LUPIXIMAB 500 INJECTION
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LUPIXIMAB 500 INJECTION
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LUPIXIMAB 500 INJECTION

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LUPIXIMAB 500 INJECTION

By LUPIN LIMITED

MRP

14689.5

₹11751.6

20 % OFF

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About LUPIXIMAB 500 INJECTION

  • LUPIXIMAB 500 INJECTION contains the active ingredient rituximab. It is used to treat several serious health conditions in adults. It can be used alone or with other medicines. It treats certain types of cancer like Non-Hodgkin's Lymphoma (a cancer affecting a type of white blood cell called B-lymphocytes) and Chronic Lymphocytic Leukemia (the most common type of leukemia that affects B-cells). It is also used for moderate to severe Rheumatoid Arthritis (an autoimmune disease where the body attacks its own joints) when given with methotrexate. Other uses include treating Granulomatosis with Polyangiitis or Microscopic Polyangiitis (conditions causing blood vessel inflammation, often affecting lungs and kidneys) in adults and children aged 2 years and older. It also helps treat moderate to severe Pemphigus Vulgaris (an autoimmune skin condition causing painful blisters on the skin, mouth, throat, and other areas). This medicine works by targeting specific cells in your body, like the B-cells, which are involved in these diseases.
  • LUPIXIMAB 500 INJECTION is a type of medicine called an anti-CD20 monoclonal antibody. You should not receive this injection if you are allergic to rituximab or any other ingredients, have a very weak immune system, or have a severe active infection. Tell your doctor if you have heart problems, heart failure, or breathing difficulties before starting this treatment. It's also important to discuss if you have ever had a Hepatitis B infection, as this medicine can sometimes cause the virus to become active again, which can be serious. Pregnancy and breastfeeding are usually not recommended while you are receiving this injection.
  • Common side effects of LUPIXIMAB 500 INJECTION can include signs of infection (like fever or chills), feeling dizzy, swelling in your face or body, itchy skin, diarrhea, increased sweating, or changes in blood pressure (either low or high). It's crucial to use reliable birth control during treatment and for 12 months after your last dose if you can become pregnant. This medicine can sometimes cause severe reactions during or within 24 hours after the infusion. These are called infusion reactions. Tell your doctor or nurse immediately if you experience any signs of an infusion reaction, such as high blood pressure, chest pain, headache, trouble breathing, vomiting, skin rash, or swelling of the throat or face. Close monitoring by healthcare professionals is important during and after administration to manage these potential side effects effectively.

Uses of LUPIXIMAB 500 INJECTION

  • Non-Hodgkin's lymphoma (NHL): A type of cancer starting in the lymphatic system.
  • Chronic lymphocytic leukemia (CLL): A slow-growing cancer affecting blood and bone marrow.
  • Rheumatoid Arthritis: A chronic inflammatory disorder affecting joints.
  • Granulomatosis with polyangiitis or microscopic polyangiitis: Rare disorders causing blood vessel inflammation.
  • Pemphigus vulgaris: A rare autoimmune disease causing skin and mucous membrane blistering.

Side Effects of LUPIXIMAB 500 INJECTION
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Side effects are unwanted symptoms caused by medicines like LUPIXIMAB 500 INJECTION. Even though all drugs can cause side effects, not everyone experiences them.

Safety Advice for LUPIXIMAB 500 INJECTION
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Pregnancy

Unsafe

LUPIXIMAB 500 INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.  

Dosage of LUPIXIMAB 500 INJECTION
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  • This medication, LUPIXIMAB 500 INJECTION, must only be given by a qualified doctor or nurse. It is very important that you do not try to inject this medicine yourself at home. To help prevent or lessen potential side effects, you will receive other medicines, known as pre-medication, before getting LUPIXIMAB 500 INJECTION. Your healthcare team will determine the correct amount of LUPIXIMAB 500 INJECTION you need and how long you will receive it. This decision is based on how serious your condition is and other individual factors. The medicine is given directly into your vein through a drip, which is called an intravenous infusion. During and after the infusion, you will be closely watched by medical staff to check for any reactions or side effects that might occur. This careful monitoring ensures your safety during the treatment process.

How to store LUPIXIMAB 500 INJECTION?
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  • Keep LUPIXIMAB 500MG INJ 50ML away from the reach of children and pets.
  • Store LUPIXIMAB 500MG INJ 50ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of LUPIXIMAB 500 INJECTION
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  • LUPIXIMAB 500 INJECTION is a targeted therapy that works by attaching to a marker called CD20 on specific white blood cells (B-lymphocytes).
  • In non-Hodgkin's lymphoma and chronic lymphocytic leukemia, it causes these problematic B-cells to die, helping to reduce cancer cell numbers.
  • For rheumatoid arthritis, it calms the immune system by targeting B-cells, reducing inflammation, stopping harmful substance production, and helping to manage joint damage, pain, and disease progression.

How to use LUPIXIMAB 500 INJECTION
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  • LUPIXIMAB 500 INJECTION must only be given by a trained healthcare professional, like a doctor or nurse, in a hospital or clinic setting. It is very important that you do not attempt to inject this medication yourself. Before you receive the LUPIXIMAB 500 INJECTION, your doctor or nurse will administer other medicines, known as pre-medications. These are given to help reduce the chance of experiencing certain possible side effects or reactions to the infusion. The specific dose you receive and how long you will need treatment will be carefully determined by your doctor. This decision is based on several factors, including your specific medical condition, how severe it is, your overall health, and how you respond to the treatment. The injection is given slowly into a vein through an intravenous (IV) infusion. During and after the infusion, healthcare staff will monitor you closely for any potential unwanted reactions or side effects to ensure your safety and well-being. Feel free to discuss any concerns you have with your healthcare team.

FAQs

What are the special precautions I should be aware of before starting treatment with LUPIXIMAB 500 INJECTION?

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Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are LUPIXIMAB 500 INJECTION infusion-related reactions?

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Infusion reactions occur during or within 24 hours after administering LUPIXIMAB 500 INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomiting, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during LUPIXIMAB 500 INJECTION?

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Your healthcare professional will monitor you carefully for unwanted side effects during the LUPIXIMAB 500 INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Does LUPIXIMAB 500 INJECTION suppress the immune system?

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Yes, it can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking LUPIXIMAB 500 INJECTION because it may cause drug-induced immunosuppression.

Is weight gain a side effect of LUPIXIMAB 500 INJECTION?

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Weight gain has been reported in patients treated with LUPIXIMAB 500 INJECTION for non-hodgkin’s lymphoma.

How does LUPIXIMAB 500 INJECTION interact with other drugs or vaccines?

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Avoid vaccines before and during therapy. Inform your physician if you have been vaccinated recently because LUPIXIMAB 500 INJECTION may cause drug-induced immunosuppression.

What urgent symptoms should I report to my doctor while taking LUPIXIMAB 500 INJECTION?

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Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease.

What is the active ingredient in LUPIXIMAB 500 INJECTION?

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LUPIXIMAB 500 INJECTION contains RITUXIMAB as its active ingredient.

Is LUPIXIMAB 500 INJECTION used to treat cancer?

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Yes, LUPIXIMAB 500 INJECTION is used to treat certain types of cancer.

Can LUPIXIMAB 500 INJECTION be used for Arthritis treatment?

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Yes, LUPIXIMAB 500 INJECTION is used to treat Arthritis.

Is LUPIXIMAB 500 INJECTION prescribed for Osteoporosis?

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Yes, LUPIXIMAB 500 INJECTION is prescribed for Osteoporosis.

References

Book Icon

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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Marketer / Manufacturer Details

LUPIN LIMITED

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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