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MABTAS N 500 INJECTION
MABTAS N 500 INJECTION
By INTAS PHARMACEUTICALS LIMITED
MRP
₹
42658.56
₹11500
73.04 % OFF
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Product Details
About MABTAS N 500 INJECTION
- MABTAS N 500 INJECTION contains the active ingredient rituximab. It is used to treat several serious medical conditions in adults. It can be used by itself or with other medicines to treat certain types of blood cancers: non-Hodgkin's lymphoma (a cancer that affects white blood cells called B-lymphocytes) and chronic lymphocytic leukemia (CLL), which is a common type of B-cell cancer. MABTAS N 500 INJECTION is also used to treat moderate to severe rheumatoid arthritis in adults, when used together with methotrexate. Rheumatoid arthritis is an autoimmune disease where the body's immune system mistakenly attacks its own joints. Furthermore, it is indicated for treating granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA) in adults and children aged 2 years and older. These are conditions where blood vessels become inflamed, often affecting organs like the lungs and kidneys. Finally, it treats moderate to severe pemphigus vulgaris, an autoimmune skin condition causing painful blisters on the skin and mucous membranes like the mouth, throat, and genitals.
- MABTAS N 500 INJECTION belongs to a group of medicines called anti-CD20 monoclonal antibodies. It works by targeting and attaching to a specific protein (CD20) found on the surface of B-cells. This helps the immune system destroy these B-cells, which can be beneficial in treating the mentioned conditions. Do not take this injection if you are allergic to rituximab or any other ingredients in this medicine. You should also avoid it if you have a severely weakened immune system or are currently fighting a severe active infection. It is crucial to inform your doctor about any history of heart problems, heart failure, or breathing difficulties before starting treatment, as these conditions may require careful monitoring. Be sure to also mention if you have ever had a hepatitis B infection. In some cases, this virus can become active again during or after treatment, which can be very serious. Pregnancy and breastfeeding are generally not advised while receiving this injection. Effective birth control methods should be used during treatment and for 12 months after your last dose if you could become pregnant.
- Common side effects you might experience with MABTAS N 500 INJECTION include signs of infection, a decrease in red blood cells (anemia), dizziness, swelling in the face or body, itchy skin, diarrhea, increased sweating, and changes in blood pressure (either low or high). This medicine can cause severe reactions, especially during or within 24 hours after it is given as an infusion. These are called infusion reactions. It is very important to tell your doctor or nurse immediately if you experience any symptoms of an infusion reaction, such as increased blood pressure, chest pain, headache, difficulty breathing, vomiting, skin rashes (like hives), or swelling of the throat or tongue. Your medical team will monitor you closely during the infusion and know how to manage these reactions. Regular check-ups and blood tests will also be necessary throughout your treatment course to monitor your response and check for potential issues.
Uses of MABTAS N 500 INJECTION
- A type of cancer that affects lymphocytes, a type of white blood cell in the immune system.
- A slow-growing cancer of a type of white blood cell called lymphocytes.
- A chronic inflammatory disorder that affects the joints.
- Rare diseases causing inflammation in blood vessels, affecting various organs.
- A rare autoimmune disease that causes blistering of the skin and mucous membranes.
Safety Advice for MABTAS N 500 INJECTION
Pregnancy
UnsafeMABTAS N 500 INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.
Dosage of MABTAS N 500 INJECTION
- MABTAS N 500 INJECTION must always be given by a trained doctor or nurse in a proper medical setting. It is very important that you do not try to give yourself this injection at home. Before receiving the MABTAS N 500 INJECTION, you will typically be given other medications, known as 'pre-medication'. These are administered beforehand to help minimise potential side effects or reactions that might occur during the treatment. Your doctor will carefully determine the correct dose and the length of your treatment course. This decision depends on several factors, including the specific condition being treated, its severity, your overall health status, and how your body responds to the medication. The injection is given as a slow drip directly into a vein, a process called intravenous infusion. During the infusion and afterwards, healthcare professionals will closely monitor you for any possible unwanted side effects, such as allergic reactions or changes in vital signs. Always follow your doctor's instructions regarding this treatment.
How to store MABTAS N 500 INJECTION?
- Keep MABTAS N 500MG INJ 50ML away from the reach of children and pets.
- Store MABTAS N 500MG INJ 50ML in a refrigerator (2 - 8°C). Do not freeze.
Benefits of MABTAS N 500 INJECTION
- MABTAS N 500 INJECTION is a targeted therapy that works by attaching to specific cells called B-lymphocytes which carry the CD20 protein. In certain blood cancers like Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL), this medicine triggers the death of cancerous B-cells and stops their uncontrolled growth, providing powerful anti-cancer effects.
- For autoimmune conditions like rheumatoid arthritis, MABTAS N 500 INJECTION helps by regulating the overactive immune system. It reduces the production of inflammatory substances and signals, such as rheumatoid factor and proinflammatory cytokines, and interferes with other immune responses that contribute to joint inflammation and damage, helping to manage symptoms and disease progression.
How to use MABTAS N 500 INJECTION
- This medication, MABTAS N 500 INJECTION, must only be given by a healthcare professional, such as a trained doctor or nurse. It is crucial that you do not attempt to inject this medication yourself. Giving it yourself could be dangerous and lead to serious problems.
- Before receiving your dose of MABTAS N 500 INJECTION, your doctor or nurse will give you other medicines. These are called pre-medications and are given to help prevent or lessen potential side effects or reactions that might occur during the treatment.
- The correct amount (dose) and how long you receive this treatment will be decided entirely by your doctor. They will consider your specific health condition, how severe it is, and other important factors unique to you.
- The medication is given directly into a vein through a slow drip, known as an intravenous infusion. This process usually takes several hours. While you are receiving the infusion, and for a period afterward, you will be closely watched by the healthcare team to ensure everything is going smoothly and to quickly manage any unexpected side effects that may arise. This treatment is typically administered in a hospital or clinic setting.
FAQs
<p style="text-align:justify;">What are the special precautions I should be aware of before starting treatment with MABTAS N 500 INJECTION?</p>
<p>Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure. </p>
<p style="text-align:justify;">What are MABTAS N 500 INJECTION infusion-related reactions?</p>
<p style="text-align:justify;">Infusion reactions occur during or within 24 hours after administering MABTAS N 500 INJECTION injection. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction. </p>
<p>What will be the most important thing to monitor during MABTAS N 500 INJECTION infusion?</p>
<p>Your healthcare professional will monitor you carefully for the unwanted side effects that occur during the MABTAS N 500 INJECTION infusion. You will be monitored for heart failure, increased blood pressure, or breathing failure. </p>
<p>What precautions should I take regarding vaccinations and infections while using MABTAS N 500 INJECTION?</p>
<p>Avoid vaccines before and during the therapy. Inform your physician if you have been vaccinated recently because MABTAS N 500 INJECTION may cause drug-induced immunosuppression. Vaccination with live virus vaccines is not recommended before or during the treatment for patients with rheumatoid arthritis. Inform your healthcare professional if you have any active infection during the treatment.</p>
<p>What symptoms should I report to my doctor while on MABTAS N 500 INJECTION therapy, and what about kidney disease?</p>
<p>Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. There is limited information available on the safety of this medicine in renal failure patients; inform your physician if you have kidney disease.</p>
<p>What is the active ingredient in MABTAS N 500 INJECTION?</p>
<p>The active ingredient in MABTAS N 500 INJECTION is RITUXIMAB.</p>
<p>What conditions is MABTAS N 500 INJECTION prescribed for?</p>
<p>MABTAS N 500 INJECTION is prescribed for conditions such as Anti Cancer, Arthritis, and Osteoporosis.</p>
References
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Reviewed on 09-07-2023
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Marketer / Manufacturer Details
INTAS PHARMACEUTICALS LIMITED
Country of Origin -
India
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42658.56
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73.04 % OFF
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