GLIMEFINE M2 TABLET 15'S
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GLIMEFINE M2 TABLET 15'S
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GLIMEFINE M2 TABLET 15'S

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GLIMEFINE M2 TABLET 15'S

By NEOCARDIAB CARE

MRP

94.5

₹80.32

15.01 % OFF

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About GLIMEFINE M2 TABLET 15'S

  • GLIMEFINE M2 Tablet is a combination medicine used to treat type 2 diabetes mellitus in adults. It combines two oral antidiabetic drugs: Glimepiride and Metformin. This medication is used when diet and exercise alone are not enough to control blood sugar levels.
  • Glimepiride is a sulfonylurea that works by increasing the release of insulin from the pancreas, helping to lower blood glucose. Metformin is a biguanide that reduces glucose production in the liver and improves insulin sensitivity, allowing the body to use insulin more effectively. Together, they provide better blood sugar control.
  • GLIMEFINE M2 is typically taken once or twice daily with meals to minimize stomach upset. The dosage is determined by your doctor based on your blood sugar levels and response to treatment. It is crucial to follow your doctor's instructions carefully and not to adjust the dose without consulting them. Regular monitoring of blood sugar levels is essential while taking this medication.
  • Common side effects of GLIMEFINE M2 may include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite. Hypoglycemia (low blood sugar) is also a potential side effect, especially if you skip meals or take other medications that lower blood sugar. It's important to be aware of the symptoms of hypoglycemia and have a readily available source of sugar, such as glucose tablets or fruit juice.
  • Before starting GLIMEFINE M2, inform your doctor about any other medical conditions you have, especially kidney or liver problems. This medication may not be suitable for everyone. It's also important to tell your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements, as they may interact with GLIMEFINE M2.
  • Consistent lifestyle changes, including a healthy diet, regular exercise, and weight management, are crucial for managing diabetes effectively. GLIMEFINE M2 should be used as part of a comprehensive diabetes management plan, not as a replacement for lifestyle modifications.

Uses of GLIMEFINE M2 TABLET 15'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Improving blood sugar control
  • Preventing complications associated with type 2 diabetes

How GLIMEFINE M2 TABLET 15'S Works

  • GLIMEFINE M2 TABLET 15'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: glimepiride and metformin, each working through different mechanisms to achieve optimal glycemic control. Glimepiride belongs to a class of drugs called sulfonylureas, while metformin is a biguanide.
  • Glimepiride primarily works by stimulating the release of insulin from the beta cells in the pancreas. When blood sugar levels rise, glimepiride prompts the pancreas to secrete more insulin. Insulin then facilitates the uptake of glucose from the bloodstream into cells, where it can be used for energy. This action helps lower blood sugar levels, particularly after meals. Glimepiride's effect is glucose-dependent, meaning it is more active when blood sugar is high and less active when blood sugar is low, reducing the risk of hypoglycemia (low blood sugar).
  • Metformin, on the other hand, works through several different pathways. First, it reduces the production of glucose in the liver by inhibiting gluconeogenesis (the process of creating glucose from non-carbohydrate sources). Second, it increases insulin sensitivity in peripheral tissues, such as muscle and fat, allowing cells to use insulin more effectively. This means that the body can utilize the available insulin more efficiently to lower blood sugar levels. Third, metformin slows down the absorption of glucose from the intestines after a meal, further contributing to blood sugar control. Unlike glimepiride, metformin does not directly stimulate insulin secretion, so it carries a lower risk of hypoglycemia when used alone.
  • By combining glimepiride and metformin, GLIMEFINE M2 TABLET 15'S addresses multiple aspects of type 2 diabetes. Glimepiride helps to increase insulin secretion to deal with high blood sugar, particularly after meals, while metformin reduces liver glucose production, enhances insulin sensitivity, and slows down glucose absorption. This synergistic effect provides more effective blood sugar control than either drug could achieve on its own. The combination helps to maintain stable blood sugar levels throughout the day, reducing the risk of both hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar). Regular monitoring of blood glucose levels and adherence to dietary and exercise recommendations are crucial for maximizing the benefits of GLIMEFINE M2 TABLET 15'S.

Side Effects of GLIMEFINE M2 TABLET 15'SArrow

Common side effects of GLIMEFINE M2 Tablet may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, hypoglycemia (low blood sugar), and headache. Less common but potentially serious side effects can include allergic reactions (rash, itching, swelling), liver problems (jaundice, dark urine), blood disorders (anemia, low white blood cell count, low platelet count), and lactic acidosis (muscle pain, difficulty breathing, stomach pain). Other possible side effects include dizziness, weakness, and visual disturbances. Consult your doctor immediately if you experience any severe or persistent side effects.

Safety Advice for GLIMEFINE M2 TABLET 15'SArrow

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Allergies

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Consult your Doctor

Dosage of GLIMEFINE M2 TABLET 15'SArrow

  • The recommended dosage of GLIMEFINE M2 TABLET 15'S varies depending on individual patient needs and response to treatment. It is crucial to adhere to your doctor's instructions regarding dosage and frequency. Typically, the starting dose is one tablet daily, usually taken with the first main meal to minimize gastrointestinal discomfort. Your physician may gradually increase the dosage based on your blood glucose levels, typically in increments of 1 mg glimepiride, at intervals of one to two weeks.
  • The maximum recommended daily dose of glimepiride is 8 mg. If adequate glycemic control is not achieved with GLIMEFINE M2 TABLET 15'S alone, your doctor may consider adding other antidiabetic medications. It is important to take GLIMEFINE M2 TABLET 15'S at the same time each day to maintain consistent blood glucose levels. Do not crush, chew, or break the tablet; swallow it whole with a glass of water.
  • If you miss a dose of GLIMEFINE M2 TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Regular monitoring of blood glucose levels is essential while taking GLIMEFINE M2 TABLET 15'S to assess the effectiveness of the medication and adjust the dosage accordingly. Consult your doctor if you experience any side effects or have any concerns about your dosage. Take 'GLIMEFINE M2 TABLET 15'S' only as per the prescription by your physician only

What if I miss my dose of GLIMEFINE M2 TABLET 15'S?Arrow

  • If you miss a dose of GLIMEFINE M2 TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the one you missed.

How to store GLIMEFINE M2 TABLET 15'S?Arrow

  • Keep GLIMEFINE M 2/500MG TAB 1X15 away from the reach of children and pets.
  • Store GLIMEFINE M 2/500MG TAB 1X15 at room temperature.

Benefits of GLIMEFINE M2 TABLET 15'SArrow

  • GLIMEFINE M2 TABLET 15'S offers a dual-action approach to managing type 2 diabetes, combining the power of glimepiride and metformin to effectively lower blood sugar levels. Glimepiride stimulates the pancreas to release more insulin, while metformin reduces glucose production in the liver and improves insulin sensitivity in the body's cells. This synergistic effect helps to achieve better glycemic control than either medication could accomplish alone.
  • One of the primary benefits of GLIMEFINE M2 TABLET 15'S is its ability to significantly reduce the risk of long-term complications associated with diabetes. By maintaining stable blood sugar levels, it helps prevent damage to vital organs such as the heart, kidneys, eyes, and nerves. This can lead to a reduced risk of heart disease, kidney failure, blindness, and nerve damage (neuropathy), all of which are serious and debilitating conditions.
  • GLIMEFINE M2 TABLET 15'S is particularly effective in improving insulin sensitivity, which is a key factor in managing type 2 diabetes. Metformin, one of its active ingredients, helps the body utilize insulin more efficiently, allowing glucose to enter cells for energy production. This not only lowers blood sugar levels but also helps to reduce insulin resistance, a common problem in individuals with type 2 diabetes.
  • The convenience of taking a single tablet containing two medications is another advantage of GLIMEFINE M2 TABLET 15'S. This simplifies the treatment regimen, making it easier for patients to adhere to their prescribed medication schedule. Improved adherence can lead to better blood sugar control and overall health outcomes. The reduced pill burden can also be particularly beneficial for individuals who are already taking multiple medications for other health conditions.
  • GLIMEFINE M2 TABLET 15'S can also contribute to weight management in some individuals. Metformin, in particular, has been shown to have a modest weight-loss effect in some patients. While it is not a weight-loss drug, it can help to prevent weight gain, which is often associated with diabetes and can make it more difficult to manage blood sugar levels. Maintaining a healthy weight is an important part of overall diabetes management.
  • Beyond its direct effects on blood sugar levels, GLIMEFINE M2 TABLET 15'S can also improve overall metabolic health. By reducing glucose toxicity and improving insulin sensitivity, it can help to lower triglyceride levels, improve cholesterol profiles, and reduce the risk of metabolic syndrome, a cluster of conditions that increase the risk of heart disease, stroke, and diabetes.
  • GLIMEFINE M2 TABLET 15'S is often prescribed as part of a comprehensive diabetes management plan that includes lifestyle modifications such as diet and exercise. It works best when combined with a healthy diet, regular physical activity, and weight management strategies. Your doctor can provide personalized recommendations for diet and exercise that will complement the effects of GLIMEFINE M2 TABLET 15'S and help you achieve optimal blood sugar control.

How to use GLIMEFINE M2 TABLET 15'SArrow

  • GLIMEFINE M2 TABLET 15'S should be taken orally, usually once daily, with or immediately following your first main meal of the day. This helps to minimize the risk of stomach upset and also aligns with how your body processes food and manages blood sugar levels. It is crucial to swallow the tablet whole with a full glass of water; do not crush, chew, or break it, as this can affect how the medication is released and potentially impact its effectiveness and safety.
  • The dosage of GLIMEFINE M2 TABLET 15'S will be determined by your doctor based on your individual needs, including your blood glucose levels, kidney function, and other medications you may be taking. It's important to adhere strictly to the prescribed dosage and timing. Do not increase or decrease the dose without consulting your doctor, even if you feel your blood sugar is well-controlled or not improving.
  • Consistency is key for optimal results. Try to take GLIMEFINE M2 TABLET 15'S at the same time each day to help you remember and maintain a consistent level of medication in your bloodstream. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one.
  • While taking GLIMEFINE M2 TABLET 15'S, it's crucial to monitor your blood glucose levels regularly, as advised by your doctor or diabetes educator. This will help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Report any unusual symptoms or side effects to your doctor promptly. These may include symptoms of low blood sugar (hypoglycemia), such as sweating, shaking, dizziness, or confusion. Also, maintain a healthy diet and regular exercise as advised by your healthcare provider, which are critical to managing diabetes effectively and ensuring GLIMEFINE M2 TABLET 15'S works optimally.
  • It's crucial to follow all instructions provided by your doctor or pharmacist and to read the medication guide carefully before starting GLIMEFINE M2 TABLET 15'S. If you have any questions or concerns about how to take the medication, do not hesitate to ask your healthcare provider for clarification.

Quick Tips for GLIMEFINE M2 TABLET 15'SArrow

  • Take GLIMEFINE M2 TABLET 15'S as prescribed by your doctor, usually once daily with the first main meal to minimize gastrointestinal side effects. Swallow the tablet whole with a full glass of water and do not crush, chew, or break it.
  • Follow your doctor's instructions carefully regarding diet and exercise while taking GLIMEFINE M2 TABLET 15'S. Maintaining a consistent carbohydrate intake and regular physical activity are crucial for effective blood sugar control and preventing hypoglycemia (low blood sugar).
  • Monitor your blood sugar levels regularly, as advised by your healthcare provider, especially during the initial weeks of treatment with GLIMEFINE M2 TABLET 15'S. Keep a log of your readings to help your doctor adjust your dosage if needed. Report any unusual fluctuations or persistent high or low readings promptly.
  • Be aware of the symptoms of hypoglycemia (low blood sugar), such as sweating, shakiness, dizziness, rapid heartbeat, and confusion. Carry a source of fast-acting glucose (e.g., glucose tablets, juice, or hard candy) with you at all times and use it if you experience these symptoms. Inform your family and friends about how to recognize and treat hypoglycemia.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking before starting GLIMEFINE M2 TABLET 15'S, as they may interact with the medication and affect your blood sugar control. Pay close attention to possible interactions with medications like NSAIDs, certain antibiotics, and beta-blockers. Also, avoid excessive alcohol consumption, as it can increase the risk of hypoglycemia. Regularly consult with your physician regarding possible drug interactions.

Food Interactions with GLIMEFINE M2 TABLET 15'SArrow

  • It is advisable to take GLIMEFINE M2 TABLET 15'S with or immediately after a meal to prevent stomach upset and to help your body better absorb the medication. Avoid skipping meals while taking this medication, as it can lead to hypoglycemia (low blood sugar). Consistent timing of meals is recommended.

FAQs

What is Glimefine M2 Tablet 15'S?Arrow

Glimefine M2 Tablet 15'S is a combination of two medicines: Glimepiride and Metformin. It is used to treat type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.

What is Glimefine M2 Tablet 15'S used for?Arrow

Glimefine M2 Tablet 15'S is used to treat type 2 diabetes mellitus. It helps lower blood sugar levels.

What are the common side effects of Glimefine M2 Tablet 15'S?Arrow

Common side effects of Glimefine M2 Tablet 15'S include nausea, vomiting, diarrhea, abdominal pain, and headache.

How to store Glimefine M2 Tablet 15'S?Arrow

Store Glimefine M2 Tablet 15'S at room temperature, away from heat and moisture. Keep it out of reach of children and pets.

Should Glimefine M2 Tablet 15'S be taken with food?Arrow

Glimefine M2 Tablet 15'S is generally recommended to be taken with food. This reduces the likelihood of stomach upset and helps improve the absorption of the medication.

What happens if I miss a dose of Glimefine M2 Tablet 15'S?Arrow

If you miss a dose of Glimefine M2 Tablet 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.

Can Glimefine M2 Tablet 15'S cause weight gain?Arrow

Glimefine M2 Tablet 15'S can cause weight gain in some people. Talk to your doctor if you are concerned about this.

Is Glimefine M2 Tablet 15'S safe during pregnancy?Arrow

The safety of Glimefine M2 Tablet 15'S during pregnancy has not been established. It should only be used during pregnancy if clearly needed and under the supervision of a doctor.

Is Glimefine M2 Tablet 15'S safe during breastfeeding?Arrow

It is not known whether Glimefine M2 Tablet 15'S is excreted in breast milk. Consult your doctor before using it during breastfeeding.

What medications should I avoid while taking Glimefine M2 Tablet 15'S?Arrow

You should avoid certain medications while taking Glimefine M2 Tablet 15'S, such as certain antifungal medications (e.g., ketoconazole), some antibiotics (e.g., clarithromycin), and some heart medications (e.g., digoxin). Tell your doctor about all the medications you are taking.

What are other brands of Metformin?Arrow

Some other brands of Metformin include Glucophage, Fortamet, and Riomet.

What are other brands of Glimepiride?Arrow

Some other brands of Glimepiride include Amaryl and Diapiride.

What are the symptoms of an overdose of Glimefine M2 Tablet 15'S?Arrow

Symptoms of an overdose of Glimefine M2 Tablet 15'S include low blood sugar (hypoglycemia), nausea, vomiting, abdominal pain, and weakness.

Is Glimefine M2 Tablet 15'S safe for people with kidney disease?Arrow

Glimefine M2 Tablet 15'S should be used with caution in people with kidney disease. Talk to your doctor if you have kidney disease.

How does Glimefine M2 Tablet 15'S lower blood sugar?Arrow

Glimefine M2 Tablet 15'S lowers blood sugar in two ways: Glimepiride increases insulin secretion, and Metformin increases insulin sensitivity and reduces glucose production in the liver.

References

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FDA drug label for Metformin Hydrochloride. This document contains detailed information about the drug's pharmacology, clinical studies, indications, usage, contraindications, warnings, precautions, adverse reactions, and dosage and administration.

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DrugBank record for Metformin. A comprehensive resource on metformin, covering its mechanism of action, pharmacokinetics, drug interactions, and therapeutic uses.

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Effectiveness of metformin on glycemic control in patients with type 2 diabetes: A systematic review and meta-analysis. This research article provides an overview of the effectiveness of metformin

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Gliclazide: An Update on Its Mechanism of Action, Safety Profile and Clinical Usefulness in Type 2 Diabetes Mellitus. This research article provides an overview of the mechanism of action, safety and clinical use of Gliclazide.

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FDA drug label for Glimepiride. This document contains detailed information about the drug's pharmacology, clinical studies, indications, usage, contraindications, warnings, precautions, adverse reactions, and dosage and administration.

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DrugBank record for Glimepiride. A comprehensive resource on Glimepiride, covering its mechanism of action, pharmacokinetics, drug interactions, and therapeutic uses.

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