RITUXEM 500MG/50ML INJECTION
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RITUXEM 500MG/50ML INJECTION
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RITUXEM 500MG/50ML INJECTION

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RITUXEM 500MG/50ML INJECTION

By EMCURE PHARMACEUTICALS LIMITED

MRP

42576.29

₹21329

49.9 % OFF

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Product Details
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About RITUXEM 500MG/50ML INJECTION

  • RITUXEM 500MG/50ML INJECTION contains the active ingredient rituximab. It is a type of medicine used to treat several serious conditions in adults, and sometimes in children aged 2 years and older. It is used to treat certain blood cancers, including Non-Hodgkin's Lymphoma (a cancer affecting white blood cells called B-lymphocytes) and Chronic Lymphocytic Leukemia (a common type of cancer affecting B-cells). RITUXEM 500MG/50ML INJECTION works by targeting and helping to remove these specific B-cells from the body. It is also used, often alongside other medicines like methotrexate, for moderate-to-severe Rheumatoid Arthritis, an autoimmune disease where the body attacks its own joints.
  • This injection is also used to treat Granulomatosis with Polyangiitis or Microscopic Polyangiitis in adults and children 2 years and older. These conditions involve inflammation of blood vessels, primarily affecting organs like the lungs and kidneys. Additionally, RITUXEM 500MG/50ML INJECTION is used for moderate to severe Pemphigus Vulgaris, a condition where the immune system causes painful blisters on the skin and the lining of the mouth, throat, nose, and genitals. Your doctor will decide if this treatment is right for you based on your specific condition and health.
  • RITUXEM 500MG/50ML INJECTION belongs to a group of medicines called anti-CD20 monoclonal antibodies, which means it's a targeted therapy. You should not receive this injection if you are allergic to rituximab or any of its other ingredients. It is also not suitable if you have a severely weakened immune system or currently have a severe active infection. Before starting treatment, it is crucial to inform your doctor if you have any history of heart problems, such as heart disease or heart failure, or if you have difficulty breathing.
  • Talk to your doctor if you have ever had a Hepatitis B infection. In some cases, this infection can become active again (reactivate) while you are receiving treatment, which can be serious. Pregnancy and breastfeeding are generally not recommended during treatment with RITUXEM 500MG/50ML INJECTION and for a period afterward, as advised by your doctor. If you can become pregnant, it is important to use effective contraception during the treatment and for 12 months after your last dose to prevent pregnancy.
  • Like all medicines, RITUXEM 500MG/50ML INJECTION can cause side effects, although not everyone gets them. Common side effects can include signs of infection (like fever), low red blood cell count, feeling dizzy, swelling (face/body), itchy skin, diarrhea, increased sweating, and changes in blood pressure (low or high). A significant concern is infusion reactions, which can occur during the injection or within 24 hours. Tell your doctor or nurse *immediately* if you experience symptoms like increased blood pressure, chest pain, headache, breathing difficulties, nausea/vomiting, skin rashes, or throat swelling during or after the infusion.
  • While receiving RITUXEM 500MG/50ML INJECTION, you will be closely monitored by healthcare professionals, usually in a hospital or clinic setting. Regular blood tests will likely be needed to check your response to treatment and monitor your blood counts and liver function. Because this medicine affects the immune system, you may be at higher risk of infections. It is important to report any signs of infection (like fever, cough, sore throat, or unusual tiredness) to your doctor promptly. Avoid receiving live vaccines during treatment and for a period advised by your doctor afterwards. Always attend your scheduled appointments and follow your doctor's advice closely.

Uses of RITUXEM 500MG/50ML INJECTION

  • For Non-Hodgkin's Lymphoma (NHL)
  • For Chronic Lymphocytic Leukemia (CLL)
  • Managing Rheumatoid Arthritis
  • Treating Granulomatosis with Polyangiitis or Microscopic Polyangiitis
  • For Pemphigus Vulgaris

Side Effects of RITUXEM 500MG/50ML INJECTION
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Side effects are unwanted symptoms caused by medicines. Even though all drugs can cause side effects, not everyone gets them. These are some side effects that may occur with RITUXEM 500MG/50ML INJECTION.

Safety Advice for RITUXEM 500MG/50ML INJECTION
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Pregnancy

Unsafe

RITUXEM 500MG/50ML INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of RITUXEM 500MG/50ML INJECTION
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  • RITUXEM 500MG/50ML INJECTION is a powerful medicine and must only be given by a healthcare professional, like a trained doctor or nurse. It is absolutely essential that you *do not* try to inject this medicine yourself. Before you receive the RITUXEM 500MG/50ML INJECTION, you will likely be given other medicines. These are called pre-medications and are given to help reduce the chance of side effects occurring during the infusion. Your doctor will carefully determine the right amount (dose) of RITUXEM 500MG/50ML INJECTION you need and how long your treatment will last. This decision is based on how severe your condition is and other important health factors. The medicine is administered directly into your vein through an intravenous (IV) drip. During and after the infusion, the medical staff will watch you closely to ensure you are tolerating the treatment well and to quickly identify and manage any potential side effects that might arise. This careful monitoring is a vital part of ensuring your safety during treatment with RITUXEM 500MG/50ML INJECTION.

How to store RITUXEM 500MG/50ML INJECTION?
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  • Keep RITUXEM 500MG INJ 50ML away from the reach of children and pets.
  • Store RITUXEM 500MG INJ 50ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of RITUXEM 500MG/50ML INJECTION
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  • Targets specific immune cells (B-lymphocytes) involved in certain diseases like cancer and rheumatoid arthritis.
  • Helps destroy cancerous B-cells in conditions like Non-Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia.
  • Blocks the growth and activation of problematic cells, offering anti-cancer effects.
  • Reduces inflammation and eases symptoms in Rheumatoid Arthritis by modulating the immune response.
  • Decreases the production of harmful substances like rheumatoid factor and pro-inflammatory cytokines in Rheumatoid Arthritis.

How to use RITUXEM 500MG/50ML INJECTION
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  • RITUXEM 500MG/50ML INJECTION is a powerful medication that must only be administered by a qualified healthcare professional, such as a trained doctor or nurse. It is crucial that this injection is never self-administered by the patient at home, as it requires specialized knowledge and monitoring during the process. Before you receive the RITUXEM 500MG/50ML INJECTION, your doctor will typically give you other medicines, often referred to as pre-medications. These are given to help reduce the likelihood and severity of potential reactions or side effects that might occur during the infusion. The exact dose of RITUXEM 500MG/50ML INJECTION and the total duration of your treatment course will be carefully determined by your doctor. This decision will be based on factors specific to your condition, including the type and severity of the disease, your overall health status, and how you respond to the treatment. The medication is administered intravenously, meaning it is slowly infused into a vein, usually over several hours in a controlled hospital or clinic setting. Throughout the entire infusion process and for a period afterward, you will be closely monitored by the medical staff to promptly identify and manage any potential side effects or infusion-related reactions, ensuring your safety throughout the treatment.

FAQs

What are the special precautions I should be aware of before starting treatment with RITUXEM 500MG/50ML INJECTION?

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Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are RITUXEM 500MG/50ML INJECTION infusion-related reactions?

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Infusion reactions occur during or within 24 hours after administering RITUXEM 500MG/50ML INJECTION. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during RITUXEM 500MG/50ML INJECTION?

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Your healthcare professional will monitor you carefully for unwanted side effects during the RITUXEM 500MG/50ML INJECTION. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Is weight gain a side effect of RITUXEM 500MG/50ML INJECTION?

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Weight gain has been reported in patients treated with RITUXEM 500MG/50ML INJECTION for non-hodgkin’s lymphoma.

Does RITUXEM 500MG/50ML INJECTION suppress the immune system?

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Yes, it can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking RITUXEM 500MG/50ML INJECTION because it may cause drug-induced immunosuppression.

What precautions should I take regarding vaccines while on RITUXEM 500MG/50ML INJECTION therapy?

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Avoid vaccines before and during RITUXEM 500MG/50ML INJECTION therapy, especially live virus vaccines if you have rheumatoid arthritis. Inform your physician if you have been vaccinated recently, as RITUXEM 500MG/50ML INJECTION may cause drug-induced immunosuppression.

What are the other important warnings or things to report while taking RITUXEM 500MG/50ML INJECTION?

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Report to your doctor immediately if you face any symptoms like chest pain, breathing difficulties, stomach pain, and skin reactions. Inform your physician if you have kidney disease or any active infection during the treatment.

What is the molecule used in RITUXEM 500MG/50ML INJECTION?

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RITUXEM 500MG/50ML INJECTION is made using the molecule RITUXIMAB.

Is RITUXEM 500MG/50ML INJECTION used for Anti Cancer treatment?

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Yes, RITUXEM 500MG/50ML INJECTION is used in the treatment of certain types of cancer.

Can RITUXEM 500MG/50ML INJECTION be prescribed for Arthritis?

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Yes, RITUXEM 500MG/50ML INJECTION is prescribed for certain types of Arthritis.

Is RITUXEM 500MG/50ML INJECTION used to treat Osteoporosis?

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Yes, RITUXEM 500MG/50ML INJECTION is prescribed for Osteoporosis.

References

Book Icon

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021).

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020).

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Marketer / Manufacturer Details

EMCURE PHARMACEUTICALS LIMITED

Country of Origin -

India

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RITUXEM 500MG/50ML INJECTION

MRP

42576.29

₹21329

49.9 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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