrow

Alternatives to Glisen MF 2mg Tablet 15's include other diabetes medications such as sulfonylureas, metformin, thiazolidinediones, DPP-4 inhibitors, and SGLT2 inhibitors.

Should Glisen MF 2mg Tablet 15's be taken with food?Arrow

Glisen MF 2mg Tablet 15's is generally recommended to be taken with food.

How is Glimenorm MF 2mg Tablet different from Glisen MF 2mg Tablet?Arrow

Both Glimenorm MF 2mg Tablet and Glisen MF 2mg Tablet contain glimepiride and metformin, but they are made by different manufacturers and may have slightly different inactive ingredients.

References

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DrugBank: Gliclazide. This entry provides comprehensive information on Gliclazide, including its mechanism of action, uses, and interactions. Gliclazide is a sulfonylurea antidiabetic agent used in the treatment of type 2 diabetes mellitus.

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FDA Orange Book. While a direct entry for 'GLISEN MF' is unlikely, searching for its active ingredients (Gliclazide and Metformin) may yield relevant regulatory information regarding approved formulations and patents.

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European Medicines Agency (EMA). Search for Gliclazide or relevant combination products for European regulatory information, scientific assessments, and public assessment reports.

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PubMed: Search for 'Gliclazide' AND 'Metformin'. This will provide research articles related to the combined use of these medications, their efficacy, and safety profiles.

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UpToDate: Search for 'Gliclazide' and 'Metformin'. This resource provides evidence-based clinical information, including drug monographs, potential side effects, and drug interactions.

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ScienceDirect: Search for 'Gliclazide' and 'Metformin' for research articles, reviews, and clinical studies related to the drug and its ingredients.

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GLISEN MF 2MG TABLET 15'S with Glimepiride 2 MG + Metformin 500 MG

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