GLYREE M 2MG TABLET 10'S
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GLYREE M 2MG TABLET 10'S

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GLYREE M 2MG TABLET 10'S

By IPCA LABORATORIES LIMITED

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176.35

₹149.9

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About GLYREE M 2MG TABLET 10'S

  • GLYREE M 2MG TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus in adults. It combines two oral antidiabetic medicines: Glimepiride and Metformin. By improving insulin sensitivity and lowering blood glucose levels, it aids in managing blood sugar levels.
  • Glimepiride belongs to a class of drugs called sulfonylureas. It functions by boosting the amount of insulin secreted by the pancreas, which in turn lowers blood glucose. Metformin, a biguanide, acts by decreasing the amount of glucose produced by the liver, improving insulin sensitivity, and boosting glucose absorption by muscles. Together, they offer better glycemic control than either medication alone.
  • This medicine is usually taken once or twice daily with meals. Your doctor will determine the appropriate dosage and timing based on your specific requirements and medical condition. It is crucial to take it consistently at the same time(s) each day to maintain a steady level of medication in your blood.
  • Common side effects of GLYREE M 2MG TABLET 10'S may include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite. Hypoglycemia (low blood sugar) is another possible side effect, especially if you skip a meal or engage in strenuous exercise. To prevent hypoglycemia, it's important to eat regularly and carry a source of quick-acting glucose, such as glucose tablets or juice.
  • Before taking GLYREE M 2MG TABLET 10'S, inform your doctor about all your medical conditions, including kidney or liver problems, heart disease, or any other medications you are taking. It is also important to let your doctor know if you are pregnant or breastfeeding. This medicine is not recommended for patients with type 1 diabetes or diabetic ketoacidosis.

Uses of GLYREE M 2MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • As an adjunct to diet and exercise
  • Improving insulin sensitivity
  • Improving blood sugar control
  • Managing insulin resistance in polycystic ovary syndrome (PCOS) (off-label use)

How GLYREE M 2MG TABLET 10'S Works

  • GLYREE M 2MG TABLET 10'S is a combination medication designed to effectively manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: glimepiride and metformin. Each component works through distinct mechanisms to achieve optimal glycemic control.
  • Glimepiride belongs to a class of drugs called sulfonylureas. It primarily functions by stimulating the beta cells in the pancreas to release more insulin. Insulin is a crucial hormone that enables cells to absorb glucose from the bloodstream, thereby lowering blood sugar levels. Glimepiride essentially enhances the body's own insulin secretion to combat hyperglycemia. By promoting insulin release, glimepiride helps to counteract insulin resistance and maintain healthy glucose metabolism. It is particularly effective in patients whose pancreas still has some capacity to produce insulin.
  • Metformin, on the other hand, is a biguanide that operates through multiple pathways. Firstly, it reduces the production of glucose in the liver, which is a major source of blood sugar. It achieves this by inhibiting gluconeogenesis, the process by which the liver synthesizes glucose from non-carbohydrate sources. Secondly, metformin enhances insulin sensitivity in peripheral tissues, such as muscles and fat cells. This means that these tissues become more responsive to insulin's signal, allowing them to absorb glucose more efficiently. Thirdly, metformin slows down the absorption of glucose from the intestines, further contributing to the reduction of post-meal blood sugar spikes. Metformin's multifaceted action helps to control blood sugar levels throughout the day, regardless of meals.
  • The synergistic action of glimepiride and metformin allows for comprehensive blood sugar management. Glimepiride stimulates insulin release, while metformin reduces glucose production, enhances insulin sensitivity, and slows down glucose absorption. Together, they address different aspects of glucose metabolism, resulting in more effective control of blood sugar levels than either drug could achieve alone. This combination is often prescribed when diet and exercise alone are insufficient to maintain target blood sugar levels in patients with type 2 diabetes. GLYREE M 2MG TABLET 10'S should be taken as prescribed by a healthcare professional, usually once or twice daily with meals, to minimize gastrointestinal side effects and optimize its therapeutic benefits. Regular monitoring of blood sugar levels is essential to ensure the medication's effectiveness and to adjust the dosage as needed. It's also crucial to maintain a healthy lifestyle, including a balanced diet and regular physical activity, to maximize the benefits of GLYREE M 2MG TABLET 10'S.

Side Effects of GLYREE M 2MG TABLET 10'SArrow

Like all medicines, GLYREE M 2MG TABLET 10'S can cause side effects, although not everybody gets them. **Common Side Effects:** * Nausea * Vomiting * Diarrhea * Abdominal pain * Loss of appetite * Metallic taste * Hypoglycemia (low blood sugar) - symptoms may include sweating, tremor, anxiety, rapid heartbeat, dizziness, hunger, blurred vision, weakness * Headache **Uncommon Side Effects:** * Skin rash, itching, or hives * Photosensitivity (increased sensitivity to sunlight) * Dizziness * Fatigue * Constipation * Changes in blood cell counts (e.g., leukopenia, thrombocytopenia, agranulocytosis) - may increase risk of infection or bleeding * Liver problems (e.g., jaundice) - symptoms may include yellowing of the skin or eyes, dark urine, pale stools * Visual disturbances * Weight gain **Rare Side Effects:** * Allergic reactions (e.g., angioedema, anaphylaxis) - symptoms may include swelling of the face, lips, tongue, or throat, difficulty breathing, rash * Severe skin reactions (e.g., Stevens-Johnson syndrome, toxic epidermal necrolysis) - symptoms may include blistering and peeling of the skin * Impaired liver function and hepatitis * SIADH (syndrome of inappropriate antidiuretic hormone secretion) - can lead to low sodium levels in the blood * Lactic acidosis (especially in patients with kidney problems) - symptoms may include nausea, vomiting, abdominal pain, muscle cramps, severe tiredness, and difficulty breathing **Important Considerations:** * This is not a complete list of side effects. If you experience any unusual symptoms while taking GLYREE M 2MG TABLET 10'S, talk to your doctor or pharmacist. * The risk of hypoglycemia may be increased if you skip meals, exercise strenuously, or drink alcohol. * Certain medical conditions or medications may increase the risk of side effects. **Seek immediate medical attention if you experience any of the following:** * Severe allergic reaction * Severe skin reaction * Symptoms of lactic acidosis * Signs of liver problems

Safety Advice for GLYREE M 2MG TABLET 10'SArrow

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Allergies

Caution

Use caution if you have allergies to this medicine and consult a doctor before using.

Dosage of GLYREE M 2MG TABLET 10'SArrow

  • The recommended dosage of 'GLYREE M 2MG TABLET 10'S' varies depending on individual patient needs, blood glucose levels, and response to treatment. It is crucial to adhere strictly to your physician's instructions regarding dosage and administration. Typically, the starting dose is one tablet once or twice daily, taken with meals to minimize gastrointestinal side effects. Your doctor may gradually increase the dosage as needed to achieve optimal blood glucose control.
  • The maximum recommended daily dose of 'GLYREE M 2MG TABLET 10'S' should not exceed the amount prescribed by your doctor. It's important to maintain a consistent dosing schedule to ensure stable blood glucose levels throughout the day. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • Factors such as age, kidney function, and other medical conditions may influence the appropriate dosage of 'GLYREE M 2MG TABLET 10'S'. Regular monitoring of blood glucose levels is essential to assess the effectiveness of the medication and make any necessary dosage adjustments. It is important to inform your doctor about all other medications, including over-the-counter drugs and herbal supplements, as they may interact with 'GLYREE M 2MG TABLET 10'S'.
  • Take 'GLYREE M 2MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of GLYREE M 2MG TABLET 10'S?Arrow

  • If you miss a dose of GLYREE M 2MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store GLYREE M 2MG TABLET 10'S?Arrow

  • Keep GLYREE M 2MG TAB 1X10 away from the reach of children and pets.
  • Store GLYREE M 2MG TAB 1X10 at room temperature.

Benefits of GLYREE M 2MG TABLET 10'SArrow

  • GLYREE M 2MG TABLET 10'S is a combination medicine used to effectively manage type 2 diabetes mellitus. It combines two powerful antidiabetic drugs, glimepiride and metformin, to provide comprehensive blood sugar control. This dual-action approach addresses multiple aspects of diabetes management, leading to improved health outcomes.
  • Glimepiride stimulates the pancreas to release more insulin. Insulin is crucial for allowing glucose to enter cells from the bloodstream, thereby lowering blood sugar levels. By increasing insulin secretion, GLYREE M helps the body utilize glucose more efficiently, preventing hyperglycemia (high blood sugar).
  • Metformin works primarily by decreasing glucose production in the liver and improving the body's sensitivity to insulin. It reduces the amount of glucose released into the bloodstream and helps cells respond better to the insulin that is available. This dual mechanism of action complements glimepiride's effects, leading to better overall glycemic control.
  • By effectively lowering blood sugar levels, GLYREE M helps reduce the risk of serious diabetes-related complications. These complications can include cardiovascular diseases (such as heart attacks and strokes), nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy). Maintaining stable blood sugar levels is essential for preventing or delaying the onset of these long-term health issues.
  • GLYREE M contributes to improved energy levels and reduced fatigue. Uncontrolled diabetes often leads to persistent tiredness and weakness due to the body's inability to efficiently use glucose for energy. By helping to regulate blood sugar, this medicine ensures a more consistent and reliable energy supply, leading to increased vitality and overall well-being.
  • Effective blood sugar management with GLYREE M helps reduce excessive thirst and frequent urination, which are common symptoms of uncontrolled diabetes. As blood sugar levels normalize, the kidneys don't need to work as hard to filter out excess glucose, alleviating these uncomfortable symptoms.
  • GLYREE M can aid in weight management, particularly when combined with a healthy diet and regular exercise. Metformin, one of the components, has been shown to help some individuals manage their weight more effectively. Maintaining a healthy weight is crucial for managing diabetes and reducing the risk of related complications.
  • This medicine helps to stabilize HbA1c levels, which is a measure of average blood sugar control over the past 2-3 months. Regular monitoring of HbA1c is essential for assessing the effectiveness of diabetes treatment, and GLYREE M helps to keep these levels within the target range recommended by healthcare professionals.
  • GLYREE M simplifies diabetes management by combining two medications into a single tablet. This can improve adherence to treatment, as it reduces the pill burden and makes it easier for patients to follow their prescribed regimen. Improved adherence leads to better blood sugar control and improved health outcomes.
  • GLYREE M enhances overall quality of life by managing diabetes effectively. Stable blood sugar levels contribute to improved mood, better sleep, and increased ability to participate in daily activities. By alleviating the symptoms and complications of diabetes, this medicine helps patients live more fulfilling and active lives.
  • GLYREE M helps prevent/delay the onset of long-term complications such as: Kidney damage: By maintaining stable blood sugar levels, GLYREE M reduces the strain on the kidneys and helps prevent nephropathy. Nerve damage: Effective blood sugar control reduces the risk of neuropathy, preventing pain, numbness, and tingling in the extremities. Eye damage: Stable glucose levels can delay or prevent the development of retinopathy, protecting vision. Cardiovascular issues: Managing blood sugar reduces the risk of heart attacks, strokes, and other cardiovascular problems associated with diabetes.
  • GLYREE M, as part of a comprehensive diabetes management plan including diet and exercise, empowers individuals to take control of their health and improve their overall well-being.

How to use GLYREE M 2MG TABLET 10'SArrow

  • GLYREE M 2MG TABLET 10'S should be taken orally, usually once or twice daily, as prescribed by your doctor. It is generally recommended to take this medication with food to minimize the risk of stomach upset. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet unless specifically instructed by your healthcare provider, as this can affect how the medication is released and absorbed in your body.
  • The dosage of GLYREE M 2MG TABLET 10'S is individualized and depends on your blood sugar levels, response to treatment, and other medications you may be taking. It is crucial to follow your doctor's instructions precisely and not to adjust the dosage on your own. Regular monitoring of blood glucose levels is essential to determine the effectiveness of the medication and guide dosage adjustments.
  • Consistency is key when taking GLYREE M 2MG TABLET 10'S. Try to take it at the same time(s) each day to maintain a steady level of medication in your bloodstream. If you miss a dose, take it as soon as you remember unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • It's important to maintain a healthy lifestyle while taking GLYREE M 2MG TABLET 10'S. This includes following a balanced diet, engaging in regular physical activity, and managing stress levels. These lifestyle modifications can significantly improve blood sugar control and overall health. Also, inform your doctor about all other medications, including over-the-counter drugs, supplements, and herbal remedies, as they may interact with GLYREE M 2MG TABLET 10'S.
  • Before starting GLYREE M 2MG TABLET 10'S, tell your doctor if you have any kidney or liver problems, heart disease, or other medical conditions. Regular check-ups and lab tests, including blood glucose and kidney function tests, are necessary to monitor your health and the effectiveness of the treatment. Report any unusual side effects or symptoms to your doctor promptly.

Quick Tips for GLYREE M 2MG TABLET 10'SArrow

  • Take GLYREE M 2MG TABLET 10'S as prescribed by your doctor, usually once or twice daily with meals, to minimize stomach upset and maximize absorption. Consistency is key for optimal blood sugar control.
  • Monitor your blood glucose levels regularly as advised by your healthcare provider while taking GLYREE M 2MG TABLET 10'S. This helps you understand how the medication and your lifestyle choices impact your blood sugar, enabling informed adjustments to your diet and exercise.
  • Inform your doctor about all other medications, including herbal supplements and over-the-counter drugs, you are currently taking before starting GLYREE M 2MG TABLET 10'S. This prevents potential drug interactions that could affect the medication's efficacy or increase the risk of side effects.
  • Follow a balanced diet and exercise regularly while on GLYREE M 2MG TABLET 10'S. This medication works best when combined with a healthy lifestyle, improving overall blood sugar control and reducing the risk of diabetes-related complications.
  • Be aware of the symptoms of hypoglycemia (low blood sugar), such as sweating, shaking, rapid heartbeat, and confusion, while taking GLYREE M 2MG TABLET 10'S. Carry a source of fast-acting glucose, like glucose tablets or fruit juice, with you at all times to treat hypoglycemia promptly. If symptoms are severe or you lose consciousness, seek immediate medical attention.
  • Stay hydrated by drinking plenty of water throughout the day while taking GLYREE M 2MG TABLET 10'S. Adequate hydration supports overall health and helps prevent dehydration, which can sometimes be a side effect of certain diabetes medications.
  • If you experience persistent side effects such as nausea, diarrhea, or abdominal discomfort while taking GLYREE M 2MG TABLET 10'S, consult your doctor. They can assess your symptoms and adjust your dosage or recommend alternative treatments as needed.

Food Interactions with GLYREE M 2MG TABLET 10'SArrow

  • While taking GLYREE M 2MG TABLET 10'S, it's generally advisable to maintain a consistent dietary pattern. This medication can be taken with or without food, but taking it with meals may help reduce the chance of stomach upset. Avoid excessive alcohol consumption, as it can increase the risk of low blood sugar (hypoglycemia) and may also interact negatively with the medication. If you have specific dietary concerns or conditions, such as gastroparesis, consult your doctor for personalized advice regarding food intake while on GLYREE M 2MG TABLET 10'S.

FAQs

What is GLYREE M 2MG TABLET 10'S used for?Arrow

GLYREE M 2MG TABLET 10'S is used to treat type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.

How does GLYREE M 2MG TABLET 10'S work?Arrow

GLYREE M 2MG TABLET 10'S is a combination of two medicines: Glimepiride and Metformin. Glimepiride belongs to the sulfonylurea class which works by increasing the release of insulin from the pancreas thereby lowering the blood sugar levels. Metformin belongs to the biguanides class which works by decreasing glucose production in the liver, delaying glucose absorption from the intestines and increasing the sensitivity to insulin.

What are the common side effects of GLYREE M 2MG TABLET 10'S?Arrow

The common side effects of GLYREE M 2MG TABLET 10'S include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.

Is GLYREE M 2MG TABLET 10'S safe for patients with kidney disease?Arrow

GLYREE M 2MG TABLET 10'S should be used with caution in patients with kidney disease. Dosage adjustment may be required. Please consult your doctor.

Is GLYREE M 2MG TABLET 10'S safe during pregnancy?Arrow

GLYREE M 2MG TABLET 10'S is not recommended during pregnancy. Please consult your doctor if you are pregnant or planning to become pregnant.

Is GLYREE M 2MG TABLET 10'S safe during breastfeeding?Arrow

GLYREE M 2MG TABLET 10'S is not recommended during breastfeeding. Please consult your doctor.

How should I take GLYREE M 2MG TABLET 10'S?Arrow

Take GLYREE M 2MG TABLET 10'S exactly as prescribed by your doctor. It is best to take it with food.

What happens if I miss a dose of GLYREE M 2MG TABLET 10'S?Arrow

If you miss a dose of GLYREE M 2MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Can GLYREE M 2MG TABLET 10'S cause weight gain?Arrow

GLYREE M 2MG TABLET 10'S can cause weight gain in some patients. Monitor your weight and talk to your doctor if you experience excessive weight gain.

Can I drink alcohol while taking GLYREE M 2MG TABLET 10'S?Arrow

Alcohol should be avoided while taking GLYREE M 2MG TABLET 10'S as it can lower blood sugar levels and cause other side effects.

What happens if I overdose on GLYREE M 2MG TABLET 10'S?Arrow

An overdose of GLYREE M 2MG TABLET 10'S can cause hypoglycemia (low blood sugar). Seek immediate medical attention if you suspect an overdose.

Can GLYREE M 2MG TABLET 10'S interact with other medications?Arrow

GLYREE M 2MG TABLET 10'S can interact with certain other medications. Tell your doctor about all the medicines you are taking, including prescription and over-the-counter medicines.

How should I store GLYREE M 2MG TABLET 10'S?Arrow

Store GLYREE M 2MG TABLET 10'S at room temperature, away from direct sunlight and heat. Keep it out of reach of children and pets.

Is GLYREE M 2MG TABLET 10'S safe for patients with heart conditions?Arrow

GLYREE M 2MG TABLET 10'S should be used with caution in patients with heart conditions. Inform your doctor about your heart problems.

What are the other medicines with the combination of Glimepiride and Metformin?Arrow

Some other medicines with the combination of Glimepiride and Metformin include Glimisave M, Amaryl M and Zoryl M.

References

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DrugBank: Glimepiride

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FDA Label: Glimepiride Tablets

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National Institutes of Health: Efficacy of metformin and glimepiride combination therapy on glycemic control in type 2 diabetes mellitus patients: A systematic review and meta-analysis

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ScienceDirect: Glimepiride - Drug Class Information

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Mayo Clinic: Metformin and Glipizide Combination

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WebMD: Glimepiride Oral

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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