glyciphage g 2mg tablet 10's
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GLYCIPHAGE G 2MG TABLET 10'S

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GLYCIPHAGE G 2MG TABLET 10'S

By FRANCO-INDIAN PHARMACEUTICALS PVT LTD

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Content Reviewed By:

Dr. Amit Patel

, (MBBS)

Written By:

Ms. Kavita Desai

, (B.Pharm)

About GLYCIPHAGE G 2MG TABLET 10'S

  • Glyciphage G2 is an oral antidiabetic medicine commonly prescribed for the management of type 2 diabetes mellitus. It is a combination of two active ingredients: metformin, which belongs to the biguanide class, and glimepiride, which is a sulfonylurea. Together, these medicines help control blood glucose levels when diet and exercise alone are not sufficient. Metformin primarily works by reducing glucose production in the liver, decreasing absorption of glucose from the intestine, and improving the body’s sensitivity to insulin. Glimepiride acts mainly by stimulating the pancreas to release more insulin, thereby helping lower blood sugar. Glyciphage G2 is usually recommended for adults with type 2 diabetes, particularly when single-drug therapy does not provide adequate glycemic control. It is generally taken once or twice daily with meals, as advised by a healthcare professional, to reduce the risk of stomach upset and low blood sugar. The exact dose and schedule are individualized based on blood sugar levels, other medical conditions, and concurrent medications, and must be determined only by a qualified doctor. Patients should not adjust the dose or stop the medicine on their own. Common side effects associated with Glyciphage G2 may include nausea, stomach discomfort, diarrhea, headache, dizziness, and low blood sugar (hypoglycemia), especially if meals are skipped, delayed, or if the patient engages in unusually strenuous exercise. Signs of hypoglycemia include sweating, tremors, hunger, palpitations, and confusion. Severe hypoglycemia can be dangerous and requires prompt treatment. Metformin, one of the components, carries a rare but serious risk of lactic acidosis, a condition characterized by buildup of lactic acid in the blood. This risk is higher in people with significant kidney or liver impairment, severe infections, dehydration, uncontrolled heart failure, or heavy alcohol use. Therefore, Glyciphage G2 should be used cautiously and only under medical supervision in such situations. Regular monitoring of blood glucose, kidney function, and liver function is important during treatment. Glyciphage G2 is not a substitute for a healthy lifestyle. Patients are advised to follow a balanced diet, maintain a healthy weight, exercise regularly, and attend regular follow-up visits with their doctor. Any symptoms such as persistent vomiting, abdominal pain, rapid breathing, unusual fatigue, yellowing of the skin or eyes, or swelling of the legs should be reported immediately, as they may indicate serious side effects or complications related to diabetes or the medication.

Uses of GLYCIPHAGE G 2MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Management of Polycystic Ovary Syndrome (PCOS) (off-label use)
  • Reducing the risk of heart disease (in some patients)

How GLYCIPHAGE G 2MG TABLET 10'S Works

  • GLYCIPHAGE G 2MG TABLET 10'S is a combination medication designed to effectively manage blood sugar levels in individuals with type 2 diabetes. It combines two powerful active ingredients: glimepiride and metformin. Each component works through distinct mechanisms to achieve optimal glycemic control. Glimepiride belongs to a class of drugs known as sulfonylureas. It primarily functions by stimulating the beta cells in the pancreas to release more insulin. Insulin is a crucial hormone that enables glucose (sugar) to move from the bloodstream into cells, where it can be used for energy. By increasing insulin secretion, glimepiride helps lower blood sugar levels, particularly after meals. This action is dependent on the presence of functioning beta cells in the pancreas. The effectiveness of glimepiride may diminish over time if beta cell function declines.
  • Metformin, on the other hand, is a biguanide. It operates through several mechanisms that improve the body's response to insulin and reduce glucose production. Firstly, metformin decreases the amount of glucose produced by the liver. The liver is a major source of glucose, and by inhibiting hepatic glucose production, metformin helps lower fasting blood sugar levels. Secondly, metformin enhances insulin sensitivity in peripheral tissues, such as muscles and fat. This means that cells become more responsive to insulin's signal, allowing them to take up glucose more efficiently from the bloodstream. Finally, metformin slows down the absorption of glucose from the intestines after a meal, further contributing to blood sugar control. Unlike glimepiride, metformin does not directly stimulate insulin secretion, which reduces the risk of hypoglycemia (low blood sugar).
  • The synergistic action of glimepiride and metformin in GLYCIPHAGE G 2MG TABLET 10'S provides comprehensive blood sugar control. Glimepiride addresses post-meal glucose spikes by stimulating insulin release, while metformin tackles both fasting blood sugar levels and insulin resistance. This combination is particularly beneficial for patients who require more intensive therapy to achieve their target blood sugar levels. It's crucial to remember that GLYCIPHAGE G 2MG TABLET 10'S should be used in conjunction with lifestyle modifications, including a healthy diet and regular exercise, to maximize its effectiveness. Regular monitoring of blood sugar levels is also essential to ensure optimal therapeutic outcomes and to adjust the dosage as needed under the guidance of a healthcare professional. Potential side effects should be discussed with your doctor, and any concerns should be promptly addressed.
  • In summary, GLYCIPHAGE G 2MG TABLET 10'S works by combining the insulin-releasing action of glimepiride with the insulin-sensitizing and glucose-lowering effects of metformin. This dual approach helps to regulate blood sugar levels effectively in individuals with type 2 diabetes, improving overall glycemic control and reducing the risk of long-term complications associated with the disease. Always consult your doctor or pharmacist for any questions.

Side Effects of GLYCIPHAGE G 2MG TABLET 10'SArrow

Common side effects of GLYCIPHAGE G 2MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, and a metallic taste in the mouth. Less common but potentially serious side effects include lactic acidosis (symptoms may include feeling very weak, tired or uncomfortable; unusual muscle pain, trouble breathing, stomach pain with nausea and vomiting, feeling cold, dizziness or lightheadedness, and a slow or irregular heartbeat), allergic reactions (rash, itching, swelling), hypoglycemia (low blood sugar - symptoms may include sweating, shaking, rapid heartbeat, hunger, blurred vision, dizziness, or tingling lips), and abnormalities in blood counts. Other possible side effects include headache, dizziness, and constipation. Contact your doctor immediately if you experience any severe or persistent side effects.

Safety Advice for GLYCIPHAGE G 2MG TABLET 10'SArrow

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Allergies

Contraindicated in known hypersensitivity

Glyciphage G2 should not be used in individuals with a known allergy to metformin, glimepiride, other sulfonylureas, sulfonamides, or any component of the formulation.

Dosage of GLYCIPHAGE G 2MG TABLET 10'SArrow

  • The dosage of GLYCIPHAGE G 2MG TABLET 10'S is highly individualized and should be determined by your physician based on your blood glucose levels, HbA1c, and response to treatment. Typically, the initial dose is low, and gradually increased to minimize gastrointestinal side effects. A common starting dose might be one tablet once or twice daily, taken with meals.
  • The maximum recommended daily dose of GLYCIPHAGE G 2MG TABLET 10'S should not be exceeded. It is crucial to adhere to your doctor's instructions regarding the timing and frequency of doses. Consistent timing, ideally with meals, helps maintain stable blood glucose levels throughout the day.
  • Your doctor may adjust your dosage over time based on your blood sugar readings. Regular monitoring of blood glucose is essential to determine the effectiveness of the medication and to guide dosage adjustments. Follow your doctor's advice closely and never change the dosage on your own.
  • If you miss a dose of GLYCIPHAGE G 2MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • Take 'GLYCIPHAGE G 2MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of GLYCIPHAGE G 2MG TABLET 10'S?Arrow

  • If you miss a dose of Glyciphage G 2mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store GLYCIPHAGE G 2MG TABLET 10'S?Arrow

  • Keep GLYCIPHAGE G 2MG TAB 1X10 away from the reach of children and pets.
  • Store GLYCIPHAGE G 2MG TAB 1X10 at room temperature.

Benefits of GLYCIPHAGE G 2MG TABLET 10'SArrow

  • GLYCIPHAGE G 2MG TABLET 10'S is a combination medicine primarily used to manage type 2 diabetes mellitus. Its dual-action formula combines the power of metformin and a sulfonylurea (glimepiride), offering a comprehensive approach to blood sugar control.
  • One of the primary benefits of GLYCIPHAGE G 2MG TABLET 10'S is its ability to effectively lower blood glucose levels. Metformin reduces glucose production in the liver and improves insulin sensitivity, while glimepiride stimulates the pancreas to release more insulin. This synergistic effect leads to better glycemic control than either drug could achieve alone. This is crucial for preventing long-term complications of diabetes, such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and cardiovascular diseases.
  • Beyond just lowering blood sugar, GLYCIPHAGE G 2MG TABLET 10'S can help improve HbA1c levels, which is a measure of average blood sugar control over the past 2-3 months. Lowering HbA1c is a key goal in diabetes management, as it reduces the risk of complications.
  • GLYCIPHAGE G 2MG TABLET 10'S may offer a convenient dosing schedule compared to taking metformin and a sulfonylurea separately. This can improve adherence to the prescribed treatment plan, leading to better health outcomes. Improved adherence is essential for managing a chronic condition like type 2 diabetes effectively.
  • Metformin, one of the key ingredients in GLYCIPHAGE G 2MG TABLET 10'S, has been associated with modest weight loss in some individuals. This can be an added benefit for patients with type 2 diabetes who are overweight or obese, as weight management is an important part of diabetes care. Managing weight can also improve insulin sensitivity and overall metabolic health.
  • By effectively controlling blood sugar levels, GLYCIPHAGE G 2MG TABLET 10'S can help reduce the risk of cardiovascular complications associated with diabetes. High blood sugar can damage blood vessels and increase the risk of heart disease and stroke. Proper management of blood sugar levels is crucial for protecting cardiovascular health.
  • GLYCIPHAGE G 2MG TABLET 10'S can improve overall quality of life for people with type 2 diabetes. By helping manage blood sugar levels, it can reduce symptoms such as fatigue, frequent urination, and excessive thirst. Improved symptom control can lead to increased energy levels and a better overall sense of well-being.
  • GLYCIPHAGE G 2MG TABLET 10'S offers a cost-effective treatment option compared to some newer diabetes medications. This can be an important consideration for patients who need long-term treatment for type 2 diabetes. Affordable medication options can help ensure that more people have access to the care they need.

How to use GLYCIPHAGE G 2MG TABLET 10'SArrow

  • GLYCIPHAGE G 2MG TABLET 10'S should be taken orally, preferably with meals, to minimize the risk of stomach upset. The dosage and timing are determined by your doctor, based on your blood sugar levels and response to treatment. It's crucial to follow your doctor's instructions precisely. Do not crush, chew, or break the tablet; swallow it whole with a full glass of water.
  • Consistency is key when taking GLYCIPHAGE G 2MG TABLET 10'S. Try to take it at the same time(s) each day to maintain a steady level of medication in your bloodstream. If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • During treatment with GLYCIPHAGE G 2MG TABLET 10'S, it's important to monitor your blood sugar levels regularly as directed by your healthcare provider. This helps ensure the medication is working effectively and allows for timely adjustments to your treatment plan if needed. Also, adhere to any dietary and exercise recommendations provided by your doctor or a registered dietitian. A healthy lifestyle, including a balanced diet and regular physical activity, can significantly improve blood sugar control and overall health.
  • Inform your doctor about all other medications, including over-the-counter drugs, herbal supplements, and vitamins, you are taking. Some medications can interact with GLYCIPHAGE G 2MG TABLET 10'S, potentially affecting its effectiveness or increasing the risk of side effects. If you experience any unusual symptoms or side effects, such as persistent nausea, vomiting, abdominal pain, or unexplained fatigue, contact your doctor immediately. Do not stop taking GLYCIPHAGE G 2MG TABLET 10'S without consulting your doctor, as this could lead to a rise in blood sugar levels.

Quick Tips for GLYCIPHAGE G 2MG TABLET 10'SArrow

  • Take GLYCIPHAGE G 2MG TABLET 10'S as prescribed by your doctor. This medication is typically taken with meals to minimize stomach upset. Consistent timing is key for maintaining stable blood sugar levels. Don't crush or chew the tablet; swallow it whole with a glass of water.
  • Follow a balanced diet and exercise regularly while taking GLYCIPHAGE G 2MG TABLET 10'S. This medicine works best when combined with lifestyle changes. Focus on incorporating whole grains, lean proteins, and plenty of fruits and vegetables into your meals. Aim for at least 30 minutes of moderate-intensity exercise most days of the week.
  • Monitor your blood sugar levels regularly as directed by your healthcare provider. Keeping a record of your blood sugar readings can help you and your doctor adjust your treatment plan as needed. Be aware of the symptoms of both high and low blood sugar, and know how to manage them.
  • Stay hydrated by drinking plenty of water throughout the day. Adequate hydration supports overall health and helps your kidneys function properly, which is especially important when taking medications like GLYCIPHAGE G 2MG TABLET 10'S. Limit sugary drinks and opt for water, herbal tea, or unsweetened beverages.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking. Drug interactions can affect how GLYCIPHAGE G 2MG TABLET 10'S works and increase the risk of side effects. This includes over-the-counter medications and any alternative therapies you are using. Do not start or stop any medication without consulting your doctor first.

Food Interactions with GLYCIPHAGE G 2MG TABLET 10'SArrow

  • GLYCIPHAGE G 2MG TABLET 10'S can be taken with or without food, but it is generally recommended to take it with meals to minimize the risk of gastrointestinal side effects like nausea, vomiting, or diarrhea.
  • Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis, a rare but serious side effect.
  • Maintain a consistent carbohydrate intake throughout the day. Avoid skipping meals, as this can lead to hypoglycemia (low blood sugar).
  • If you are following a specific diet plan, such as a low-carb or ketogenic diet, consult your doctor to adjust the dosage of GLYCIPHAGE G 2MG TABLET 10'S accordingly.

FAQs

What is Glyciphage G 2mg Tablet used for?Arrow

Glyciphage G 2mg Tablet is primarily used to treat type 2 diabetes mellitus, especially in people whose blood sugar levels are not controlled by diet and exercise alone. It helps to lower blood sugar levels.

How does Glyciphage G 2mg Tablet work?Arrow

Glyciphage G 2mg Tablet works by improving the body's sensitivity to insulin and decreasing the amount of glucose produced by the liver. It also helps in delaying the absorption of glucose from the intestines.

What are the common side effects of Glyciphage G 2mg Tablet?Arrow

Common side effects may include nausea, vomiting, diarrhea, stomach pain, and loss of appetite. These side effects are usually mild and temporary.

Can I take Glyciphage G 2mg Tablet if I have kidney problems?Arrow

It is generally not recommended to take Glyciphage G 2mg Tablet if you have kidney problems, as it can worsen the condition. Consult your doctor for advice.

What should I do if I miss a dose of Glyciphage G 2mg Tablet?Arrow

If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

Can Glyciphage G 2mg Tablet be used during pregnancy?Arrow

It's important to consult your doctor before using Glyciphage G 2mg Tablet during pregnancy. Insulin is usually preferred for managing blood sugar during pregnancy.

Can Glyciphage G 2mg Tablet be taken with other medications?Arrow

Glyciphage G 2mg Tablet can interact with other medications. Inform your doctor about all the medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins.

What should I avoid while taking Glyciphage G 2mg Tablet?Arrow

Avoid excessive alcohol consumption as it can increase the risk of side effects such as lactic acidosis. Also, maintain a healthy diet and exercise regularly.

How should Glyciphage G 2mg Tablet be stored?Arrow

Store Glyciphage G 2mg Tablet at room temperature, away from moisture and direct sunlight. Keep it out of reach of children.

Can Glyciphage G 2mg Tablet cause hypoglycemia (low blood sugar)?Arrow

Glyciphage G 2mg Tablet can cause hypoglycemia, especially when taken with other diabetes medications or insulin. It's important to monitor your blood sugar levels regularly.

What is the difference between Glyciphage G 2mg Tablet and other metformin tablets?Arrow

Glyciphage G 2mg Tablet is a brand name for a medication containing metformin. The main difference between different metformin tablets often lies in the brand, the specific formulation (immediate release vs. extended release), and the manufacturer.

Can Glyciphage G 2mg Tablet cause weight loss?Arrow

Glyciphage G 2mg Tablet may lead to modest weight loss in some individuals, but it is not primarily a weight loss medication. It mainly helps in controlling blood sugar levels.

What are the symptoms of lactic acidosis, a rare but serious side effect of Glyciphage G 2mg Tablet?Arrow

Symptoms of lactic acidosis include nausea, vomiting, abdominal pain, muscle cramps, severe tiredness, and difficulty breathing. Seek immediate medical attention if you experience these symptoms.

How long does it take for Glyciphage G 2mg Tablet to start working?Arrow

Glyciphage G 2mg Tablet starts working within a few days to weeks. However, it may take several weeks to see the full effect on blood sugar levels. Consistency in taking the medication as prescribed is important.

Is Glyciphage G 2mg Tablet safe for long-term use?Arrow

Glyciphage G 2mg Tablet is generally safe for long-term use when taken as prescribed and monitored by a healthcare professional. Regular check-ups are necessary to monitor kidney function and vitamin B12 levels.

What is Glyciphage G2 used for?Arrow

Glyciphage G2 is used to manage blood sugar levels in adults with type 2 diabetes mellitus. It is prescribed when diet, exercise, and single-drug therapy are not sufficient to control blood glucose. By combining metformin and glimepiride, it helps reduce high blood sugar and lowers the risk of diabetes-related complications such as nerve damage, kidney damage, eye problems, and cardiovascular disease when used as part of a comprehensive treatment plan.

How does Glyciphage G2 work in the body?Arrow

Glyciphage G2 contains metformin and glimepiride, which work through complementary mechanisms. Metformin decreases glucose production in the liver, reduces absorption of glucose from the intestines, and improves the body’s response to insulin. Glimepiride stimulates the pancreatic beta cells to release more insulin. Together, these actions help lower fasting and post-meal blood sugar levels and improve overall glycemic control in type 2 diabetes.

Can Glyciphage G2 be used in patients with liver problems?Arrow

Glyciphage G2 should be used with great caution in patients with liver disease. Metformin can increase the risk of lactic acidosis in people with significant hepatic impairment, and glimepiride metabolism may also be affected. In moderate to severe liver dysfunction, this combination is often avoided. Patients with any history of liver disease, hepatitis, cirrhosis, or unexplained jaundice must inform their doctor before starting Glyciphage G2. Liver function tests may be required before and during treatment, and any symptoms such as yellowing of the skin or eyes, dark urine, or persistent fatigue should be reported immediately.

Is Glyciphage G2 safe for patients with kidney disease?Arrow

Use of Glyciphage G2 in patients with kidney disease requires careful medical assessment. Metformin is eliminated mainly through the kidneys, and reduced kidney function increases the risk of lactic acidosis, a rare but serious side effect. In moderate to severe renal impairment, metformin-containing products are usually contraindicated or require strict dose adjustment and close monitoring. Patients with any history of kidney problems, reduced urine output, or those on nephrotoxic medicines should inform their doctor. Kidney function tests, such as serum creatinine and estimated glomerular filtration rate, are typically checked before starting and periodically during therapy.

Can I take Glyciphage G2 during pregnancy?Arrow

The use of Glyciphage G2 during pregnancy is generally not preferred unless specifically recommended by a specialist. Glimepiride, a sulfonylurea, can cross the placenta and may cause low blood sugar in the newborn. For pregnant women with diabetes, insulin is usually the treatment of choice, as it has a more established safety profile. If you are planning a pregnancy, suspect you are pregnant, or become pregnant while taking Glyciphage G2, you should contact your doctor promptly. Your treatment plan may need to be changed to ensure optimal blood sugar control and safety for both mother and baby.

Is Glyciphage G2 safe while breastfeeding?Arrow

Glyciphage G2 is generally not recommended during breastfeeding without specific medical advice. Metformin can pass into breast milk in small amounts, and glimepiride may also be excreted, potentially causing low blood sugar in the nursing infant. If treatment for diabetes is required while breastfeeding, your doctor will weigh the benefits and risks and may suggest alternative therapies, such as insulin or metformin alone, depending on your clinical situation. Do not breastfeed while taking Glyciphage G2 unless your healthcare provider has clearly advised it and is monitoring both you and your baby.

Can I drive or operate machines while taking Glyciphage G2?Arrow

Glyciphage G2 can sometimes cause low blood sugar, especially if meals are skipped, physical activity is increased unexpectedly, or other antidiabetic medicines are used concurrently. Hypoglycemia may lead to symptoms such as dizziness, blurred vision, confusion, or difficulty concentrating, which can impair your ability to drive or operate machinery safely. Until you know how Glyciphage G2 affects you, use caution when driving or performing tasks that require alertness. If you experience symptoms of low blood sugar, avoid driving and treat the hypoglycemia promptly according to your doctor’s advice.

Can I drink alcohol while taking Glyciphage G2?Arrow

Alcohol consumption should be limited or avoided while taking Glyciphage G2. Alcohol can increase the risk of hypoglycemia when combined with glimepiride and can also enhance the risk of lactic acidosis associated with metformin, particularly in people with liver or kidney problems, dehydration, or poor nutritional status. Binge drinking or regular heavy alcohol use is especially dangerous. If you choose to drink, discuss it with your doctor, keep intake minimal, avoid drinking on an empty stomach, and monitor your blood sugar closely.

What should I do if I have allergies or had a reaction to similar medicines?Arrow

If you have a known allergy to metformin, glimepiride, other sulfonylureas, sulfonamides, or any of the excipients in Glyciphage G2, you should not take this medicine. Signs of an allergic reaction may include rash, itching, swelling of the face, lips, tongue, or throat, severe dizziness, or difficulty breathing. Inform your doctor about any previous drug allergies or severe skin reactions before starting therapy. If you develop any of these symptoms after taking Glyciphage G2, stop the medicine and seek immediate medical attention.

What are the common side effects of Glyciphage G2 and when should I seek medical help?Arrow

Common side effects of Glyciphage G2 include nausea, vomiting, abdominal discomfort, diarrhea, loss of appetite, headache, and dizziness. Hypoglycemia is also a frequent concern, especially if meals are missed or delayed. Mild gastrointestinal symptoms often improve as the body adjusts to the medicine. However, you should seek medical help immediately if you experience signs of severe hypoglycemia such as confusion, seizures, or loss of consciousness, or symptoms suggestive of lactic acidosis, including rapid breathing, severe weakness, muscle pain, unusual sleepiness, or persistent abdominal pain. Yellowing of the skin or eyes, dark urine, or swelling of the legs should also be reported promptly, as they may indicate liver or kidney problems or other serious conditions.

References

Book Icon

DrugBank: Metformin. Comprehensive information on Metformin, including its mechanism of action, pharmacology, and interactions.

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FDA Prescribing Information for Metformin Hydrochloride Tablets. Official FDA label providing detailed information on usage, dosage, and safety.

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National Center for Biotechnology Information (NCBI): Metformin: An old but still the best treatment for type 2 diabetes. A review of metformin's efficacy and mechanisms.

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European Medicines Agency (EMA): Metformin-containing medicinal products. Information on regulatory actions and scientific evaluations of metformin.

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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