RITUXIPAN 500 INJECTION
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RITUXIPAN 500 INJECTION
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RITUXIPAN 500 INJECTION

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RITUXIPAN 500 INJECTION

By MANKIND PHARMA LIMITED

MRP

42577.92

₹11464

73.08 % OFF

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About RITUXIPAN 500 INJECTION

  • RITUXIPAN 500 INJECTION contains the active ingredient rituximab. It is a targeted therapy medication. Rituximab works by attaching to a specific protein called CD20 found on the surface of certain white blood cells (B-cells). By targeting these cells, RITUXIPAN 500 INJECTION helps the body fight against conditions where these B-cells are involved. This injection is used to treat several different diseases in adults. It can be used alone or with other medicines to treat certain types of cancer that affect B-cells, such as non-Hodgkin's lymphoma and chronic lymphocytic leukemia. RITUXIPAN 500 INJECTION is also used in adults with moderate to severe rheumatoid arthritis, a condition where the immune system attacks the joints. In this case, it is usually given along with another medicine called methotrexate. Furthermore, this injection treats conditions where blood vessels become inflamed, specifically granulomatosis with polyangiitis and microscopic polyangiitis, in adults and children aged 2 years and older. It also helps manage moderate to severe pemphigus vulgaris, an autoimmune disease causing painful blisters on the skin and inside the mouth.
  • RITUXIPAN 500 INJECTION belongs to a group of medicines known as monoclonal antibodies, specifically targeting CD20. You should not receive this injection if you are allergic to rituximab or any other ingredients in the medicine. It is also not suitable if you have a severely weakened immune system or currently have a serious active infection. Before receiving RITUXIPAN 500 INJECTION, it is very important to tell your doctor about your complete medical history. This includes any heart problems, such as heart disease or heart failure, or if you have difficulty breathing. If you have ever had hepatitis B infection, inform your doctor, as this medication could potentially cause the virus to become active again, which can be serious. Your doctor will likely test you for Hepatitis B before starting treatment. Getting certain live vaccines is not recommended while on this treatment and for several months afterward. This medication should not be used during pregnancy, and breastfeeding is also not advised.
  • Like all medicines, RITUXIPAN 500 INJECTION can cause side effects. Common side effects may include symptoms similar to a cold or flu, tiredness, headache, fever, chills, nausea, vomiting, or diarrhea. Some people may experience swelling in the hands or feet, dizziness, or changes in blood pressure. A decrease in blood cells, including red blood cells, white blood cells, and platelets, can also occur, which your doctor will monitor with blood tests. Serious infusion reactions can happen during the infusion or within 24 hours after receiving it. These can include symptoms like chest pain, increased blood pressure, headache, difficulty breathing, swelling of the face or throat, or skin reactions. It is crucial to tell your healthcare professional immediately if you notice any of these symptoms during or after the infusion. For women who can become pregnant, it is essential to use effective contraception during treatment and for 12 months after your last dose because the medicine stays in the body for a long time. Always discuss any concerns about side effects or other medical conditions with your doctor or nurse.

Uses of RITUXIPAN 500 INJECTION

  • Non-Hodgkin's Lymphoma (NHL): This is a type of cancer that affects the lymphatic system.
  • Chronic Lymphocytic Leukemia (CLL): This is a type of cancer that starts in the bone marrow and affects certain white blood cells.
  • Rheumatoid Arthritis: This is a chronic inflammatory disorder that typically affects the small joints of the hands and feet.
  • Granulomatosis with polyangiitis or microscopic polyangiitis: These are rare autoimmune diseases that cause inflammation of the blood vessels.
  • Pemphigus vulgaris: This is a rare autoimmune disease that causes blistering of the skin and mucous membranes.

Side Effects of RITUXIPAN 500 INJECTION
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Side effects are unwanted symptoms caused by medicines like RITUXIPAN 500 INJECTION. While all drugs can cause side effects, not everyone experiences them.

Safety Advice for RITUXIPAN 500 INJECTION
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Pregnancy

Unsafe

RITUXIPAN 500 INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 12 months after your last dose is necessary.

Dosage of RITUXIPAN 500 INJECTION
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  • This medicine, RITUXIPAN 500 INJECTION, must always be given by a qualified doctor or a trained nurse. It is crucial *not* to try and give yourself this injection. Before you receive RITUXIPAN 500 INJECTION, the healthcare team will often give you other medicines first. These 'pre-medications' are given to help reduce the chance of potential side effects or reactions to the main injection and make the treatment more comfortable for you. The exact amount of RITUXIPAN 500 INJECTION you receive, and how long you need the treatment, will be carefully decided by your doctor. They will consider several things, like how severe your condition is, your overall health, and how you respond to the medicine. This treatment is given as an intravenous infusion, which means it's delivered slowly into a vein through a drip, usually over several hours. While you are receiving the infusion and for some time afterward, nurses and doctors will monitor you very closely. They are watching carefully for any signs of unwanted side effects or reactions to ensure your safety and well-being throughout the treatment.

How to store RITUXIPAN 500 INJECTION?
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  • Keep RITUXIPAN 500MG INJ 50ML away from the reach of children and pets.
  • Store RITUXIPAN 500MG INJ 50ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of RITUXIPAN 500 INJECTION
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  • Treats certain blood cancers (like Non-Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia) by targeting and eliminating abnormal B-cells.
  • Provides anticancer effects by blocking the growth and activation of cancerous B-cells.
  • Helps manage autoimmune conditions such as Rheumatoid Arthritis by reducing the population of overactive B-cells.
  • Calms down the immune system's inflammatory response in conditions like Rheumatoid Arthritis.
  • Decreases substances that cause inflammation, like rheumatoid factor and certain cytokines, in autoimmune diseases.
  • Relieves symptoms associated with Rheumatoid Arthritis, including joint pain and swelling.

How to use RITUXIPAN 500 INJECTION
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  • RITUXIPAN 500 INJECTION should only be given to you by a qualified doctor or nurse in a clinical setting. It is crucial that you do not attempt to administer this injection yourself at home. Before you receive the RITUXIPAN 500 INJECTION, your doctor will likely give you other medications, known as pre-medications. These are important for helping to reduce the chance of experiencing certain side effects or allergic reactions during or after the infusion.
  • Your medical team will carefully determine the right dose of RITUXIPAN 500 INJECTION and how long your treatment will last. This decision is highly personalized and depends on several factors, including the specific condition being treated, how severe it is, your overall health, and your body's response to the medication. The medication is administered directly into a vein through a drip, which is called an intravenous infusion. Throughout the infusion process and for a period afterward, healthcare professionals will closely monitor you for any potential side effects or adverse reactions to ensure your safety and comfort during treatment.

FAQs

What are the special precautions I should be aware of before starting treatment with Rituxipan 500mg injection?

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Inform your doctor about your pre-existing conditions (heart, kidney, liver, hepatitis B, or lung disease) and vaccination history. It is necessary to consult a doctor if you are taking medicines for blood pressure.

What are Rituxipan 500mg infusion-related reactions?

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Infusion reactions occur during or within 24 hours after administering Rituxipan 500mg injection. The symptoms are fever, chills, cough, itchy skin, nausea, vomity, flushing, increased heart rate, and discomfort in the throat. Inform your physician immediately if you face any infusion-related reaction.

What will be the most important thing to monitor during Rituxipan 500mg injection?

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Your healthcare professional will monitor you carefully for unwanted side effects during the Rituxipan 500mg injection. You will be monitored for heart failure, increased blood pressure, or breathing failure.

Is weight gain a side effect of Rituxipan 500mg injection?

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Weight gain has been reported in patients treated with Rituxipan 500mg injection for non-hodgkin’s lymphoma.

Does Rituxipan 500mg injection suppress the immune system?

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Yes, it can suppress the immune system, and the chances of catching an infection are high. Inform your doctor if you have a severe active infection before taking Rituxipan 500mg injection because it may cause drug-induced immunosuppression.

What are the important interactions of RITUXIPAN 500 INJECTION, especially regarding vaccines?

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Avoid vaccines before and during therapy with RITUXIPAN 500 INJECTION. Inform your physician if you have been vaccinated recently, as this medicine can suppress the immune system. Vaccination with live virus vaccines is not recommended before or during treatment, especially for patients with rheumatoid arthritis.

What important advice should I follow while taking RITUXIPAN 500 INJECTION?

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Inform your physician about recent vaccinations and any active infections you have. Report symptoms like chest pain, breathing difficulties, stomach pain, or skin reactions to your doctor immediately. Also, inform your doctor if you have kidney disease, as there is limited safety data for this medicine in renal failure patients.

What is the main molecule in RITUXIPAN 500 INJECTION?

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RITUXIPAN 500 INJECTION contains RITUXIMAB.

Is RITUXIPAN 500 INJECTION used for treating cancer?

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Yes, RITUXIPAN 500 INJECTION is used in the treatment of Anti Cancer conditions.

Can RITUXIPAN 500 INJECTION be used for Arthritis?

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Yes, RITUXIPAN 500 INJECTION is prescribed for Arthritis.

Is RITUXIPAN 500 INJECTION used for Osteoporosis?

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Yes, RITUXIPAN 500 INJECTION is prescribed for Osteoporosis.

References

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HIGHLIGHTS OF PRESCRIBING INFORMATION. (2021). Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/103705s5464lbl.pdf

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ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (2020). Available at: https://www.ema.europa.eu/en/documents/product-information/mabthera-epar-product-information_en.pdf

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Marketer / Manufacturer Details

MANKIND PHARMA LIMITED

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India

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MRP

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₹11464

73.08 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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